Alteration of metabolomic profiles by titanium dioxide nanoparticles in human gingivitis model

Biomaterials

Volumn 57, Issue , 2015, Pages 33-40

  Garcia Contreras, Rene ^a,c   Sugimoto, Masahiro ^b   Umemura, Naoki ^c   Kaneko, Miku ^b   Hatakeyama, Yoko ^b   Soga, Tomoyoshi ^b   Tomita, Masaru ^b   Scougall Vilchis, Rogelio J ^a   Contreras Bulnes, Rosalia ^a   Nakajima, Hiroshi ^c   Sakagami, Hiroshi ^c  

^a UNIVERSIDAD AUTÓNOMA DEL ESTADO DE MÉXICO   (Mexico)

^b KEIO UNIVERSITY   (Japan)

^c MEIKAI UNIVERSITY SCHOOL OF DENTISTRY   (Japan)

Author keywords

Human gingival fibroblast; Inerleukin 1 ; Inflammation; Metabolomics; Titanium dioxide nanoparticle

Indexed keywords

CELL CULTURE; DENTAL COMPOSITES; DENTAL MATERIALS; FIBROBLASTS; METABOLISM; METABOLITES; NANOPARTICLES; OXIDE MINERALS; PATHOLOGY; RISK ASSESSMENT; TITANIUM DIOXIDE; TRANSMISSION ELECTRON MICROSCOPY; UREA;

GINGIVAL INFLAMMATIONS; HUMAN GINGIVAL FIBROBLASTS; INFLAMMATION; INTRACELLULAR CONCENTRATION; METABOLOMIC ANALYSIS; METABOLOMICS; PROTEIN EXPRESSIONS; THERAPEUTIC STRATEGY;

TIO2 NANOPARTICLES;

AMINO ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; GLUTATHIONE; INTERLEUKIN 1BETA; POLYAMINE; PROSTAGLANDIN E2; TITANIUM DIOXIDE NANOPARTICLE; NANOPARTICLE; TITANIUM; TITANIUM DIOXIDE;

ARTICLE; CELL METABOLISM; CELL VACUOLE; CONTROLLED STUDY; GINGIVITIS; HUMAN; HUMAN CELL; METABOLITE; METABOLOMICS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TRANSMISSION ELECTRON MICROSCOPY; UREA CYCLE; CELL CULTURE; CHEMICALLY INDUCED; CHILD; DRUG EFFECTS; FEMALE; FIBROBLAST; GINGIVA; IMMUNOLOGY; METABOLISM; METABOLOME; PATHOLOGY; SIGNAL TRANSDUCTION;

CELLS, CULTURED; CHILD; FEMALE; FIBROBLASTS; GINGIVA; GINGIVITIS; HUMANS; INTERLEUKIN-1BETA; METABOLOME; NANOPARTICLES; SIGNAL TRANSDUCTION; TITANIUM;

EID: 84928944403     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.03.059     Document Type: Article

References (37)

