Structural significance of galectin design: Impairment of homodimer stability by linker insertion and partial reversion by ligand presence

Protein Engineering, Design and Selection

Volumn 28, Issue 7, 2015, Pages 199-210

  Vértesy, Sabine ^a   Michalak, Malwina ^b   Miller, Michelle C ^c   Schnölzer, Martina ^d   André, Sabine ^a   Kopitz, Jürgen ^b   Mayo, Kevin H ^c   Gabius, Hans Joachim ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c UNIVERSITY OF MINNESOTA   (United States)

^d GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

Author keywords

hemagglutination; in source decay; lectin; sugar code

Indexed keywords

ANTIGEN-ANTIBODY REACTIONS; BINDING SITES; CARBOHYDRATES; CHEMICAL STABILITY; LIGANDS; MASS SPECTROMETRY; QUANTUM THEORY;

CARBOHYDRATE-RECOGNITION DOMAINS; HEMAGGLUTINATION; HETERONUCLEAR SINGLE-QUANTUM COHERENCES; IN-SOURCE DECAYS; INTERFACIAL CONTACT; LECTIN; SIGNAL INTENSITIES; WILD-TYPE PROTEINS;

PROTEINS;

CARBOHYDRATE; GALECTIN 1; HOMODIMER; LIGAND; NITROGEN 15; PROTEIN VARIANT;

AMINO ACID SEQUENCE; ARTICLE; BINDING SITE; COMPARATIVE STUDY; GEL FILTRATION; HEMAGGLUTINATION; HETERONUCLEAR SINGLE QUANTUM COHERENCE; HUMAN; MASS SPECTROMETRY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; NEUTRON SCATTERING; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTON NUCLEAR MAGNETIC RESONANCE; TANDEM REPEAT; WILD TYPE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROCEDURES; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; PROTEIN QUATERNARY STRUCTURE; PROTEIN SECONDARY STRUCTURE; PROTEIN STABILITY;

AMINO ACID SEQUENCE; GALECTIN 1; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; PROTEIN MULTIMERIZATION; PROTEIN STABILITY; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; TANDEM REPEAT SEQUENCES;

EID: 84937422316     PISSN: 17410126     EISSN: 17410134     Source Type: Journal    
DOI: 10.1093/protein/gzv014     Document Type: Article

References (63)

