메뉴 건너뛰기




Volumn 329, Issue 2, 2014, Pages 227-233

Cell signaling pathways involved in hematopoietic stem cell specification

Author keywords

Developmental hematopoiesis; Hematopoietic stem cells; Hemogenic endothelium; HSCs; Sclerotome; Signaling; Somites

Indexed keywords

BONE MORPHOGENETIC PROTEIN; NOTCH RECEPTOR; SONIC HEDGEHOG PROTEIN; VASCULOTROPIN; WNT PROTEIN;

EID: 84928273522     PISSN: 00144827     EISSN: 10902422     Source Type: Journal    
DOI: 10.1016/j.yexcr.2014.10.011     Document Type: Review
Times cited : (26)

References (64)
  • 1
    • 84902133026 scopus 로고    scopus 로고
    • Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells
    • Sturgeon C.M., et al. Wnt signaling controls the specification of definitive and primitive hematopoiesis from human pluripotent stem cells. Nat. Biotechnol. 2014, 32(6):554-561.
    • (2014) Nat. Biotechnol. , vol.32 , Issue.6 , pp. 554-561
    • Sturgeon, C.M.1
  • 2
    • 70349202175 scopus 로고    scopus 로고
    • Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell-derived lin-CD34+CD43+CD45+ progenitors
    • Choi K.D., Vodyanik M.A., Slukvin I.I. Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell-derived lin-CD34+CD43+CD45+ progenitors. J. Clin. Invest. 2009, 119(9):2818-2829.
    • (2009) J. Clin. Invest. , vol.119 , Issue.9 , pp. 2818-2829
    • Choi, K.D.1    Vodyanik, M.A.2    Slukvin, I.I.3
  • 3
    • 84871698997 scopus 로고    scopus 로고
    • T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures
    • Kennedy M., et al. T lymphocyte potential marks the emergence of definitive hematopoietic progenitors in human pluripotent stem cell differentiation cultures. Cell. Rep. 2012, 2(6):1722-1735.
    • (2012) Cell. Rep. , vol.2 , Issue.6 , pp. 1722-1735
    • Kennedy, M.1
  • 4
    • 39349106325 scopus 로고    scopus 로고
    • Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development
    • Murry C.E., Keller G. Differentiation of embryonic stem cells to clinically relevant populations: lessons from embryonic development. Cell 2008, 132(4):661-680.
    • (2008) Cell , vol.132 , Issue.4 , pp. 661-680
    • Murry, C.E.1    Keller, G.2
  • 5
    • 77949895151 scopus 로고    scopus 로고
    • Haematopoietic stem cells derive directly from aortic endothelium during development
    • Bertrand J.Y., et al. Haematopoietic stem cells derive directly from aortic endothelium during development. Nature 2010, 464(7285):108-111.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 108-111
    • Bertrand, J.Y.1
  • 6
    • 77949911441 scopus 로고    scopus 로고
    • In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium
    • Boisset J.C., et al. In vivo imaging of haematopoietic cells emerging from the mouse aortic endothelium. Nature 2010, 464(7285):116-120.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 116-120
    • Boisset, J.C.1
  • 7
    • 77949903295 scopus 로고    scopus 로고
    • Blood stem cells emerge from aortic endothelium by a novel type of cell transition
    • Kissa K., Herbomel P. Blood stem cells emerge from aortic endothelium by a novel type of cell transition. Nature 2010, 464(7285):112-115.
    • (2010) Nature , vol.464 , Issue.7285 , pp. 112-115
    • Kissa, K.1    Herbomel, P.2
  • 8
    • 0034214284 scopus 로고    scopus 로고
    • Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo
    • de Bruijn M.F., et al. Definitive hematopoietic stem cells first develop within the major arterial regions of the mouse embryo. EMBO J. 2000, 19(11):2465-2474.
    • (2000) EMBO J. , vol.19 , Issue.11 , pp. 2465-2474
    • de Bruijn, M.F.1
  • 9
    • 56549101520 scopus 로고    scopus 로고
    • Fate tracing reveals the endothelial origin of hematopoietic stem cells
    • Zovein A.C., et al. Fate tracing reveals the endothelial origin of hematopoietic stem cells. Cell Stem Cell 2008, 3(6):625-636.
    • (2008) Cell Stem Cell , vol.3 , Issue.6 , pp. 625-636
    • Zovein, A.C.1
  • 10
    • 0033405452 scopus 로고    scopus 로고
    • Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse
    • Palis J., et al. Development of erythroid and myeloid progenitors in the yolk sac and embryo proper of the mouse. Development 1999, 126(22):5073-5084.
