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Volumn 8, Issue 8, 2013, Pages

B Cell Deficient Mice Are Protected from Biliary Obstruction in the Rotavirus-Induced Mouse Model of Biliary Atresia

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE ACTIVATION; BILE DUCT ATRESIA; CD4+ T LYMPHOCYTE; CHOLESTASIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; DISEASE FREE SURVIVAL; FEMALE; HEPATITIS; HYPERBILIRUBINEMIA; LYMPHOCYTE DEPLETION; MOUSE; NONHUMAN; REGULATORY T LYMPHOCYTE; ROTAVIRUS; ROTAVIRUS INFECTION; SIMIAN ROTAVIRUS; SURVIVAL RATE; TH1 CELL; WILD TYPE;

EID: 84882586277     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0073644     Document Type: Article
Times cited : (37)

References (60)
  • 1
    • 84873364829 scopus 로고    scopus 로고
    • Clues to the etiology of bile duct injury in biliary atresia. Semin Liver
    • Mack CL, Feldman AG, Sokol RJ, (2012). Clues to the etiology of bile duct injury in biliary atresia. Semin Liver Dis. 32(4):: 307-16.
    • (2012) Dis , vol.32 , pp. 307-316
    • Mack, C.L.1    Feldman, A.G.2    Sokol, R.J.3
  • 2
    • 34548131082 scopus 로고    scopus 로고
    • The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease
    • doi: 10.1055/s-2007-985068
    • Mack CL, (2007) The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease. Semin Liver Dis 27: 233-242. doi:10.1055/s-2007-985068. PubMed: 17682970.
    • (2007) Semin Liver Dis , vol.27 , pp. 233-242
    • Mack, C.L.1
  • 3
    • 34548319067 scopus 로고    scopus 로고
    • Screening and outcomes in biliary atresia: summary of a National Institutes of Health workshop
    • doi: 10.1002/hep.21790
    • Sokol RJ, Shepherd RW, Superina R, Bezerra JA, Robuck P, et al. (2007) Screening and outcomes in biliary atresia: summary of a National Institutes of Health workshop. Hepatology 46: 566-581. doi:10.1002/hep.21790. PubMed: 17661405.
    • (2007) Hepatology , vol.46 , pp. 566-581
    • Sokol, R.J.1    Shepherd, R.W.2    Superina, R.3    Bezerra, J.A.4    Robuck, P.5
  • 4
    • 12844285598 scopus 로고    scopus 로고
    • Outcome in adulthood of biliary atresia: a study of 63 patients who survived for over 20 years with their native liver
    • doi: 10.1002/hep.20547
    • Lykavieris P, Chardot C, Sokhn M, Gauthier F, Valayer J, et al. (2005) Outcome in adulthood of biliary atresia: a study of 63 patients who survived for over 20 years with their native liver. Hepatology 41: 366-371. doi:10.1002/hep.20547. PubMed: 15660386.
    • (2005) Hepatology , vol.41 , pp. 366-371
    • Lykavieris, P.1    Chardot, C.2    Sokhn, M.3    Gauthier, F.4    Valayer, J.5
  • 5
    • 0642315150 scopus 로고    scopus 로고
    • Pathogenesis and outcome of biliary atresia: current concepts
    • doi: 10.1097/00005176-200307000-00003
    • Sokol RJ, Mack C, Narkewicz MR, Karrer FM, (2003) Pathogenesis and outcome of biliary atresia: current concepts. J Pediatr Gastroenterol Nutr 37: 4-21. doi:10.1097/00005176-200307000-00003. PubMed: 12827000.
    • (2003) J Pediatr Gastroenterol Nutr , vol.37 , pp. 4-21
    • Sokol, R.J.1    Mack, C.2    Narkewicz, M.R.3    Karrer, F.M.4
  • 6
    • 19244364586 scopus 로고    scopus 로고
    • Detection of group C rotavirus in infants with extrahepatic biliary atresia
    • doi: 10.1093/infdis/174.1.8
    • Riepenhoff-Talty M, Gouvea V, Evans MJ, Svensson L, Hoffenberg E, et al. (1996) Detection of group C rotavirus in infants with extrahepatic biliary atresia. J Infect Dis 174: 8-15. doi:10.1093/infdis/174.1.8. PubMed: 8656017.
    • (1996) J Infect Dis , vol.174 , pp. 8-15
    • Riepenhoff-Talty, M.1    Gouvea, V.2    Evans, M.J.3    Svensson, L.4    Hoffenberg, E.5
  • 7
    • 17344365858 scopus 로고    scopus 로고
    • Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts
    • doi: 10.1002/hep.510270603
    • Tyler KL, Sokol RJ, Oberhaus SM, Le M, Karrer FM, et al. (1998) Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts. Hepatology 27: 1475-1482. doi:10.1002/hep.510270603. PubMed: 9620316.
