-
1
-
-
2142810973
-
Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure
-
Ahmed F, Brown KM, Stephan DA, Morrison JC, Johnson EC, Tomarev SI. 2004. Microarray analysis of changes in mRNA levels in the rat retina after experimental elevation of intraocular pressure. Invest Ophthalmol Vis Sci 45: 1247-1258.
-
(2004)
Invest Ophthalmol Vis Sci
, vol.45
, pp. 1247-1258
-
-
Ahmed, F.1
Brown, K.M.2
Stephan, D.A.3
Morrison, J.C.4
Johnson, E.C.5
Tomarev, S.I.6
-
2
-
-
33748780095
-
Role of complement in neurodegeneration and neuroinflammation
-
Bonifati DM, Kishore U. 2007. Role of complement in neurodegeneration and neuroinflammation. Mol Immunol 44: 999-1010.
-
(2007)
Mol Immunol
, vol.44
, pp. 999-1010
-
-
Bonifati, D.M.1
Kishore, U.2
-
3
-
-
78751489896
-
Early microglia activation in a mouse model of chronic glaucoma
-
Bosco A, Steele MR, Vetter ML. 2011. Early microglia activation in a mouse model of chronic glaucoma. J Comp Neurol 519: 599-620.
-
(2011)
J Comp Neurol
, vol.519
, pp. 599-620
-
-
Bosco, A.1
Steele, M.R.2
Vetter, M.L.3
-
4
-
-
84865605323
-
Early reduction of microglia activation by irradiation in a model of chronic glaucoma
-
Bosco A, Crish SD, Steele MR, Romero CO, Inman DM, Horner PJ, Calkins DJ, Vetter ML. 2012. Early reduction of microglia activation by irradiation in a model of chronic glaucoma. PLoS ONE 7: e43602.
-
(2012)
Plos ONE
, vol.7
-
-
Bosco, A.1
Crish, S.D.2
Steele, M.R.3
Romero, C.O.4
Inman, D.M.5
Horner, P.J.6
Calkins, D.J.7
Vetter, M.L.8
-
5
-
-
80052798328
-
A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucoma
-
Burgoyne CF. 2011. A biomechanical paradigm for axonal insult within the optic nerve head in aging and glaucoma. Exp Eye Res 93: 120-132.
-
(2011)
Exp Eye Res
, vol.93
, pp. 120-132
-
-
Burgoyne, C.F.1
-
6
-
-
2142713917
-
Analysis of leukocyte extravasation across the blood-brain barrier: Conceptual and technical aspects
-
Callahan MK, Ransohoff RM. 2004. Analysis of leukocyte extravasation across the blood-brain barrier: Conceptual and technical aspects. Curr Allergy Asthma Rep 4: 65-73.
-
(2004)
Curr Allergy Asthma Rep
, vol.4
, pp. 65-73
-
-
Callahan, M.K.1
Ransohoff, R.M.2
-
7
-
-
33748743268
-
CNS immune privilege: Hiding in plain sight
-
Carson MJ, Doose JM, Melchior B, Schmid CD, Ploix CC. 2006. CNS immune privilege: Hiding in plain sight. Immunol Rev 213: 48-65.
-
(2006)
Immunol Rev
, vol.213
, pp. 48-65
-
-
Carson, M.J.1
Doose, J.M.2
Melchior, B.3
Schmid, C.D.4
Ploix, C.C.5
-
8
-
-
77954884148
-
Neural injury following stroke: Are Toll-like receptors the link between the immune system and the CNS?
-
Downes CE, Crack PJ. 2010. Neural injury following stroke: Are Toll-like receptors the link between the immune system and the CNS? Br J Pharmacol 160: 1872-1888.
-
(2010)
Br J Pharmacol
, vol.160
, pp. 1872-1888
-
-
Downes, C.E.1
Crack, P.J.2
-
9
-
-
79955943750
-
Microglial activation in the visual pathway in experimental glaucoma: Spatiotemporal characterization and correlation with axonal injury
-
Ebneter A, Casson RJ, Wood JP, Chidlow G. 2010. Microglial activation in the visual pathway in experimental glaucoma: Spatiotemporal characterization and correlation with axonal injury. Invest Ophthalmol Vis Sci 51: 6448-6460.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 6448-6460
-
-
Ebneter, A.1
Casson, R.J.2
Wood, J.P.3
Chidlow, G.4
-
10
-
-
33847099936
-
Astrocytes are active players in cerebral innate immunity
-
Farina C, Aloisi F, Meinl E. 2007. Astrocytes are active players in cerebral innate immunity. Trends Immunol 28: 138-145.
-
(2007)
Trends Immunol
, vol.28
, pp. 138-145
-
-
Farina, C.1
Aloisi, F.2
Meinl, E.3
-
11
-
-
67649786938
-
Influence of the mannose receptor in host immune responses
-
Gazi U, Martinez-Pomares L. 2009. Influence of the mannose receptor in host immune responses. Immunobiology 214: 554-561.
-
(2009)
Immunobiology
, vol.214
, pp. 554-561
-
-
Gazi, U.1
Martinez-Pomares, L.2
-
12
-
-
78149360132
-
Fate mapping analysis reveals that adult microglia derive from primitive macrophages
-
Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, Mehler MF, Conway SJ, Ng LG, Stanley ER, et al. 2010. Fate mapping analysis reveals that adult microglia derive from primitive macrophages. Science 330: 841-845.
-
(2010)
Science
, vol.330
, pp. 841-845
-
-
Ginhoux, F.1
Greter, M.2
Leboeuf, M.3
Nandi, S.4
See, P.5
Gokhan, S.6
Mehler, M.F.7
Conway, S.J.8
Ng, L.G.9
Stanley, E.R.10
-
13
-
-
77950363010
-
Mechanisms underlying inflammation in neurodegeneration
-
Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. 2010. Mechanisms underlying inflammation in neurodegeneration. Cell 140: 918-934.
