The effects of EGb761 on lipopolysaccharide-induced depressive-like behaviour in C57BL/6J mice

Central European Journal of Immunology

Volumn 40, Issue 1, 2015, Pages 11-17

  Zhao, Yuehan ^a   Zhang, Yongdong ^b   Pan, Fang ^a  

^a SHANDONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Qingdao Mental Health Center   (China)

Author keywords

Brain derived neurotrophic factor; Depressive like behaviour; EGb761; Inflammation; Lipopolysaccharide

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GINKGO BILOBA EXTRACT; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DEPRESSION; DRUG EFFECT; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; FORCED SWIM TEST; GINKGO BILOBA; HIPPOCAMPUS; LOCOMOTION; LOW DRUG DOSE; MALE; MOUSE; NEUROPROTECTION; NONHUMAN; OPEN FIELD TEST; SUCROSE PREFERENCE TEST; TAIL SUSPENSION TEST; TISSUE HOMOGENATE; TREATMENT DURATION;

EID: 84928492362     PISSN: 14263912     EISSN: 16444124     Source Type: Journal    
DOI: 10.5114/ceji.2015.49427     Document Type: Article

References (29)

1. Wang YH, Yin LT, Yang H, et al. (2014): Hypoglycemic and anti-depressant effects of Zuogui Jiangtang Jieyu formulation in a model of unpredictable chronic mild stress in rats with diabetes mellitus. Exp Ther Med 8: 281-285.
2. Slavich GM, Irwin MR (2014): From stress to inflammation and major depressive disorder: a social signal transduction theory of depression. Psychol Bull 140: 774-815.
3. Tonelli LH, Holmes A, Postolache TT (2008): Intranasal immune challenge induces sex- dependent depressive-like behavior and cytokine expression in the brain. Europsychopharmacology 33: 1038-1048.
4. Xie W, Cai L, Yu Y, et al. (2014): Activation of brain indoleamine 2,3-dioxygenase contributes to epilepsy-associated depressive-like behavior in rats with chronic temporal lobe epilepsy. J Neuroinflammation 11: doi: 10.1186/1742-2094- 11-41.
5. Chengde Li, Shumei Mao, Yuliang Wang, et al. (2012): Effects of combination therapy of dexamethasone and fluoxetine on levels of interleukin-1β and interleukin-6 in a rat model of asthma with depressive-like behaviors. HealthMED 6: 1998-2003.
6. Raison CL, Capuron L, Miller AH (2006): Cytokines sing the blues: inflammation. And the pathogenesis of depression. Trends Immunol 27: 24-31.
7. Janssen DG1, Caniato RN, Verster JC, et al. (2010): A psychoneuro-immunological review on cytokines involved in antidepressant treatment response. Hum Psychopharmacol 25: 201-215.
8. Beurel E, Harrington LE, Jope RS. (2013): Inflammatory T helper 17 cells promote depression-like behavior in mice. Biol Psychiatry 73: 622-630.
9. Chen Y, Jiang T, Chen P, et al. (2011): Emerging tendency towards autoimmune process in major depressivepatients: a novel insight from Th17 cells. Psychiatry Res 188: 224-230.
10. Chengde Li, Shumei Mao, Hongwei Sun, et al. (2013): Infuences of chronic variable stress on levels of interleukin-17A, IFN-γ and TNF-α in OVA-induced asthmatic rats. HealthMED 7: 2092-2098.
11. Liu Y, Ho RC, Mak A (2012): The role of interleukin (IL)-17 in anxiety and depression of patients with rheumatoid arthritis. Int J Rheum Dis 15: 183-187.
12. Voorhees JL, Tarr AJ, Wohleb ES, et al. (2013): Prolonged restraint stress increases IL-6, reduces IL-10, and causes persistent depressive-like behavior that is reversed by recombinant IL-10. PLoS One. 8: e58488. doi: 10.1371/journal.pone.0058488.
13. Jiang B, Xiong Z, Yang J, et al. (2012): Antidepressant-like effects of ginsenoside Rg1 are due to activation of the BDNF signaling pathway and neurogenesis in the hippocampus. Br J Pharmacol 166: 1872-1887.
14. Bus BA, Molendijk ML, Tendolkar I, et al. (2014): Chronic depression is associated with a pronounced decrease in serum brain-derived neurotrophic factor over time. Mol Psychiatry doi:10. 1038/mp.2014.83.
15. Li Y, Ji YJ, Jiang H, et al. (2009): Effects of unpredictable chronic stress on behavior and brain-derived neurotrophic factor expression in CA3 subfield and dentate gyrus of the hippocampus in different aged rats. Chin Med J (Engl) 122: 1564-1569.
16. Dwivedi Y (2009): Brain-derived neurotrophic factor: role in depression and suicide. Neuropsychiatr Dis Treat 5: 433-449.
17. Hoshaw BA, Malberg JE, Lucki I. (2005): Central administration of IGF-I and BDNF leads to long-lasting antidepressant-like effects. Brain Res 1037: 204-208.
18. Kenis G, Prickaerts J, van Os J, et al. (2011): Depressive symptoms following interferon-α therapy: mediated by immune-induced reductions in brain-derived neurotrophic factor? Int J Neuropsychopharmacol 14: 247-253.
19. Lotrich FE, Albusaysi S, Ferrell RE (2013): Brain-derived neurotrophic factor serum levels and genotype: association with depression during interferon-alpha treatment. Neuropsychopharmacology 38: 985-995.
20. Xie W, Qiu X, Huang X, et al. (2013): Comparison between the pharmacokinetics of meranzin hydrate in a rat model of chronic depression and in controls following the oral administration of Chaihu-Shugan-San. Exp Ther Med 6: 913-918.
21. Wang Z, Zhang Q, Yuan L, et al. (2014): The effects of curcumin on depressive-like behavior in mice after lipopolysaccharide administration. Behav Brain Res 274C: 282-290.
22. Mdzinarishvili A, Sumbria R, Lang D, et al. (2012): Ginkgo extract EGb761 confers neuroprotection by reduction of glutamate release in ischemic brain. J Pharm Pharm Sci 15: 94-102.
23. Chen YJ, Tsai KS, Chiu CY, et al. (2013): EGb761 inhibits inflammatory responses in human chondrocytes and shows chondroprotection in osteoarthritic rat knee. J Orthop Res 31: 1032-1038.
24. Zhang Z, Peng D, Zhu H, et al. (2012): Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent inischemia stroke rats. Brain Res Bull 87: 193-198.
25. Rojas P, Serrano-García N, Medina-Campos ON, et al. (2011): Antidepressant-like effect of a Ginkgo biloba extract (EGb761) in the mouse forced swimming test: role of oxidative stress. Neurochem Int 59: 628-636.
26. O'Connor JC, Lawson MA, André C, et al. (2009): Lipopolysaccharide-induced depressive-like behavior is mediated by indoleamine 2,3-dioxygenase activation in mice. Mol Psychiatry 14: 511-522.
27. Arbabi L, Baharuldin MT, Moklas MA, et al. (2014): Anti-depressant-like effects of omega-3 fatty acids in postpartum model ofdepression in rats. Behav Brain Res 271: 65-71.
28. Lin YL, Wang S (2014): Prenatal lipopolysaccharide exposure increases depression- like behaviors and reduces hippocampal neurogenesis in adult rats. Behav Brain Res 259: 24-34.
29. Satomura E, Baba H, Nakano Y, et al. (2011): Correlations between brain-derived neurotrophic factor and clinical symptoms in medicated patients with major depression. J Affect Disord 135: 332-335.