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Volumn 59, Issue 3, 2012, Pages 607-613

Neovascularization is attenuated with aldosterone synthase inhibition in rats with retinopathy

Author keywords

aldosterone; microglia; neovascularization; oxygen induced retinopathy; retina

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE 2; ALDOSTERONE; ALDOSTERONE ANTAGONIST; ALDOSTERONE SYNTHASE; FAD 286; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; MINERALOCORTICOID RECEPTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VALSARTAN; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN;

EID: 84857567891     PISSN: 0194911X     EISSN: 15244563     Source Type: Journal    
DOI: 10.1161/HYPERTENSIONAHA.111.188136     Document Type: Article
Times cited : (64)

References (41)
  • 3
    • 0030040965 scopus 로고    scopus 로고
    • Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: Evidence for an intraocular renin-angiotensin system
    • Wagner J, Jan Danser AH, Derkx FH, de Jong TV, Paul M, Mullins JJ, Schalekamp MA, Ganten D. Demonstration of renin mRNA, angiotensinogen mRNA, and angiotensin converting enzyme mRNA expression in the human eye: evidence for an intraocular renin-angiotensin system. Br J Ophthalmol. 1996;80:159-163. (Pubitemid 26058551)
    • (1996) British Journal of Ophthalmology , vol.80 , Issue.2 , pp. 159-163
    • Wagner, J.1    Danser, A.H.J.2    Derkx, F.H.M.3    De Jong, P.T.V.M.4    Paul, M.5    Mullins, J.J.6    Schalekamp, M.A.D.H.7    Ganten, D.8
  • 5
    • 59649118170 scopus 로고    scopus 로고
    • Identification of a retinal aldosterone system and the protective effects of mineralocorticoid receptor antagonism on retinal vascular pathology
    • Wilkinson-Berka JL, Tan G, Jaworski K, Miller AG. Identification of a retinal aldosterone system and the protective effects of mineralocorticoid receptor antagonism on retinal vascular pathology. Circ Res. 2009;104: 124-133.
    • (2009) Circ Res. , vol.104 , pp. 124-133
    • Wilkinson-Berka, J.L.1    Tan, G.2    Jaworski, K.3    Miller, A.G.4
  • 12
    • 33947326902 scopus 로고    scopus 로고
    • Valsartan but not Atenolol Improves Vascular Pathology in Diabetic Ren-2 Rat Retina
    • DOI 10.1016/j.amjhyper.2006.09.018, PII S0895706106006303
    • Wilkinson-Berka JL, Tan G, Jaworski K, Ninkovic S. Valsartan but not atenolol improves vascular pathology in diabetic Ren-2 rat retina. Am J Hypertens. 2007;20:423-430. (Pubitemid 46441750)
    • (2007) American Journal of Hypertension , vol.20 , Issue.4 , pp. 423-430
    • Wilkinson-Berka, J.L.1    Tan, G.2    Jaworski, K.3    Ninkovic, S.4
  • 14
    • 53749100124 scopus 로고    scopus 로고
    • Effect of candesartan on prevention (DIRECT-prevent 1) and progression (DIRECT-protect 1) of retinopathy in type 1 diabetes: Randomised, placebo-controlled trials
    • Chaturvedi N, Porta M, Klein R, Orchard T, Fuller J, Parving HH, Bilous R, Sjolie AK. Effect of candesartan on prevention (DIRECT-prevent 1) and progression (DIRECT-protect 1) of retinopathy in type 1 diabetes: randomised, placebo-controlled trials. Lancet. 2008;372:1394-1402.
    • (2008) Lancet. , vol.372 , pp. 1394-1402
    • Chaturvedi, N.1    Porta, M.2    Klein, R.3    Orchard, T.4    Fuller, J.5    Parving, H.H.6    Bilous, R.7    Sjolie, A.K.8
  • 15
    • 53749108177 scopus 로고    scopus 로고
    • Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-protect 2): A randomised placebo-controlled trial
    • Sjolie AK, Klein R, Porta M, Orchard T, Fuller J, Parving HH, Bilous R, Chaturvedi N. Effect of candesartan on progression and regression of retinopathy in type 2 diabetes (DIRECT-protect 2): a randomised placebo-controlled trial. Lancet. 2008;372:1385-1393.