-
(2010)
Cell
, vol.140
, pp. 918-934
-
-
Glass, C.K.1
Saijo, K.2
Winner, B.3
Marchetto, M.C.4
Gage, F.H.5
-
14
-
-
61449250853
-
Astrocytes are very sensitive to develop innate immune responses to lipid-carried short interfering RNA
-
Gorina R, Santalucia T, Petegnief V, Ejarque-Ortiz A, Saura J, Planas AM. 2009. Astrocytes are very sensitive to develop innate immune responses to lipid-carried short interfering RNA. Glia 57: 93-107.
-
(2009)
Glia
, vol.57
, pp. 93-107
-
-
Gorina, R.1
Santalucia, T.2
Petegnief, V.3
Ejarque-Ortiz, A.4
Saura, J.5
Planas, A.M.6
-
15
-
-
84874365204
-
Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina
-
Gramlich OW, Beck S, Thun Hohenstein-Blaul N, Boehm N, Ziegler A, Vetter JM, Pfeiffer N, Grus FH. 2013. Enhanced insight into the autoimmune component of glaucoma: IgG autoantibody accumulation and pro-inflammatory conditions in human glaucomatous retina. PloS ONE 8: e57557.
-
(2013)
Plos ONE
, vol.8
-
-
Gramlich, O.W.1
Beck, S.2
Thun Hohenstein-Blaul, N.3
Boehm, N.4
Ziegler, A.5
Vetter, J.M.6
Pfeiffer, N.7
Grus, F.H.8
-
16
-
-
79953166049
-
Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death
-
Gregory MS, Hackett CG, Abernathy EF, Lee KS, Saff RR, Hohlbaum AM, Moody KS, Hobson MW, Jones A, Kolovou P, et al. 2011. Opposing roles for membrane bound and soluble Fas ligand in glaucoma-associated retinal ganglion cell death. PLoS ONE 6: e17659.
-
(2011)
Plos ONE
, vol.6
-
-
Gregory, M.S.1
Hackett, C.G.2
Abernathy, E.F.3
Lee, K.S.4
Saff, R.R.5
Hohlbaum, A.M.6
Moody, K.S.7
Hobson, M.W.8
Jones, A.9
Kolovou, P.10
-
17
-
-
0025021550
-
Changes in the extracellular matrix of the human optic nerve head in primary open-angle glaucoma
-
Hernandez MR, Andrzejewska WM, Neufeld AH. 1990. Changes in the extracellular matrix of the human optic nerve head in primary open-angle glaucoma. Am J Ophthalmol 109: 180-188.
-
(1990)
Am J Ophthalmol
, vol.109
, pp. 180-188
-
-
Hernandez, M.R.1
Rzejewska, W.M.2
Neufeld, A.H.3
-
18
-
-
0028136393
-
Collagen type IV gene expression in human optic nerve heads with primary open angle glaucoma
-
Hernandez MR, Ye H, Roy S. 1994. Collagen type IV gene expression in human optic nerve heads with primary open angle glaucoma. Exp Eye Res 59: 41-51.
-
(1994)
Exp Eye Res
, vol.59
, pp. 41-51
-
-
Hernandez, M.R.1
Ye, H.2
Roy, S.3
-
19
-
-
53049094645
-
Astrocytes in glaucomatous optic neuropathy
-
Hernandez MR, Miao H, Lukas T. 2008. Astrocytes in glaucomatous optic neuropathy. Prog Brain Res 173: 353-373.
-
(2008)
Prog Brain Res
, vol.173
, pp. 353-373
-
-
Hernandez, M.R.1
Miao, H.2
Lukas, T.3
-
20
-
-
49049091210
-
STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury
-
Herrmann JE, Imura T, Song B, Qi J, Ao Y, Nguyen TK, Korsak RA, Takeda K, Akira S, Sofroniew MV. 2008. STAT3 is a critical regulator of astrogliosis and scar formation after spinal cord injury. J Neurosci 28: 7231-7243.
-
(2008)
J Neurosci
, vol.28
, pp. 7231-7243
-
-
Herrmann, J.E.1
Imura, T.2
Song, B.3
Qi, J.4
Ao, Y.5
Nguyen, T.K.6
Korsak, R.A.7
Takeda, K.8
Akira, S.9
Sofroniew, M.V.10
-
21
-
-
38049075806
-
Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma
-
Howell GR, Libby RT, Jakobs TC, Smith RS, Phalan FC, Barter JW, Barbay JM, Marchant JK, Mahesh N, Porciatti V, et al. 2007. Axons of retinal ganglion cells are insulted in the optic nerve early in DBA/2J glaucoma. J Cell Biol 179: 1523-1537.
-
(2007)
J Cell Biol
, vol.179
, pp. 1523-1537
-
-
Howell, G.R.1
Libby, R.T.2
Jakobs, T.C.3
Smith, R.S.4
Phalan, F.C.5
Barter, J.W.6
Barbay, J.M.7
Marchant, J.K.8
Mahesh, N.9
Porciatti, V.10
-
22
-
-
79953297488
-
Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma
-
Howell GR, Macalinao DG, Sousa GL, Walden M, Soto I, Kneeland SC, Barbay JM, King BL, Marchant JK, Hibbs M, et al. 2011a. Molecular clustering identifies complement and endothelin induction as early events in a mouse model of glaucoma. J Clin Invest 121: 1429-1444.