    • (1999) Development , vol.126 , Issue.22 , pp. 5073-5084
    • Palis, J.1
  • 11
    • 33846907357 scopus 로고    scopus 로고
    • The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis
    • Tober J., et al. The megakaryocyte lineage originates from hemangioblast precursors and is an integral component both of primitive and of definitive hematopoiesis. Blood 2007, 109(4):1433-1441.
    • (2007) Blood , vol.109 , Issue.4 , pp. 1433-1441
    • Tober, J.1
  • 12
    • 38349043771 scopus 로고    scopus 로고
    • Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo
    • Bertrand J.Y., et al. Definitive hematopoiesis initiates through a committed erythromyeloid progenitor in the zebrafish embryo. Development 2007, 134(23):4147-4156.
    • (2007) Development , vol.134 , Issue.23 , pp. 4147-4156
    • Bertrand, J.Y.1
  • 13
    • 82755185961 scopus 로고    scopus 로고
    • Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells
    • Chen M.J., et al. Erythroid/myeloid progenitors and hematopoietic stem cells originate from distinct populations of endothelial cells. Cell Stem Cell 2011, 9(6):541-552.
    • (2011) Cell Stem Cell , vol.9 , Issue.6 , pp. 541-552
    • Chen, M.J.1
  • 14
    • 69249158143 scopus 로고    scopus 로고
    • Zebrafish blood stem cells
    • Chen A.T., Zon L.I. Zebrafish blood stem cells. J. Cell. Biochem. 2009, 108(1):35-42.
    • (2009) J. Cell. Biochem. , vol.108 , Issue.1 , pp. 35-42
    • Chen, A.T.1    Zon, L.I.2
  • 15
    • 84905185118 scopus 로고    scopus 로고
    • Developmental hematopoiesis: ontogeny, genetic programming and conservation
    • Ciau-Uitz A., et al. Developmental hematopoiesis: ontogeny, genetic programming and conservation. Exp. Hematol. 2014, 42(8):669-683.
    • (2014) Exp. Hematol. , vol.42 , Issue.8 , pp. 669-683
    • Ciau-Uitz, A.1
  • 16
    • 77950991183 scopus 로고    scopus 로고
    • Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo
    • Bertrand J.Y., et al. Notch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo. Blood 2010, 115(14):2777-2783.
    • (2010) Blood , vol.115 , Issue.14 , pp. 2777-2783
    • Bertrand, J.Y.1
  • 17
    • 0030595341 scopus 로고    scopus 로고
    • Definitive hematopoiesis is autonomously initiated by the AGM region
    • Medvinsky A., Dzierzak E. Definitive hematopoiesis is autonomously initiated by the AGM region. Cell 1996, 86(6):897-906.
    • (1996) Cell , vol.86 , Issue.6 , pp. 897-906
    • Medvinsky, A.1    Dzierzak, E.2
  • 18
    • 0028467947 scopus 로고
    • Development of hematopoietic stem cell activity in the mouse embryo
    • Muller A.M., et al. Development of hematopoietic stem cell activity in the mouse embryo. Immunity 1994, 1(4):291-301.
    • (1994) Immunity , vol.1 , Issue.4 , pp. 291-301
    • Muller, A.M.1
  • 19
    • 0030753347 scopus 로고    scopus 로고
    • Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo
    • Turpen J.B., et al. Bipotential primitive-definitive hematopoietic progenitors in the vertebrate embryo. Immunity 1997, 7(3):325-334.
    • (1997) Immunity , vol.7 , Issue.3 , pp. 325-334
    • Turpen, J.B.1
  • 20
    • 36448936383 scopus 로고    scopus 로고
    • TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility
    • Schmierer B., Hill C.S. TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat. Rev. Mol. Cell. Biol. 2007, 8(12):970-982.
    • (2007) Nat. Rev. Mol. Cell. Biol. , vol.8 , Issue.12 , pp. 970-982
    • Schmierer, B.1    Hill, C.S.2
  • 21
    • 6244256053 scopus 로고
    • Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis
    • Mishina Y., et al. Bmpr encodes a type I bone morphogenetic protein receptor that is essential for gastrulation during mouse embryogenesis. Genes Dev. 1995, 9(24):3027-3037.
