Identification of amino acid residues essential for heparin binding by the A1 domain of human von Willebrand factor

Biochemical and Biophysical Research Communications

Volumn 339, Issue 4, 2006, Pages 1178-1183

  Adachi, Tatsuya ^a   Matsushita, Tadashi ^a   Dong, Zhengyu ^b   Katsumi, Akira ^a   Nakayama, Takayuki ^a   Kojima, Tetsuhito ^c   Saito, Hidehiko ^d   Sadler, J Evan ^b   Naoe, Tomoki ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NAGOYA UNIVERSITY   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION NAGOYA MEDICAL CENTER   (Japan)

Author keywords

ADAMTS13; Alanine scanning mutagenesis; Blood coagulation; Glycoprotein Ib; Heparin; Platelet; Thrombosis; Von Willebrand factor

Indexed keywords

ALANINE; AMINO ACID; ARGININE; HEPARIN; LYSINE; SEPHAROSE; VON WILLEBRAND FACTOR;

AMINO ACID ANALYSIS; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CONCENTRATION RESPONSE; HUMAN; HUMAN CELL; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN;

AMINO ACID SUBSTITUTION; AMINO ACIDS; BINDING SITES; COMPUTER SIMULATION; EXTRACELLULAR MATRIX PROTEINS; HEPARIN; HUMANS; MODELS, CHEMICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; VON WILLEBRAND FACTOR;

ANIMALIA;

EID: 29144487085     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2005.11.126     Document Type: Article

References (36)