    • (2008) Lancet. , vol.372 , pp. 1385-1393
    • Sjolie, A.K.1    Klein, R.2    Porta, M.3    Orchard, T.4    Fuller, J.5    Parving, H.H.6    Bilous, R.7    Chaturvedi, N.8
  • 17
    • 34548420712 scopus 로고    scopus 로고
    • Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the ADVANCE trial): A randomised controlled trial
    • DOI 10.1016/S0140-6736(07)61303-8, PII S0140673607613038
    • Patel A, MacMahon S, Chalmers J, Neal B, Woodward M, Billot L, Harrap S, Poulter N, Marre M, Cooper M, Glasziou P, Grobbee DE, Hamet P, Heller S, Liu LS, Mancia G, Mogensen CE, Pan CY, Rodgers A, Williams B. Effects of a fixed combination of perindopril and indapamide on macrovascular and microvascular outcomes in patients with type 2 diabetes mellitus (the Advance trial): a randomised controlled trial. Lancet. 2007;370:829-840. (Pubitemid 47362321)
    • (2007) Lancet , vol.370 , Issue.9590 , pp. 829-840
    • Patel, A.1
  • 18
    • 0032511601 scopus 로고    scopus 로고
    • Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes
    • UK Prospective Diabetes Study Group
    • UK Prospective Diabetes Study Group. Efficacy of atenolol and captopril in reducing risk of macrovascular and microvascular complications in type 2 diabetes. BMJ. 1998;317:713-720.
    • (1998) BMJ. , vol.317 , pp. 713-720
  • 19
    • 64949189157 scopus 로고    scopus 로고
    • Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt
    • Lea WB, Kwak ES, Luther JM, Fowler SM, Wang Z, Ma J, Fogo AB, Brown NJ. Aldosterone antagonism or synthase inhibition reduces end-organ damage induced by treatment with angiotensin and high salt. Kidney Int. 2009;75:936-944.
    • (2009) Kidney Int. , vol.75 , pp. 936-944
    • Lea, W.B.1    Kwak, E.S.2    Luther, J.M.3    Fowler, S.M.4    Wang, Z.5    Ma, J.6    Fogo, A.B.7    Brown, N.J.8
  • 20
    • 46149104414 scopus 로고    scopus 로고
    • Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats
    • DOI 10.1113/expphysiol.2008.042085
    • Siragy HM, Xue C. Local renal aldosterone production induces inflammation and matrix formation in kidneys of diabetic rats. Exp Physiol. 2008;93:817-824. (Pubitemid 351904248)
    • (2008) Experimental Physiology , vol.93 , Issue.7 , pp. 817-824
    • Siragy, H.M.1    Xue, C.2
  • 22
    • 34548163060 scopus 로고    scopus 로고
    • The incidence and implications of aldosterone breakthrough
    • DOI 10.1038/ncpneph0575, PII NCPNEPH0575
    • Bomback AS, Klemmer PJ. The incidence and implications of aldosterone breakthrough. Nat Clin Pract Nephrol. 2007;3:486-492. (Pubitemid 47313030)
    • (2007) Nature Clinical Practice Nephrology , vol.3 , Issue.9 , pp. 486-492
    • Bomback, A.S.1    Klemmer, P.J.2
  • 24
    • 33646828753 scopus 로고    scopus 로고
    • Investigation of aldosterone-synthase inhibition in rats
    • DOI 10.1097/01.hjh.0000226205.65442.f2, PII 0000487220060600000024
    • Menard J, Gonzalez MF, Guyene TT, Bissery A. Investigation of aldosterone- synthase inhibition in rats. J Hypertens. 2006;24:1147-1155. (Pubitemid 43772323)
    • (2006) Journal of Hypertension , vol.24 , Issue.6 , pp. 1147-1155
    • Menard, J.1    Gonzalez, M.-F.2    Guyene, T.-T.3    Bissery, A.4
  • 26
    • 2142694344 scopus 로고    scopus 로고
    • Aldosterone enhances ischemia-induced neovascularization through angiotensin ii-dependent pathway
    • DOI 10.1161/01.CIR.0000127112.36796.9B