    • (1995) Genes Dev. , vol.9 , Issue.24 , pp. 3027-3037
    • Mishina, Y.1
  • 22
    • 0029149656 scopus 로고
    • Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse
    • Winnier G., et al. Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse. Genes Dev. 1995, 9(17):2105-2116.
    • (1995) Genes Dev. , vol.9 , Issue.17 , pp. 2105-2116
    • Winnier, G.1
  • 23
    • 66949174086 scopus 로고    scopus 로고
    • Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta
    • Wilkinson R.N., et al. Hedgehog and Bmp polarize hematopoietic stem cell emergence in the zebrafish dorsal aorta. Dev. Cell 2009, 16(6):909-916.
    • (2009) Dev. Cell , vol.16 , Issue.6 , pp. 909-916
    • Wilkinson, R.N.1
  • 24
    • 38049138738 scopus 로고    scopus 로고
    • Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells
    • Durand C., et al. Embryonic stromal clones reveal developmental regulators of definitive hematopoietic stem cells. Proc. Natl. Acad. Sci. USA 2007, 104(52):20838-20843.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , Issue.52 , pp. 20838-20843
    • Durand, C.1
  • 25
    • 53249101499 scopus 로고    scopus 로고
    • An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney
    • Blank U., et al. An in vivo reporter of BMP signaling in organogenesis reveals targets in the developing kidney. BMC Dev. Biol. 2008, 8:86.
    • (2008) BMC Dev. Biol. , vol.8 , pp. 86
    • Blank, U.1
  • 26
    • 84858286273 scopus 로고    scopus 로고
    • Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades
    • Moya I.M., et al. Stalk cell phenotype depends on integration of Notch and Smad1/5 signaling cascades. Dev. Cell 2012, 22(3):501-514.
    • (2012) Dev. Cell , vol.22 , Issue.3 , pp. 501-514
    • Moya, I.M.1
  • 27
    • 84896323263 scopus 로고    scopus 로고
    • Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence
    • Zhang C., et al. Inhibition of endothelial ERK signalling by Smad1/5 is essential for haematopoietic stem cell emergence. Nat. Commun. 2014, 5:3431.
    • (2014) Nat. Commun. , vol.5 , pp. 3431
    • Zhang, C.1
  • 28
    • 77954704813 scopus 로고    scopus 로고
    • Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture
    • Singbrant S., et al. Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture. Blood 2010, 115(23):4689-4698.
    • (2010) Blood , vol.115 , Issue.23 , pp. 4689-4698
    • Singbrant, S.1
  • 29
    • 0025815911 scopus 로고
    • Role of the Drosophila patched gene in positional signalling
    • Ingham P.W., Taylor A.M., Nakano Y. Role of the Drosophila patched gene in positional signalling. Nature 1991, 353(6340):184-187.
    • (1991) Nature , vol.353 , Issue.6340 , pp. 184-187
    • Ingham, P.W.1    Taylor, A.M.2    Nakano, Y.3
  • 30
    • 0029896212 scopus 로고    scopus 로고
    • Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus
    • Dominguez M., et al. Sending and receiving the hedgehog signal: control by the Drosophila Gli protein Cubitus interruptus. Science 1996, 272(5268):1621-1625.
    • (1996) Science , vol.272 , Issue.5268 , pp. 1621-1625
    • Dominguez, M.1
  • 31
    • 69049109901 scopus 로고    scopus 로고
    • Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development
    • Peeters M., et al. Ventral embryonic tissues and Hedgehog proteins induce early AGM hematopoietic stem cell development. Development 2009, 136(15):2613-2621.
    • (2009) Development , vol.136 , Issue.15 , pp. 2613-2621
    • Peeters, M.1
  • 32
    • 14644394305 scopus 로고    scopus 로고
    • Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos
    • Gering M., Patient R. Hedgehog signaling is required for adult blood stem cell formation in zebrafish embryos. Dev. Cell 2005, 8(3):389-400.
    • (2005) Dev. Cell , vol.8 , Issue.3 , pp. 389-400
    • Gering, M.1    Patient, R.2
  • 33
    • 0036070186 scopus 로고    scopus 로고
    • Sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation
    • Lawson N.D., Vogel A.M., Weinstein B.M. sonic hedgehog and vascular endothelial growth factor act upstream of the Notch pathway during arterial endothelial differentiation. Dev. Cell 2002, 3(1):127-136.