    • (1998) Hepatology , vol.27 , pp. 1475-1482
    • Tyler, K.L.1    Sokol, R.J.2    Oberhaus, S.M.3    Le, M.4    Karrer, F.M.5
  • 8
    • 0032909874 scopus 로고    scopus 로고
    • Biliary atresia and cytomegalovirus infection: a DNA study
    • doi: 10.1007/s100249900083
    • Jevon GP, Dimmick JE, (1999) Biliary atresia and cytomegalovirus infection: a DNA study. Pediatr Dev Pathol 2: 11-14. doi:10.1007/s100249900083. PubMed: 9841700.
    • (1999) Pediatr Dev Pathol , vol.2 , pp. 11-14
    • Jevon, G.P.1    Dimmick, J.E.2
  • 9
    • 0027479773 scopus 로고
    • Genetics, immunology, and biliary atresia: an opening or a diversion?
    • doi: 10.1097/00005176-199302000-00001
    • Schreiber RA, Kleinman RE, (1993) Genetics, immunology, and biliary atresia: an opening or a diversion? J Pediatr Gastroenterol Nutr 16: 111-113. doi:10.1097/00005176-199302000-00001. PubMed: 8450373.
    • (1993) J Pediatr Gastroenterol Nutr , vol.16 , pp. 111-113
    • Schreiber, R.A.1    Kleinman, R.E.2
  • 10
    • 0028352170 scopus 로고
    • Extrahepatic biliary atresia: a first-trimester event? Clues from light microscopy and immunohistochemistry
    • doi: 10.1016/0022-3468(94)90377-8
    • Tan CE, Driver M, Howard ER, Moscoso GJ, (1994) Extrahepatic biliary atresia: a first-trimester event? Clues from light microscopy and immunohistochemistry. J Pediatr Surg 29: 808-814. doi:10.1016/0022-3468(94)90377-8. PubMed: 7521396.
    • (1994) J Pediatr Surg , vol.29 , pp. 808-814
    • Tan, C.E.1    Driver, M.2    Howard, E.R.3    Moscoso, G.J.4
  • 11
    • 0027522745 scopus 로고
    • Group A rotaviruses produce extrahepatic biliary obstruction in orally inoculated newborn mice
    • doi: 10.1203/00006450-199333040-00016
    • Riepenhoff-Talty M, Schaekel K, Clark HF, Mueller W, Uhnoo I, et al. (1993) Group A rotaviruses produce extrahepatic biliary obstruction in orally inoculated newborn mice. Pediatr Res 33: 394-399. doi:10.1203/00006450-199333040-00016. PubMed: 8386833.
    • (1993) Pediatr Res , vol.33 , pp. 394-399
    • Riepenhoff-Talty, M.1    Schaekel, K.2    Clark, H.F.3    Mueller, W.4    Uhnoo, I.5
  • 12
    • 0031961096 scopus 로고    scopus 로고
    • Diverse morphology of biliary atresia in an animal model
    • doi: 10.1016/S0168-8278(98)80283-3
    • Petersen C, Grasshoff S, Luciano L, (1998) Diverse morphology of biliary atresia in an animal model. J Hepatol 28: 603-607. doi:10.1016/S0168-8278(98)80283-3. PubMed: 9566828.
    • (1998) J Hepatol , vol.28 , pp. 603-607
    • Petersen, C.1    Grasshoff, S.2    Luciano, L.3
  • 13
    • 18844416103 scopus 로고    scopus 로고
    • Armed CD4+ Th1 effector cells and activated macrophages participate in bile duct injury in murine biliary atresia
    • doi: 10.1016/j.clim.2005.01.012
    • Mack CL, Tucker RM, Sokol RJ, Kotzin BL, (2005) Armed CD4+ Th1 effector cells and activated macrophages participate in bile duct injury in murine biliary atresia. Clin Immunol 115: 200-209. doi:10.1016/j.clim.2005.01.012. PubMed: 15885644.
    • (2005) Clin Immunol , vol.115 , pp. 200-209
    • Mack, C.L.1    Tucker, R.M.2    Sokol, R.J.3    Kotzin, B.L.4
  • 14
    • 4043070842 scopus 로고    scopus 로고
    • Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia
    • doi: 10.1172/JCI200421153
    • Shivakumar P, Campbell KM, Sabla GE, Miethke A, Tiao G, et al. (2004) Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-gamma in experimental biliary atresia. J Clin Invest 114: 322-329. doi:10.1172/JCI200421153. PubMed: 15286798.
