Inactivation of phospholipase D diminishes Acinetobacter baumannii pathogenesis

Infection and Immunity

Volumn 78, Issue 5, 2010, Pages 1952-1962

  Jacobs, Anna C ^a   Hood, Indriati ^b   Boyd, Kelli L ^c   Olson, Patrick D ^a   Morrison, John M ^a   Carson, Steven ^a   Sayood, Khalid ^d   Iwen, Peter C ^a   Skaar, Eric P ^b   Dunman, Paul M ^a  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

^d UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOLIPASE D;

ACINETOBACTER BAUMANNII; ANIMAL TISSUE; ARTICLE; BACTEREMIA; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ISOLATE; CELL INVASION; EPITHELIUM CELL; GENETIC VARIABILITY; HUMAN; MUTANT; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; TRANSPOSON;

ACINETOBACTER BAUMANNII; ACINETOBACTER INFECTIONS; AMINO ACID SEQUENCE; ANIMAL STRUCTURES; ANIMALS; BACTERIAL PROTEINS; COLONY COUNT, MICROBIAL; DNA TRANSPOSABLE ELEMENTS; EPITHELIAL CELLS; HISTOCYTOCHEMISTRY; HUMANS; MICE; MICE, INBRED C57BL; MICROSCOPY; MOLECULAR SEQUENCE DATA; MUTAGENESIS, INSERTIONAL; PHOSPHOLIPASE D; PNEUMONIA, BACTERIAL; SERUM; VIRULENCE; VIRULENCE FACTORS;

EID: 77951222464     PISSN: 00199567     EISSN: 10985522     Source Type: Journal    
DOI: 10.1128/IAI.00889-09     Document Type: Article

References (44)

