Tensor GSVD of patient- and platform- matched tumor and normal DNA Copy- number profiles uncovers chromosome arm- wide patterns of tumor-exclusive platform- consistent alterations encoding for cell transformation and predicting ovarian cancer survival

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Sankaranarayanan, Preethi ^a,b   Schomay, Theodore E ^a,b   Aiello, Katherine A ^a,b   Alter, Orly ^a,b,c  

^a UNIVERSITY OF UTAH   (United States)

^b University of Utah   (United States)

^c UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; MESSENGER RNA; MICRORNA; MITOGEN ACTIVATED PROTEIN KINASE 14; TUMOR PROTEIN;

ARTICLE; BCAP31 GENE; CANCER STAGING; CANCER SURVIVAL; CDKN1A GENE; CELL IMMORTALIZATION; CELL TRANSFORMATION; CELLULAR IMMUNITY; CHROMOSOME ARM; CONTROLLED STUDY; COPY NUMBER ALTERATION; DECOMPOSITION; FEMALE; GENE AMPLIFICATION; GENE DELETION; GENE DOSAGE; GENERALIZED SINGULAR VALUE DECOMPOSITION; HUMAN; HUMAN CELL; MAPK14 GENE; ONCOGENE K RAS; OVARY CANCER; PABPC5 GENE; PATHOGENESIS; POLD2 GENE; PROTEIN EXPRESSION; RAD51AP1 GENE; RPA3 GENE; BIOSYNTHESIS; CHROMOSOMAL MAPPING; CHROMOSOME; COPY NUMBER VARIATION; CYSTADENOCARCINOMA, SEROUS; GENE EXPRESSION REGULATION; GENETICS; MUTATION; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PATHOLOGY; PROGNOSIS; SURVIVAL ANALYSIS; THEORETICAL MODEL;

CELL TRANSFORMATION, NEOPLASTIC; CHROMOSOME MAPPING; CHROMOSOMES; CYSTADENOCARCINOMA, SEROUS; DNA COPY NUMBER VARIATIONS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MICRORNAS; MODELS, THEORETICAL; MUTATION; NEOPLASM PROTEINS; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS; PROGNOSIS; RNA, MESSENGER; SURVIVAL ANALYSIS;

EID: 84928781250     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0121396     Document Type: Article

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