Beneficial effect of cyclosporine A on traumatic hemorrhagic shock

Journal of Surgical Research

Volumn 195, Issue 2, 2015, Pages 529-540

  Lei, Yan ^a,b   Peng, Xiaoyong ^b   Liu, Liangming ^b   Dong, Zhaojun ^a   Li, Tao ^b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cyclosporine A; Mitochondrial permeability transition pore; Rho associated; serine threonine kinase; Traumatic hemorrhagic shock; Vascular hyporeactivity

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; ACETYLCHOLINE; CYCLOSPORIN A; INTERLEUKIN 1BETA; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; NORADRENALIN; PROTEIN KINASE C; PROTEIN SERINE THREONINE KINASE; RHO ASSOCIATED SERINE THREONINE KINASE; RINGER LACTATE SOLUTION; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; CYCLOSPORIN; CYTOKINE; LACTIC ACID; RHO KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD FLOW; BLOOD PH; BLOOD VESSEL REACTIVITY; CONTROLLED STUDY; ENZYME ACTIVITY; FEMALE; FEMUR FRACTURE; HEART LEFT VENTRICLE PRESSURE; HEART OUTPUT; HEART RATE; HEMODYNAMICS; HEMORRHAGIC SHOCK; KIDNEY FUNCTION; LIVER FUNCTION; MALE; MEAN ARTERIAL PRESSURE; MITOCHONDRION; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RAT; RESPIRATION CONTROL; SUPERIOR MESENTERIC ARTERY; SYSTOLIC BLOOD PRESSURE; TISSUE BLOOD FLOW; TISSUE PERFUSION; TRAUMATIC HEMORRHAGIC SHOCK; VASCULAR SMOOTH MUSCLE CELL; ANIMAL; BLOOD; KIDNEY; LIVER; PATHOPHYSIOLOGY; PH; PHYSIOLOGY; SHOCK, HEMORRHAGIC; SHOCK, TRAUMATIC; SPRAGUE DAWLEY RAT;

ANIMALS; CYCLOSPORINE; CYTOKINES; FEMALE; HEMODYNAMICS; HYDROGEN-ION CONCENTRATION; KIDNEY; LACTIC ACID; LIVER; MALE; MITOCHONDRIA; PROTEIN KINASE C; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; SHOCK, HEMORRHAGIC; SHOCK, TRAUMATIC;

EID: 84928648602     PISSN: 00224804     EISSN: 10958673     Source Type: Journal    
DOI: 10.1016/j.jss.2015.02.005     Document Type: Article

References (35)

