-
1
-
-
0025963146
-
Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein
-
Cooney EL, Collier AC, Greenberg PD, Coombs RW, Zarling J, Arditti DE, Hoffman MC, Hu SL, Corey L. 1991. Safety of and immunological response to a recombinant vaccinia virus vaccine expressing HIV envelope glycoprotein. Lancet 337:567-572. http://dx.doi.org/10.1016/0140-6736(91)91636-9.
-
(1991)
Lancet
, vol.337
, pp. 567-572
-
-
Cooney, E.L.1
Collier, A.C.2
Greenberg, P.D.3
Coombs, R.W.4
Zarling, J.5
Arditti, D.E.6
Hoffman, M.C.7
Hu, S.L.8
Corey, L.9
-
2
-
-
84940611885
-
A national multicenter phase 2 study of prostate-specific antigen (PSA) pox virus vaccine with sequential androgen ablation therapy in patients with PSA progression: ECOG 9802
-
18 December
-
DiPaola RS, Chen Y, Bubley GJ, Stein MN, Hahn NM, Carducci MA, Lattime EC, Gulley JL, Arlen PM, Butterfield LH, Wilding G. 18 December 2014. A national multicenter phase 2 study of prostate-specific antigen (PSA) pox virus vaccine with sequential androgen ablation therapy in patients with PSA progression: ECOG 9802. Eur Urol http://dx.doi.org/10.1016/j.eururo.2014.12.010.
-
(2014)
Eur Urol
-
-
DiPaola, R.S.1
Chen, Y.2
Bubley, G.J.3
Stein, M.N.4
Hahn, N.M.5
Carducci, M.A.6
Lattime, E.C.7
Gulley, J.L.8
Arlen, P.M.9
Butterfield, L.H.10
Wilding, G.11
-
3
-
-
3042681334
-
Vaccinia as a vector for gene delivery
-
Guo ZS, Bartlett DL. 2004. Vaccinia as a vector for gene delivery. Expert Opin Biol Ther 4:901-917. http://dx.doi.org/10.1517/14712598.4.6.901.
-
(2004)
Expert Opin Biol Ther
, vol.4
, pp. 901-917
-
-
Guo, Z.S.1
Bartlett, D.L.2
-
4
-
-
84882850376
-
Reflections on the early development of poxvirus vectors
-
Moss B. 2013. Reflections on the early development of poxvirus vectors. Vaccine 31:4220-4222. http://dx.doi.org/10.1016/j.vaccine.2013.03.042.
-
(2013)
Vaccine
, vol.31
, pp. 4220-4222
-
-
Moss, B.1
-
5
-
-
80052406557
-
Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans
-
Breitbach CJ, Burke J, Jonker D, Stephenson J, Haas AR, Chow LQ, Nieva J, Hwang TH, Moon A, Patt R, Pelusio A, Le Boeuf F, Burns J, Evgin L, De Silva N, Cvancic S, Robertson T, Je JE, Lee YS, Parato K, Diallo JS, Fenster A, Daneshmand M, Bell JC, Kirn DH. 2011. Intravenous delivery of a multi-mechanistic cancer-targeted oncolytic poxvirus in humans. Nature 477:99-102. http://dx.doi.org/10.1038/nature10358.
-
(2011)
Nature
, vol.477
, pp. 99-102
-
-
Breitbach, C.J.1
Burke, J.2
Jonker, D.3
Stephenson, J.4
Haas, A.R.5
Chow, L.Q.6
Nieva, J.7
Hwang, T.H.8
Moon, A.9
Patt, R.10
Pelusio, A.11
Le Boeuf, F.12
Burns, J.13
Evgin, L.14
De Silva, N.15
Cvancic, S.16
Robertson, T.17
Je, J.E.18
Lee, Y.S.19
Parato, K.20
Diallo, J.S.21
Fenster, A.22
Daneshmand, M.23
Bell, J.C.24
Kirn, D.H.25
more..
-
6
-
-
84921063739
-
A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer
-
Chard L, Maniati E, Wang P, Zhang Z, Gao D, Wang J, Cao F, Ahmed J, Khouri ME, Hughes J, Wang S, Li X, Denes B, Fodor I, Hagemann T, Lemoine NR, Wang Y. 2015. A vaccinia virus armed with interleukin-10 is a promising therapeutic agent for treatment of murine pancreatic cancer. Clin Cancer Res 21:405-416. http://dx.doi.org/10.1158/1078-0432.CCR-14-0464.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 405-416
-
-
Chard, L.1
Maniati, E.2
Wang, P.3
Zhang, Z.4
Gao, D.5
Wang, J.6
Cao, F.7
Ahmed, J.8
Khouri, M.E.9
Hughes, J.10
Wang, S.11
Li, X.12
Denes, B.13
Fodor, I.14
Hagemann, T.15
Lemoine, N.R.16
Wang, Y.17
-
7
-
-
84875225339
-
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
-
Heo J, Reid T, Ruo L, Breitbach CJ, Rose S, Bloomston M, Cho M, Lim HY, Chung HC, Kim CW, Burke J, Lencioni R, Hickman T, Moon A, Lee YS, Kim MK, Daneshmand M, Dubois K, Longpre L, Ngo M, Rooney C, Bell JC, Rhee BG, Patt R, Hwang TH, Kirn DH. 2013. Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med 19:329-336. http://dx.doi.org/10.1038/nm.3089.
