JSI-124 (Cucurbitacin I) inhibits tumor angiogenesis of human breast cancer through reduction of STAT3 phosphorylation

American Journal of Chinese Medicine

Volumn 43, Issue 2, 2015, Pages 337-347

  Qi, Jia ^a   Xia, Ge ^b   Huang, Cheng Rong ^c   Wang, Jian Xia ^b   Zhang, Jian ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c CHILDREN S HOSPITAL OF FUDAN UNIVERSITY   (China)

Author keywords

Angiogenesis; Breast Cancer; JSI 124; STAT3 Inhibitor

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; CUCURBITACIN I; CYCLIN D1; JANUS KINASE INHIBITOR; NATURAL PRODUCT; PROTEIN BCL XL; STAT3 PROTEIN; UNCLASSIFIED DRUG; VASCULOTROPIN; STAT3 PROTEIN, HUMAN; TRITERPENE; VASCULOTROPIN A;

ANGIOGENESIS; ARTICLE; BREAST CANCER; BREAST CANCER CELL LINE; CELL ADHESION; CELL MIGRATION; CELL PROLIFERATION; CELL VIABILITY; DOSE RESPONSE; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROMOTER REGION; PROTEIN PHOSPHORYLATION; PROTEIN SECRETION; TUMOR MICROENVIRONMENT; AUTOCRINE EFFECT; BREAST TUMOR; CELL MOTION; CELL SURVIVAL; CELL TRANSFORMATION; CHEMICAL PHENOMENA; DRUG EFFECTS; FEMALE; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; NEOVASCULARIZATION, PATHOLOGIC; PATHOLOGY; PHOSPHORYLATION; PHYSIOLOGY; PHYTOTHERAPY; SIGNAL TRANSDUCTION; TUMOR CELL LINE; VASCULARIZATION;

AUTOCRINE COMMUNICATION; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; CELL SURVIVAL; CELL TRANSFORMATION, NEOPLASTIC; DEPRESSION, CHEMICAL; FEMALE; HUMANS; MOLECULAR TARGETED THERAPY; NEOVASCULARIZATION, PATHOLOGIC; PHOSPHORYLATION; PHYTOTHERAPY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TRANSCRIPTION, GENETIC; TRITERPENES; TUMOR MICROENVIRONMENT; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84928410067     PISSN: 0192415X     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0192415X15500226     Document Type: Article

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