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Volumn 9, Issue 3, 2015, Pages

Infrared Fluorescent Imaging as a Potent Tool for In Vitro, Ex Vivo and In Vivo Models of Visceral Leishmaniasis

Author keywords

[No Author keywords available]

Indexed keywords

AMPHOTERICIN B; CARBACHOL; COMBRETASTATIN; DIMETHYL SULFOXIDE; HEAT SHOCK PROTEIN 70; HYGROMYCIN B; INDENOISOQUINOLINE; ISOQUINOLINE DERIVATIVE; OLIGONUCLEOTIDE; RED FLUORESCENT PROTEIN; RNA 18S; UNCLASSIFIED DRUG;

EID: 84928798956     PISSN: 19352727     EISSN: 19352735     Source Type: Journal    
DOI: 10.1371/journal.pntd.0003666     Document Type: Article
Times cited : (62)

References (47)
  • 3
    • 84892170478 scopus 로고    scopus 로고
    • Projects set to tackle neglected diseases
    • Hayden EC, (2014) Projects set to tackle neglected diseases. Nature 505: 142. doi: 10.1038/505142a 24402261
    • (2014) Nature , vol.505 , pp. 142
    • Hayden, E.C.1
  • 5
    • 84901266793 scopus 로고    scopus 로고
    • Strategies to overcome antileishmanial drugs unresponsiveness
    • Sundar S, Singh A, Singh OP, (2014) Strategies to overcome antileishmanial drugs unresponsiveness. J Trop Med 2014: 646932. doi: 10.1155/2014/646932 24876851
    • (2014) J Trop Med , vol.2014 , pp. 646932
    • Sundar, S.1    Singh, A.2    Singh, O.P.3
  • 6
    • 84922905992 scopus 로고    scopus 로고
    • Drug resistance in leishmaniasis: Newer developments
    • Mohapatra S, (2014) Drug resistance in leishmaniasis: Newer developments. Trop Parasitol 4: 4–9. doi: 10.4103/2229-5070.129142 24754020
    • (2014) Trop Parasitol , vol.4 , pp. 4-9
    • Mohapatra, S.1
  • 7
    • 81555207189 scopus 로고    scopus 로고
    • Development of vaccines against visceral leishmaniasis
    • Evans KJ, Kedzierski L, (2012) Development of vaccines against visceral leishmaniasis. J Trop Med 2012: 892817. doi: 10.1155/2012/892817 21912561
    • (2012) J Trop Med , vol.2012 , pp. 892817
    • Evans, K.J.1    Kedzierski, L.2
  • 8
    • 84916878714 scopus 로고    scopus 로고
    • Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf?
    • Reguera RM, Calvo-Álvarez E, Álvarez-Velilla R, Balaña-Fouce R, (2014) Target-based vs. phenotypic screenings in Leishmania drug discovery: A marriage of convenience or a dialogue of the deaf? Int J Parasitol Drugs Drug Resist 4: 355–357. doi: 10.1016/j.ijpddr.2014.05.001 25516847
    • (2014) Int J Parasitol Drugs Drug Resist , vol.4 , pp. 355-357
    • Reguera, R.M.1    Calvo-Álvarez, E.2    Álvarez-Velilla, R.3    Balaña-Fouce, R.4
  • 9
  • 10
    • 84863673241 scopus 로고    scopus 로고
    • An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages
    • Siqueira-Neto JL, Moon S, Jang J, Yang G, Lee C, et al. (2012) An image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophages. PLoS Negl Trop Dis 6: e1671. doi: 10.1371/journal.pntd.0001671 22720099
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. 1671
    • Siqueira-Neto, J.L.1    Moon, S.2    Jang, J.3    Yang, G.4    Lee, C.5
  • 11
    • 84874420362 scopus 로고    scopus 로고
    • A parasite rescue and transformation assay for antileishmanial screening against intracellular Leishmania donovani amastigotes in THP1 human acute monocytic leukemia cell line
    • Jain SK, Sahu R, Walker LA, Tekwani BL, . (2012) A parasite rescue and transformation assay for antileishmanial screening against intracellular Leishmania donovani amastigotes in THP1 human acute monocytic leukemia cell line. J Vis Exp. pii: 4054.
