Synthetic signal sequences that enable efficient secretory protein production in the yeast Kluyveromyces marxianus

Microbial Cell Factories

Volumn 14, Issue 1, 2015, Pages

  Yarimizu, Tohru ^a,c   Nakamura, Mikiko ^b   Hoshida, Hisashi ^a   Akada, Rinji ^a  

^a YAMAGUCHI UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b YAMAGUCHI UNIVERSITY   (Japan)

^c NATIONAL INSTITUTE FOR AGRO ENVIRONMENTAL SCIENCES   (Japan)

Author keywords

Heterologous protein production; Hydrophobic core; Secretion; Synthetic signal sequence; Thermotolerant yeast

Indexed keywords

FUNGAL PROTEIN; GLUTAMIC ACID; ISOLEUCINE; LEUCINE; LEUKEMIA INHIBITORY FACTOR; LUCIFERASE; LYSINE; METHIONINE; PHENYLALANINE; SECRETORY LUCIFERASE; SECRETORY PROTEIN; SIGNAL PEPTIDE; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; AMINO ACID; ARTHROPOD PROTEIN; LIF PROTEIN, HUMAN; PEPTIDE; RECOMBINANT PROTEIN;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CLONING; CONTROLLED STUDY; COPEPOD; ENZYME ACTIVITY; GAUSSIA PRINCEPS; GENE DELETION; HETEROLOGOUS EXPRESSION; HYDROPHILICITY; HYDROPHOBICITY; KLUYVEROMYCES MARXIANUS; MUTATIONAL ANALYSIS; NONHUMAN; PROTEIN DOMAIN; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL; CHEMICAL PHENOMENA; CHEMISTRY; ENZYMOLOGY; GENE EXPRESSION; GENETICS; HUMAN; KLUYVEROMYCES; METABOLISM; MOLECULAR GENETICS; MUTATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; WESTERN BLOTTING;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; AMINO ACIDS; ANIMALS; ARTHROPOD PROTEINS; BLOTTING, WESTERN; COPEPODA; GENE EXPRESSION; HUMANS; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; KLUYVEROMYCES; LEUKEMIA INHIBITORY FACTOR; LUCIFERASES; MOLECULAR SEQUENCE DATA; MUTATION; PEPTIDES; PROTEIN SORTING SIGNALS; RECOMBINANT PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 84928711716     PISSN: None     EISSN: 14752859     Source Type: Journal    
DOI: 10.1186/s12934-015-0203-y     Document Type: Article

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