Alpha-carotene inhibits metastasis in Lewis lung carcinoma in vitro, and suppresses lung metastasis and tumor growth in combination with taxol in tumor xenografted C57BL/6 mice

Journal of Nutritional Biochemistry

Volumn 26, Issue 6, 2015, Pages 607-615

  Liu, Yi Zhen ^a   Yang, Chih Min ^a   Chen, Jen Yin ^b,c   Liao, Junn Wang ^a   Hu, Miao Lin ^a  

^a NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

^b CHI MEI MEDICAL CENTER   (Taiwan)

^c CHIA NAN UNIVERSITY OF PHARMACY AND SCIENCE   (Taiwan)

Author keywords

Lewis lung carcinoma; Metastasis; Taxol; Carotene; Carotene

Indexed keywords

ALPHA CAROTENE; BETA CAROTENE; BETA1 INTEGRIN; FOCAL ADHESION KINASE; GELATINASE A; GELATINASE B; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PACLITAXEL; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; UROKINASE; ALPHA-CAROTENE; ANTINEOPLASTIC AGENT; CAROTENOID; FOCAL ADHESION KINASE 1; MMP2 PROTEIN, MOUSE; MMP9 PROTEIN, MOUSE; PTK2 PROTEIN, MOUSE; TIMP1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER ADJUVANT THERAPY; CANCER INHIBITION; CELL MIGRATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; ENZYME PHOSPHORYLATION; IN VITRO STUDY; LEWIS LUNG CARCINOMA CELL; LUNG METASTASIS; LUNG PARENCHYMA; MALE; METASTASIS INHIBITION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; PROTEIN FAMILY; TUMOR INVASION; TUMOR XENOGRAFT; ANIMAL; C57BL MOUSE; CARCINOMA, LEWIS LUNG; DRUG SCREENING; GENETICS; LUNG NEOPLASMS; METABOLISM;

ANIMALIA; MUS;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CARCINOMA, LEWIS LUNG; CAROTENOIDS; FOCAL ADHESION KINASE 1; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; MICE; MICE, INBRED C57BL; PACLITAXEL; PLASMINOGEN ACTIVATOR INHIBITOR 1; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; UROKINASE-TYPE PLASMINOGEN ACTIVATOR; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84928926834     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2014.12.012     Document Type: Article

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