1. Amano, M., Eriksson, H., Manning, J.C., Detjen, K.M., André, S., Nishimura, S.-I., Lehtiö, J. and Gabius, H.-J. (2012). FEBS J., 279, 4062-4080
2. André, S., Sanchez-Ruderisch, H., Nakagawa, H., et al. (2007). FEBS J., 274, 3233-3256
3. André, S., Wang, G.-N., Gabius, H.-J. and Murphy, P.V. (2014). Carbohydr. Res., 389, 25-38
4. Bättig, P., Saudan, P., Gunde, T. and Bachmann, M.F. (2004). Mol. Immunol., 41, 9-18
5. Bi, S., Earl, L.A., Jacobs, L. and Baum, L.G. (2008). J. Biol. Chem., 283, 12248-12258
6. Bidon, N., Brichory, F., Bourguet, P., Le Pennec, J.P. and Dazord, L. (2001). Int. J. Mol. Med., 8, 245-250
7. Chichili, V.P.R., Kumar, V. and Sivaraman, J. (2013). Protein Sci., 22, 153-167
8. Cludts, S., Decaestecker, C., Mahillon, V., et al. (2009). Anticancer Res., 29, 4933-4940
9. Cooper, D.N.W. (1997). Trends Glycosci. Glycotechnol., 9, 57-67
10. Cooper, D.N.W. (2002). Biochim. Biophys. Acta, 1572, 209-231
11. Cummings, R.D. (2009). Mol. Biosyst., 5, 1087-1104
12. Dawson, H., André, S., Karamitopoulou, E., Zlobec, I. and Gabius, H.-J. (2013). Anticancer Res., 33, 3053-3059
13. Delaglio, F., Grzesiek, S., Vuister, G.W., Zhu, G., Pfeifer, J. and Bax, A. (1995). J. Biomol. NMR, 6, 277-293
14. Earl, L.A., Bi, S. and Baum, L.G. (2011). Glycobiology, 21, 6-12
15. Ermakova, E., Miller, M.C., Nesmelova, I.V., et al. (2013). Glycobiology, 23, 508-523
16. Gabius, H.-J. (2001). Biochimie, 83, 659-666
17. Gabius, H.-J., Engelhardt, R., Cramer, F., Bätge, R. and Nagel, G.A. (1985). Cancer Res., 45, 253-257
18. Gabius, H.-J., Walzel, H., Joshi, S.S., Kruip, J., Kojima, S., Gerke, V., Kratzin, H. and Gabius, S. (1992). Anticancer Res., 12, 669-676
19. Gabius, H.-J., André, S., Jiménez-Barbero, J., Romero, A. and Solís, D. (2011). Trends Biochem. Sci., 36, 298-313
20. Gauhar, A., Shaykhalishahi, H., Gremer, L., Mirecka, E.A. and Hoyer, W. (2014). Protein Eng. Des. Sel., 27, 473-479
21. Gitt, M.A., Colnot, C., Poirier, F., Nani, K.J., Barondes, S.H. and Leffler, H. (1998). J. Biol. Chem., 273, 2954-2960
22. Giudicelli, V., Lutomski, D., Lévi-Strauss, M., Bladier, D., Joubert-Caron, R. and Caron, M. (1997). Glycobiology, 7, viii-x.
23. Goehler, A., André, S., Kaltner, H., Sauer, M., Gabius, H.-J. and Doose, S. (2010). Biophys. J., 98, 3044-3053
24. Goehler, A., Büchner, C., André, S., Doose, S., Kaltner, H. and Gabius, H.-J. (2012). Biochimie, 94, 2649-2655
25. Hadari, Y.R., Arbel-Goren, R., Levy, Y., Amsterdam, A., Alon, R., Zakut, R. and Zick, Y. (2000). J. Cell Sci., 113, 2385-2397
26. He, L., André, S., Siebert, H.C., Helmholz, H., Niemeyer, B. and Gabius, H.-J. (2003). Biophys. J., 85, 511-524
27. Honke, K. and Taniguchi, N. (2009). In Gabius, H.-J. (ed.), The Sugar Code: Fundamentals of Glycosciences. Wiley-VCH, Weinheim, pp. 385-401
28. Houzelstein, D., Gonçalves, I.R., Orth, A., Bonhomme, F. and Netter, P. (2008). Genetics, 178, 1533-1545
29. Johnson, B.A. and Blevins, R.A. (1994). J. Biomol. NMR, 4, 603-614
30. Kaltner, H. and Gabius, H.-J. (2012). Histol. Histopathol., 27, 397-416
31. Kaltner, H., Solís, D., André, S., Lensch, M., Manning, J.C., Mürnseer, M., Sáiz, J. L. and Gabius, H.-J. (2009). Biochemistry, 48, 4403-4416
32. Kasai, K.-i. and Hirabayashi, J. (1996). J. Biochem., 119, 1-8
33. Katzenmaier, E.-M., André, S., Kopitz, J. and Gabius, H.-J. (2014). Anticancer Res., 34, 5429-5438