    • (2004) J Clin Invest , vol.114 , pp. 322-329
    • Shivakumar, P.1    Campbell, K.M.2    Sabla, G.E.3    Miethke, A.4    Tiao, G.5
  • 15
    • 33750999089 scopus 로고    scopus 로고
    • Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia
    • doi: 10.1002/hep.21366
    • Mack CL, Tucker RM, Lu BR, Sokol RJ, Fontenot AP, et al. (2006) Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia. Hepatology 44: 1231-1239. doi:10.1002/hep.21366. PubMed: 17058262.
    • (2006) Hepatology , vol.44 , pp. 1231-1239
    • Mack, C.L.1    Tucker, R.M.2    Lu, B.R.3    Sokol, R.J.4    Fontenot, A.P.5
  • 16
    • 34447098108 scopus 로고    scopus 로고
    • Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia
    • doi: 10.1053/j.gastro.2007.04.031
    • Shivakumar P, Sabla G, Mohanty S, McNeal M, Ward R, et al. (2007) Effector role of neonatal hepatic CD8+ lymphocytes in epithelial injury and autoimmunity in experimental biliary atresia. Gastroenterology 133: 268-277. doi:10.1053/j.gastro.2007.04.031. PubMed: 17631148.
    • (2007) Gastroenterology , vol.133 , pp. 268-277
    • Shivakumar, P.1    Sabla, G.2    Mohanty, S.3    McNeal, M.4    Ward, R.5
  • 17
    • 33344474600 scopus 로고    scopus 로고
    • B cell-deficient NOD.H-2h4 mice have CD4+CD25+ T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis
    • doi: 10.1084/jem.20051438
    • Yu S, Maiti PK, Dyson M, Jain R, Braley-Mullen H, (2006) B cell-deficient NOD.H-2h4 mice have CD4+CD25+ T regulatory cells that inhibit the development of spontaneous autoimmune thyroiditis. J Exp Med 203: 349-358. doi:10.1084/jem.20051438. PubMed: 16446379.
    • (2006) J Exp Med , vol.203 , pp. 349-358
    • Yu, S.1    Maiti, P.K.2    Dyson, M.3    Jain, R.4    Braley-Mullen, H.5
  • 18
    • 0031882091 scopus 로고    scopus 로고
    • A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice
    • 9551955
    • Chan O, Shlomchik MJ, (1998) A new role for B cells in systemic autoimmunity: B cells promote spontaneous T cell activation in MRL-lpr/lpr mice. J Immunol 160: 51-59. PubMed: 9551955.
    • (1998) J Immunol , vol.160 , pp. 51-59
    • Chan, O.1    Shlomchik, M.J.2
  • 19
    • 14844347864 scopus 로고    scopus 로고
    • Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis
    • 15749919
    • O'Neill SK, Shlomchik MJ, Glant TT, Cao Y, Doodes PD, et al. (2005) Antigen-specific B cells are required as APCs and autoantibody-producing cells for induction of severe autoimmune arthritis. J Immunol 174: 3781-3788. PubMed: 15749919.
    • (2005) J Immunol , vol.174 , pp. 3781-3788
    • O'Neill, S.K.1    Shlomchik, M.J.2    Glant, T.T.3    Cao, Y.4    Doodes, P.D.5
  • 20
    • 0032532294 scopus 로고    scopus 로고
    • B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice
    • 9780157
    • Serreze DV, Fleming SA, Chapman HD, Richard SD, Leiter EH, et al. (1998) B lymphocytes are critical antigen-presenting cells for the initiation of T cell-mediated autoimmune diabetes in nonobese diabetic mice. J Immunol 161: 3912-3918. PubMed: 9780157.
    • (1998) J Immunol , vol.161 , pp. 3912-3918
    • Serreze, D.V.1    Fleming, S.A.2    Chapman, H.D.3    Richard, S.D.4    Leiter, E.H.5
  • 21
    • 38149098399 scopus 로고    scopus 로고
    • B cell-directed therapies for autoimmune disease and correlates of disease response and relapse
    • doi: 10.1016/j.jaci.2007.12.053, quiz 22-13
    • Levesque MC, St Clair EW, (2008) B cell-directed therapies for autoimmune disease and correlates of disease response and relapse. J Allergy Clin Immunol 121: 13-21; quiz 22-13 doi:10.1016/j.jaci.2007.12.053. PubMed: 18206502.
    • (2008) J Allergy Clin Immunol , vol.121 , pp. 13-21
    • Levesque, M.C.1    St Clair, E.W.2
  • 22
    • 0019466397 scopus 로고
    • Immunoglobulin deposits in the biliary remnants of extrahepatic biliary atresia: a study by immunoperoxidase staining in 128 infants
    • doi: 10.1111/j.1365-2559.1981.tb01779.x
    • Hadchouel M, Hugon RN, Odievre M, (1981) Immunoglobulin deposits in the biliary remnants of extrahepatic biliary atresia: a study by immunoperoxidase staining in 128 infants. Histopathology 5: 217-221. doi:10.1111/j.1365-2559.1981.tb01779.x. PubMed: 7216182.
