-
1
-
-
84883098233
-
Cholera, 2012
-
World Health Organization (WHO). 2013. Cholera, 2012. Wkly Epidemiol Rec 88:321-334.
-
(2013)
Wkly Epidemiol Rec
, vol.88
, pp. 321-334
-
-
-
2
-
-
84863288224
-
The global burden of cholera
-
Ali M, Lopez AL, You YA, Kim YE, Sah B, Maskery B, Clemens J. 2012. The global burden of cholera. Bull World Health Organ 90:209-218A. http://dx.doi.org/10.2471/BLT.11.093427.
-
(2012)
Bull World Health Organ
, vol.90
, pp. 209-218A
-
-
Ali, M.1
Lopez, A.L.2
You, Y.A.3
Kim, Y.E.4
Sah, B.5
Maskery, B.6
Clemens, J.7
-
3
-
-
0023700080
-
Characterization of the Vibrio cholerae ToxR regulon: identification of novel genes involved in intestinal colonization
-
Peterson KM, Mekalanos JJ. 1988. Characterization of the Vibrio cholerae ToxR regulon: identification of novel genes involved in intestinal colonization. Infect Immun 56:2822-2829.
-
(1988)
Infect Immun
, vol.56
, pp. 2822-2829
-
-
Peterson, K.M.1
Mekalanos, J.J.2
-
4
-
-
0030885341
-
Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli
-
Skorupski K, Taylor RK. 1997. Control of the ToxR virulence regulon in Vibrio cholerae by environmental stimuli. Mol Microbiol 25:1003-1009. http://dx.doi.org/10.1046/j.1365-2958.1997.5481909.x.
-
(1997)
Mol Microbiol
, vol.25
, pp. 1003-1009
-
-
Skorupski, K.1
Taylor, R.K.2
-
5
-
-
0031930690
-
TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae
-
Häse CC, Mekalanos JJ. 1998. TcpP protein is a positive regulator of virulence gene expression in Vibrio cholerae. Proc Natl Acad Sci U S A 95:730-734. http://dx.doi.org/10.1073/pnas.95.2.730.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 730-734
-
-
Häse, C.C.1
Mekalanos, J.J.2
-
6
-
-
0028027746
-
Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae
-
Higgins DE, DiRita VJ. 1994. Transcriptional control of toxT, a regulatory gene in the ToxR regulon of Vibrio cholerae. Mol Microbiol 14:17-29. http://dx.doi.org/10.1111/j.1365-2958.1994.tb01263.x.
-
(1994)
Mol Microbiol
, vol.14
, pp. 17-29
-
-
Higgins, D.E.1
Dirita, V.J.2
-
7
-
-
0033815224
-
The Vibrio cholerae ToxR/TcpP/ToxT virulence cascade: distinct roles for two membrane-localized transcriptional activators on a single promoter
-
Krukonis ES, Yu RR, Dirita VJ. 2000. The Vibrio cholerae ToxR/TcpP/ToxT virulence cascade: distinct roles for two membrane-localized transcriptional activators on a single promoter. Mol Microbiol 38:67-84. http://dx.doi.org/10.1046/j.1365-2958.2000.02111.x.
-
(2000)
Mol Microbiol
, vol.38
, pp. 67-84
-
-
Krukonis, E.S.1
Yu, R.R.2
Dirita, V.J.3
-
8
-
-
0032939638
-
Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio cholerae
-
Yu RR, DiRita VJ. 1999. Analysis of an autoregulatory loop controlling ToxT, cholera toxin, and toxin-coregulated pilus production in Vibrio cholerae. J Bacteriol 181:2584-2592.
-
(1999)
J Bacteriol
, vol.181
, pp. 2584-2592
-
-
Yu, R.R.1
Dirita, V.J.2
-
9
-
-
0036786854
-
Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter
-
Hulbert RR, Taylor RK. 2002. Mechanism of ToxT-dependent transcriptional activation at the Vibrio cholerae tcpA promoter. J Bacteriol 184:5533-5544. http://dx.doi.org/10.1128/JB.184.20.5533-5544.2002.
-
(2002)
J Bacteriol
, vol.184
, pp. 5533-5544
-
-
Hulbert, R.R.1
Taylor, R.K.2
-
10
-
-
0028061282
-
Promoter structure, promoter recognition, and transcription activation in prokaryotes
-
Busby S, Ebright RH. 1994. Promoter structure, promoter recognition, and transcription activation in prokaryotes. Cell 79:743-746. http://dx.doi.org/10.1016/0092-8674(94)90063-9.