34. Keeler, J. (2005). Understanding NMR Spectroscopy. J. Wiley & Sons, New York
35. Kopitz, J., Bergmann, M. and Gabius, H.-J. (2010). IUBMB Life, 62, 624-628
36. Kopitz, J., Ballikaya, S., André, S. and Gabius, H.-J. (2012). Neurochem. Res., 37, 1267-1276
37. Kopitz, J., Vértesy, S., André, S., Fiedler, S., Schnölzer, M. and Gabius, H.-J. (2014). Biochimie, 104, 90-99
38. Ledeen, R.W., Wu, G., André, S., Bleich, D., Huet, G., Kaltner, H., Kopitz, J. and Gabius, H.-J. (2012). Ann. NY Acad. Sci., 1253, 206-221
39. Levy, Y., Arbel-Goren, R., Hadari, Y.R., Eshhar, S., Ronen, D., Elhanany, E., Geiger, B. and Zick, Y. (2001). J. Biol. Chem., 276, 31285-31295
40. Levy, Y., Auslender, S., Eisenstein, M., Vidavski, R.R., Ronen, D., Bershadsky, A. D. and Zick, Y. (2006). Glycobiology, 16, 463-476
41. Lis, H. and Sharon, N. (1998). Chem. Rev., 98, 637-674
42. López-Lucendo, M.F., Solís, D., André, S., Hirabayashi, J., Kasai, K.-i., Kaltner, H., Gabius, H.-J. and Romero, A. (2004). J. Mol. Biol., 343, 957-970
43. Miller, M.C., Ribeiro, J.P., Roldós, V., et al. (2011). Glycobiology, 12, 1627-1641
44. Morris, S., Ahmad, N., André, S., Kaltner, H., Gabius, H.-J., Brenowitz, M. and Brewer, C.F. (2004). Glycobiology, 14, 293-300
45. Nagy, N., Legendre, H., Engels, O., et al. (2003). Cancer, 97, 1849-1858
46. Nesmelova, I.V., Pang, M., Baum, L.G. and Mayo, K.H. (2008). Biomol. NMR Assign., 2, 203-205
47. Nesmelova, I.V., Ermakova, E., Daragan, V.A., Pang, M., Menéndez, M., Lagartera, L., Solís, D., Baum, L.G. and Mayo, K.H. (2010). J. Mol. Biol., 397, 1209-1230
48. Nishi, N., Itoh, A., Fujiyama, A., Yoshida, N., Araya, S.-i., Hirashima, M., Shoji, H. and Nakamura, T. (2005). FEBS Lett., 579, 2058-2064
49. Pace, K.E. and Baum, L.G. (1997). Trends Glycosci. Glycotechnol., 9, 21-29
50. Patsos, G. and Corfield, A. (2009). In Gabius, H.-J. (ed.), The Sugar Code: Fundamentals of Glycosciences. Wiley-VCH, Weinheim, pp. 111-137
51. Remmelink, M., de Leval, L., Decaestecker, C., et al. (2011). Histopathology, 58, 543-556
52. Roseman, S. (2001). J. Biol. Chem., 276, 41527-41542
53. Ruiz, F.M., Scholz, B.A., Buzamet, E., Kopitz, J., André, S., Menéndez, M., Romero, A., Solís, D. and Gabius, H.-J. (2014). FEBS J., 281, 1446-1461
54. Sato, M., Nishi, N., Shoji, H., et al. (2002). Glycobiology, 12, 191-197
55. Smetana, K., Jr, André, S., Kaltner, H., Kopitz, J. and Gabius, H.-J. (2013). Expert Opin. Ther. Targets, 17, 379-392
56. Solís, D., Bovin, N.V., Davis, A.P., Jiménez-Barbero, J., Romero, A., Roy, R., Smetana, K., Jr and Gabius, H.-J. (2015). Biochim. Biophys. Acta, 1850, 186-235
57. Spiro, R.G. (2002). Glycobiology, 12, 43R-56R.
58. Tracey, B.M., Feizi, T., Abbott, W.M., Carruthers, R.A., Green, B.N. and Lawson, A.M. (1992). J. Biol. Chem., 267, 10342-10347
59. Tsai, C.-M., Guan, C.-H., Hsieh, H.W., Hsu, T.-L., Tu, Z., Wu, K.J., Lin, C.H. and Lin, K.I. (2011). J. Immunol., 187, 1643-1652
60. Whitney, P.L., Powell, J.T. and Sanford, G.L. (1986). Biochem. J., 238, 683-689
61. Yoshida, H., Yamashita, S., Teraoka, M., Itoh, A., Nakakita, S.-i., Nishi, N. and Kamitori, S. (2012). FEBS J., 279, 3937-3951
62. Zick, Y., Eisenstein, M., Goren, R.A., Hadari, Y.R., Levy, Y. and Ronen, D. (2004). Glycoconj. J., 19, 517-526
63. Zuber, C. and Roth, J. (2009). In Gabius, H.-J. (ed.), The Sugar Code: Fundamentals of Glycosciences. Wiley-VCH, Weinheim, pp. 87-110