    • (1981) Histopathology , vol.5 , pp. 217-221
    • Hadchouel, M.1    Hugon, R.N.2    Odievre, M.3
  • 23
    • 78049474694 scopus 로고    scopus 로고
    • Alpha-enolase autoantibodies cross-reactive to viral proteins in a mouse model of biliary atresia
    • doi: 10.1053/j.gastro.2010.07.042
    • Lu BR, Brindley SM, Tucker RM, Lambert CL, Mack CL, (2010) Alpha-enolase autoantibodies cross-reactive to viral proteins in a mouse model of biliary atresia. Gastroenterology 139: 1753-1761. doi:10.1053/j.gastro.2010.07.042. PubMed: 20659472.
    • (2010) Gastroenterology , vol.139 , pp. 1753-1761
    • Lu, B.R.1    Brindley, S.M.2    Tucker, R.M.3    Lambert, C.L.4    Mack, C.L.5
  • 24
    • 79955788484 scopus 로고    scopus 로고
    • Identification of a novel autoantigen in inflammatory bowel disease by protein microarray
    • doi: 10.1002/ibd.21508
    • Vermeulen N, de Béeck KO, Vermeire S, Van Steen K, Michiels G, et al. (2011) Identification of a novel autoantigen in inflammatory bowel disease by protein microarray. Inflamm Bowel Dis 17: 1291-1300. doi:10.1002/ibd.21508. PubMed: 21560193.
    • (2011) Inflamm Bowel Dis , vol.17 , pp. 1291-1300
    • Vermeulen, N.1    de Béeck, K.O.2    Vermeire, S.3    Van Steen, K.4    Michiels, G.5
  • 25
    • 0037100435 scopus 로고    scopus 로고
    • B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta
    • 12097390
    • Pelanda R, Braun U, Hobeika E, Nussenzweig MC, Reth M, (2002) B cell progenitors are arrested in maturation but have intact VDJ recombination in the absence of Ig-alpha and Ig-beta. J Immunol 169: 865-872. PubMed: 12097390.
    • (2002) J Immunol , vol.169 , pp. 865-872
    • Pelanda, R.1    Braun, U.2    Hobeika, E.3    Nussenzweig, M.C.4    Reth, M.5
  • 26
    • 0032589471 scopus 로고    scopus 로고
    • Mutations in Igalpha (CD79a) result in a complete block in B-cell development
    • doi: 10.1172/JCI7696
    • Minegishi Y, Coustan-Smith E, Rapalus L, Ersoy F, Campana D, et al. (1999) Mutations in Igalpha (CD79a) result in a complete block in B-cell development. J Clin Invest 104: 1115-1121. doi:10.1172/JCI7696. PubMed: 10525050.
    • (1999) J Clin Invest , vol.104 , pp. 1115-1121
    • Minegishi, Y.1    Coustan-Smith, E.2    Rapalus, L.3    Ersoy, F.4    Campana, D.5
  • 27
    • 0029913115 scopus 로고    scopus 로고
    • Regulation of an early developmental checkpoint in the B cell pathway by Ig beta
    • doi: 10.1126/science.272.5260.411
    • Gong S, Nussenzweig MC, (1996) Regulation of an early developmental checkpoint in the B cell pathway by Ig beta. Science 272: 411-414. doi:10.1126/science.272.5260.411. PubMed: 8602530.
    • (1996) Science , vol.272 , pp. 411-414
    • Gong, S.1    Nussenzweig, M.C.2
  • 28
    • 70350041702 scopus 로고    scopus 로고
    • Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia
    • doi: 10.1111/j.1478-3231.2008.01921.x
    • Barnes BH, Tucker RM, Wehrmann F, Mack DG, Ueno Y, et al. (2009) Cholangiocytes as immune modulators in rotavirus-induced murine biliary atresia. Liver Int 29: 1253-1261. doi:10.1111/j.1478-3231.2008.01921.x. PubMed: 19040538.
    • (2009) Liver Int , vol.29 , pp. 1253-1261
    • Barnes, B.H.1    Tucker, R.M.2    Wehrmann, F.3    Mack, D.G.4    Ueno, Y.5
  • 29
    • 51649091745 scopus 로고    scopus 로고
    • Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B cell-depleting therapy with rituximab
    • doi: 10.1182/blood-2007-12-129262
    • Stasi R, Cooper N, Del Poeta G, Stipa E, Laura Evangelista M, et al. (2008) Analysis of regulatory T-cell changes in patients with idiopathic thrombocytopenic purpura receiving B cell-depleting therapy with rituximab. Blood 112: 1147-1150. doi:10.1182/blood-2007-12-129262. PubMed: 18375792.
