Overweight and obesity in midlife and brain structure and dementia 26 years later

American Journal of Epidemiology

Volumn 181, Issue 9, 2015, Pages 672-679

  Albanese, Emiliano ^a   Davis, Benjamin ^a   Jonsson, Palmi V ^a   Chang, Milan ^a   Aspelund, Thor ^a   Garcia, Melissa ^a   Harris, Tamara ^a   Gudnason, Vilmundur ^a   Launer, Lenore J ^a  

^a NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

brain vascular lesions; cohort study; dementia; epidemiology; mortality; obesity

Indexed keywords

BODY MASS; BRAIN; COHORT ANALYSIS; DISEASE PREVALENCE; EPIDEMIOLOGY; MORTALITY; NUMERICAL MODEL; OBESITY; PATHOLOGY; WEIGHT;

ADULT; ARTICLE; BODY MASS; BRAIN DAMAGE; BRAIN HEMORRHAGE; BRAIN SIZE; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; DEMENTIA; DEMOGRAPHY; DISEASE ASSOCIATION; FEMALE; FOLLOW UP; HUMAN; LIFESTYLE; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; OBESITY; PREVALENCE; WHITE MATTER LESION; AGED; BRAIN; BRAIN INFARCTION; COMPLICATION; EPIDEMIOLOGY; ICELAND; MIDDLE AGED; MORTALITY; PATHOLOGY; VERY ELDERLY;

AGED; AGED, 80 AND OVER; BODY MASS INDEX; BRAIN; BRAIN INFARCTION; CEREBRAL HEMORRHAGE; DEMENTIA; FEMALE; FOLLOW-UP STUDIES; HUMANS; ICELAND; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OBESITY;

EID: 84928910829     PISSN: 00029262     EISSN: 14766256     Source Type: Journal    
DOI: 10.1093/aje/kwu331     Document Type: Article

References (41)