1. Batey, R. G. 1986. Pathogenesis of caseous lymphadenitis in sheep and goats. Aust. Vet. J. 63:269-272.
2. Chen, M. Z., P. R. Hsueh, L. N. Lee, C. J. Yu, P. C. Yang, and K. T. Luh. 2001. Severe community-acquired pneumonia due to Acinetobacter baumannii. Chest 120:1072-1077.
3. Cheng, Z. F., Y. Zuo, Z. Li, K. E. Rudd, and M. P. Deutscher. 1998. The vacB gene required for virulence in Shigella flexneri and Escherichia coli encodes the exoribonuclease RNase R. J. Biol. Chem. 273:14077-14080.
4. Choi, C. H., J. S. Lee, Y. C. Lee, T. I. Park, and J. C. Lee. 2008. Acinetobacter baumannii invades epithelial cells and outer membrane protein A mediates interactions with epithelial cells. BMC Microbiol. 8:216.
5. Cianciotto, N. P. 2005. Type II secretion: a protein secretion system for all seasons. Trends Microbiol. 13:581-588. (Pubitemid 41661339)
6. Dijkshoorn, L., A. Nemec, and H. Seifert. 2007. An increasing threat in hospitals: multidrug-resistant Acinetobacter baumannii. Nat. Rev. Microbiol. 5:939-951.
7. Doi, Y., S. Husain, B. A. Potoski, K. R. McCurry, and D. L. Paterson. 2009. Extensively drug-resistant Acinetobacter baumannii. Emerg. Infect. Dis. 15: 980-982.
8. Edwards, J. L., D. D. Entz, and M. A. Apicella. 2003. Gonococcal phospholipase D modulates the expression and function of complement receptor 3 in primary cervical epithelial cells. Infect. Immun. 71:6381-6391.
9. Erova, T. E., V. G. Kosykh, A. A. Fadl, J. Sha, A. J. Horneman, and A. K. Chopra. 2008. Cold shock exoribonuclease R (VacB) is involved in Aeromonas hydrophila pathogenesis. J. Bacteriol. 190:3467-3474.
10. Getchell-White, S. I., L. G. Donowitz, and D. H. Groschel. 1989. The inanimate environment of an intensive care unit as a potential source of nosocomial bacteria: evidence for long survival of Acinetobacter calcoaceticus. Infect. Control Hosp. Epidemiol. 10:402-407.
11. Gouby, A., M. J. Carles-Nurit, N. Bouziges, G. Bourg, R. Mesnard, and P. J. Bouvet. 1992. Use of pulsed-field gel electrophoresis for investigation of hospital outbreaks of Acinetobacter baumannii. J. Clin. Microbiol. 30:1588-1591.
12. Hirai, Y. 1991. Survival of bacteria under dry conditions; from a viewpoint of nosocomial infection. J. Hosp. Infect. 19:191-200.
13. Hodgson, A. L., P. Bird, and I. T. Nisbet. 1990. Cloning, nucleotide sequence, and expression in Escherichia coli of the phospholipase D gene from Corynebacterium pseudotuberculosis. J. Bacteriol. 172:1256-1261.
14. Hodgson, A. L., K. Carter, M. Tachedjian, J. Krywult, L. A. Corner, M. McColl, and A. Cameron. 1999. Efficacy of an ovine caseous lymphadenitis vaccine formulated using a genetically inactive form of the Corynebacterium pseudotuberculosis phospholipase D. Vaccine 17:802-808.
15. Hunger, M., R. Schmucker, V. Kishan, and W. Hillen. 1990. Analysis and nucleotide sequence of an origin of DNA replication in Acinetobacter calcoaceticus and its use for Escherichia coli shuttle plasmids. Gene 87:45-51.
16. King, L. B., E. Swiatlo, A. Swiatlo, and L. S. McDaniel. 2009. Serum resistance and biofilm formation in clinical isolates of Acinetobacter baumannii. FEMS Immunol. Med. Microbiol. 55:414-421.
17. Koonin, E. V. 1996. A duplicated catalytic motif in a new superfamily of phosphohydrolases and phospholipid synthases that includes poxvirus envelope proteins. Trends Biochem. Sci. 21:242-243.
18. Kwon, K. T., W. S. Oh, J. H. Song, H. H. Chang, S. I. Jung, S. W. Kim, S. Y. Ryu, S. T. Heo, D. S. Jung, J. Y. Rhee, S. Y. Shin, K. S. Ko, K. R. Peck, and N. Y. Lee. 2007. Impact of imipenem resistance on mortality in patients with Acinetobacter bacteraemia. J. Antimicrob. Chemother. 59:525-530.
19. Lam, S. M., and T. Y. Huang. 1997. Acinetobacter pericarditis with tamponade in a patient with systemic lupus erythematosus. Lupus 6:480-483.
20. Loehfelm, T. W., N. R. Luke, and A. A. Campagnari. 2008. Identification and characterization of an Acinetobacter baumannii biofilm-associated protein. J. Bacteriol. 190:1036-1044.
21. Maegele, M., S. Gregor, E. Steinhausen, B. Bouillon, M. M. Heiss, W. Perbix, F. Wappler, D. Rixen, J. Geisen, B. Berger-Schreck, and R. Schwarz. 2005. The long-distance tertiary air transfer and care of tsunami victims: injury pattern and microbiological and psychological aspects. Crit. Care Med. 33:1136-1140.
22. Mancilla-Ramirez, J., C. A. Dinarello, and J. I. Santos-Preciado. 1995. Phosphatidylcholine induces an increase in the production of interleukin-6 and improves survival of rats with neonatal sepsis caused by Klebsiella pneumoniae. Gac. Med. Mex. 131:14-22.
23. McKean, S. C., J. K. Davies, and R. J. Moore. 2007. Expression of phospholipase D, the major virulence factor of Corynebacterium pseudotuberculosis, is regulated by multiple environmental factors and plays a role in macrophage death. Microbiology 153:2203-2211.