    • (2012) J Vis Exp. pii , pp. 4054
    • Jain, S.K.1    Sahu, R.2    Walker, L.A.3    Tekwani, B.L.4
  • 13
    • 12844263594 scopus 로고    scopus 로고
    • Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains
    • Saeij JP, Boyle JP, Grigg ME, Arrizabalaga G, Boothroyd JC, (2005) Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains. Infect Immun 73: 695–702. 15664907
    • (2005) Infect Immun , vol.73 , pp. 695-702
    • Saeij, J.P.1    Boyle, J.P.2    Grigg, M.E.3    Arrizabalaga, G.4    Boothroyd, J.C.5
  • 14
    • 34250643609 scopus 로고    scopus 로고
    • Real-time in vivo imaging of transgenic bioluminescent blood stages of rodent malaria parasites in mice
    • Franke-Fayard B, Waters AP, Janse CJ, (2006) Real-time in vivo imaging of transgenic bioluminescent blood stages of rodent malaria parasites in mice. Nat Protoc 1: 476–485. 17406270
    • (2006) Nat Protoc , vol.1 , pp. 476-485
    • Franke-Fayard, B.1    Waters, A.P.2    Janse, C.J.3
  • 15
    • 70449568251 scopus 로고    scopus 로고
    • Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination, which may hamper drug efficacy in sleeping sickness
    • Claes F, Vodnala SK, van Reet N, Boucher N, Lunden-Miguel H, et al. (2009) Bioluminescent imaging of Trypanosoma brucei shows preferential testis dissemination, which may hamper drug efficacy in sleeping sickness. PLoS Negl Trop Dis 3: e486. doi: 10.1371/journal.pntd.0000486 19621071
    • (2009) PLoS Negl Trop Dis , vol.3 , pp. 486
    • Claes, F.1    Vodnala, S.K.2    van Reet, N.3    Boucher, N.4    Lunden-Miguel, H.5
  • 16
    • 69449096246 scopus 로고    scopus 로고
    • Reporter genes facilitating discovery of drugs targeting protozoan parasites
    • Dube A, Gupta R, Singh N, (2009) Reporter genes facilitating discovery of drugs targeting protozoan parasites. Trends Parasitol 25: 432–439. doi: 10.1016/j.pt.2009.06.006 19720564
    • (2009) Trends Parasitol , vol.25 , pp. 432-439
    • Dube, A.1    Gupta, R.2    Singh, N.3
  • 17
    • 67650721251 scopus 로고    scopus 로고
    • Transgenic Leishmania donovani clinical isolates expressing green fluorescent protein constitutively for rapid and reliable ex vivo drug screening
    • Singh N, Gupta R, Jaiswal AK, Sundar S, Dube A, (2009) Transgenic Leishmania donovani clinical isolates expressing green fluorescent protein constitutively for rapid and reliable ex vivo drug screening. J Antimicrob Chemother 64: 370–374. doi: 10.1093/jac/dkp206 19525291
    • (2009) J Antimicrob Chemother , vol.64 , pp. 370-374
    • Singh, N.1    Gupta, R.2    Jaiswal, A.K.3    Sundar, S.4    Dube, A.5
  • 18
    • 84870750861 scopus 로고    scopus 로고
    • Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis
    • Calvo-Álvarez E, Guerrero NA, Alvarez-Velilla R, Prada CF, Requena JM, et al. (2012) Appraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasis. PLoS Negl Trop Dis 6: e1927. doi: 10.1371/journal.pntd.0001927 23209866
    • (2012) PLoS Negl Trop Dis , vol.6 , pp. 1927
    • Calvo-Álvarez, E.1    Guerrero, N.A.2    Alvarez-Velilla, R.3    Prada, C.F.4    Requena, J.M.5
  • 19
    • 84873740260 scopus 로고    scopus 로고
    • An alternative in vitro drug screening test using Leishmania amazonensis transfected with red fluorescent protein
    • Rocha MN, Corrêa CM, Melo MN, Beverley SM, Martins-Filho OA, et al. (2013) An alternative in vitro drug screening test using Leishmania amazonensis transfected with red fluorescent protein. Diagn Microbiol Infect Dis 75: 282–291. doi: 10.1016/j.diagmicrobio.2012.11.018 23312610
    • (2013) Diagn Microbiol Infect Dis , vol.75 , pp. 282-291
    • Rocha, M.N.1    Corrêa, C.M.2    Melo, M.N.3    Beverley, S.M.4    Martins-Filho, O.A.5
  • 21
    • 65649113981 scopus 로고    scopus 로고
    • Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome
    • Shu X, Royant A, Lin MZ, Aguilera TA, Lev-Ram V, et al. (2009) Mammalian expression of infrared fluorescent proteins engineered from a bacterial phytochrome. Science 324: 804–807. doi: 10.1126/science.1168683 19423828