1. Prince M, Bryce R, Albanese E, et al. The global prevalence of dementia: a systematic review and metaanalysis. Alzheimers Dement. 2013;9(1):63-75.e2.
2. Daviglus ML, Bell CC, Berrettini W, et al. NIH state-of-thescience conference statement: preventing Alzheimers disease and cognitive decline. NIH Consens State Sci Statements. 2010; 27(4):1-30.
3. Finucane MM, Stevens GA, Cowan MJ, et al. National, regional, and global trends in body-mass index since 1980: systematic analysis of health examination surveys and epidemiological studies with 960 country-years and 9.1 million participants. Lancet. 2011;377(9765):557-567.
4. Luchsinger JA, Gustafson DR. Adiposity and Alzheimers disease. Curr Opin Clin Nutr Metab Care. 2009;12(1): 15-21.
5. JagustW. What can imaging reveal about obesity and the brain? Curr Alzheimer Res. 2007;4(2):135-139.
6. Jagust WJ, Zheng L, Harvey DJ, et al. Neuropathological basis of magnetic resonance images in aging and dementia. Ann Neurol. 2008;63(1):72-80.
7. Hassing LB, Dahl AK, Thorvaldsson V, et al. Overweight in midlife and risk of dementia: a 40-year follow-up study. Int J Obes (Lond). 2009;33(8):893-898.
8. Rosengren A, Skoog I, Gustafson D, et al. Body mass index, other cardiovascular risk factors, and hospitalization for dementia. Arch Intern Med. 2005;165(3):321-326.
9. Whitmer RA, Gunderson EP, Barrett-Connor E, et al. Obesity in middle age and future risk of dementia: a 27 year longitudinal population based study. BMJ. 2005;330(7504):1360.
10. Beydoun MA, Lhotsky A, Wang Y, et al. Association of adiposity status and changes in early to mid-Adulthood with incidence of Alzheimers disease. Am J Epidemiol. 2008; 168(10):1179-1189.
11. Fitzpatrick AL, Kuller LH, Lopez OL, et al. Midlife and late-life obesity and the risk of dementia: cardiovascular health study. Arch Neurol. 2009;66(3):336-342.
12. Gustafson DR, Backman K, Waern M, et al. Adiposity indicators and dementia over 32 years in Sweden. Neurology. 2009;73(19):1559-1566.
13. Kivipelto M, Ngandu T, Fratiglioni L, et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol. 2005;62(10):1556-1560.
14. Tolppanen AM, Ngandu T, Kareholt I, et al. Midlife and late-life body mass index and late-life dementia: results from a prospective population-based cohort. J Alzheimers Dis. 2014; 38(1):201-209.
15. Harris TB, Launer LJ, Eiriksdottir G, et al. Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol. 2007; 165(9):1076-1087.
16. Sigurdsson E, Thorgeirsson G, Sigvaldason H, et al. Prevalence of coronary heart disease in Icelandic men 1968-1986. The Reykjavik Study. Eur Heart J. 1993;14(5):584-591.
17. Sigurdsson S, Aspelund T, Forsberg L, et al. Brain tissue volumes in the general population of the elderly: the AGES-Reykjavik. Neuroimage. 2012;59(4):3862-3870.
18. Zijdenbos AP, Forghani R, Evans AC. Automatic pipeline analysis of 3-D MRI data for clinical trials: application to multiple sclerosis. IEEE Trans Med Imaging. 2002;21(10): 1280-1291.
19. Vidal JS, Sigurdsson S, Jonsdottir MK, et al. Coronary artery calcium, brain function and structure: the AGES-Reykjavik Study. Stroke. 2010;41(5):891-897.
20. Sveinbjornsdottir S, Sigurdsson S, Aspelund T, et al. Cerebral microbleeds in the population based AGES-Reykjavik: prevalence and location. J Neurol Neurosurg Psychiatry. 2008; 79(9):1002-1006.
21. Folstein MF, Folstein SE, McHugh PR. Mini-mental state. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975;12(3):189-198.
22. Weschler D, ed. Administration and Scoring Manual for the Weschler Adult Intelligence Scale-III. London, UK: Psychological Corporation; 2008.
23. Reitan RM, Wolfson D. The Halstead-Reitan Neuropsychological Test Battery: Theory and Clinical Interpretation. Tucson, AZ: Neuropsychology Press; 1993.
24. Rey A. Lexamen Clinique en Psychologie. Paris, France: Presses Universitaires de France; 1964.
25. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition.Washington, DC: American Psychiatric Association; 1994.
26. Debette S, Seshadri S, Beiser A, et al. Midlife vascular risk factor exposure accelerates structural brain aging and cognitive decline. Neurology. 2011;77(5):461-468.
27. Rose GA. The diagnosis of ischaemic heart pain and intermittent claudication in field surveys. Bull World Health Organ. 1962;27:645-658.
28. Yesavage JA, Brink TL, Rose TL, et al. Development and validation of a geriatric depression screening scale: a preliminary report. J Psychiatr Res. 1982;17(1):37-49.
29. Keller L, XuW,Wang HX, et al. The obesity related gene, FTO, interacts with APOE, and is associated with Alzheimers disease risk: a prospective cohort study. J Alzheimers Dis. 2011; 23(3):461-469.
30. Weuve J, Tchetgen Tchetgen EJ, Glymour MM, et al. Accounting for bias due to selective attrition: the example of smoking and cognitive decline. Epidemiology. 2012;23(1): 119-128.
31. Whitmer RA, Gustafson DR, Barrett-Connor E, et al. Central obesity and increased risk of dementia more than three decades later. Neurology. 2008;71(14):1057-1064.
32. Taylor RW, Keil D, Gold EJ, et al. Body mass index, waist girth, and waist-to-hip ratio as indexes of total and regional adiposity in women: evaluation using receiver operating characteristic curves. Am J Clin Nutr. 1998;67(1):44-49.
33. Driscoll I, Beydoun MA, An Y, et al. Midlife obesity and trajectories of brain volume changes in older adults. Hum Brain Mapp. 2012;33(9):2204-2210.
34. Anstey KJ, Cherbuin N, Budge M, et al. Body mass index in midlife and late-life as a risk factor for dementia: a metaanalysis of prospective studies. Obes Rev. 2011;12(5):e426-e437.
35. Whitmer RA, Gunderson EP, Quesenberry CP Jr, et al. Body mass index in midlife and risk of Alzheimer disease and vascular dementia. Curr Alzheimer Res. 2007;4(2):103-109.
36. Ho AJ, Stein JL, Hua X, et al. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly. Proc Natl Acad Sci U S A. 2010; 107(18):8404-8409.
37. Stewart R, Masaki K, Xue QL, et al. A 32-year prospective study of change in body weight and incident dementia: the Honolulu-Asia Aging Study. Arch Neurol. 2005;62(1):55-60.
38. Lieb W, Beiser AS, Vasan RS, et al. Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA. 2009;302(23):2565-2572.
39. Gustafson DR, Bäckman K, Lissner L, et al. Leptin and dementia over 32 years-The Prospective Population Study of Women. Alzheimers Dement. 2012;8(4):272-277.
40. Holden KF, Lindquist K, Tylavsky FA, et al. Serum leptin level and cognition in the elderly: findings from the Health ABC Study. Neurobiol Aging. 2009;30(9):1483-1489.
41. Corley J, Gow AJ, Starr JM, et al. Is body mass index in old age related to cognitive abilities? The Lothian Birth Cohort 1936 Study. Psychol Aging. 2010;25(4):867-875.