-
(2011)
J Clin Invest
, vol.121
, pp. 1429-1444
-
-
Howell, G.R.1
Macalinao, D.G.2
Sousa, G.L.3
Walden, M.4
Soto, I.5
Kneeland, S.C.6
Barbay, J.M.7
King, B.L.8
Marchant, J.K.9
Hibbs, M.10
-
23
-
-
80052038055
-
Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data
-
Howell GR, Walton DO, King BL, Libby RT, John SW. 2011b. Datgan, a reusable software system for facile interrogation and visualization of complex transcription profiling data. BMC Genomics 12: 429.
-
(2011)
BMC Genomics
, vol.12
, pp. 429
-
-
Howell, G.R.1
Walton, D.O.2
King, B.L.3
Libby, R.T.4
John, S.W.5
-
24
-
-
84859726329
-
Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma
-
Howell GR, Soto I, Zhu X, Ryan M, Macalinao DG, Sousa GL, Caddle LB, MacNicoll KH, Barbay JM, Porciatti V, et al. 2012. Radiation treatment inhibits monocyte entry into the optic nerve head and prevents neuronal damage in a mouse model of glaucoma. J Clin Invest 122: 1246-1261.
-
(2012)
J Clin Invest
, vol.122
, pp. 1246-1261
-
-
Howell, G.R.1
Soto, I.2
Zhu, X.3
Ryan, M.4
Macalinao, D.G.5
Sousa, G.L.6
Caddle, L.B.7
Macnicoll, K.H.8
Barbay, J.M.9
Porciatti, V.10
-
25
-
-
84879429446
-
Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice
-
Howell GR, Soto I, Ryan M, Graham LC, Smith RS, John SW. 2013. Deficiency of complement component 5 ameliorates glaucoma in DBA/2J mice. J Neuroinflammation 10: 76.
-
(2013)
J Neuroinflammation
, vol.10
, pp. 76
-
-
Howell, G.R.1
Soto, I.2
Ryan, M.3
Graham, L.C.4
Smith, R.S.5
John, S.W.6
-
26
-
-
0036847848
-
Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system
-
Husemann J, Loike JD, Anankov R, Febbraio M, Silverstein SC. 2002. Scavenger receptors in neurobiology and neuropathology: Their role on microglia and other cells of the nervous system. Glia 40: 195-205.
-
(2002)
Glia
, vol.40
, pp. 195-205
-
-
Husemann, J.1
Loike, J.D.2
Anankov, R.3
Febbraio, M.4
Silverstein, S.C.5
-
27
-
-
35548969443
-
Glial regulation of the cerebral microvasculature
-
Iadecola C, Nedergaard M. 2007. Glial regulation of the cerebral microvasculature. Nat Neurosci 10: 1369-1376.
-
(2007)
Nat Neurosci
, vol.10
, pp. 1369-1376
-
-
Iadecola, C.1
Nedergaard, M.2
-
28
-
-
39749173780
-
The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells
-
Ifergan I, Kebir H, Bernard M, Wosik K, Dodelet-Devillers A, Cayrol R, Arbour N, Prat A. 2008. The blood-brain barrier induces differentiation of migrating monocytes into Th17-polarizing dendritic cells. Brain 131: 785-799.
-
(2008)
Brain
, vol.131
, pp. 785-799
-
-
Ifergan, I.1
Kebir, H.2
Bernard, M.3
Wosik, K.4
Dodelet-Devillers, A.5
Cayrol, R.6
Arbour, N.7
Prat, A.8
-
29
-
-
34250171784
-
Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma
-
Inman DM, Horner PJ. 2007. Reactive nonproliferative gliosis predominates in a chronic mouse model of glaucoma. Glia 55: 942-953.
-
(2007)
Glia
, vol.55
, pp. 942-953
-
-
Inman, D.M.1
Horner, P.J.2
-
30
-
-
27544480984
-
Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice
-
Jakobs TC, Libby RT, Ben Y, John SWM, Masland RH. 2005. Retinal ganglion cell degeneration is topological but not cell type specific in DBA/2J mice. J Cell Biol 171: 313-325.
-
(2005)
J Cell Biol
, vol.171
, pp. 313-325
-
-
Jakobs, T.C.1
Libby, R.T.2
Ben, Y.3
John, S.4
Masland, R.H.5
-
32
-
-
80051950043
-
Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma
-
Jha P, Banda H, Tytarenko R, Bora PS, Bora NS. 2011. Complement mediated apoptosis leads to the loss of retinal ganglion cells in animal model of glaucoma. Mol Immunol 48: 2151-2158.
-
(2011)
Mol Immunol
, vol.48
, pp. 2151-2158
-
-
Jha, P.1
Banda, H.2
Tytarenko, R.3
Bora, P.S.4
Bora, N.S.5
-
33
-
-
0033950441
-
Chronology of optic nerve head and retinal responses to elevated intraocular pressure
-
Johnson EC, Deppmeier LM, Wentzien SK, Hsu I, Morrison JC. 2000. Chronology of optic nerve head and retinal responses to elevated intraocular pressure. Invest Ophthalmol Vis Sci 41: 431-442.
-
(2000)
Invest Ophthalmol Vis Sci
, vol.41
, pp. 431-442
-
-
Johnson, E.C.1
Deppmeier, L.M.2
Wentzien, S.K.3
Hsu, I.4
Morrison, J.C.5
-
34
-
-
79952264754
-
Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma
-
Johnson EC, Doser TA, Cepurna WA, Dyck JA, Jia L, Guo Y, Lambert WS, Morrison JC. 2011. Cell proliferation and interleukin-6-type cytokine signaling are implicated by gene expression responses in early optic nerve head injury in rat glaucoma. Invest Ophthalmol Vis Sci 52: 504-518.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 504-518
-
-
Johnson, E.C.1
Doser, T.A.2
Cepurna, W.A.3
Dyck, J.A.4
Jia, L.5
Guo, Y.6
Lambert, W.S.7
Morrison, J.C.8
-
35
-
-
34548070301
-
Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model
-
Johnson EC, Jia L, Cepurna WA, Doser TA, Morrison JC. 2007. Global changes in optic nerve head gene expression after exposure to elevated intraocular pressure in a rat glaucoma model. Invest Ophthalmol Vis Sci 48: 3161-3177.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 3161-3177
-
-
Johnson, E.C.1
Jia, L.2
Cepurna, W.A.3
Doser, T.A.4
Morrison, J.C.5
-
36
-
-
68249100026
-
Friend or foe? Resolving the impact of glial responses in glaucoma
-
Johnson EC, Morrison JC. 2009. Friend or foe? Resolving the impact of glial responses in glaucoma. J Glaucoma 18: 341-353.