    • (2008) Blood , vol.112 , pp. 1147-1150
    • Stasi, R.1    Cooper, N.2    Del Poeta, G.3    Stipa, E.4    Laura Evangelista, M.5
  • 30
    • 80555149788 scopus 로고    scopus 로고
    • B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis
    • doi: 10.4049/jimmunol.1101844
    • Hamel KM, Cao Y, Ashaye S, Wang Y, Dunn R, et al. (2011) B cell depletion enhances T regulatory cell activity essential in the suppression of arthritis. J Immunol 187: 4900-4906. doi:10.4049/jimmunol.1101844. PubMed: 21948985.
    • (2011) J Immunol , vol.187 , pp. 4900-4906
    • Hamel, K.M.1    Cao, Y.2    Ashaye, S.3    Wang, Y.4    Dunn, R.5
  • 31
    • 33947118656 scopus 로고    scopus 로고
    • Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis
    • doi: 10.1016/j.clim.2007.03.366
    • Sfikakis PP, Souliotis VL, Fragiadaki KG, Moutsopoulos HM, Boletis JN, et al. (2007) Increased expression of the FoxP3 functional marker of regulatory T cells following B cell depletion with rituximab in patients with lupus nephritis. Clin Immunol 123: 66-73. doi:10.1016/j.clim.2007.03.366. PubMed: 17275413.
    • (2007) Clin Immunol , vol.123 , pp. 66-73
    • Sfikakis, P.P.1    Souliotis, V.L.2    Fragiadaki, K.G.3    Moutsopoulos, H.M.4    Boletis, J.N.5
  • 32
    • 84873748148 scopus 로고    scopus 로고
    • Lymphotoxin alpha(1) beta(2) expression on B cells is required for follicular dendritic cell activation during the germinal center response
    • doi: 10.1002/eji.201242471
    • Myers RC, King RG, Carter RH, Justement LB, (2013) Lymphotoxin alpha(1) beta(2) expression on B cells is required for follicular dendritic cell activation during the germinal center response. Eur J Immunol 43: 348-359. doi:10.1002/eji.201242471. PubMed: 23112125.
    • (2013) Eur J Immunol , vol.43 , pp. 348-359
    • Myers, R.C.1    King, R.G.2    Carter, R.H.3    Justement, L.B.4
  • 33
    • 80053265930 scopus 로고    scopus 로고
    • Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia
    • 21957172
    • Saxena V, Shivakumar P, Sabla G, Mourya R, Chougnet C, et al. (2011) Dendritic cells regulate natural killer cell activation and epithelial injury in experimental biliary atresia. Sci Transl Med 3: 102ra194. PubMed: 21957172.
    • (2011) Sci Transl Med , vol.3 , pp. 102-194
    • Saxena, V.1    Shivakumar, P.2    Sabla, G.3    Mourya, R.4    Chougnet, C.5
  • 34
    • 0033214474 scopus 로고    scopus 로고
    • B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity
    • doi: 10490951
    • Chan OT, Madaio MP, Shlomchik MJ, (1999) B cells are required for lupus nephritis in the polygenic, Fas-intact MRL model of systemic autoimmunity. J Immunol 163: 3592-3596. PubMed: 10490951.
    • (1999) J Immunol , vol.163 , pp. 3592-3596
    • Chan, O.T.1    Madaio, M.P.2    Shlomchik, M.J.3
  • 35
    • 0034671991 scopus 로고    scopus 로고
    • Early requirement for B cells for development of spontaneous autoimmune thyroiditis in NOD.H-2h4 mice
    • 11120860
    • Braley-Mullen H, Yu S, (2000) Early requirement for B cells for development of spontaneous autoimmune thyroiditis in NOD.H-2h4 mice. J Immunol 165: 7262-7269. PubMed: 11120860.
    • (2000) J Immunol , vol.165 , pp. 7262-7269
    • Braley-Mullen, H.1    Yu, S.2
  • 36
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • doi: 10.1084/jem.189.10.1639
    • Chan OT, Hannum LG, Haberman AM, Madaio MP, Shlomchik MJ, (1999) A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189: 1639-1648. doi:10.1084/jem.189.10.1639. PubMed: 10330443.
    • (1999) J Exp Med , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 37
    • 33646036416 scopus 로고    scopus 로고
    • B cells as antigen presenting cells
    • doi: 10.1016/j.cellimm.2006.02.005
    • Rodríguez-Pinto D, (2005) B cells as antigen presenting cells. Cell Immunol 238: 67-75. doi:10.1016/j.cellimm.2006.02.005. PubMed: 16574086.
    • (2005) Cell Immunol , vol.238 , pp. 67-75
    • Rodríguez-Pinto, D.1
  • 38
    • 0033577903 scopus 로고    scopus 로고
    • A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus
    • doi: 10.1084/jem.189.10.1639
    • Chan OT, Hannum LG, Haberman AM, Madaio MP, Shlomchik MJ, (1999) A novel mouse with B cells but lacking serum antibody reveals an antibody-independent role for B cells in murine lupus. J Exp Med 189: 1639-1648. doi:10.1084/jem.189.10.1639. PubMed: 10330443.
