Zinc as chaperone-mimicking agent for retardation of amyloid β peptide fibril formation

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 17, 2015, Pages 5407-5412

  Abelein, Axel ^a   Gräslund, Astrid ^a   Danielsson, Jens ^a  

^a STOCKHOLM UNIVERSITY   (Sweden)

Author keywords

Aggregation kinetics; Alzheimer's disease; Amyloid beta peptide; NMR relaxation; Zinc ion interactions

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN[1-40]; MONOMER; ZINC ION; AMYLOID BETA PROTEIN; CHAPERONE; PEPTIDE FRAGMENT; PROTEIN AGGREGATE; ZINC;

AMINO TERMINAL SEQUENCE; APPARENT DISSOCIATION CONSTANT; ARTICLE; CONCEPTUAL FRAMEWORK; DRUG PROTEIN BINDING; HETERONUCLEAR SINGLE QUANTUM COHERENCE; INFRARED SPECTROSCOPY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN FOLDING; QUANTITATIVE ANALYSIS; RNA TRANSLATION; THERMODYNAMICS; ALZHEIMER DISEASE; CHEMICAL MODEL; CHEMISTRY; HUMAN; KINETICS; METABOLISM; PATHOLOGY; PROTEIN TERTIARY STRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; HUMANS; KINETICS; MODELS, CHEMICAL; MOLECULAR CHAPERONES; PEPTIDE FRAGMENTS; PROTEIN AGGREGATES; PROTEIN STRUCTURE, TERTIARY; ZINC;

EID: 84928580256     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1421961112     Document Type: Article

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