-
(1994)
Cell
, vol.79
, pp. 743-746
-
-
Busby, S.1
Ebright, R.H.2
-
11
-
-
78649586895
-
The Vibrio cholerae virulence regulatory cascade controls glucose uptake through activation of TarA, a small regulatory RNA
-
Richard AL, Withey JH, Beyhan S, Yildiz F, DiRita VJ. 2010. The Vibrio cholerae virulence regulatory cascade controls glucose uptake through activation of TarA, a small regulatory RNA. Mol Microbiol 78:1171-1181. http://dx.doi.org/10.1111/j.1365-2958.2010.07397.x.
-
(2010)
Mol Microbiol
, vol.78
, pp. 1171-1181
-
-
Richard, A.L.1
Withey, J.H.2
Beyhan, S.3
Yildiz, F.4
Dirita, V.J.5
-
12
-
-
18444417712
-
Activation of both acfA and acfD transcription by Vibrio cholerae ToxT requires binding to two centrally located DNA sites in an inverted repeat conformation
-
Withey JH, DiRita VJ. 2005. Activation of both acfA and acfD transcription by Vibrio cholerae ToxT requires binding to two centrally located DNA sites in an inverted repeat conformation. Mol Microbiol 56:1062-1077. http://dx.doi.org/10.1111/j.1365-2958.2005.04589.x.
-
(2005)
Mol Microbiol
, vol.56
, pp. 1062-1077
-
-
Withey, J.H.1
Dirita, V.J.2
-
13
-
-
33645471024
-
The toxbox: specific DNA sequence requirements for activation of Vibrio cholerae virulence genes by ToxT
-
Withey JH, DiRita VJ. 2006. The toxbox: specific DNA sequence requirements for activation of Vibrio cholerae virulence genes by ToxT. Mol Microbiol 59:1779-1789. http://dx.doi.org/10.1111/j.1365-2958.2006.05053.x.
-
(2006)
Mol Microbiol
, vol.59
, pp. 1779-1789
-
-
Withey, J.H.1
Dirita, V.J.2
-
14
-
-
0032702739
-
Interdependence of the position and orientation of SoxS binding sites in the transcriptional activation of the class I subset of Escherichia coli superoxide-inducible promoters
-
Wood TI, Griffith KL, Fawcett WP, Jair KW, Schneider TD, Wolf RE, Jr. 1999. Interdependence of the position and orientation of SoxS binding sites in the transcriptional activation of the class I subset of Escherichia coli superoxide-inducible promoters. Mol Microbiol 34:414-430. http://dx.doi.org/10.1046/j.1365-2958.1999.01598.x.
-
(1999)
Mol Microbiol
, vol.34
, pp. 414-430
-
-
Wood, T.I.1
Griffith, K.L.2
Fawcett, W.P.3
Jair, K.W.4
Schneider, T.D.5
Wolf, R.E.6
-
15
-
-
79960967875
-
A genome-wide approach to discovery of small RNAs involved in regulation of virulence in Vibrio cholerae
-
Bradley ES, Bodi K, Ismail AM, Camilli A. 2011. A genome-wide approach to discovery of small RNAs involved in regulation of virulence in Vibrio cholerae. PLoS Pathog 7:e1002126. http://dx.doi.org/10.1371/journal.ppat.1002126.
-
(2011)
PLoS Pathog
, vol.7
, pp. e1002126
-
-
Bradley, E.S.1
Bodi, K.2
Ismail, A.M.3
Camilli, A.4
-
16
-
-
28044437734
-
Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genes
-
Withey JH, Dirita VJ. 2005. Vibrio cholerae ToxT independently activates the divergently transcribed aldA and tagA genes. J Bacteriol 187:7890-7900. http://dx.doi.org/10.1128/JB.187.23.7890-7900.2005.
-
(2005)
J Bacteriol
, vol.187
, pp. 7890-7900
-
-
Withey, J.H.1
Dirita, V.J.2
-
17
-
-
77649246314
-
Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes
-
Lowden MJ, Skorupski K, Pellegrini M, Chiorazzo MG, Taylor RK, Kull FJ. 2010. Structure of Vibrio cholerae ToxT reveals a mechanism for fatty acid regulation of virulence genes. Proc Natl Acad Sci U S A 107:2860-2865. http://dx.doi.org/10.1073/pnas.0915021107.
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 2860-2865
-
-
Lowden, M.J.1
Skorupski, K.2
Pellegrini, M.3
Chiorazzo, M.G.4
Taylor, R.K.5
Kull, F.J.6
-
18
-
-
80051492032
-
N-terminal residues of the Vibrio cholerae virulence regulatory protein ToxT involved in dimerization and modulation by fatty acids
-
Childers BM, Cao X, Weber GG, Demeler B, Hart PJ, Klose KE. 2011. N-terminal residues of the Vibrio cholerae virulence regulatory protein ToxT involved in dimerization and modulation by fatty acids. J Biol Chem 286:28644-28655. http://dx.doi.org/10.1074/jbc. M111.258780.