    • (1999) J Exp Med , vol.189 , pp. 1639-1648
    • Chan, O.T.1    Hannum, L.G.2    Haberman, A.M.3    Madaio, M.P.4    Shlomchik, M.J.5
  • 39
    • 0032145276 scopus 로고    scopus 로고
    • B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice
    • 9686575
    • Falcone M, Lee J, Patstone G, Yeung B, Sarvetnick N, (1998) B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in nonobese diabetic mice. J Immunol 161: 1163-1168. PubMed: 9686575.
    • (1998) J Immunol , vol.161 , pp. 1163-1168
    • Falcone, M.1    Lee, J.2    Patstone, G.3    Yeung, B.4    Sarvetnick, N.5
  • 40
    • 0033564970 scopus 로고    scopus 로고
    • I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice
    • doi: 10395666
    • Noorchashm H, Lieu YK, Noorchashm N, Rostami SY, Greeley SA, et al. (1999) I-Ag7-mediated antigen presentation by B lymphocytes is critical in overcoming a checkpoint in T cell tolerance to islet beta cells of nonobese diabetic mice. J Immunol 163: 743-750. PubMed: 10395666.
    • (1999) J Immunol , vol.163 , pp. 743-750
    • Noorchashm, H.1    Lieu, Y.K.2    Noorchashm, N.3    Rostami, S.Y.4    Greeley, S.A.5
  • 41
    • 0032729174 scopus 로고    scopus 로고
    • B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide
    • doi: 10.1002/(SICI)1521-4141(199911)29:11
    • Lyons JA, San M, Happ MP, Cross AH, (1999) B cells are critical to induction of experimental allergic encephalomyelitis by protein but not by a short encephalitogenic peptide. Eur J Immunol 29: 3432-3439. doi:10.1002/(SICI)1521-4141(199911)29:11. PubMed: 10556797.
    • (1999) Eur J Immunol , vol.29 , pp. 3432-3439
    • Lyons, J.A.1    San, M.2    Happ, M.P.3    Cross, A.H.4
  • 42
    • 0023223175 scopus 로고
    • T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes
    • 2952725
    • Ron Y, Sprent J, (1987) T cell priming in vivo: a major role for B cells in presenting antigen to T cells in lymph nodes. J Immunol 138: 2848-2856. PubMed: 2952725.
    • (1987) J Immunol , vol.138 , pp. 2848-2856
    • Ron, Y.1    Sprent, J.2
  • 43
    • 0023930695 scopus 로고
    • The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice
    • 2453554
    • Kurt-Jones EA, Liano D, HayGlass KA, Benacerraf B, Sy MS,et al (1988) The role of antigen-presenting B cells in T cell priming in vivo. Studies of B cell-deficient mice. J Immunol 140: 3773-3778. PubMed: 2453554.
    • (1988) J Immunol , vol.140 , pp. 3773-3778
    • Kurt-Jones, E.A.1    Liano, D.2
  • 44
    • 77957111769 scopus 로고    scopus 로고
    • TLR and B cell receptor signals to B cells differentially program primary and memory Th1 responses to Salmonella enterica
    • doi: 10.4049/jimmunol.1001431
    • Barr TA, Brown S, Mastroeni P, Gray D,. (2010) TLR and B cell receptor signals to B cells differentially program primary and memory Th1 responses to Salmonella enterica. J Immunol 185: 2783-2789. doi:10.4049/jimmunol.1001431. PubMed: 20675594.
    • (2010) J Immunol , vol.185 , pp. 2783-2789
    • Barr, T.A.1    Brown, S.2    Mastroeni, P.3    Gray, D.4
  • 45
    • 0033964726 scopus 로고    scopus 로고
    • Igh-6(-/-) (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar typhimurium and show impaired Th1 T-cell responses to Salmonella antigens
    • doi: 10.1128/IAI.68.1.46-53.2000
    • Mastroeni P, Simmons C, Fowler R, Hormaeche CE, Dougan G, (2000) Igh-6(-/-) (B-cell-deficient) mice fail to mount solid acquired resistance to oral challenge with virulent Salmonella enterica serovar typhimurium and show impaired Th1 T-cell responses to Salmonella antigens. Infect Immun 68: 46-53. doi:10.1128/IAI.68.1.46-53.2000. PubMed: 10603367.