    • Michel F, Ambroisine ML, Duriez M, Delcayre C, Levy BI, Silvestre JS. Aldosterone enhances ischemia-induced neovascularization through angiotensin II-dependent pathway. Circulation. 2004;109:1933-1937. (Pubitemid 38544481)
    • (2004) Circulation , vol.109 , Issue.16 , pp. 1933-1937
    • Michel, F.1    Ambroisine, M.-L.2    Duriez, M.3    Delcayre, C.4    Levy, B.I.5    Silvestre, J.-S.6
  • 27
    • 65649120479 scopus 로고    scopus 로고
    • Role of angiotensin II type 1 receptor on retinal vascular leakage in a rat oxygen-induced retinopathy model
    • Nakamura H, Yamazaki M, Ohyama T, Inoue T, Arakawa N, Domon Y, Yokoyama T. Role of angiotensin II type 1 receptor on retinal vascular leakage in a rat oxygen-induced retinopathy model. Ophthalmic Res. 2009;41:210-215.
    • (2009) Ophthalmic Res. , vol.41 , pp. 210-215
    • Nakamura, H.1    Yamazaki, M.2    Ohyama, T.3    Inoue, T.4    Arakawa, N.5    Domon, Y.6    Yokoyama, T.7
  • 29
    • 85027923977 scopus 로고    scopus 로고
    • FAD286, an aldosterone synthase inhibitor, reduced atherosclerosis and inflammation in apolipoprotein e-deficient mice
    • Gamliel-Lazarovich A, Gantman A, Coleman R, Jeng AY, Kaplan M, Keidar S. FAD286, an aldosterone synthase inhibitor, reduced atherosclerosis and inflammation in apolipoprotein e-deficient mice. J Hypertens. 2010;28:1900-1907.
    • (2010) J Hypertens. , vol.28 , pp. 1900-1907
    • Gamliel-Lazarovich, A.1    Gantman, A.2    Coleman, R.3    Jeng, A.Y.4    Kaplan, M.5    Keidar, S.6
  • 31
    • 77953749176 scopus 로고    scopus 로고
    • Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: Comparison with the 11-hydroxylase inhibitor metyrapone
    • Rigel DF, Fu F, Beil M, Hu CW, Liang G, Jeng AY. Pharmacodynamic and pharmacokinetic characterization of the aldosterone synthase inhibitor FAD286 in two rodent models of hyperaldosteronism: comparison with the 11-hydroxylase inhibitor metyrapone. J Pharmacol Exp Ther. 2010;334:232-243.
    • (2010) J Pharmacol Exp Ther. , vol.334 , pp. 232-243
    • Rigel, D.F.1    Fu, F.2    Beil, M.3    Hu, C.W.4    Liang, G.5    Jeng, A.Y.6
  • 32
    • 0036125995 scopus 로고    scopus 로고
    • Oxygen-dependence of ACTH-stimulated aldosterone and corticosterone synthesis in the rat adrenal cortex: Developmental aspects
    • DOI 10.1677/joe.0.1720595
    • Bruder ED, Nagler AK, Raff H. Oxygen-dependence of ACTHstimulated aldosterone and corticosterone synthesis in the rat adrenal cortex: developmental aspects. J Endocrinol. 2002;172:595-604. (Pubitemid 34232701)
    • (2002) Journal of Endocrinology , vol.172 , Issue.3 , pp. 595-604
    • Bruder, E.D.1    Nagler, A.K.2    Raff, H.3
  • 33
    • 0028211791 scopus 로고
    • Inhibition of aldosterone release by hypoxia in vitro: Interaction with carbon monoxide
    • Raff H, Jankowski B. Inhibition of aldosterone release by hypoxia in vitro: Interaction with carbon monoxide. J Appl Physiol. 1994;76: 689-693. (Pubitemid 24075614)
    • (1994) Journal of Applied Physiology , vol.76 , Issue.2 , pp. 689-693
    • Raff, H.1    Jankowski, B.2
  • 35
    • 70549094339 scopus 로고    scopus 로고
    • Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy
    • Dorrell MI, Aguilar E, Jacobson R, Trauger SA, Friedlander J, Siuzdak G, Friedlander M. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy. Glia. 2010;58:43-54.