-
(2011)
J Biol Chem
, vol.286
, pp. 28644-28655
-
-
Childers, B.M.1
Cao, X.2
Weber, G.G.3
Demeler, B.4
Hart, P.J.5
Klose, K.E.6
-
19
-
-
33947164676
-
Identification of residues critical for the function of the Vibrio cholerae virulence regulator ToxT by scanning alanine mutagenesis
-
Childers BM, Weber GG, Prouty MG, Castaneda MM, Peng F, Klose KE. 2007. Identification of residues critical for the function of the Vibrio cholerae virulence regulator ToxT by scanning alanine mutagenesis. J Mol Biol 367:1413-1430. http://dx.doi.org/10.1016/j.jmb.2007.01.061.
-
(2007)
J Mol Biol
, vol.367
, pp. 1413-1430
-
-
Childers, B.M.1
Weber, G.G.2
Prouty, M.G.3
Castaneda, M.M.4
Peng, F.5
Klose, K.E.6
-
20
-
-
27944462141
-
Characterization of functional domains of the Vibrio cholerae virulence regulator ToxT
-
Prouty MG, Osorio CR, Klose KE. 2005. Characterization of functional domains of the Vibrio cholerae virulence regulator ToxT. Mol Microbiol 58:1143-1156. http://dx.doi.org/10.1111/j.1365-2958.2005.04897.x.
-
(2005)
Mol Microbiol
, vol.58
, pp. 1143-1156
-
-
Prouty, M.G.1
Osorio, C.R.2
Klose, K.E.3
-
21
-
-
33847768086
-
Virstatin inhibits dimerization of the transcriptional activator ToxT
-
Shakhnovich EA, Hung DT, Pierson E, Lee K, Mekalanos JJ. 2007. Virstatin inhibits dimerization of the transcriptional activator ToxT. Proc Natl Acad Sci U S A 104:2372-2377. http://dx.doi.org/10.1073/pnas.0611643104.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 2372-2377
-
-
Shakhnovich, E.A.1
Hung, D.T.2
Pierson, E.3
Lee, K.4
Mekalanos, J.J.5
-
22
-
-
27344443267
-
Smallmolecule inhibitor of Vibrio cholerae virulence and intestinal colonization
-
Hung DT, Shakhnovich EA, Pierson E, Mekalanos JJ. 2005. Smallmolecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science 310:670-674. http://dx.doi.org/10.1126/science.1116739.
-
(2005)
Science
, vol.310
, pp. 670-674
-
-
Hung, D.T.1
Shakhnovich, E.A.2
Pierson, E.3
Mekalanos, J.J.4
-
23
-
-
77955931762
-
The LysR-type virulence activator AphB regulates the expression of genes in Vibrio cholerae in response to lowpHand anaerobiosis
-
Kovacikova G, Lin W, Skorupski K. 2010. The LysR-type virulence activator AphB regulates the expression of genes in Vibrio cholerae in response to lowpHand anaerobiosis. J Bacteriol 192:4181-4191. http://dx.doi.org/10.1128/JB.00193-10.
-
(2010)
J Bacteriol
, vol.192
, pp. 4181-4191
-
-
Kovacikova, G.1
Lin, W.2
Skorupski, K.3
-
24
-
-
0031029971
-
Bile affects production of virulence factors and motility of Vibrio cholerae
-
Gupta S, Chowdhury R. 1997. Bile affects production of virulence factors and motility of Vibrio cholerae. Infect Immun 65:1131-1134.
-
(1997)
Infect Immun
, vol.65
, pp. 1131-1134
-
-
Gupta, S.1
Chowdhury, R.2
-
25
-
-
34147179428
-
Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of Vibrio cholerae
-
Chatterjee A, Dutta PK, Chowdhury R. 2007. Effect of fatty acids and cholesterol present in bile on expression of virulence factors and motility of Vibrio cholerae. Infect Immun 75:1946-1953. http://dx.doi.org/10.1128/IAI.01435-06.
-
(2007)
Infect Immun
, vol.75
, pp. 1946-1953
-
-
Chatterjee, A.1
Dutta, P.K.2
Chowdhury, R.3
-
26
-
-
69049095025
-
Bicarbonate induces Vibrio cholerae virulence gene expression by enhancing ToxT activity
-
Abuaita BH, Withey JH. 2009. Bicarbonate induces Vibrio cholerae virulence gene expression by enhancing ToxT activity. Infect Immun 77:4111-4120. http://dx.doi.org/10.1128/IAI.00409-09.