-
(2009)
J Glaucoma
, vol.18
, pp. 341-353
-
-
Johnson, E.C.1
Morrison, J.C.2
-
37
-
-
65549153845
-
C-type lectins and phagocytosis
-
Kerrigan AM, Brown GD. 2009. C-type lectins and phagocytosis. Immunobiology 214: 562-575.
-
(2009)
Immunobiology
, vol.214
, pp. 562-575
-
-
Kerrigan, A.M.1
Brown, G.D.2
-
38
-
-
54049094029
-
Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension
-
Kompass KS, Agapova OA, Li W, Kaufman PL, Rasmussen CA, Hernandez MR. 2008. Bioinformatic and statistical analysis of the optic nerve head in a primate model of ocular hypertension. BMC Neurosci 9: 93.
-
(2008)
BMC Neurosci
, vol.9
, pp. 93
-
-
Kompass, K.S.1
Agapova, O.A.2
Li, W.3
Kaufman, P.L.4
Rasmussen, C.A.5
Hernandez, M.R.6
-
39
-
-
41149118513
-
How dying cells alert the immune system to danger
-
Kono H, Rock KL. 2008. How dying cells alert the immune system to danger. Nat Rev Immunol 8: 279-289.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 279-289
-
-
Kono, H.1
Rock, K.L.2
-
40
-
-
33745121143
-
Retinal synthesis and deposition of complement components induced by ocular hypertension
-
Kuehn MH, Kim CY, Ostojic J, Bellin M, Alward WL, Stone EM, Sakaguchi DS, Grozdanic SD, Kwon YH. 2006. Retinal synthesis and deposition of complement components induced by ocular hypertension. Exp Eye Res 83: 620-628.
-
(2006)
Exp Eye Res
, vol.83
, pp. 620-628
-
-
Kuehn, M.H.1
Kim, C.Y.2
Ostojic, J.3
Bellin, M.4
Alward, W.L.5
Stone, E.M.6
Sakaguchi, D.S.7
Grozdanic, S.D.8
Kwon, Y.H.9
-
41
-
-
48749128086
-
Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion
-
Kuehn MH, Kim CY, Jiang B, Dumitrescu AV, Kwon YH. 2008. Disruption of the complement cascade delays retinal ganglion cell death following retinal ischemia-reperfusion. Exp Eye Res 87: 89-95.
-
(2008)
Exp Eye Res
, vol.87
, pp. 89-95
-
-
Kuehn, M.H.1
Kim, C.Y.2
Jiang, B.3
Dumitrescu, A.V.4
Kwon, Y.H.5
-
42
-
-
84876784407
-
Innate immunity in the CNS: Redefining the relationship between the CNS and its environment
-
Lampron A, Elali A, Rivest S. 2013. Innate immunity in the CNS: Redefining the relationship between the CNS and its environment. Neuron 78: 214-232.
-
(2013)
Neuron
, vol.78
, pp. 214-232
-
-
Lampron, A.1
Elali, A.2
Rivest, S.3
-
43
-
-
75849151435
-
Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptormediated neuronal injury
-
Lehnardt S. 2010. Innate immunity and neuroinflammation in the CNS: The role of microglia in Toll-like receptormediated neuronal injury. Glia 58: 253-263.
-
(2010)
Glia
, vol.58
, pp. 253-263
-
-
Lehnardt, S.1
-
44
-
-
78149489635
-
Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling
-
Luo C, Yang X, Kain AD, Powell DW, Kuehn MH, Tezel G. 2010. Glaucomatous tissue stress and the regulation of immune response through glial Toll-like receptor signaling. Invest Ophthalmol Vis Sci 51: 5697-5707.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 5697-5707
-
-
Luo, C.1
Yang, X.2
Kain, A.D.3
Powell, D.W.4
Kuehn, M.H.5
Tezel, G.6
-
46
-
-
67650502739
-
Tenascin-C is an endogenous activator of Toll-like recep-tor 4 that is essential for maintaining inflammation in arthritic joint disease
-
Midwood K, Sacre S, Piccinini AM, Inglis J, Trebaul A, Chan E, Drexler S, Sofat N, Kashiwagi M, Orend G, et al. 2009. Tenascin-C is an endogenous activator of Toll-like recep-tor 4 that is essential for maintaining inflammation in arthritic joint disease. Nat Med 15: 774-780.
-
(2009)
Nat Med
, vol.15
, pp. 774-780
-
-
Midwood, K.1
Sacre, S.2
Piccinini, A.M.3
Inglis, J.4
Trebaul, A.5
Chan, E.6
Drexler, S.7
Sofat, N.8
Kashiwagi, M.9
Orend, G.10
-
48
-
-
33845413598
-
Tumor necrosis factor-a mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma
-
Nakazawa T, Nakazawa C, Matsubara A, Noda K, Hisatomi T, She H, Michaud N, Hafezi-Moghadam A, Miller JW, Benowitz LI. 2006. Tumor necrosis factor-a mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma. J Neurosci 26: 12633-12641.
