If there is an evolutionary selection pressure for the high frequency of MBL2 polymorphisms, what is it?

Clinical and Experimental Immunology

Volumn 176, Issue 2, 2014, Pages 165-171

  Eisen, D P ^a,b   Osthoff, M ^a,b  

^a ROYAL MELBOURNE HOSPITAL   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Immune; Infection susceptibility; Mannose binding lectin; Polymorphism; Selection

Indexed keywords

COMPLEMENT COMPONENT C4; MANNOSE BINDING LECTIN; MANNOSE BINDING LECTIN 2;

ARTERIAL WALL THICKNESS; ARTICLE; ATHEROSCLEROSIS; BALANCING SELECTION; CARDIOVASCULAR MORTALITY; CHROMOSOME 10Q; COMMON CAROTID ARTERY; COMPLEMENT FIXATION; COMPLEMENT LECTIN PATHWAY; GENE FREQUENCY; GENE FUNCTION; GENE LINKAGE DISEQUILIBRIUM; GENE LOCATION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC DRIFT; GENETIC POLYMORPHISM; GENETIC SELECTION; GRAM NEGATIVE SEPSIS; HAPLOTYPE; HEART INFARCTION; HETEROZYGOSITY; HETEROZYGOTE; HUMAN; IMMUNOSELECTION; INNATE IMMUNITY; NATURAL SELECTION; NONHUMAN; PHAGOCYTOSIS; POPULATION GENETICS; POSITIVE SELECTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BLOOD LEVEL; PURIFYING SELECTION; REPERFUSION INJURY; SINGLE NUCLEOTIDE POLYMORPHISM; STRUCTURAL GENE; TUBERCULOSIS; TYPHOID FEVER;

IMMUNE; INFECTION SUSCEPTIBILITY; MANNOSE-BINDING LECTIN; POLYMORPHISM; SELECTION;

ATHEROSCLEROSIS; COMMUNICABLE DISEASES; GENE FREQUENCY; HAPLOTYPES; HUMANS; MANNOSE-BINDING LECTIN; MUTATION; POLYMORPHISM, GENETIC; SELECTION, GENETIC;

EID: 84897950746     PISSN: 00099104     EISSN: 13652249     Source Type: Journal    
DOI: 10.1111/cei.12241     Document Type: Article

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