-
(2013)
Nat Med
, vol.19
, pp. 329-336
-
-
Heo, J.1
Reid, T.2
Ruo, L.3
Breitbach, C.J.4
Rose, S.5
Bloomston, M.6
Cho, M.7
Lim, H.Y.8
Chung, H.C.9
Kim, C.W.10
Burke, J.11
Lencioni, R.12
Hickman, T.13
Moon, A.14
Lee, Y.S.15
Kim, M.K.16
Daneshmand, M.17
Dubois, K.18
Longpre, L.19
Ngo, M.20
Rooney, C.21
Bell, J.C.22
Rhee, B.G.23
Patt, R.24
Hwang, T.H.25
Kirn, D.H.26
more..
-
8
-
-
70350376151
-
Lister strain of vaccinia virus armed with endostatinangiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer
-
Tysome JR, Briat A, Alusi G, Cao F, Gao D, Yu J, Wang P, Yang S, Dong Z, Wang S, Deng L, Francis J, Timiryasova T, Fodor I, Lemoine NR, Wang Y. 2009. Lister strain of vaccinia virus armed with endostatinangiostatin fusion gene as a novel therapeutic agent for human pancreatic cancer. Gene Ther 16:1223-1233. http://dx.doi.org/10.1038/gt.2009.74.
-
(2009)
Gene Ther
, vol.16
, pp. 1223-1233
-
-
Tysome, J.R.1
Briat, A.2
Alusi, G.3
Cao, F.4
Gao, D.5
Yu, J.6
Wang, P.7
Yang, S.8
Dong, Z.9
Wang, S.10
Deng, L.11
Francis, J.12
Timiryasova, T.13
Fodor, I.14
Lemoine, N.R.15
Wang, Y.16
-
9
-
-
61949147263
-
The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility
-
Weisswange I, Newsome TP, Schleich S, Way M. 2009. The rate of N-WASP exchange limits the extent of ARP2/3-complex-dependent actin-based motility. Nature 458:87-91. http://dx.doi.org/10.1038/nature07773.
-
(2009)
Nature
, vol.458
, pp. 87-91
-
-
Weisswange, I.1
Newsome, T.P.2
Schleich, S.3
Way, M.4
-
10
-
-
0025302978
-
Transient dominant selection of recombinant vaccinia viruses
-
Falkner FG, Moss B. 1990. Transient dominant selection of recombinant vaccinia viruses. J Virol 64:3108-3111.
-
(1990)
J Virol
, vol.64
, pp. 3108-3111
-
-
Falkner, F.G.1
Moss, B.2
-
11
-
-
0021345626
-
General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes
-
Mackett M, Smith GL, Moss B. 1984. General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes. J Virol 49:857-864.
-
(1984)
J Virol
, vol.49
, pp. 857-864
-
-
Mackett, M.1
Smith, G.L.2
Moss, B.3
-
12
-
-
0037126074
-
Cloning the vaccinia virus genome as a bacterial artificial chromosome in Escherichia coli and recovery of infectious virus in mammalian cells
-
Domi A, Moss B. 2002. Cloning the vaccinia virus genome as a bacterial artificial chromosome in Escherichia coli and recovery of infectious virus in mammalian cells. Proc Natl Acad Sci USA 99:12415-12420. http://dx.doi.org/10.1073/pnas.192420599.
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 12415-12420
-
-
Domi, A.1
Moss, B.2
-
13
-
-
0020071816
-
Molecular genetics of vaccinia virus: demonstration of marker rescue
-
Nakano E, Panicali D, Paoletti E. 1982. Molecular genetics of vaccinia virus: demonstration of marker rescue. Proc Natl Acad Sci USA 79:1593-1596. http://dx.doi.org/10.1073/pnas.79.5.1593.