-
(2006)
J Neurosci
, vol.26
, pp. 12633-12641
-
-
Nakazawa, T.1
Nakazawa, C.2
Matsubara, A.3
Noda, K.4
Hisatomi, T.5
She, H.6
Michaud, N.7
Hafezi-Moghadam, A.8
Miller, J.W.9
Benowitz, L.I.10
-
49
-
-
0032809910
-
Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma
-
Neufeld AH. 1999. Microglia in the optic nerve head and the region of parapapillary chorioretinal atrophy in glaucoma. Arch Ophthalmol 117: 1050-1056.
-
(1999)
Arch Ophthalmol
, vol.117
, pp. 1050-1056
-
-
Neufeld, A.H.1
-
50
-
-
84862640900
-
Under pressure: Cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy
-
Nickells RW, Howell GR, Soto I, John SW. 2012. Under pressure: Cellular and molecular responses during glaucoma, a common neurodegeneration with axonopathy. Annu Rev Neurosci 35: 153-179.
-
(2012)
Annu Rev Neurosci
, vol.35
, pp. 153-179
-
-
Nickells, R.W.1
Howell, G.R.2
Soto, I.3
John, S.W.4
-
51
-
-
68049149097
-
Network analysis of human glaucomatous optic nerve head astrocytes
-
Nikolskaya T, Nikolsky Y, Serebryiskaya T, Zvereva S, Sviridov E, Dezso Z, Rahkmatulin E, Brennan RJ, Yankovsky N, Bhattacharya SK, et al. 2009. Network analysis of human glaucomatous optic nerve head astrocytes. BMC Med Genomics 2: 24.
-
(2009)
BMC Med Genomics
, vol.2
, pp. 24
-
-
Nikolskaya, T.1
Nikolsky, Y.2
Serebryiskaya, T.3
Zvereva, S.4
Sviridov, E.5
Dezso, Z.6
Rahkmatulin, E.7
Brennan, R.J.8
Yankovsky, N.9
Bhattacharya, S.K.10
-
52
-
-
33745919498
-
Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury
-
Okada S, Nakamura M, Katoh H, Miyao T, Shimazaki T, Ishii K, Yamane J, Yoshimura A, Iwamoto Y, Toyama Y, et al. 2006. Conditional ablation of Stat3 or Socs3 discloses a dual role for reactive astrocytes after spinal cord injury. Nat Med 12: 829-834.
-
(2006)
Nat Med
, vol.12
, pp. 829-834
-
-
Okada, S.1
Nakamura, M.2
Katoh, H.3
Miyao, T.4
Shimazaki, T.5
Ishii, K.6
Yamane, J.7
Yoshimura, A.8
Iwamoto, Y.9
Toyama, Y.10
-
53
-
-
77951248779
-
Gene expression changes in areas of focal loss of retinal ganglion cells in the retina of DBA/2J mice
-
Panagis L, Zhao X, Ge Y, Ren L, Mittag TW, Danias J. 2010. Gene expression changes in areas of focal loss of retinal ganglion cells in the retina of DBA/2J mice. Invest Ophthalmol Vis Sci 51: 2024-2034.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 2024-2034
-
-
Panagis, L.1
Zhao, X.2
Ge, Y.3
Ren, L.4
Mittag, T.W.5
Danias, J.6
-
54
-
-
34547823399
-
Activity-dependent regulation of energy metabolism by astrocytes: An update
-
Pellerin L, Bouzier-Sore AK, Aubert A, Serres S, Merle M, Costalat R, Magistretti PJ. 2007. Activity-dependent regulation of energy metabolism by astrocytes: An update. Glia 55: 1251-1262.
-
(2007)
Glia
, vol.55
, pp. 1251-1262
-
-
Pellerin, L.1
Bouzier-Sore, A.K.2
Aubert, A.3
Serres, S.4
Merle, M.5
Costalat, R.6
Magistretti, P.J.7
-
55
-
-
0033013032
-
Enhanced tenascin expression associated with reactive astrocytes in human optic nerve heads with primary open angle glaucoma
-
Pena JD, Varela HJ, Ricard CS, Hernandez MR. 1999. Enhanced tenascin expression associated with reactive astrocytes in human optic nerve heads with primary open angle glaucoma. Exp Eye Res 68: 29-40.
-
(1999)
Exp Eye Res
, vol.68
, pp. 29-40
-
-
Pena, J.D.1
Varela, H.J.2
Ricard, C.S.3
Hernandez, M.R.4
-
56
-
-
0037083641
-
Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: Critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric Gi-linked receptors
-
Piccio L, Rossi B, Scarpini E, Laudanna C, Giagulli C, Issekutz AC, Vestweber D, Butcher EC, Constantin G. 2002. Molecular mechanisms involved in lymphocyte recruitment in inflamed brain microvessels: Critical roles for P-selectin glycoprotein ligand-1 and heterotrimeric Gi-linked receptors. J Immunol 168: 1940-1949.
-
(2002)
J Immunol
, vol.168
, pp. 1940-1949
-
-
Piccio, L.1
Rossi, B.2
Scarpini, E.3
Laudanna, C.4
Giagulli, C.5
Issekutz, A.C.6
Vestweber, D.7
Butcher, E.C.8
Constantin, G.9
-
57
-
-
84879513218
-
The time course of gene expression during reactive gliosis in the optic nerve
-
Qu J, Jakobs TC. 2013. The time course of gene expression during reactive gliosis in the optic nerve. PloS ONE 8: e67094.
-
(2013)
Plos ONE
, vol.8
-
-
Qu, J.1
Jakobs, T.C.2
-
58
-
-
0027399771
-
Open-angle glaucoma
-
Quigley HA. 1993. Open-angle glaucoma. New Engl J Med 328: 1097-1106.