    • (2010) Glia. , vol.58 , pp. 43-54
    • Dorrell, M.I.1    Aguilar, E.2    Jacobson, R.3    Trauger, S.A.4    Friedlander, J.5    Siuzdak, G.6    Friedlander, M.7
  • 36
    • 3042538729 scopus 로고    scopus 로고
    • Induction of IL-8, MPC-1, and bFGF by TNF- in retinal glial cells: Implications for retinal neovascularization during post-ischemic inflammation
    • DOI 10.1007/s00417-004-0874-2
    • Yoshida S, Yoshida A, Ishibashi T. Induction of IL-8, MCP-1, and bFGF by TNF- in retinal glial cells: implications for retinal neovascularization during post-ischemic inflammation. Graefes Arch Clin Exp Ophthalmol. 2004;242:409-413. (Pubitemid 38801529)
    • (2004) Graefe's Archive for Clinical and Experimental Ophthalmology , vol.242 , Issue.5 , pp. 409-413
    • Yoshida, S.1    Yoshida, A.2    Ishibashi, T.3
  • 37
    • 3843102579 scopus 로고    scopus 로고
    • Do human vascular endothelial cells produce aldosterone?
    • DOI 10.1210/en.2004-0081
    • Ahmad N, Romero DG, Gomez-Sanchez EP, Gomez-Sanchez CE. Do human vascular endothelial cells produce aldosterone? Endocrinology. 2004;145:3626-3629. (Pubitemid 39037546)
    • (2004) Endocrinology , vol.145 , Issue.8 , pp. 3626-3629
    • Ahmad, N.1    Romero, D.G.2    Gomez-Sanchez, E.P.3    Gomez-Sanchez, C.E.4
  • 38
    • 51349130208 scopus 로고    scopus 로고
    • AT1 receptor inhibition prevents astrocyte degeneration and restores vascular growth in oxygen-induced retinopathy
    • Downie LE, Pianta MJ, Vingrys AJ, Wilkinson-Berka JL, Fletcher EL. AT1 receptor inhibition prevents astrocyte degeneration and restores vascular growth in oxygen-induced retinopathy. Glia. 2008;56: 1076-1090.
    • (2008) Glia. , vol.56 , pp. 1076-1090
    • Downie, L.E.1    Pianta, M.J.2    Vingrys, A.J.3    Wilkinson-Berka, J.L.4    Fletcher, E.L.5
  • 40
    • 41949129627 scopus 로고    scopus 로고
    • Is there a relationship between blood pressure and intraocular pressure? An experimental study in hypertensive rats
    • DOI 10.1080/02713680802011679, PII 792016451
    • Vaajanen A, Mervaala E, Oksala O, Vapaatalo H. Is there a relationship between blood pressure and intraocular pressure? An experimental study in hypertensive rats. Curr Eye Res. 2008;33:325-332. (Pubitemid 351507758)
    • (2008) Current Eye Research , vol.33 , Issue.4 , pp. 325-332
    • Vaajanen, A.1    Mervaala, E.2    Oksala, O.3    Vapaatalo, H.4
  • 41
    • 73349132037 scopus 로고    scopus 로고
    • Neuroprotective effects of angiotensin II type 1 receptor blocker in a rat model of chronic glaucoma
    • Yang H, Hirooka K, Fukuda K, Shiraga F. Neuroprotective effects of angiotensin II type 1 receptor blocker in a rat model of chronic glaucoma. Invest Ophthalmol Vis Sci. 2009;50:5800-5804.
    • (2009) Invest Ophthalmol Vis Sci. , vol.50 , pp. 5800-5804
    • Yang, H.1    Hirooka, K.2    Fukuda, K.3    Shiraga, F.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.