Direct neuronal glucose uptake heralds activity-dependent increases in cerebral metabolism

Nature Communications

Volumn 6, Issue , 2015, Pages

  Lundgaard, Iben ^a,b   Li, Baoman ^a,c   Xie, Lulu ^a,b   Kang, Hongyi ^a,b   Sanggaard, Simon ^a,b   Haswell, John D R ^a,b   Sun, Wei ^a,b   Goldman, Siri ^a,b   Blekot, Solomiya ^a,b   Nielsen, Michael ^a,b   Takano, Takahiro ^a,b   Deane, Rashid ^a,b   Nedergaard, Maiken ^a,b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF COPENHAGEN   (Denmark)

^c CHINA MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYGLUCOSE; GLUCOSE; GLYCOLYTIC ENZYME; MESSENGER RNA; ANESTHETIC AGENT; ANTIMETABOLITE; HEXOKINASE; HYPNOTIC SEDATIVE AGENT; KETAMINE; XYLAZINE;

BRAIN; ENZYME ACTIVITY; GLUCOSE; IMAGING METHOD; METABOLISM; NEUROLOGY; RODENT;

ADULT; ANIMAL CELL; ANIMAL TISSUE; ANTIBODY LABELING; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; BLOOD BRAIN BARRIER; BRAIN METABOLISM; BRAIN REGION; BRAIN SLICE; CELL TRANSPORT; CISTERNA MAGNA; CONTROLLED STUDY; ELECTROENCEPHALOGRAM; ENERGY METABOLISM; FLUORESCENCE ACTIVATED CELL SORTING; FUNCTIONAL NEUROIMAGING; GLUCOSE INTAKE; GLUCOSE TRANSPORT; GLYCOLYSIS; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL; NERVE CELL CULTURE; NONHUMAN; PYRAMIDAL NERVE CELL; QUANTITATIVE ANALYSIS; ANIMAL; BRAIN; BRAIN CORTEX; CELL CULTURE; DRUG EFFECTS; GENETICS; METABOLISM; NEAR INFRARED SPECTROSCOPY; PHYSICAL STIMULATION; PROCEDURES; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WAKEFULNESS;

MUS;

ANESTHETICS, DISSOCIATIVE; ANIMALS; ANTIMETABOLITES; ASTROCYTES; BRAIN; CELLS, CULTURED; CEREBRAL CORTEX; DEOXYGLUCOSE; FUNCTIONAL NEUROIMAGING; GLUCOSE; HEXOKINASE; HUMANS; HYPNOTICS AND SEDATIVES; IMMUNOHISTOCHEMISTRY; KETAMINE; MICE; NEURONS; PHYSICAL STIMULATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SPECTROSCOPY, NEAR-INFRARED; WAKEFULNESS; XYLAZINE;

EID: 84928526146     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7807     Document Type: Article

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