The flavonoid morin from Moraceae induces apoptosis by modulation of Bcl-2 family members and Fas receptor in HCT 116 cells

International Journal of Oncology

Volumn 46, Issue 6, 2015, Pages 2670-2678

  Hyun, Hwang Bo ^a   Lee, Won Sup ^b   Go, Se Il ^b   Nagappan, Arulkumar ^b   Park, Cheol ^a   Han, Min Ho ^c   Hong, Su Hyun ^c   Kim, Gonsup ^d   Kim, Gi Young ^e   Cheong, Jaehun ^f   Ryu, Chung Ho ^d   Shin, Sung Chul ^d   Choi, Yung Hyun ^a,c  

^a Dong Eui University   (South Korea)

^b Gyeongsang National University School of Medicine   (South Korea)

^c Dong Eui University   (South Korea)

^d Gyeongsang National University   (South Korea)

^e Jeju National University   (South Korea)

^f Pusan National University   (South Korea)

Author keywords

Bcl 2; Fas receptor; HCT 116 human colon cancer cells; Morin

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ACETYLCYSTEINE; ANTINEOPLASTIC AGENT; CASPASE 3; CASPASE 8; CASPASE 9; CYTOCHROME C; DEATH RECEPTOR 4; DEATH RECEPTOR 5; FAS ANTIGEN; INHIBITOR OF APOPTOSIS PROTEIN 1; MITOGEN ACTIVATED PROTEIN KINASE P38; MORIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROCASPASE 3; PROCASPASE 8; PROCASPASE 9; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BID; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; VOLTAGE DEPENDENT ANION CHANNEL; CASPASE; FLAVONOID; INHIBITOR OF APOPTOSIS PROTEIN;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G1 PHASE; CELL DEATH; CELL MEMBRANE DEPOLARIZATION; CELL PROLIFERATION; CELL SURVIVAL; DNA CONTENT; DNA FRAGMENTATION; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME ACTIVITY; HCT116 CELL LINE; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; MITOCHONDRIAL MEMBRANE POTENTIAL; MORACEAE; MULBERRY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; COLORECTAL NEOPLASMS; DRUG EFFECTS; METABOLISM;

ANTIGENS, CD95; ANTINEOPLASTIC AGENTS; APOPTOSIS; CASPASES; COLORECTAL NEOPLASMS; FLAVONOIDS; HCT116 CELLS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PROTO-ONCOGENE PROTEINS C-BCL-2;

EID: 84928558651     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2015.2967     Document Type: Article

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