1. World Health Organisation: Global forum on trauma care. Available at: http://www.who.int/violence-injury-prevention/media/events/gftc/en/. Accessed October 20, 2014.
2. R.F. Bellamy The cause of death in conventional land warfare: implication for combat casualty care research Mil Med 149 1984 55
3. L.M. Liu, K.L. Tian, and M.Y. Xue Small doses of arginine vasopressin in combination with norepinephrine "buy" time for definitive treatment for uncontrolled hemorrhagic shock in rats Shock 40 2013 398
4. T. Li, L.M. Liu, and J.C. Liu Mechanisms of Rho kinase regulation of vascular reactivity following hemorrhagic shock in rats Shock 29 2008 65
5. J. Xu, D. Lan, T. Li, G.M. Yang, and L. Liu Angiopoietins regulate vascular reactivity after hemorrhagic shock in rats through the Tie2-nitric oxide pathway Cardiovasc Res 96 2012 308
6. A. Hasan, and K.H. McDonough The effects of Escherichia coli sepsis and short-term ischemia on coronary vascular reactivity and myocardial function Shock 8 1997 305
7. T. Shahzad, S.A. Kasseckert, and W. Iraqi Mechanisms involved in post-conditioning protection of cardiomyocytes against acute reperfusion injury J Mol Cell Cardiol 58 2013 209
8. K.A. Webster Mitochondrial membrane permeabilization and cell death during myocardial infarction: roles of calcium and reactive oxygen species Future Cardiol 8 2012 863
9. A.V. Vaseva, N.D. Marchenko, K. Ji, S.E. Tsirka, S. Holzmann, and U.M. Moll p53 opens the mitochondrial permeability transition pore to trigger necrosis Cell 149 2012 1536
10. J.W. Elrod, and J.D. Molkentin Physiologic functions of cyclophilin D and the mitochondrial permeability transition pore Circ J 77 2013 1111
11. C. Piot, P. Croisille, and P. Staat Effect of cyclosporine on reperfusion injury in acute myocardial infarction N Engl J Med 359 2008 473
12. R.S. Gill, D.L. Bigam, and P.Y. Cheung The role of cyclosporine in the treatment of myocardial reperfusion injury Shock 37 2012 341
13. B. Tharakan, J.G. Holder-Haynes, F.A. Hunter, W.R. Smythe, and E.W. Childs Cyclosporine A prevents vascular hyperpermeability after hemorrhagic shock by inhibiting apoptotic signaling J Trauma 66 2009 1033
14. R. Song, H. Bian, X. Wang, X. Huang, and K.S. Zhao Mitochondrial injury underlies hyporeactivity of arterial smooth muscle in severe shock Am J Hypertens 24 2011 45
15. C. Sapet, S. Simoncini, and B. Loriod Thrombin-induced endothelial microparticle generation: identification of a novel pathway involving ROCK-II activation by caspase-2 Blood 108 2006 1868
16. A. Agudo-López, B.G. Miguel, I. Fernández, and A.M. Martínez Role of protein kinase C and mitochondrial permeability transition pore in the neuroprotective effect of ceramide in ischemia-induced cell death FEBS Lett 585 2011 99
17. G.M. Yang, T. Li, J. Xu, and L.M. Liu PKC plays an important mediated effect in arginine vasopressin induced restoration of vascular responsiveness and calcium sensitization following hemorrhagic shock in rats Eur J Pharmacol 628 2010 148
18. G.M. Yang, T. Li, J. Xu, X.Y. Peng, and L.M. Liu Mitogen-activated protein kinases regulate vascular reactivity after hemorrhagic shock through myosin light chain phosphorylation pathway J Trauma Acute Care Surg 74 2013 1033
19. K.A. Webster, D. Discher, and N.H. Bishopric Induction and nuclear accumulation of Fos and Jun proto-oncogenes in hypoxic cardiac myocytes J Biol Chem 268 1993 16852
20. L. Liu, K. Tian, Y. Zhu, X. Ding, and T. Li δ opioid receptor antagonist, ICI 174,864, is suitable for the early treatment of uncontrolled hemorrhagic shock in rats Anesthesiology 119 2013 379
21. G.M. Yang, J. Xu, T. Li, J. Ming, W. Chen, and L.M. Liu Role of V1a receptor in AVP-induced restoration of vascular hyporeactivity and its relationship to MLCP-MLC20 phosphorylation pathway J Surg Res 161 2010 312
22. R.A. Jones, A. Smail, and M.R. Wilson Detecting mitochondrial permeability transition by confocal imaging of intact cells pinocytically loaded with calcein Eur J Biochem 269 2002 3990
23. E.J. Griffiths, and A.P. Halestrap Mitochondrial non-specific pores remain closed during cardiac ischaemia, but open upon reperfusion Biochem J 307 1995 93
24. C. Hierholzer, J.M. Menezes, A. Ungeheuer, T.R. Billiar, D.J. Tweardy, and B.G. Harbrecht A nitric oxide scavenger protects against pulmonary inflammation following hemorrhagic shock Shock 17 2002 98
25. 2+-induced large-amplitude swelling of liver and heart mitochondria by cyclosporin is probably caused by the inhibitor binding to mitochondrial-matrix peptidyl-prolyl cis-trans isomerase and preventing it interacting with the adenine nucleotide translocase Biochem J 268 1990 153
26. C.U. Niemann, M. Saeed, and H. Akbari Close association between the reduction in myocardial energy metabolism and infarct size: dose-response assessment of cyclosporine J Pharmacol Exp Ther 302 2002 1123
27. M. Crompton, H. Ellinger, and A. Costi Inhibition by cyclosporine A of a Ca2+-dependent pore in heart mitochondria activated by inorganic phosphate and oxidative stress Biochem J 255 1998 357
28. J.H. Hwang, J.H. Lee, and K.H. Lee Cyclosporine A attenuates hypoxic-ischemic brain injury in newborn rats Brain Res 1359 2010 208
29. X. Wang, R. Song, Y. Chen, M. Zhao, and K.S. Zhao Polydatin - a new mitochondria protector for acute severe hemorrhagic shock treatment Expert Opin Investig Drugs 22 2013 169
30. L.M. Liu, and M.A. Dubick Hemorrhagic shock-induced vascular hyporeactivity in the rat: relationship to gene expression of nitric oxide synthase, endothelin-1, and select cytokines in corresponding organs J Surg Res 125 2005 128
31. D.W. Landry, H.R. Levin, and E.M. Gallant Vasopressin pressor hypersensitivity in vasodilatory septic shock Crit Care Med 25 1997 1279
32. E. Amin, B.N. Dubey, and S.C. Zhang Rho-kinase: regulation, (dys)function, and inhibition Biol Chem 394 2013 1399
33. D. Mochly-Rosen, K. Das, and K.V. Grimes Protein kinase C, an elusive therapeutic target? Nat Rev Drug Discov 11 2012 937
34. T. Li, Y. Fang, and Y. Zhu A small dose of arginine vasopressin in combination with norepinephrine is a good early treatment for uncontrolled hemorrhagic shock after hemostasis J Surg Res 169 2011 76
35. J. Xu, T. Li, G. Yang, and L. Liu Pinacidil pretreatment improves vascular reactivity after shock through PKCα and PKCε in rats J Cardiovasc Pharmacol 59 2012 514