    • (2000) Infect Immun , vol.68 , pp. 46-53
    • Mastroeni, P.1    Simmons, C.2    Fowler, R.3    Hormaeche, C.E.4    Dougan, G.5
  • 46
    • 0037388954 scopus 로고    scopus 로고
    • Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo
    • doi: 10.1084/jem.20021290
    • Linton PJ, Bautista B, Biederman E, Bradley ES, Harbertson J, et al. (2003) Costimulation via OX40L expressed by B cells is sufficient to determine the extent of primary CD4 cell expansion and Th2 cytokine secretion in vivo. J Exp Med 197: 875-883. doi:10.1084/jem.20021290. PubMed: 12668647.
    • (2003) J Exp Med , vol.197 , pp. 875-883
    • Linton, P.J.1    Bautista, B.2    Biederman, E.3    Bradley, E.S.4    Harbertson, J.5
  • 47
    • 0034668824 scopus 로고    scopus 로고
    • A critical role for B cells in the development of memory CD4 cells
    • 11067910
    • Linton PJ, Harbertson J, Bradley LM, (2000) A critical role for B cells in the development of memory CD4 cells. J Immunol 165: 5558-5565. PubMed: 11067910.
    • (2000) J Immunol , vol.165 , pp. 5558-5565
    • Linton, P.J.1    Harbertson, J.2    Bradley, L.M.3
  • 48
    • 17444384215 scopus 로고    scopus 로고
    • B cells can prime naive CD4+ T cells in vivo in the absence of other professional antigen-presenting cells in a CD154-CD40-dependent manner
    • doi: 10.1002/eji.200425732
    • Rodríguez-Pinto D, Moreno J, (2005) B cells can prime naive CD4+ T cells in vivo in the absence of other professional antigen-presenting cells in a CD154-CD40-dependent manner. Eur J Immunol 35: 1097-1105. doi:10.1002/eji.200425732. PubMed: 15756646.
    • (2005) Eur J Immunol , vol.35 , pp. 1097-1105
    • Rodríguez-Pinto, D.1    Moreno, J.2
  • 49
    • 13444252282 scopus 로고    scopus 로고
    • Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial
    • doi: 10.1002/art.20858
    • Sfikakis PP, Boletis JN, Lionaki S, Vigklis V, Fragiadaki KG, et al. (2005) Remission of proliferative lupus nephritis following B cell depletion therapy is preceded by down-regulation of the T cell costimulatory molecule CD40 ligand: an open-label trial. Arthritis Rheum 52: 501-513. doi:10.1002/art.20858. PubMed: 15693003.
    • (2005) Arthritis Rheum , vol.52 , pp. 501-513
    • Sfikakis, P.P.1    Boletis, J.N.2    Lionaki, S.3    Vigklis, V.4    Fragiadaki, K.G.5
  • 50
    • 1842732224 scopus 로고    scopus 로고
    • Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis
    • doi: 10.1084/jem.20031579
    • Viglietta V, Baecher-Allan C, Weiner HL, Hafler DA, (2004) Loss of functional suppression by CD4+CD25+ regulatory T cells in patients with multiple sclerosis. J Exp Med 199: 971-979. doi:10.1084/jem.20031579. PubMed: 15067033.
    • (2004) J Exp Med , vol.199 , pp. 971-979
    • Viglietta, V.1    Baecher-Allan, C.2    Weiner, H.L.3    Hafler, D.A.4
  • 51
    • 33747605602 scopus 로고    scopus 로고
    • Early rheumatoid arthritis is associated with a deficit in the CD4+CD25high regulatory T cell population in peripheral blood
    • doi: 10.1093/rheumatology/kel089
    • Lawson CA, Brown AK, Bejarano V, Douglas SH, Burgoyne CH, et al. (2006) Early rheumatoid arthritis is associated with a deficit in the CD4+CD25high regulatory T cell population in peripheral blood. Rheumatology (Oxf) 45: 1210-1217. doi:10.1093/rheumatology/kel089. PubMed: 16571607.
    • (2006) Rheumatology (Oxf) , vol.45 , pp. 1210-1217
    • Lawson, C.A.1    Brown, A.K.2    Bejarano, V.3    Douglas, S.H.4    Burgoyne, C.H.5
  • 52
    • 12144249838 scopus 로고    scopus 로고
    • Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
    • doi: 10.2337/diabetes.54.1.92
    • Lindley S, Dayan CM, Bishop A, Roep BO, Peakman M, et al. (2005) Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes. Diabetes 54: 92-99. doi:10.2337/diabetes.54.1.92. PubMed: 15616015.
    • (2005) Diabetes , vol.54 , pp. 92-99
    • Lindley, S.1    Dayan, C.M.2    Bishop, A.3    Roep, B.O.4    Peakman, M.5
  • 53
    • 77951619946 scopus 로고    scopus 로고
    • Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia
    • Miethke AG, Saxena V, Shivakumar P, Sabla GE, Simmons J, et al. (2010) Post-natal paucity of regulatory T cells and control of NK cell activation in experimental biliary atresia. J Hepatol 52(5):718-26.