-
(1993)
New Engl J Med
, vol.328
, pp. 1097-1106
-
-
Quigley, H.A.1
-
60
-
-
84859717206
-
Innate immunity in the central nervous system
-
Ransohoff RM, Brown MA. 2012. Innate immunity in the central nervous system. J Clin Invest 122: 1164-1171.
-
(2012)
J Clin Invest
, vol.122
, pp. 1164-1171
-
-
Ransohoff, R.M.1
Brown, M.A.2
-
61
-
-
84866364390
-
The anatomical and cellular basis of immune surveillance in the central nervous system
-
Ransohoff RM, Engelhardt B. 2012. The anatomical and cellular basis of immune surveillance in the central nervous system. Nat Rev Immunol 12: 623-635.
-
(2012)
Nat Rev Immunol
, vol.12
, pp. 623-635
-
-
Ransohoff, R.M.1
Engelhardt, B.2
-
62
-
-
0142259710
-
Three or more routes for leukocyte migration into the central nervous system
-
Ransohoff RM, Kivisakk P, Kidd G. 2003. Three or more routes for leukocyte migration into the central nervous system. Nat Rev Immunol 3: 569-581.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 569-581
-
-
Ransohoff, R.M.1
Kivisakk, P.2
Kidd, G.3
-
63
-
-
79952116706
-
A role for complement in glaucoma?
-
Ren L, Danias J. 2010. A role for complement in glaucoma? Adv Exp Med Biol 703: 95-104.
-
(2010)
Adv Exp Med Biol
, vol.703
, pp. 95-104
-
-
Ren, L.1
Danias, J.2
-
65
-
-
16244376480
-
Toll-like receptors, endogenous ligands, and systemic autoimmune disease
-
Rifkin IR, Leadbetter EA, Busconi L, Viglianti G, Marshak-Rothstein A. 2005. Toll-like receptors, endogenous ligands, and systemic autoimmune disease. Immunol Rev 204: 27-42.
-
(2005)
Immunol Rev
, vol.204
, pp. 27-42
-
-
Rifkin, I.R.1
Leadbetter, E.A.2
Busconi, L.3
Viglianti, G.4
Marshak-Rothstein, A.5
-
66
-
-
84863625033
-
Etanercept, a widely used inhibitor of tumor necrosis factor-a (TNF-a), prevents retinal ganglion cell loss in a rat model of glaucoma
-
Roh M, Zhang Y, Murakami Y, Thanos A, Lee SC, Vavvas DG, Benowitz LI, Miller JW. 2012. Etanercept, a widely used inhibitor of tumor necrosis factor-a (TNF-a), prevents retinal ganglion cell loss in a rat model of glaucoma. PloS ONE 7: e40065.
-
(2012)
Plos ONE
, vol.7
-
-
Roh, M.1
Zhang, Y.2
Murakami, Y.3
Thanos, A.4
Lee, S.C.5
Vavvas, D.G.6
Benowitz, L.I.7
Miller, J.W.8
-
67
-
-
79952115634
-
The role of the classical complement cascade in synapse loss during development and glaucoma
-
Rosen AM, Stevens B. 2010. The role of the classical complement cascade in synapse loss during development and glaucoma. Adv Exp Med Biol 703: 75-93.
-
(2010)
Adv Exp Med Biol
, vol.703
, pp. 75-93
-
-
Rosen, A.M.1
Stevens, B.2
-
68
-
-
57349185900
-
Astroglial metabolic networks sustain hippocampal synaptic transmission
-
Rouach N, Koulakoff A, Abudara V, Willecke K, Giaume C. 2008. Astroglial metabolic networks sustain hippocampal synaptic transmission. Science 322: 1551-1555.
-
(2008)
Science
, vol.322
, pp. 1551-1555
-
-
Rouach, N.1
Koulakoff, A.2
Abudara, V.3
Willecke, K.4
Giaume, C.5
-
69
-
-
77449132674
-
Tumor necrosis factor-a concentrations in the aqueous humor of patients with glaucoma
-
Sawada H, Fukuchi T, Tanaka T, Abe H. 2010. Tumor necrosis factor-a concentrations in the aqueous humor of patients with glaucoma. Invest Ophthalmol Vis Sci 51: 903-906.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 903-906
-
-
Sawada, H.1
Fukuchi, T.2
Tanaka, T.3
Abe, H.4
-
70
-
-
33750381831
-
Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric
-
Schlamp CL, Li Y, Dietz JA, Janssen KT, Nickells RW. 2006. Progressive ganglion cell loss and optic nerve degeneration in DBA/2J mice is variable and asymmetric. BMC Neurosci 7: 66.
-
(2006)
BMC Neurosci
, vol.7
, pp. 66
-
-
Schlamp, C.L.1
Li, Y.2
Dietz, J.A.3
Janssen, K.T.4
Nickells, R.W.5
-
71
-
-
9344248393
-
The neurobiology of glia in the context of water and ion homeostasis
-
Simard M, Nedergaard M. 2004. The neurobiology of glia in the context of water and ion homeostasis. Neuroscience 129: 877-896.
-
(2004)
Neuroscience
, vol.129
, pp. 877-896
-
-
Simard, M.1
Nedergaard, M.2
-
73
-
-
38349070853
-
Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model
-
Soto I, Oglesby E, Buckingham BP, Son JL, Roberson EDO, Steele MR, Inman DM, Vetter ML, Horner PJ, Marsh-Armstrong N. 2008. Retinal ganglion cells downregulate gene expression and lose their axons within the optic nerve head in a mouse glaucoma model. J Neurosci 28: 548-561.
