Small-molecule inhibitors of Staphylococcus aureus RnpA-mediated RNA turnover and tRNA processing

Antimicrobial Agents and Chemotherapy

Volumn 59, Issue 4, 2015, Pages 2016-2028

  Eidem, Tess M ^a,b   Lounsbury, Nicole ^c   Emery, John F ^b   Bulger, Jeffrey ^b   Smith, Andrew ^b   Abou Gharbia, Magid ^c   Childers, Wayne ^c   Dunman, Paul M ^b  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b UNIVERSITY OF ROCHESTER SCHOOL OF MEDICINE AND DENTISTRY   (United States)

^c TEMPLE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFECTIVE AGENT; RIBONUCLEASE; RIFAMPICIN; RNPA 1000; RNPA 2000; TRANSFER RNA; UNCLASSIFIED DRUG; BACTERIAL RNA; HYDRAZINE DERIVATIVE; MOLECULAR LIBRARY; RIBONUCLEASE P; RNPA2000; THIOUREA;

ACINETOBACTER BAUMANNII; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ANTIMICROBIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; ENTEROCOCCUS FAECIUM; ENZYME ACTIVITY; ENZYME SPECIFICITY; ESCHERICHIA COLI; GRAM NEGATIVE BACTERIUM; IN VITRO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; RNA DEGRADATION; RNA PROCESSING; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS PYOGENES; ANALOGS AND DERIVATIVES; ANTAGONISTS AND INHIBITORS; CELL LINE; CELL SURVIVAL; DRUG EFFECTS; GENETIC TRANSCRIPTION; HIGH THROUGHPUT SCREENING; HUMAN; METABOLISM; MICROBIAL SENSITIVITY TEST; MOLECULAR LIBRARY;

ANTI-BACTERIAL AGENTS; CELL LINE; CELL SURVIVAL; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; HYDRAZINES; MICROBIAL SENSITIVITY TESTS; RIBONUCLEASE P; RNA, BACTERIAL; RNA, TRANSFER; SMALL MOLECULE LIBRARIES; STAPHYLOCOCCUS AUREUS; THIOUREA; TRANSCRIPTION, GENETIC;

EID: 84928889242     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.04352-14     Document Type: Article

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