    • (2002) Dev. Cell , vol.3 , Issue.1 , pp. 127-136
    • Lawson, N.D.1    Vogel, A.M.2    Weinstein, B.M.3
  • 34
    • 0026395163 scopus 로고
    • The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA
    • Houck K.A., et al. The vascular endothelial growth factor family: identification of a fourth molecular species and characterization of alternative splicing of RNA. Mol. Endocrinol. 1991, 5(12):1806-1814.
    • (1991) Mol. Endocrinol. , vol.5 , Issue.12 , pp. 1806-1814
    • Houck, K.A.1
  • 35
    • 0025999033 scopus 로고
    • The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing
    • Tischer E., et al. The human gene for vascular endothelial growth factor. Multiple protein forms are encoded through alternative exon splicing. J. Biol. Chem. 1991, 266(18):11947-11954.
    • (1991) J. Biol. Chem. , vol.266 , Issue.18 , pp. 11947-11954
    • Tischer, E.1
  • 37
    • 0343920277 scopus 로고    scopus 로고
    • Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele
    • Carmeliet P., et al. Abnormal blood vessel development and lethality in embryos lacking a single VEGF allele. Nature 1996, 380(6573):435-439.
    • (1996) Nature , vol.380 , Issue.6573 , pp. 435-439
    • Carmeliet, P.1
  • 38
    • 0029006696 scopus 로고
    • Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice
    • Shalaby F., et al. Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice. Nature 1995, 376(6535):62-66.
    • (1995) Nature , vol.376 , Issue.6535 , pp. 62-66
    • Shalaby, F.1
  • 39
    • 84873094555 scopus 로고    scopus 로고
    • Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification
    • Leung A., et al. Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification. Dev. Cell 2013, 24(2):144-158.
    • (2013) Dev. Cell , vol.24 , Issue.2 , pp. 144-158
    • Leung, A.1
  • 40
    • 77951903935 scopus 로고    scopus 로고
    • Tel1/ETV6 specifies blood stem cells through the agency of VEGF signaling
    • Ciau-Uitz A., et al. Tel1/ETV6 specifies blood stem cells through the agency of VEGF signaling. Dev. Cell 2010, 18(4):569-578.
    • (2010) Dev. Cell , vol.18 , Issue.4 , pp. 569-578
    • Ciau-Uitz, A.1
  • 41
    • 1642382833 scopus 로고    scopus 로고
    • Notch signaling: control of cell communication and cell fate
    • Lai E.C. Notch signaling: control of cell communication and cell fate. Development 2004, 131(5):965-973.
    • (2004) Development , vol.131 , Issue.5 , pp. 965-973
    • Lai, E.C.1
  • 42
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: unfolding the activation mechanism
    • Kopan R., Ilagan M.X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell 2009, 137(2):216-233.
    • (2009) Cell , vol.137 , Issue.2 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 43
    • 25844493155 scopus 로고    scopus 로고
    • Hematopoietic stem cell fate is established by the Notch-Runx pathway
    • Burns C.E., et al. Hematopoietic stem cell fate is established by the Notch-Runx pathway. Genes Dev. 2005, 19(19):2331-2342.
    • (2005) Genes Dev. , vol.19 , Issue.19 , pp. 2331-2342
    • Burns, C.E.1
  • 44
    • 16844366556 scopus 로고    scopus 로고
    • RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
    • Robert-Moreno A., et al. RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells. Development 2005, 132(5):1117-1126.
    • (2005) Development , vol.132 , Issue.5 , pp. 1117-1126
    • Robert-Moreno, A.1
  • 45
    • 47949124470 scopus 로고    scopus 로고
    • Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches
    • Yoon M.J., et al. Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches. Mol. Cell. Biol. 2008, 28(15):4794-4804.
    • (2008) Mol. Cell. Biol. , vol.28 , Issue.15 , pp. 4794-4804
    • Yoon, M.J.1
  • 46
    • 8644225027 scopus 로고    scopus 로고
    • A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development
    • Hadland B.K., et al. A requirement for Notch1 distinguishes 2 phases of definitive hematopoiesis during development. Blood 2004, 104(10):3097-3105.
    • (2004) Blood , vol.104 , Issue.10 , pp. 3097-3105
    • Hadland, B.K.1
  • 47
    • 0038404519 scopus 로고    scopus 로고
    • Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells
    • Kumano K., et al. Notch1 but not Notch2 is essential for generating hematopoietic stem cells from endothelial cells. Immunity 2003, 18(5):699-711.