    • (2009) Science , vol.324 , pp. 804-807
    • Shu, X.1    Royant, A.2    Lin, M.Z.3    Aguilera, T.A.4    Lev-Ram, V.5
  • 22
    • 79961182814 scopus 로고    scopus 로고
    • Bright and stable near-infrared fluorescent protein for in vivo imaging
    • Filonov GS, Piatkevich KD, Ting LM, Zhang J, Kim K, et al. (2012) Bright and stable near-infrared fluorescent protein for in vivo imaging. Nat Biotechnol 29: 757–761. doi: 10.1016/j.nbt.2012.03.002 22433081
    • (2012) Nat Biotechnol , vol.29 , pp. 757-761
    • Filonov, G.S.1    Piatkevich, K.D.2    Ting, L.M.3    Zhang, J.4    Kim, K.5
  • 23
    • 0030035450 scopus 로고    scopus 로고
    • The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3'-untranslated region
    • Charest H, Zhang WW, Matlashewski G, (1996) The developmental expression of Leishmania donovani A2 amastigote-specific genes is post-transcriptionally mediated and involves elements located in the 3'-untranslated region. J Biol Chem 271: 17081–17090. 8663340
    • (1996) J Biol Chem , vol.271 , pp. 17081-17090
    • Charest, H.1    Zhang, W.W.2    Matlashewski, G.3
  • 24
    • 0037205486 scopus 로고    scopus 로고
    • A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3'-untranslated region element
    • Boucher N, Wu Y, Dumas C, Dube M, Sereno D, et al. (2002) A common mechanism of stage-regulated gene expression in Leishmania mediated by a conserved 3'-untranslated region element. J Biol Chem 277: 19511–19520. 11912202
    • (2002) J Biol Chem , vol.277 , pp. 19511-19520
    • Boucher, N.1    Wu, Y.2    Dumas, C.3    Dube, M.4    Sereno, D.5
  • 25
    • 34548571854 scopus 로고    scopus 로고
    • Pitfalls of the CAT reporter gene for analyzing translational regulation in Leishmania
    • Folgueira C, Requena JM, (2007) Pitfalls of the CAT reporter gene for analyzing translational regulation in Leishmania. Parasitol Res 101: 1449–1452. 17676404
    • (2007) Parasitol Res , vol.101 , pp. 1449-1452
    • Folgueira, C.1    Requena, J.M.2
  • 27
    • 0031985666 scopus 로고    scopus 로고
    • Regional differences in the cellular immune response to experimental cutaneous or visceral infection with Leishmania donovani
    • Melby PC, Yang YZ, Cheng J, Zhao W, (1998) Regional differences in the cellular immune response to experimental cutaneous or visceral infection with Leishmania donovani. Infect Immun 66: 18–27. 9423834
    • (1998) Infect Immun , vol.66 , pp. 18-27
    • Melby, P.C.1    Yang, Y.Z.2    Cheng, J.3    Zhao, W.4
  • 28
    • 0022234330 scopus 로고
    • A limiting dilution assay for quantifying Leishmania major in tissues of infected mice
    • Titus RG, Marchand M, Boon T, Louis JA, (1985) A limiting dilution assay for quantifying Leishmania major in tissues of infected mice. Parasite Immunol 7: 545–555. 3877902
    • (1985) Parasite Immunol , vol.7 , pp. 545-555
    • Titus, R.G.1    Marchand, M.2    Boon, T.3    Louis, J.A.4
  • 29
    • 79952474741 scopus 로고    scopus 로고
    • Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system
    • Osorio Y, Travi BL, Renslo AR, Peniche AG, Melby PC, (2011) Identification of small molecule lead compounds for visceral leishmaniasis using a novel ex vivo splenic explant model system. PLoS Negl Trop Dis 5: e962. doi: 10.1371/journal.pntd.0000962 21358812
    • (2011) PLoS Negl Trop Dis , vol.5 , pp. 962
    • Osorio, Y.1    Travi, B.L.2    Renslo, A.R.3    Peniche, A.G.4    Melby, P.C.5
  • 30
  • 31
    • 0033003760 scopus 로고    scopus 로고
    • A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays
    • Zhang JH, Chung TD, Oldenburg KR, (1999) A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays. J Biomol Screen 4: 67–73. 10838414
    • (1999) J Biomol Screen , vol.4 , pp. 67-73
    • Zhang, J.H.1    Chung, T.D.2    Oldenburg, K.R.3
  • 32
    • 0034141801 scopus 로고    scopus 로고
    • Organ-specific immune responses associated with infectious disease