-
(1982)
Proc Natl Acad Sci USA
, vol.79
, pp. 1593-1596
-
-
Nakano, E.1
Panicali, D.2
Paoletti, E.3
-
14
-
-
0036267740
-
Identification of genes that are associated with DNA repeats in prokaryotes
-
Jansen R, Embden JD, Gaastra W, Schouls LM. 2002. Identification of genes that are associated with DNA repeats in prokaryotes. Mol Microbiol 43:1565-1575. http://dx.doi.org/10.1046/j.1365-2958.2002.02839.x.
-
(2002)
Mol Microbiol
, vol.43
, pp. 1565-1575
-
-
Jansen, R.1
Embden, J.D.2
Gaastra, W.3
Schouls, L.M.4
-
15
-
-
49649114086
-
Small CRISPR RNAs guide antiviral defense in prokaryotes
-
Brouns SJ, Jore MM, Lundgren M, Westra ER, Slijkhuis RJ, Snijders AP, Dickman MJ, Makarova KS, Koonin EV, van der Oost J. 2008. Small CRISPR RNAs guide antiviral defense in prokaryotes. Science 321: 960-964. http://dx.doi.org/10.1126/science.1159689.
-
(2008)
Science
, vol.321
, pp. 960-964
-
-
Brouns, S.J.1
Jore, M.M.2
Lundgren, M.3
Westra, E.R.4
Slijkhuis, R.J.5
Snijders, A.P.6
Dickman, M.J.7
Makarova, K.S.8
Koonin, E.V.9
van der Oost, J.10
-
16
-
-
68249102788
-
CRISPR-based adaptive and heritable immunity in prokaryotes
-
van der Oost J, Jore MM, Westra ER, Lundgren M, Brouns SJ. 2009. CRISPR-based adaptive and heritable immunity in prokaryotes. Trends Biochem Sci 34:401-407. http://dx.doi.org/10.1016/j.tibs.2009.05.002.
-
(2009)
Trends Biochem Sci
, vol.34
, pp. 401-407
-
-
van der Oost, J.1
Jore, M.M.2
Westra, E.R.3
Lundgren, M.4
Brouns, S.J.5
-
17
-
-
84873729095
-
Multiplex genome engineering using CRISPR/Cas systems
-
Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. 2013. Multiplex genome engineering using CRISPR/Cas systems. Science 339:819-823. http://dx.doi.org/10.1126/science.1231143.
-
(2013)
Science
, vol.339
, pp. 819-823
-
-
Cong, L.1
Ran, F.A.2
Cox, D.3
Lin, S.4
Barretto, R.5
Habib, N.6
Hsu, P.D.7
Wu, X.8
Jiang, W.9
Marraffini, L.A.10
Zhang, F.11
-
18
-
-
84865070369
-
Aprogrammabledual-RNA-guidedDNAendonuclease in adaptive bacterial immunity
-
Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E. 2012. Aprogrammabledual-RNA-guidedDNAendonuclease in adaptive bacterial immunity. Science 337:816-821. http://dx.doi.org/10.1126/science.1225829.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
19
-
-
84894081986
-
Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos
-
Niu Y, Shen B, Cui Y, Chen Y, Wang J, Wang L, Kang Y, Zhao X, Si W, Li W, Xiang AP, Zhou J, Guo X, Bi Y, Si C, Hu B, Dong G, Wang H, Zhou Z, Li T, Tan T, Pu X, Wang F, Ji S, Zhou Q, Huang X, Ji W, Sha J. 2014. Generation of gene-modified cynomolgus monkey via Cas9/RNA-mediated gene targeting in one-cell embryos. Cell 156:836-843. http://dx.doi.org/10.1016/j.cell.2014.01.027.
-
(2014)
Cell
, vol.156
, pp. 836-843
-
-
Niu, Y.1
Shen, B.2
Cui, Y.3
Chen, Y.4
Wang, J.5
Wang, L.6
Kang, Y.7
Zhao, X.8
Si, W.9
Li, W.10
Xiang, A.P.11
Zhou, J.12
Guo, X.13
Bi, Y.14
Si, C.15
Hu, B.16
Dong, G.17
Wang, H.18
Zhou, Z.19
Li, T.20
Tan, T.21
Pu, X.22
Wang, F.23
Ji, S.24
Zhou, Q.25
Huang, X.26
Ji, W.27
Sha, J.28
more..
-
20
-
-
84902095353
-
Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype
-
Yin H, Xue W, Chen S, Bogorad RL, Benedetti E, Grompe M, Koteliansky V, Sharp PA, Jacks T, Anderson DG. 2014. Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype. Nat Biotechnol 32:551-553. http://dx.doi.org/10.1038/nbt.2884.
-
(2014)
Nat Biotechnol
, vol.32
, pp. 551-553
-
-
Yin, H.1
Xue, W.2
Chen, S.3
Bogorad, R.L.4
Benedetti, E.5
Grompe, M.6
Koteliansky, V.7
Sharp, P.A.8
Jacks, T.9
Anderson, D.G.10
-
21
-
-
84877707375
-
One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering
-
Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. 2013. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell 153: 910-918. http://dx.doi.org/10.1016/j.cell.2013.04.025.