-
(2008)
J Neurosci
, vol.28
, pp. 548-561
-
-
Soto, I.1
Oglesby, E.2
Buckingham, B.P.3
Son, J.L.4
Roberson, E.5
Steele, M.R.6
Inman, D.M.7
Vetter, M.L.8
Horner, P.J.9
Marsh-Armstrong, N.10
-
74
-
-
33645402376
-
Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes
-
Stasi K, Nagel D, Yang X, Wang RF, Ren L, Podos SM, Mittag T, Danias J. 2006. Complement component 1Q (C1Q) upregulation in retina of murine, primate, and human glaucomatous eyes. Invest Ophthalmol Vis Sci 47: 1024-1029.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 1024-1029
-
-
Stasi, K.1
Nagel, D.2
Yang, X.3
Wang, R.F.4
Ren, L.5
Podos, S.M.6
Mittag, T.7
Danias, J.8
-
75
-
-
33645395994
-
Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma
-
Steele MR, Inman DM, Calkins DJ, Horner PJ, Vetter ML. 2006. Microarray analysis of retinal gene expression in the DBA/2J model of glaucoma. Invest Ophthalmol Vis Sci 47: 977-985.
-
(2006)
Invest Ophthalmol Vis Sci
, vol.47
, pp. 977-985
-
-
Steele, M.R.1
Inman, D.M.2
Calkins, D.J.3
Horner, P.J.4
Vetter, M.L.5
-
76
-
-
36849076770
-
The classical complement cascade mediates CNS synapse elimination
-
Stevens B, Allen NJ, Vazquez LE, Howell GR, Christopherson KS, Nouri N, Micheva KD, Mehalow AK, Huberman AD, Stafford B, et al. 2007. The classical complement cascade mediates CNS synapse elimination. Cell 131: 1164-1178.
-
(2007)
Cell
, vol.131
, pp. 1164-1178
-
-
Stevens, B.1
Allen, N.J.2
Vazquez, L.E.3
Howell, G.R.4
Christopherson, K.S.5
Nouri, N.6
Micheva, K.D.7
Mehalow, A.K.8
Huberman, A.D.9
Stafford, B.10
-
77
-
-
84880700718
-
Reversible reactivity by optic nerve astrocytes
-
Sun D, Qu J, Jakobs TC. 2013. Reversible reactivity by optic nerve astrocytes. Glia 61: 1218-1235.
-
(2013)
Glia
, vol.61
, pp. 1218-1235
-
-
Sun, D.1
Qu, J.2
Jakobs, T.C.3
-
78
-
-
77950343791
-
Pattern recognition receptors and inflammation
-
Takeuchi O, Akira S. 2010. Pattern recognition receptors and inflammation. Cell 140: 805-820.
-
(2010)
Cell
, vol.140
, pp. 805-820
-
-
Takeuchi, O.1
Akira, S.2
-
79
-
-
84873883408
-
Astroglial integrins in the development and regulation of neurovascular units
-
Tanigami H, Okamoto T, Yasue Y, Shimaoka M. 2012. Astroglial integrins in the development and regulation of neurovascular units. Pain Res Treat 2012: 964652.
-
(2012)
Pain Res Treat
, vol.2012
, pp. 964652
-
-
Tanigami, H.1
Okamoto, T.2
Yasue, Y.3
Shimaoka, M.4
-
80
-
-
79955152463
-
Involvement of the CD200 receptor complex in microglia activation in experimental glaucoma
-
Taylor S, Calder CJ, Albon J, Erichsen JT, Boulton ME, Morgan JE. 2011. Involvement of the CD200 receptor complex in microglia activation in experimental glaucoma. Exp Eye Res 92: 338-343.
-
(2011)
Exp Eye Res
, vol.92
, pp. 338-343
-
-
Taylor, S.1
Calder, C.J.2
Albon, J.3
Erichsen, J.T.4
Boulton, M.E.5
Morgan, J.E.6
-
81
-
-
80052807932
-
The immune response in glaucoma: A perspective on the roles of oxidative stress
-
Tezel G. 2011. The immune response in glaucoma: A perspective on the roles of oxidative stress. Exp Eye Res 93: 178-186.
-
(2011)
Exp Eye Res
, vol.93
, pp. 178-186
-
-
Tezel, G.1
-
82
-
-
84871335063
-
Immune regulation toward immunomodulation for neuroprotection in glaucoma
-
Tezel G. 2013. Immune regulation toward immunomodulation for neuroprotection in glaucoma. Curr Opin Pharmacol 13: 23-31.
-
(2013)
Curr Opin Pharmacol
, vol.13
, pp. 23-31
-
-
Tezel, G.1
-
83
-
-
0034934110
-
TNF-a and TNF-a receptor-1 in the retina of normal and glaucomatous eyes
-
Tezel G, Li LY, Patil RV, Wax MB. 2001. TNF-a and TNF-a receptor-1 in the retina of normal and glaucomatous eyes. Invest Ophthalmol Vis Sci 42: 1787-1794.
-
(2001)
Invest Ophthalmol Vis Sci
, vol.42
, pp. 1787-1794
-
-
Tezel, G.1
Li, L.Y.2
Patil, R.V.3
Wax, M.B.4
-
84
-
-
1342291354
-
Heat shock proteins, immunity and glaucoma
-
Tezel G, Yang J, Wax MB. 2004. Heat shock proteins, immunity and glaucoma. Brain Res Bull 62: 473-480.
-
(2004)
Brain Res Bull
, vol.62
, pp. 473-480
-
-
Tezel, G.1
Yang, J.2
Wax, M.B.3
-
85
-
-
77958118316
-
Oxidative stress and the regulation of complement activation in human glaucoma
-
Tezel G, Yang X, Luo C, Kain AD, Powell DW, Kuehn MH, Kaplan HJ. 2010. Oxidative stress and the regulation of complement activation in human glaucoma. Invest Ophthalmol Vis Sci 51: 5071-5082.
