Glial cell line-derived neurotrophic factor-mediated enhancement of noradrenergic descending inhibition in the locus coeruleus exerts prolonged analgesia in neuropathic pain

British Journal of Pharmacology

Volumn 172, Issue 10, 2015, Pages 2469-2478

  Kimura, M ^a   Sakai, A ^a   Sakamoto, A ^a   Suzuki, H ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; GLIAL CELL LINE DERIVED NEUROTROPHIC FACTOR; MITOGEN ACTIVATED PROTEIN KINASE; 1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; ALPHA 2 ADRENERGIC RECEPTOR BLOCKING AGENT; ANALGESIC AGENT; ENZYME INHIBITOR; NITRILE; YOHIMBINE;

ADULT; ALLODYNIA; ANALGESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHRONIC CONSTRICTION INJURY; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; HYPERALGESIA; LATENT PERIOD; LOCUS CERULEUS; MALE; NEUROPATHIC PAIN; NEUROTRANSMISSION; NONHUMAN; NORADRENERGIC SYSTEM; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SIGNAL TRANSDUCTION; ADRENERGIC NERVE CELL; ANIMAL; DRUG EFFECTS; INJURIES; INTRASPINAL DRUG ADMINISTRATION; MICROINJECTION; NEURALGIA; PATHOPHYSIOLOGY; PHYSIOLOGY;

ADRENERGIC ALPHA-2 RECEPTOR ANTAGONISTS; ADRENERGIC NEURONS; ANALGESICS; ANIMALS; BUTADIENES; ENZYME INHIBITORS; GLIAL CELL LINE-DERIVED NEUROTROPHIC FACTOR; HYPERALGESIA; INJECTIONS, SPINAL; LOCUS COERULEUS; MALE; MAP KINASE SIGNALING SYSTEM; MICROINJECTIONS; NEURALGIA; NITRILES; RATS; SCIATIC NERVE; YOHIMBINE;

EID: 84928324113     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.13073     Document Type: Article

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