    • Engwerda CR, Kaye PM, (2000) Organ-specific immune responses associated with infectious disease. Immunol Today 21: 73–78. 10652464
    • (2000) Immunol Today , vol.21 , pp. 73-78
    • Engwerda, C.R.1    Kaye, P.M.2
  • 33
    • 79951722752 scopus 로고    scopus 로고
    • Fluorescent Leishmania species: development of stable GFP expression and its application for in vitro and in vivo studies
    • Bolhassani A, Taheri T, Taslimi Y, Zamanilui S, Zahedifard F, et al. (2011) Fluorescent Leishmania species: development of stable GFP expression and its application for in vitro and in vivo studies. Exp Parasitol 127: 637–645. doi: 10.1016/j.exppara.2010.12.006 21187086
    • (2011) Exp Parasitol , vol.127 , pp. 637-645
    • Bolhassani, A.1    Taheri, T.2    Taslimi, Y.3    Zamanilui, S.4    Zahedifard, F.5
  • 34
    • 77950330640 scopus 로고    scopus 로고
    • In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent
    • Seifert K, Escobar P, Croft SL, (2010) In vitro activity of anti-leishmanial drugs against Leishmania donovani is host cell dependent. J Antimicrob Chemother 65: 508–511. doi: 10.1093/jac/dkp500 20089542
    • (2010) J Antimicrob Chemother , vol.65 , pp. 508-511
    • Seifert, K.1    Escobar, P.2    Croft, S.L.3
  • 35
    • 14044270112 scopus 로고    scopus 로고
    • Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice
    • Lang T, Goyard S, Lebastard M, Milon G, (2005) Bioluminescent Leishmania expressing luciferase for rapid and high throughput screening of drugs acting on amastigote-harbouring macrophages and for quantitative real-time monitoring of parasitism features in living mice. Cell Microbiol 7: 383–392. 15679841
    • (2005) Cell Microbiol , vol.7 , pp. 383-392
    • Lang, T.1    Goyard, S.2    Lebastard, M.3    Milon, G.4
  • 36
    • 84879030428 scopus 로고    scopus 로고
    • Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay
    • De Rycker M, Hallyburton I, Thomas J, Campbell L, Wyllie S, et al. (2013) Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay. Antimicrob Agents Chemother 57: 2913–2922. doi: 10.1128/AAC.02398-12 23571538
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 2913-2922
    • De Rycker, M.1    Hallyburton, I.2    Thomas, J.3    Campbell, L.4    Wyllie, S.5
  • 37
    • 27444431869 scopus 로고    scopus 로고
    • The translational efficiencies of the two Leishmania infantum HSP70 mRNAs, differing in their 3'-untranslated regions, are affected by shifts in the temperature of growth through different mechanisms
    • Folgueira C, Quijada L, Soto M, Abanades DR, Alonso C, et al. (2005) The translational efficiencies of the two Leishmania infantum HSP70 mRNAs, differing in their 3'-untranslated regions, are affected by shifts in the temperature of growth through different mechanisms. J Biol Chem 280: 35172–35183. 16105831
    • (2005) J Biol Chem , vol.280 , pp. 35172-35183
    • Folgueira, C.1    Quijada, L.2    Soto, M.3    Abanades, D.R.4    Alonso, C.5
  • 38
    • 84857116769 scopus 로고    scopus 로고
    • Improvement of the green fluorescent protein reporter system in Leishmania spp. for the in vitro and in vivo screening of antileishmanial drugs
    • Pulido SA, Muñoz DL, Restrepo AM, Mesa CV, Alzate JF, et al. (2012) Improvement of the green fluorescent protein reporter system in Leishmania spp. for the in vitro and in vivo screening of antileishmanial drugs. Acta Trop 122: 36–45. doi: 10.1016/j.actatropica.2011.11.015 22155571
    • (2012) Acta Trop , vol.122 , pp. 36-45
    • Pulido, S.A.1    Muñoz, D.L.2    Restrepo, A.M.3    Mesa, C.V.4    Alzate, J.F.5
  • 39
    • 0242693036 scopus 로고    scopus 로고
    • Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes
    • Miβlitz A, Mottram JC, Overath P, Aebischer T, (2000) Targeted integration into a rRNA locus results in uniform and high level expression of transgenes in Leishmania amastigotes. Mol Biochem Parasitol 107: 251–261. 10779601
    • (2000) Mol Biochem Parasitol , vol.107 , pp. 251-261