1. Yang P., Gai S., Lin J. Functionalized mesoporous silica materials for controlled drug delivery. Chem Soc Rev 2012, 41:3679-3698.
2. Youns M., Hoheisel J.D., Efferth T. Therapeutic and diagnostic applications of nanoparticles. Curr Drug Targets 2011, 12:357-365.
3. Zhang L., Gu F.X., Chan J.M., Wang A.Z., Langer R.S., Farokhzad O.C. Nanoparticles in medicine: therapeutic applications and developments. Clin Pharmacol Ther 2008, 83:761-769.
4. Chen T., Yan J., Li Y. Genotoxicity of titanium dioxide nanoparticles. J Food Drug Anal 2014, 22:95-104.
5. Garcia-Contreras R., Argueta-Figueroa L., Mejia-Rubalcava C., Jimenez-Martinez R., Cuevas-Guajardo S., Sanchez-Reyna P.A., et al. Perspectives for the use of silver nanoparticles in dental practice. Int Dent J 2011, 61:297-301.
6. Lucas K., Maes M. Molecular mechanisms underpinning laser printer and photocopier induced symptoms, including chronic fatigue syndrome and respiratory tract hyperresponsiveness: pharmacological treatment with cinnamon and hydrogen. Neuro Endocrinol Lett 2013, 34:723-737.
7. Wittmaack K. In search of the most relevant parameter for quantifying lung inflammatory response to nanoparticle exposure: particle number, surface area, or what?. Environ Health Perspect 2007, 115:187-194.
8. Cho W.S., Duffin R., Bradley M., Megson I.L., MacNee W., Lee J.K., et al. Predictive value of invitro assays depends on the mechanism of toxicity of metal oxide nanoparticles. Part Fibre Toxicol 2013, 10:55.
9. 2 nanoparticles on cytotoxic action of chemotherapeutic drugs against a human oral squamous cell carcinoma cell line. InVivo 2014, 28:209-215.
10. 2 nanoparticles in human gingival fibroblast. InVivo 2014, 28:217-222.
11. Kantoh K., Ono M., Nakamura Y., Nakamura Y., Hashimoto K., Sakagami H., et al. Hormetic and anti-radiation effects of tropolone-related compounds. InVivo 2010, 24:843-851.
12. Soga T., Baran R., Suematsu M., Ueno Y., Ikeda S., Sakurakawa T., et al. Differential metabolomics reveals ophthalmic acid as an oxidative stress biomarker indicating hepatic glutathione consumption. JBiol Chem 2006, 281:16768-16776.
13. Sugimoto M., Sakagami H., Yokote Y., Onuma H., Kaneko M., Mori M., et al. Non-targeted metabolite profiling in activated macrophage secretion. Metabolomics 2012, 8:624-633.
14. Sugimoto M., Wong D.T., Hirayama A., Soga T., Tomita M. Capillary electrophoresis mass spectrometry-based saliva metabolomics identified oral, breast and pancreatic cancer-specific profiles. Metabolomics 2010, 6:78-95.
15. Sugimoto M., Kawakami M., Robert M., Soga T., Tomita M. Bioinformatics tools for mass spectroscopy-based metabolomic data processing and analysis. Curr Bioinform 2012, 7:96-108.
16. Thurn K.T., Arora H., Paunesku T., Wu A., Brown E.M., Doty C., et al. Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells. Nanomedicine 2011, 7:123-130.
17. Sawada S., Chosa N., Ishisaki A., Naruishi K. Enhancement of gingival inflammation induced by synergism of IL-1β and IL-6. Biomed Res 2013, 34:31-40.
18. Rajshankar D., Downey G.P., McCulloch C.A. IL-1beta enhances cell adhesion to degraded fibronectin. Faseb J 2012, 26:4429-4444.
19. Zhang G., Li J., Purkayastha S., Tang Y., Zhang H., Yin Y., et al. Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH. Nature 2013, 497:211-216.
20. Yaplito-Lee J., Chow C.W., Boneh A. Histopathological findings in livers of patients with urea cycle disorders. Mol Genet Metab 2013, 108:161-165.
21. Lara A., Khatri S.B., Wang Z., Comhair S.A., Xu W., Dweik R.A., et al. Alterations of the arginine metabolome in asthma. Am J Respir Crit Care Med 2008, 178:673-681.
22. Roje S. S-Adenosyl-L-methionine: beyond the universal methyl group donor. Phytochemistry 2006, 67:1686-1698.
23. Holen E., Espe M., Andersen S.M., Taylor R., Aksnes A., Mengesha Z., et al. Aco culture approach show that polyamine turnover is affected during inflammation in Atlantic salmon immune and liver cells and that arginine and LPS exerts opposite effects on p38MAPK signaling. Fish Shellfish Immunol 2014, 37:286-298.
24. Bjelakovic G., Stojanovic I., Jevtovic Stoimenov T., Pavlovic D., Kocic G., Rossi S., et al. Metabolic correlations of glucocorticoids and polyamines in inflammation and apoptosis. Amino Acids 2010, 39:29-43.
25. Minois N. Molecular basis of the 'anti-aging' effect of spermidine and other natural polyamines - a mini-review. Gerontology 2014, 60:319-326.
26. Liu Q., Gross S.S. Binding sites of nitric oxide synthases. Methods Enzymol 1996, 268:311-324.
27. Ono M., Kantoh K., Ueki J., Shimada A., Wakabayashi H., Matsuta T., et al. Quest for anti-inflammatory substances using IL-1β-stimulated gingival fibroblasts. InVivo 2011, 25:763-768.
28. King A.L., Polhemus D.J., Bhushan S., Otsuka H., Kondo K., Nicholson C.K., et al. Hydrogen sulfide cytoprotective signaling is endothelial nitric oxide synthase-nitric oxide dependent. Proc Natl Acad Sci U S A 2014, 111:3182-3187.
29. Bhowmick R., Girotti A.W. Cytoprotective signaling associated with nitric oxide upregulation in tumor cells subjected to photodynamic therapy-like oxidative stress. Free Radic Bio Med 2013, 57:39-48.
30. Gut P., Verdin E. The nexus of chromatin regulation and intermediary metabolism. Nature 2013, 502:489-498.
31. Karbiner M.S., Sierra L., Minahk C., Fonio M.C., Bruno M.P., Jerez S. The role of oxidative stress in alterations of hematological parameters and inflammatory markers induced by early hypercholesterolemia. Life Sci 2013, 93:503-508.
32. Huang Y.Y., Xia M.Z., Wang H., Liu X.J., Hu Y.F., Chen Y.H., et al. Cadmium selectively induces MIP-2 and COX-2 through PTEN-mediated Akt activation in RAW264.7 cells. Toxicol Sci 2014, 138:310-321.
33. 2 nano particles induced hippocampal neuroinflammation in mice. PLoS One 2014 Mar 21, 9(3):e92230. eCollection 2014. PMID: 24658543. 10.1371/journal.pone.0092230.
34. Husain M., Saber A.T., Guo C., Jacobsen N.R., Jensen K.A., Yauk C.L., et al. Pulmonary instillation of low doses of titanium dioxide nanoparticles in mice leads to particle retention and gene expression changes in the absence of inflammation. Toxicol Appl Pharmacol 2013, 269(3):250-262.
35. Delgado-Buenrostro N.L., Medina-Reyes E.I., Lastres-Becker I., Freyre-Fonseca V., Ji Z., Hernández-Pando R., et al. Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: a positive regulator role of Nrf2 on cytokine release. Environ Toxicol 2014 Feb 26, [Epub ahead of print] PMID: 24615891. 10.1002/tox.21957.
36. Ratnasekhar C., Sonane M., Satish A., Mudiam M.K. Metabolomics reveals the perturbations in the metabolome of caenorhabditis elegans exposed to titanium dioxide nanoparticles. Nanotoxicology 2015 Feb 16, 1-11. [Epub ahead of print] PMID: 25683258.
37. Bo Y., Jin C., Liu Y., Yu W., Kang H. Metabolomic analysis on the toxicological effects of TiO[U+2082] nanoparticles in mouse fibroblast cells: from the perspective of perturbations in amino acid metabolism. Toxicol Mech Methods 2014, 24(7):461-469.