    • (2010) J Hepatol
    • Miethke, A.G.1    Saxena, V.2    Shivakumar, P.3    Sabla, G.E.4    Simmons, J.5
  • 54
    • 84884418640 scopus 로고    scopus 로고
    • Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia
    • Tucker RM, Feldman AG, Fenner EK, Mack CL, (2013) Regulatory T cells inhibit Th1 cell-mediated bile duct injury in murine biliary atresia. J Hepatol [Epub ahead of print].
    • (2013) J Hepatol
    • Tucker, R.M.1    Feldman, A.G.2    Fenner, E.K.3    Mack, C.L.4
  • 55
    • 84859137659 scopus 로고    scopus 로고
    • Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells
    • Brindley SM, Lanham AM, Karrer FM, Tucker RM, Fontenot AP, Mack CL, (2012). Cytomegalovirus-specific T-cell reactivity in biliary atresia at the time of diagnosis is associated with deficits in regulatory T cells. Hepatology. 55(4):1130-8.
    • (2012) Hepatology , pp. 55
    • Brindley, S.M.1    Lanham, A.M.2    Karrer, F.M.3    Tucker, R.M.4    Fontenot, A.P.5    Mack, C.L.6
  • 56
    • 4043072255 scopus 로고    scopus 로고
    • Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease
    • doi: 10.1172/JCI200420855
    • Olson TS, Bamias G, Naganuma M, Rivera-Nieves J, Burcin TL, et al. (2004) Expanded B cell population blocks regulatory T cells and exacerbates ileitis in a murine model of Crohn disease. J Clin Invest 114: 389-398. doi:10.1172/JCI200420855. PubMed: 15286805.
    • (2004) J Clin Invest , vol.114 , pp. 389-398
    • Olson, T.S.1    Bamias, G.2    Naganuma, M.3    Rivera-Nieves, J.4    Burcin, T.L.5
  • 57
    • 33746961890 scopus 로고    scopus 로고
    • Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks
    • doi: 10.1002/art.22025
    • Cohen SB, Emery P, Greenwald MW, Dougados M, Furie RA, et al. (2006) Rituximab for rheumatoid arthritis refractory to anti-tumor necrosis factor therapy: Results of a multicenter, randomized, double-blind, placebo-controlled, phase III trial evaluating primary efficacy and safety at twenty-four weeks. Arthritis Rheum 54: 2793-2806. doi:10.1002/art.22025. PubMed: 16947627.
    • (2006) Arthritis Rheum , vol.54 , pp. 2793-2806
    • Cohen, S.B.1    Emery, P.2    Greenwald, M.W.3    Dougados, M.4    Furie, R.A.5
  • 58
    • 39049142995 scopus 로고    scopus 로고
    • B-cell depletion with rituximab in relapsing-remitting multiple sclerosis
    • doi: 10.1056/NEJMoa0706383
    • Hauser SL, Waubant E, Arnold DL, Vollmer T, Antel J, et al. (2008) B-cell depletion with rituximab in relapsing-remitting multiple sclerosis. N Engl J Med 358: 676-688. doi:10.1056/NEJMoa0706383. PubMed: 18272891.
    • (2008) N Engl J Med , vol.358 , pp. 676-688
    • Hauser, S.L.1    Waubant, E.2    Arnold, D.L.3    Vollmer, T.4    Antel, J.5
  • 59
    • 41849116363 scopus 로고    scopus 로고
    • Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial
    • doi: 10.1002/ana.21363
    • Bar-Or A, Calabresi PA, Arnold D, Markowitz C, Shafer S, et al. (2008) Rituximab in relapsing-remitting multiple sclerosis: a 72-week, open-label, phase I trial. Ann Neurol 63: 395-400. doi:10.1002/ana.21363. PubMed: 18383069.
    • (2008) Ann Neurol , vol.63 , pp. 395-400
    • Bar-Or, A.1    Calabresi, P.A.2    Arnold, D.3    Markowitz, C.4    Shafer, S.5
  • 60
    • 70449480577 scopus 로고    scopus 로고
    • Rituximab, B-lymphocyte depletion, and preservation of beta-cell function
    • doi: 10.1056/NEJMoa0904452
    • Pescovitz MD, Greenbaum CJ, Krause-Steinrauf H, Becker DJ, Gitelman SE, et al. (2009) Rituximab, B-lymphocyte depletion, and preservation of beta-cell function. N Engl J Med 361: 2143-2152. doi:10.1056/NEJMoa0904452. PubMed: 19940299.
    • (2009) N Engl J Med , vol.361 , pp. 2143-2152
    • Pescovitz, M.D.1    Greenbaum, C.J.2    Krause-Steinrauf, H.3    Becker, D.J.4    Gitelman, S.E.5


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