-
(2010)
Invest Ophthalmol Vis Sci
, vol.51
, pp. 5071-5082
-
-
Tezel, G.1
Yang, X.2
Luo, C.3
Kain, A.D.4
Powell, D.W.5
Kuehn, M.H.6
Kaplan, H.J.7
-
86
-
-
84866296520
-
An astrocyte-specific proteomic approach to inflammatory responses in experimental rat glaucoma
-
Tezel G, Yang X, Luo C, Cai J, Powell DW. 2012. An astrocyte-specific proteomic approach to inflammatory responses in experimental rat glaucoma. Invest Ophthalmol Vis Sci 53: 4220-4233.
-
(2012)
Invest Ophthalmol Vis Sci
, vol.53
, pp. 4220-4233
-
-
Tezel, G.1
Yang, X.2
Luo, C.3
Cai, J.4
Powell, D.W.5
-
88
-
-
0036202327
-
Immunohistologic evidence for retinal glial cell changes in human glaucoma
-
Wang L, Cioffi GA, Cull G, Dong J, Fortune B. 2002. Immunohistologic evidence for retinal glial cell changes in human glaucoma. Invest Ophthalmol Vis Sci 43: 1088-1094.
-
(2002)
Invest Ophthalmol Vis Sci
, vol.43
, pp. 1088-1094
-
-
Wang, L.1
Cioffi, G.A.2
Cull, G.3
Dong, J.4
Fortune, B.5
-
89
-
-
0034128172
-
Matrix metal-loproteinases and tumor necrosis factor a in glaucomatous optic nerve head
-
Yan X, Tezel G, Wax MB, Edward DP. 2000. Matrix metal-loproteinases and tumor necrosis factor a in glaucomatous optic nerve head. Arch Ophthalmol 118: 666-673.
-
(2000)
Arch Ophthalmol
, vol.118
, pp. 666-673
-
-
Yan, X.1
Tezel, G.2
Wax, M.B.3
Edward, D.P.4
-
90
-
-
38549145937
-
Changes in gene expression in experimental glaucoma and optic nerve transection: The equilibrium between protective and detrimental mechanisms
-
Yang Z, Quigley HA, Pease ME, Yang Y, Qian J, Valenta D, Zack DJ. 2007. Changes in gene expression in experimental glaucoma and optic nerve transection: The equilibrium between protective and detrimental mechanisms. Invest Ophthalmol Vis Sci 48: 5539-5548.
-
(2007)
Invest Ophthalmol Vis Sci
, vol.48
, pp. 5539-5548
-
-
Yang, Z.1
Quigley, H.A.2
Pease, M.E.3
Yang, Y.4
Qian, J.5
Valenta, D.6
Zack, D.J.7
-
91
-
-
84863846975
-
Neurodegenerative and inflammatory pathway components linked to TNF-a/TNFR1 signaling in the glaucomatous human retina
-
Yang X, Luo C, Cai J, Powell DW, Yu D, Kuehn MH, Tezel G. 2011. Neurodegenerative and inflammatory pathway components linked to TNF-a/TNFR1 signaling in the glaucomatous human retina. Invest Ophthalmol Vis Sci 52: 8442-8454.
-
(2011)
Invest Ophthalmol Vis Sci
, vol.52
, pp. 8442-8454
-
-
Yang, X.1
Luo, C.2
Cai, J.3
Powell, D.W.4
Yu, D.5
Kuehn, M.H.6
Tezel, G.7
-
92
-
-
0033781980
-
Tumor necrosis factor-a: A potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head
-
Yuan L, Neufeld AH. 2000. Tumor necrosis factor-a: A potentially neurodestructive cytokine produced by glia in the human glaucomatous optic nerve head. Glia 32: 42-50.
-
(2000)
Glia
, vol.32
, pp. 42-50
-
-
Yuan, L.1
Neufeld, A.H.2
-
93
-
-
0035370336
-
Activated microglia in the human glaucomatous optic nerve head
-
Yuan L, Neufeld AH. 2001. Activated microglia in the human glaucomatous optic nerve head. J Neurosci Res 64: 523-532.
-
(2001)
J Neurosci Res
, vol.64
, pp. 523-532
-
-
Yuan, L.1
Neufeld, A.H.2
-
94
-
-
78649696296
-
Endogenous toll-like receptor ligands and their biological significance
-
Yu L, Wang L, Chen S. 2010. Endogenous toll-like receptor ligands and their biological significance. J Cell Mol Med 14: 2592-2603.
-
(2010)
J Cell Mol Med
, vol.14
, pp. 2592-2603
-
-
Yu, L.1
Wang, L.2
Chen, S.3
-
95
-
-
77950275298
-
Circulating mitochondrial DAMPs cause inflammatory responses to injury
-
Zhang Q, Raoof M, Chen Y, Sumi Y, Sursal T, Junger W, Brohi K, Itagaki K, Hauser CJ. 2010. Circulating mitochondrial DAMPs cause inflammatory responses to injury. Nature 464: 104-107.
-
(2010)
Nature
, vol.464
, pp. 104-107
-
-
Zhang, Q.1
Raoof, M.2
Chen, Y.3
Sumi, Y.4
Sursal, T.5
Junger, W.6
Brohi, K.7
Itagaki, K.8
Hauser, C.J.9
-
96
-
-
78751630027
-
An efficient delivery of DAMPs on the cell surface by the unconventional secretion pathway
-
Zhu H, Wang L, Ruan Y, Zhou L, Zhang D, Min Z, Xie J, Yu M, Gu J. 2011. An efficient delivery of DAMPs on the cell surface by the unconventional secretion pathway. Biochem Biophys Res Commun 404: 790-795.
-
(2011)
Biochem Biophys Res Commun
, vol.404
, pp. 790-795
-
-
Zhu, H.1
Wang, L.2
Ruan, Y.3
Zhou, L.4
Zhang, D.5
Min, Z.6
Xie, J.7
Yu, M.8
Gu, J.9
|