1. T.B. Tschopp, H.J. Weiss, and H.R. Baumgartner Decreased adhesion of platelets to subendothelium in von Willebrand's disease J. Lab. Clin. Med. 83 1974 296 300
2. K.S. Sakariassen, P.A. Bolhuis, and J.J. Sixma Human blood platelet adhesion to artery subendothelium is mediated by factor VIII-von Willebrand factor bound to the subendothelium Nature 279 1979 636 638
3. J.E. Sadler von Willebrand disease C.R. Scriver A.L. Beaudet W.S. Sly D. Valle The Metabolic and Molecular Basis of Inherited Disease 1995 McGraw-Hill New York 3269 3287
4. H.J. Weiss von Willebrand factor and platelet function Ann. N.Y. Acad. Sci. 614 1991 125 137
5. C.A. Siedlecki, B.J. Lestini, K. Kottkemarchant, S.J. Eppell, D.L. Wilson, and R.E. Marchant Shear-dependent changes in the three-dimensional structure of human von Willebrand factor Blood 88 1996 2939 2950
6. H.V. Stel, K.S. Sakariassen, P.G. de Groot, J.A. van Mourik, and J.J. Sixma von Willebrand factor in the vessel wall mediates platelet adherence Blood 65 1985 85 90
7. V.T. Turitto, H.J. Weiss, T.S. Zimmerman, and I.I. Sussman Factor VIII/von Willebrand factor in subendothelium mediates platelet adhesion Blood 65 1985 823 831
8. M.S. Read, S.V. Smith, M.A. Lamb, and K.M. Brinkhous Role of botrocetin in platelet agglutination: formation of an activated complex of botrocetin and von Willebrand factor Blood 74 1989 1031 1035
9. T. Matsushita, D. Meyer, and J.E. Sadler Localization of von Willebrand factor-binding sites for platelet glycoprotein Ib and botrocetin by charged-to-alanine scanning mutagenesis J. Biol. Chem. 275 2000 11044 11049
10. J.P. Scott, R.R. Montgomery, and G.S. Retzinger Dimeric ristocetin flocculates proteins, binds to platelets, and mediates von Willebrand factor-dependent agglutination of platelets J. Biol. Chem. 266 1991 8149 8155
11. M. Sobel, P.M. McNeill, P.L. Carlson, J.C. Kermode, B. Adelman, R. Conroy, and D. Marques Heparin inhibition of von Willebrand factor-dependent platelet function in vitro and in vivo J. Clin. Invest. 87 1991 1787 1793
12. M. Sobel, K.E. Bird, R. Tyler-Cross, D. Marques, N. Toma, H.E. Conrad, and R.B. Harris Heparins designed to specifically inhibit platelet interactions with von Willebrand factor Circulation 93 1996 992 999
13. L.F. Poletti, K.E. Bird, D. Marques, R.B. Harris, Y. Suda, and M. Sobel Structural aspects of heparin responsible for interactions with von Willebrand factor Arterioscler. Thromb. Vasc. Biol. 17 1997 925 931
14. J.L. Moake, C.K. Rudy, J.H. Troll, M.J. Weinstein, N.M. Colannino, J. Azocar, R.H. Seder, S.L. Hong, and D. Deykin Unusually large plasma factor VIII:von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura N. Engl. J. Med. 307 1982 1432 1435
15. H.M. Tsai, R.L. Nagel, V.B. Hatcher, and I.I. Sussman Multimeric composition of endothelial cell-derived von Willebrand factor Blood 73 1989 2074 2076
16. M. Arya, B. Anvari, G.M. Romo, M.A. Cruz, J.-F. Dong, L.V. McIntire, J.L. Moake, and J.A. Lopez Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers Blood 99 2002 3971 3977
17. J.-f. Dong, J.L. Moake, A. Bernardo, K. Fujikawa, C. Ball, L. Nolasco, J.A. Lopez, and M.A. Cruz ADAMTS-13 metalloprotease interacts with the endothelial cell-derived ultra-large von Willebrand factor J. Biol. Chem. 278 2003 29633 29639
18. H.M. Tsai Physiologic cleavage of von Willebrand factor by a plasma protease is dependent on its conformation and requires calcium ion Blood 87 1996 4235 4244
19. M. Furlan, R. Robles, and B. Lamie Partial purification and characterization of a protease from human plasma cleaving von Willebrand factor to fragments produced by in vivo proteolysis Blood 87 1996 4223 4234
20. K. Nishio, P.J. Anderson, X.L. Zheng, and J.E. Sadler Binding of platelet glycoprotein Ibalpha to von Willebrand factor domain A1 stimulates the cleavage of the adjacent domain A2 by ADAMTS13 Proc. Natl. Acad. Sci. USA 101 2004 10578 10583
21. S.A. Santoro Adsorption of von Willebrand factor/factor VIII by the genetically distinct interstitial collagens Thromb. Res. 21 1981 689 691
22. Y. Fujimura, K. Titani, L.Z. Holland, J.R. Roberts, P. Kostel, Z.M. Ruggeri, and T.S. Zimmerman A heparin-binding domain of human von Willebrand factor. Characterization and localization to a tryptic fragment extending from amino acid residue Val-449 to Lys-728 J. Biol. Chem. 262 1987 1734 1739
23. H. Mohri, A. Yoshioki, T.S. Zimmerman, and Z.M. Ruggeri Isolation of the von Willebrand factor domain interacting with platelet glycoprotein Ib, heparin, and collagen and characterization of its three distinct functional sites J. Biol. Chem. 264 1989 17361 17367
24. Y. Fujimura, L.Z. Holland, Z.M. Ruggeri, and T.S. Zimmerman The von willebrand factor domain-mediating botrocetin-induced binding to glycoprotein IB lies between Val449 and Lys728 Blood 70 1987 985 988
25. M. Sobel, D.F. Soler, J.C. Kermode, and R.B. Harris Localization and characterization of a heparin binding domain peptide of human von Willebrand factor J. Biol. Chem. 267 1992 8857 8862
26. L.J. Fretto, W.E. Fowler, D.R. McCaslin, H.P. Erickson, and P.A. McKee Substructure of human von Willebrand factor. Proteolysis by V8 and characterization of two functional domains J. Biol. Chem. 261 1986 15679 15689
27. I. Bodo, A. Katsumi, E.A. Tuley, J.C. Eikenboom, Z. Dong, and J.E. Sadler Type 1 von Willebrand disease mutation Cys1149Arg causes intracellular retention and degradation of heterodimers: a possible general mechanism for dominant mutations of oligomeric proteins Blood 98 2001 2973 2979
28. T. Matsushita, and J.E. Sadler Identification of amino acid residues essential for von Willebrand factor binding to platelet glycoprotein Ib. Charged-to-alanine scanning mutagenesis of the A1 domain of human von Willebrand factor J. Biol. Chem. 270 1995 13406 13414
29. C. Chen, and H. Okayama High-efficiency transformation of mammalian cells by plasmid DNA Mol. Cell. Biol. 7 1987 2745 2752
30. E.A. Tuley, C. Gaucher, S. Jorieux, N.K. Worrall, J.E. Sadler, and C. Mazurier Expression of von Willebrand factor "Normandy: an autosomal mutation that mimics hemophilia A Proc. Natl. Acad. Sci. USA 88 1991 6377 6381
31. C. de Romeuf, and C. Mazurier Heparin binding assay of von Willebrand factor (vWF) in plasma milieu-evidence of the importance of the multimerization degree of vWF Thromb. Haemost. 69 1993 436 440
32. A.M. Randi, S. Jorieux, E.A. Tuley, C. Mazurier, and J.E. Sadler Recombinant von Willebrand factor Arg578→Gln. A type IIB von Willebrand disease mutation affects binding to glycoprotein Ib but not to collagen or heparin J. Biol. Chem. 267 1992 21187 21192
33. E.G. Huizinga, S. Tsuji, R.A. Romijn, M.E. Schiphorst, P.G. de Groot, J.J. Sixma, and P. Gros Structures of glycoprotein Ibalpha and its complex with von Willebrand factor A1 domain Science 297 2002 1176 1179
34. J.J. Sixma, M.E. Schiphorst, C.L. Verweij, and H. Pannekoek Effect of deletion of the A1 domain of von Willebrand factor on its binding to heparin, collagen and platelets in the presence of ristocetin Eur. J. Biochem. 96 1991 369 375
35. G. Rastegar-Lari, B.O. Villoutreix, A.S. Ribba, P. Legendre, D. Meyer, and D. Baruch Two clusters of charged residues located in the electropositive face of the von Willebrand factor A1 domain are essential for heparin binding Biochemistry 41 2002 6668 6678
36. P.A. Kroner, and A.B. Frey Analysis of the structure and function of the von Willebrand factor A1 domain using targeted deletions and alanine-scanning mutagenesis Biochemistry 35 1996 13460 13468