Neonatal NK cells target the mouse duct epithelium via Nkg2d and drive tissue-specific injury in experimental biliary atresia

Journal of Clinical Investigation

Volumn 119, Issue 8, 2009, Pages 2281-2290

  Shivakumar, Pranavkumar ^a   Sabla, Gregg E ^a   Whitington, Peter ^b   Chougnet, Claire A ^a   Bezerra, Jorge A ^a,c  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2 INTEGRIN; CD11B ANTIGEN; CD19 ANTIGEN; CD3 ANTIGEN; CD4 ANTIGEN; CD8 ANTIGEN; CYTOKINE; NATURAL KILLER CELL RECEPTOR NKG2D;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BILE DUCT ATRESIA; BILE FLOW; CELL ACTIVATION; CELL POPULATION; CONTROLLED STUDY; CYTOTOXICITY; DUODENUM; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; INFANT; INNATE IMMUNITY; INTRAHEPATIC BILE DUCT; LIVER; LIVER FAILURE; MOUSE; NATURAL KILLER CELL; NEWBORN; NONHUMAN; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; ROTAVIRUS; TISSUE INJURY; TISSUE SPECIFICITY;

ANIMALS; ANIMALS, NEWBORN; BILE DUCTS, EXTRAHEPATIC; BILIARY ATRESIA; CD8-POSITIVE T-LYMPHOCYTES; CYTOTOXICITY, IMMUNOLOGIC; DISEASE MODELS, ANIMAL; HUMANS; IMMUNITY, INNATE; INFANT; KILLER CELLS, NATURAL; LIVER; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED BALB C; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY K; ORGAN SPECIFICITY; ROTAVIRUS;

EID: 68849092071     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI38879     Document Type: Article

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