Glutaredoxin 2a overexpression in macrophages promotes mitochondrial dysfunction but has little or no effect on atherogenesis in LDL-receptor null mice

Atherosclerosis

Volumn 241, Issue 1, 2015, Pages 69-78

  Zamora, D A ^a   Downs, K P ^b   Ullevig, S L ^c   Tavakoli, S ^b   Kim, H S ^b   Qiao, M ^b   Greaves, D R ^e   Asmis, R ^b,d  

^a TRINITY UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c UNIVERSITY OF TEXAS AT SAN ANTONIO   (United States)

^d Mays Cancer Center at UT Health San Antonio   (United States)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Atherosclerosis; Glutaredoxin 2; Macrophage; Mitochondria; Reactive oxygen species; Thiols

Indexed keywords

ADENOSINE TRIPHOSPHATE; CHLORDANE; GLUTAREDOXIN; GLUTAREDOXIN 2A; HYBRID PROTEIN; LOW DENSITY LIPOPROTEIN RECEPTOR; MITOCHONDRIAL PROTEIN; OXYGEN; OXYSTEROL; UNCLASSIFIED DRUG; GLRX2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; BIOENERGY; CELL ISOLATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; ENZYME ACTIVITY; FEMALE; FLOW CYTOMETRY; FLUORESCENCE CONFOCAL MICROSCOPY; FLUORESCENCE MICROSCOPY; GENE OVEREXPRESSION; LIPID DIET; MALE; MITOCHONDRIAL MEMBRANE; MITOCHONDRIAL RESPIRATION; MITOCHONDRION; MONOCYTE; MONOCYTOSIS; MOUSE; NONHUMAN; OXYGEN CONSUMPTION; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; TRANSGENIC MOUSE; TURNOVER TIME; WESTERN BLOTTING; WILD TYPE; ANIMAL; AORTA; AORTA DISEASE; ATHEROSCLEROTIC PLAQUE; C57BL MOUSE; CELL CULTURE; DEFICIENCY; DISEASE MODEL; ENERGY METABOLISM; ENZYMOLOGY; GENETICS; KNOCKOUT MOUSE; METABOLISM; PATHOLOGY; SEVERITY OF ILLNESS INDEX;

ADENOSINE TRIPHOSPHATE; ANIMALS; AORTA; AORTIC DISEASES; APOPTOSIS; ATHEROSCLEROSIS; CELLS, CULTURED; DISEASE MODELS, ANIMAL; ENERGY METABOLISM; GLUTAREDOXINS; MACROPHAGES, PERITONEAL; MICE, INBRED C57BL; MICE, KNOCKOUT; MITOCHONDRIA; PLAQUE, ATHEROSCLEROTIC; RECEPTORS, LDL; SEVERITY OF ILLNESS INDEX;

EID: 84928882766     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2015.04.805     Document Type: Article

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