24. Moyed, H. S., and K. P. Bertrand. 1983. Mutations in multicopy Tn10 tet plasmids that confer resistance to inhibitory effects of inducers of tet gene expression. J. Bacteriol. 155:557-564.
25. Moyed, H. S., T. T. Nguyen, and K. P. Bertrand. 1983. Multicopy Tn10 tet plasmids confer sensitivity to induction of tet gene expression. J. Bacteriol. 155:549-556.
26. Musa, E. K., N. Desai, and M. W. Casewell. 1990. The survival of Acinetobacter calcoaceticus inoculated on fingertips and on formica. J. Hosp. Infect. 15:219-227.
27. Oncul, O., O. Keskin, H. V. Acar, Y. Kucukardali, R. Evrenkaya, E. M. Atasoyu, C. Top., S. Nalbant, S. Ozkan, G. Emekdas, S. Cavuslu, M. H. Us, A. Pahsa, and M. Gokben. 2002. Hospital-acquired infections following the 1999 Marmara earthquake. J. Hosp. Infect. 51:47-51.
28. Pitlick, F. A., and Y. Nemerson. 1976. Purification and characterization of tissue factor apoprotein. Methods Enzymol. 45:37-48.
29. Ponting, C. P., and I. D. Kerr. 1996. A novel family of phospholipase D homologues that includes phospholipid synthases and putative endonucleases: identification of duplicated repeats and potential active site residues. Protein Sci. 5:914-922.
30. Russo, T. A., U. MacDonald, J. M. Beanan, R. Olson, I. J. MacDonald, S. L. Sauberan, N. R. Luke, L. W. Schultz, and T. C. Umland. 2009. Penicillin-binding protein 7/8 contributes to the survival of Acinetobacter baumannii in vitro and in vivo. J. Infect. Dis. 199:513-521.
31. Scott, P. T., K. Petersen, J. Fishbain, D. W. Craft, A. J. Ewell, K. Moran, D. C. Hack, G. A. Deye, S. Riddell, G. Christopher, J. D. Mancuso, B. P. Petruccelli, T. Endy, L. Lindler, K. Davis, E. G. Milstrey, L. Brosch, J. Pool, C. L. Blankenship, C. J. Witt, J. L. Malone, D. N. Tornberg, A. Srinivasan, and the Centers for Disease Control and Prevention. 2004. Acinetobacter baumannii infections among patients at military medical facilities treating injured U.S. service members, 2002-2004. Morb. Mortal. Wkly. Rep. 53: 1063-1066.
32. Seifert, H., A. Strate, and G. Pulverer. 1995. Nosocomial bacteremia due to Acinetobacter baumannii. Clinical features, epidemiology, and predictors of mortality. Medicine (Baltimore) 74:340-349.
33. Siegel, R. E. 2008. Emerging gram-negative antibiotic resistance: daunting challenges, declining sensitivities, and dire consequences. Respir. Care 53: 471-479.
34. Soucek, A., C. Michalec, and A. Souckova. 1971. Identification and characterization of a new enzyme of the group "phospholipase D" isolated from Corynebacterium ovis. Biochim. Biophys. Acta 227:116-128.
35. Sunenshine, R. H., M. O. Wright, L. L. Maragakis, A. D. Harris, X. Song, J. Hebden, S. E. Cosgrove, A. Anderson, J. Carnell, D. B. Jernigan, D. G. Kleinbaum, T. M. Perl, H. C. Standiford, and A. Srinivasan. 2007. Multidrug-resistant Acinetobacter infection mortality rate and length of hospitalization. Emerg. Infect. Dis. 13:97-103.
36. Tomaras, A. P., C. W. Dorsey, R. E. Edelmann, and L. A. Actis. 2003. Attachment to and biofilm formation on abiotic surfaces by Acinetobacter baumannii: involvement of a novel chaperone-usher pili assembly system. Microbiology 149:3473-3484.
37. Tomkowski, W. Z., P. Kuca, R. Gralec, J. Burakowski, P. Caban, T. Orlowski, and M. Kurzyna. 2003. Management of purulent pericarditis. Monaldi Arch. Chest Dis. 59:308-309.
38. Tong, M. J. 1972. Septic complications of war wounds. JAMA 219:1044-1047.
39. Tsao, M. Y., T. L. Lin, P. F. Hsieh, and J. T. Wang. 2009. The 3′-to-5′ exoribonuclease (encoded by HP1248) of Helicobacter pylori regulates motility and apoptosis-inducing genes. J. Bacteriol. 191:2691-2702.
40. Valenzuela, M. S., E. V. Ikpeazu, and K. A. Siddiqui. 1996. E. coli growth inhibition by a high copy number derivative of plasmid pBR322. Biochem. Biophys. Res. Commun. 219:876-883.
41. Valenzuela, M. S., K. A. Siddiqui, and B. L. Sarkar. 1996. High expression of plasmid-encoded tetracycline resistance gene in E. coli causes a decrease in membrane-bound ATPase activity. Plasmid 36:19-25.
42. Wendt, C., B. Dietze, E. Dietz, and H. Ruden. 1997. Survival of Acinetobacter baumannii on dry surfaces. J. Clin. Microbiol. 35:1394-1397.
43. Wilderman, P. J., A. I. Vasil, Z. Johnson, and M. L. Vasil. 2001. Genetic and biochemical analyses of a eukaryotic-like phospholipase D of Pseudomonas aeruginosa suggest horizontal acquisition and a role for persistence in a chronic pulmonary infection model. Mol. Microbiol. 39:291-303.
44. Zaki, M. M. 1976. Relation between the toxogenicity and pyogenicity of Corynebacterium ovis in experimentally infected mice. Res. Vet. Sci. 20:197-200.