-
(2013)
Cell
, vol.153
, pp. 910-918
-
-
Wang, H.1
Yang, H.2
Shivalila, C.S.3
Dawlaty, M.M.4
Cheng, A.W.5
Zhang, F.6
Jaenisch, R.7
-
22
-
-
84901648428
-
High-efficiency targeted editing of large viral genomes by RNA-guided nucleases
-
Bi Y, Sun L, Gao D, Ding C, Li Z, Li Y, Cun W, Li Q. 2014. High-efficiency targeted editing of large viral genomes by RNA-guided nucleases. PLoS Pathog 10:e1004090. http://dx.doi.org/10.1371/journal.ppat.1004090.
-
(2014)
PLoS Pathog
, vol.10
-
-
Bi, Y.1
Sun, L.2
Gao, D.3
Ding, C.4
Li, Z.5
Li, Y.6
Cun, W.7
Li, Q.8
-
23
-
-
84928559890
-
A novel tumour selective oncolytic vaccinia virus lacking the N1L gene enhances the anti-tumour immune response when used as an anticancer therapeutic
-
Ahmed JY, Yuan M, Li YN, Chu YC, Shi HL, Chard L, Alusi G, Lemoine N, Wang Y. 2014. A novel tumour selective oncolytic vaccinia virus lacking the N1L gene enhances the anti-tumour immune response when used as an anticancer therapeutic. Mol Ther 22:S248-S249.
-
(2014)
Mol Ther
, vol.22
, pp. S248-S249
-
-
Ahmed, J.Y.1
Yuan, M.2
Li, Y.N.3
Chu, Y.C.4
Shi, H.L.5
Chard, L.6
Alusi, G.7
Lemoine, N.8
Wang, Y.9
-
24
-
-
0036328156
-
The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence
-
Bartlett N, Symons JA, Tscharke DC, Smith GL. 2002. The vaccinia virus N1L protein is an intracellular homodimer that promotes virulence. J Gen Virol 83(Pt 8):1965-1976.
-
(2002)
J Gen Virol
, vol.83
, pp. 1965-1976
-
-
Bartlett, N.1
Symons, J.A.2
Tscharke, D.C.3
Smith, G.L.4
-
25
-
-
15044342029
-
Lack of N1L gene expression results in a significant decrease of vaccinia virus replication in mouse brain
-
Billings B, Smith SA, Zhang Z, Lahiri DK, Kotwal GJ. 2004. Lack of N1L gene expression results in a significant decrease of vaccinia virus replication in mouse brain. Ann N Y Acad Sci 1030:297-302. http://dx.doi.org/10.1196/annals.1329.037.
-
(2004)
Ann N Y Acad Sci
, vol.1030
, pp. 297-302
-
-
Billings, B.1
Smith, S.A.2
Zhang, Z.3
Lahiri, D.K.4
Kotwal, G.J.5
-
26
-
-
84884233525
-
Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C
-
Perdiguero B, Gomez CE, Di Pilato M, Sorzano CO, Delaloye J, Roger T, Calandra T, Pantaleo G, Esteban M. 2013. Deletion of the vaccinia virus gene A46R, encoding for an inhibitor of TLR signalling, is an effective approach to enhance the immunogenicity in mice of the HIV/AIDS vaccine candidate NYVAC-C. PLoS One 8:e74831. http://dx.doi.org/10.1371/journal.pone.0074831.
-
(2013)
PLoS One
, vol.8
-
-
Perdiguero, B.1
Gomez, C.E.2
Di Pilato, M.3
Sorzano, C.O.4
Delaloye, J.5
Roger, T.6
Calandra, T.7
Pantaleo, G.8
Esteban, M.9
-
27
-
-
17144366260
-
Vaccinia virus proteinA46Rtargets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence
-
Stack J, Haga IR, Schroder M, Bartlett NW, Maloney G, Reading PC, Fitzgerald KA, Smith GL, Bowie AG. 2005. Vaccinia virus proteinA46Rtargets multiple Toll-like-interleukin-1 receptor adaptors and contributes to virulence. J ExpMed 201:1007-1018. http://dx.doi.org/10.1084/jem.20041442.
-
(2005)
J ExpMed
, vol.201
, pp. 1007-1018
-
-
Stack, J.1
Haga, I.R.2
Schroder, M.3
Bartlett, N.W.4
Maloney, G.5
Reading, P.C.6
Fitzgerald, K.A.7
Smith, G.L.8
Bowie, A.G.9
|