-
(2009)
Infect Immun
, vol.77
, pp. 4111-4120
-
-
Abuaita, B.H.1
Withey, J.H.2
-
27
-
-
0032987096
-
Environmental signals modulate ToxT-dependent virulence factor expression in Vibrio cholerae
-
Schuhmacher DA, Klose KE. 1999. Environmental signals modulate ToxT-dependent virulence factor expression in Vibrio cholerae. J Bacteriol 181:1508-1514.
-
(1999)
J Bacteriol
, vol.181
, pp. 1508-1514
-
-
Schuhmacher, D.A.1
Klose, K.E.2
-
28
-
-
0034967448
-
Vibrio cholerae tolC is required for bile resistance and colonization
-
Bina JE, Mekalanos JJ. 2001. Vibrio cholerae tolC is required for bile resistance and colonization. Infect Immun 69:4681-4685. http://dx.doi.org/10.1128/IAI.69.7.4681-4685.2001.
-
(2001)
Infect Immun
, vol.69
, pp. 4681-4685
-
-
Bina, J.E.1
Mekalanos, J.J.2
-
29
-
-
0034730163
-
Altered expression of the ToxR-regulated porins OmpU and OmpT diminishes Vibrio cholerae bile resistance, virulence factor expression, and intestinal colonization
-
Provenzano D, Klose KE. 2000. Altered expression of the ToxR-regulated porins OmpU and OmpT diminishes Vibrio cholerae bile resistance, virulence factor expression, and intestinal colonization. Proc Natl Acad Sci U S A 97:10220-10224. http://dx.doi.org/10.1073/pnas.170219997.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10220-10224
-
-
Provenzano, D.1
Klose, K.E.2
-
30
-
-
14544302240
-
Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner
-
Hung DT, Mekalanos JJ. 2005. Bile acids induce cholera toxin expression in Vibrio cholerae in a ToxT-independent manner. Proc Natl Acad Sci U S A 102:3028-3033. http://dx.doi.org/10.1073/pnas.0409559102.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3028-3033
-
-
Hung, D.T.1
Mekalanos, J.J.2
-
31
-
-
4944223116
-
Effect of bile on the cell surface permeability barrier and efflux system of Vibrio cholerae
-
Chatterjee A, Chaudhuri S, Saha G, Gupta S, Chowdhury R. 2004. Effect of bile on the cell surface permeability barrier and efflux system of Vibrio cholerae. J Bacteriol 186:6809-6814. http://dx.doi.org/10.1128/JB.186.20.6809-6814.2004.
-
(2004)
J Bacteriol
, vol.186
, pp. 6809-6814
-
-
Chatterjee, A.1
Chaudhuri, S.2
Saha, G.3
Gupta, S.4
Chowdhury, R.5
-
32
-
-
84917711113
-
Bicarbonate increases binding affinity of Vibrio cholerae ToxT to virulence gene promoters
-
Thomson JJ, Withey JH. 2014. Bicarbonate increases binding affinity of Vibrio cholerae ToxT to virulence gene promoters. J Bacteriol 196:3872-3880. http://dx.doi.org/10.1128/JB.01824-14.
-
(2014)
J Bacteriol
, vol.196
, pp. 3872-3880
-
-
Thomson, J.J.1
Withey, J.H.2
-
33
-
-
0003785155
-
Experiments in molecular genetics
-
Cold Spring Harbor Laboratory, Cold Spring Harbor, NY
-
Miller JH. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
-
(1972)
-
-
Miller, J.H.1
-
34
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method
-
Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) method. Methods 25:402-408. http://dx.doi.org/10.1006/meth.2001.1262.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
35
-
-
84868312953
-
Identification and characterization of the functional toxboxes in the Vibrio cholerae cholera toxin promoter
-
Dittmer JB, Withey JH. 2012. Identification and characterization of the functional toxboxes in the Vibrio cholerae cholera toxin promoter. J Bacteriol 194:5255-5263. http://dx.doi.org/10.1128/JB.00952-12.
-
(2012)
J Bacteriol
, vol.194
, pp. 5255-5263
-
-
Dittmer, J.B.1
Withey, J.H.2
-
36
-
-
0023258585
-
Fatty acid composition of phospholipids in bile in man: promoting effect of deoxycholate on arachidonate
-
van Berge Henegouwen GP, van der Werf SD, Ruben AT. 1987. Fatty acid composition of phospholipids in bile in man: promoting effect of deoxycholate on arachidonate. Clin Chim Acta 165:27-37. http://dx.doi.org/10.1016/0009-8981(87)90215-4.
-
(1987)
Clin Chim Acta
, vol.165
, pp. 27-37
-
-
Van Berge Henegouwen, G.P.1
Van der Werf, S.D.2
Ruben, A.T.3
|