    • Miβlitz, A.1    Mottram, J.C.2    Overath, P.3    Aebischer, T.4
  • 40
    • 57349131657 scopus 로고    scopus 로고
    • Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery
    • Mehta SR, Huang R, Yang M, Zhang XQ, Kolli B, et al. (2008) Real-time in vivo green fluorescent protein imaging of a murine leishmaniasis model as a new tool for Leishmania vaccine and drug discovery. Clin Vaccine Immunol 15: 1764–1770. doi: 10.1128/CVI.00270-08 18945882
    • (2008) Clin Vaccine Immunol , vol.15 , pp. 1764-1770
    • Mehta, S.R.1    Huang, R.2    Yang, M.3    Zhang, X.Q.4    Kolli, B.5
  • 41
    • 77956249998 scopus 로고    scopus 로고
    • Imaging of the host/parasite interplay in cutaneous leishmaniasis
    • Millington OR, Myburgh E, Mottram JC, Alexander J, (2010) Imaging of the host/parasite interplay in cutaneous leishmaniasis. Exp Parasitol 126: 310–317. doi: 10.1016/j.exppara.2010.05.014 20501336
    • (2010) Exp Parasitol , vol.126 , pp. 310-317
    • Millington, O.R.1    Myburgh, E.2    Mottram, J.C.3    Alexander, J.4
  • 42
    • 0033747235 scopus 로고    scopus 로고
    • Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models
    • Roy G, Dumas C, Sereno D, Wu Y, Singh AK, et al. (2000) Episomal and stable expression of the luciferase reporter gene for quantifying Leishmania spp. infections in macrophages and in animal models. Mol Biochem Parasitol 110: 195–206. 11071276
    • (2000) Mol Biochem Parasitol , vol.110 , pp. 195-206
    • Roy, G.1    Dumas, C.2    Sereno, D.3    Wu, Y.4    Singh, A.K.5
  • 43
    • 79959248739 scopus 로고    scopus 로고
    • Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation
    • Pescher P, Blisnick T, Bastin P, Späth GF, (2011) Quantitative proteome profiling informs on phenotypic traits that adapt Leishmania donovani for axenic and intracellular proliferation. Cell Microbiol 13: 978–991. doi: 10.1111/j.1462-5822.2011.01593.x 21501362
    • (2011) Cell Microbiol , vol.13 , pp. 978-991
    • Pescher, P.1    Blisnick, T.2    Bastin, P.3    Späth, G.F.4
  • 44
    • 0022907570 scopus 로고
    • In vitro screens in the experimental chemotherapy of leishmaniasis and trypanosomiasis
    • Croft SL, (1986) In vitro screens in the experimental chemotherapy of leishmaniasis and trypanosomiasis. Parasitol Today 2: 64–69. 15462773
    • (1986) Parasitol Today , vol.2 , pp. 64-69
    • Croft, S.L.1
  • 45
    • 0036167883 scopus 로고    scopus 로고
    • Pharmacokinetics, excretion and mass balance of liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate in humans
    • Bekersky I, Fielding RM, Dressler DE, Lee JW, Buell DN, et al. (2002) Pharmacokinetics, excretion and mass balance of liposomal amphotericin B (AmBisome) and amphotericin B deoxycholate in humans. Antimicrob Agents Chemother 46: 828–833. 11850268
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 828-833
    • Bekersky, I.1    Fielding, R.M.2    Dressler, D.E.3    Lee, J.W.4    Buell, D.N.5
  • 46
    • 84884259768 scopus 로고    scopus 로고
    • Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex
    • Mohamed-Ahmed AH, Seifert K, Yardley V, Burrell-Saward H, Brocchini S, et al. (2013) Antileishmanial activity, uptake, and biodistribution of an amphotericin B and poly(α-Glutamic Acid) complex. Antimicrob Agents Chemother 57: 4608–4614. doi: 10.1128/AAC.02343-12 23796924
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 4608-4614
    • Mohamed-Ahmed, A.H.1    Seifert, K.2    Yardley, V.3    Burrell-Saward, H.4    Brocchini, S.5
  • 47
    • 0017720537 scopus 로고
    • Regulation of Leishmania populations within the host. I. The variable course of Leishmania donovani infections in mice
    • Bradley DJ, Kirkley J, (1977) Regulation of Leishmania populations within the host. I. The variable course of Leishmania donovani infections in mice. Clin Exp Immunol 30: 119–129. 606433
    • (1977) Clin Exp Immunol , vol.30 , pp. 119-129
    • Bradley, D.J.1    Kirkley, J.2


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