Pterostilbene inhibits triple-negative breast cancer metastasis via inducing microRNA-205 expression and negatively modulates epithelial-to-mesenchymal transition

Journal of Nutritional Biochemistry

Volumn 26, Issue 6, 2015, Pages 675-685

  Su, Chih Ming ^a,b   Lee, Wei Hwa ^b   Wu, Alexander T H ^c,d   Lin, Yen Kuang ^c   Wang, Liang Shun ^a,b   Wu, Chih Hsiung ^a,b   Yeh, Chi Tai ^a,b  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^d TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Epithelial to mesenchymal transition (EMT); Metastasis; MiR 205; Pterostilbene; Triple negative breast cancer

Indexed keywords

FOCAL ADHESION KINASE; MICRORNA 205; PROTEIN KINASE B; PROTEIN TYROSINE KINASE; PTEROSTILBENE; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR ZEB1; UVOMORULIN; VIMENTIN; CADHERIN; FOCAL ADHESION KINASE 1; HOMEODOMAIN PROTEIN; MICRORNA; MIRN205 MICRORNA, HUMAN; PTK2 PROTEIN, HUMAN; SMALL INTERFERING RNA; STILBENE DERIVATIVE; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER CELL LINE; BREAST CARCINOMA; BREAST METASTASIS; CELL INVASION; CELL MIGRATION; CLINICAL ARTICLE; CONTROLLED STUDY; DOWN REGULATION; DRUG MECHANISM; EPITHELIAL MESENCHYMAL TRANSITION; FEMALE; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HUMAN TISSUE; MCF 7 CELL LINE; METASTASIS INHIBITION; METASTASIS POTENTIAL; MOUSE; NOD SCID MOUSE; NONHUMAN; SIGNAL TRANSDUCTION; TRIPLE NEGATIVE BREAST CANCER; TUMOR INVASION; TUMOR XENOGRAFT; UPREGULATION; WESTERN BLOTTING; ANIMAL; DRUG EFFECTS; DRUG SCREENING; GENETICS; METABOLISM; NEOPLASM METASTASIS; NONOBESE DIABETIC MOUSE; SCID MOUSE; TUMOR CELL LINE;

GASTROPODA; MUS;

ANIMALS; CADHERINS; CELL LINE, TUMOR; DOWN-REGULATION; EPITHELIAL-MESENCHYMAL TRANSITION; FEMALE; FOCAL ADHESION KINASE 1; GENE EXPRESSION REGULATION, NEOPLASTIC; HOMEODOMAIN PROTEINS; HUMANS; MCF-7 CELLS; MICE; MICE, INBRED NOD; MICE, SCID; MICRORNAS; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; STILBENES; TRANSCRIPTION FACTORS; TRIPLE NEGATIVE BREAST NEOPLASMS; UP-REGULATION; VIMENTIN; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84928928498     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2015.01.005     Document Type: Article

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