Tandem prenyltransferases catalyze isoprenoid elongation and complexity generation in biosynthesis of quinolone alkaloids

Journal of the American Chemical Society

Volumn 137, Issue 15, 2015, Pages 4980-4983

  Zou, Yi ^a   Zhan, Zhajun ^a,c   Li, Dehai ^a,d   Tang, Mancheng ^a   Cacho, Ralph A ^a   Watanabe, Kenji ^e   Tang, Yi ^a,b  

^a Department of Chemical and Biomolecular Engineering ^*  (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c ZHEJIANG UNIVERSITY OF TECHNOLOGY   (China)

^d OCEAN UNIVERSITY OF CHINA   (China)

^e UNIVERSITY OF SHIZUOKA   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALKALOIDS; ALKYLATION; BIOSYNTHESIS; CHAINS; METABOLITES; NITROGEN COMPOUNDS;

CHAIN EXTENSION; FLAVIN-DEPENDENT MONOOXYGENASE; FRIEDEL-CRAFTS ALKYLATION; NATURAL PRODUCTS; OXIDATIVE TRANSFORMATIONS; PRENYLTRANSFERASES; QUINOLONE ALKALOIDS; STRUCTURAL COMPLEXITY;

BIOCHEMISTRY;

ALKALOID; DIMETHYLALLYLTRANSFERASE; ISOPRENOID; PRENYLTRANSFERASE G; PRENYLTRANSFERASE I; QUINOLONE; UNCLASSIFIED DRUG; QUINOLONE DERIVATIVE; TERPENE;

ARTICLE; CATALYSIS; CYCLIZATION; DRUG SYNTHESIS; FRIEDEL CRAFTS REACTION; IN VITRO STUDY; NONHUMAN; PRENYLATION; REACTION ANALYSIS; BIOCATALYSIS; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; ENZYMOLOGY; GENETICS; METABOLISM; PENICILLIUM;

ALKALOIDS; BIOCATALYSIS; DIMETHYLALLYLTRANSTRANSFERASE; MOLECULAR STRUCTURE; PENICILLIUM; QUINOLONES; TERPENES;

EID: 84928492275     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/jacs.5b03022     Document Type: Article

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