    • (2003) Immunity , vol.18 , Issue.5 , pp. 699-711
    • Kumano, K.1
  • 48
    • 0034212710 scopus 로고    scopus 로고
    • Notch signaling is essential for vascular morphogenesis in mice
    • Krebs L.T., et al. Notch signaling is essential for vascular morphogenesis in mice. Genes Dev. 2000, 14(11):1343-1352.
    • (2000) Genes Dev. , vol.14 , Issue.11 , pp. 1343-1352
    • Krebs, L.T.1
  • 49
    • 46949110648 scopus 로고    scopus 로고
    • Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1
    • Robert-Moreno A., et al. Impaired embryonic haematopoiesis yet normal arterial development in the absence of the Notch ligand Jagged1. EMBO J. 2008, 27(13):1886-1895.
    • (2008) EMBO J. , vol.27 , Issue.13 , pp. 1886-1895
    • Robert-Moreno, A.1
  • 50
    • 84911474028 scopus 로고    scopus 로고
    • Discrete Notch signaling requirements in the specification of hematopoietic stem cells
    • Kim A.D., et al. Discrete Notch signaling requirements in the specification of hematopoietic stem cells. EMBO J. 2014.
    • (2014) EMBO J.
    • Kim, A.D.1
  • 51
    • 84911474028 scopus 로고    scopus 로고
    • Discrete Notch signaling requirements in the specification of hematopoietic stem cells
    • Kim A.D., et al. Discrete Notch signaling requirements in the specification of hematopoietic stem cells. EMBO J 2014, 33(20):2363-2373.
    • (2014) EMBO J , vol.33 , Issue.20 , pp. 2363-2373
    • Kim, A.D.1
  • 52
    • 0029994517 scopus 로고    scopus 로고
    • A new member of the frizzled family from Drosophila functions as a Wingless receptor
    • Bhanot P., et al. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 1996, 382(6588):225-230.
    • (1996) Nature , vol.382 , Issue.6588 , pp. 225-230
    • Bhanot, P.1
  • 53
    • 0030265570 scopus 로고    scopus 로고
    • A frizzled homolog functions in a vertebrate Wnt signaling pathway
    • Yang-Snyder J., et al. A frizzled homolog functions in a vertebrate Wnt signaling pathway. Curr. Biol. 1996, 6(10):1302-1306.
    • (1996) Curr. Biol. , vol.6 , Issue.10 , pp. 1302-1306
    • Yang-Snyder, J.1
  • 54
    • 0030978351 scopus 로고    scopus 로고
    • Beta-catenin is a target for the ubiquitin-proteasome pathway
    • Aberle H., et al. Beta-catenin is a target for the ubiquitin-proteasome pathway. EMBO J. 1997, 16(13):3797-3804.
    • (1997) EMBO J. , vol.16 , Issue.13 , pp. 3797-3804
    • Aberle, H.1
  • 55
    • 0037022275 scopus 로고    scopus 로고
    • Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex
    • Gao Z.H., et al. Casein kinase I phosphorylates and destabilizes the beta-catenin degradation complex. Proc. Natl. Acad. Sci. USA 2002, 99(3):1182-1187.
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , Issue.3 , pp. 1182-1187
    • Gao, Z.H.1
  • 56
    • 67649470380 scopus 로고    scopus 로고
    • Proximal events in Wnt signal transduction
    • Angers S., Moon R.T. Proximal events in Wnt signal transduction. Nat. Rev. Mol. Cell. Biol. 2009, 10(7):468-477.
    • (2009) Nat. Rev. Mol. Cell. Biol. , vol.10 , Issue.7 , pp. 468-477
    • Angers, S.1    Moon, R.T.2
  • 57
    • 84866443757 scopus 로고    scopus 로고
    • Hematopoietic stem cell development requires transient Wnt/beta-catenin activity
    • Ruiz-Herguido C., et al. Hematopoietic stem cell development requires transient Wnt/beta-catenin activity. J. Exp. Med. 2012, 209(8):1457-1468.
    • (2012) J. Exp. Med. , vol.209 , Issue.8 , pp. 1457-1468
    • Ruiz-Herguido, C.1
  • 58
    • 79958290042 scopus 로고    scopus 로고
    • A somitic Wnt16/Notch pathway specifies haematopoietic stem cells
    • Clements W.K., et al. A somitic Wnt16/Notch pathway specifies haematopoietic stem cells. Nature 2011, 474(7350):220-224.
    • (2011) Nature , vol.474 , Issue.7350 , pp. 220-224
    • Clements, W.K.1
  • 59
    • 62149148156 scopus 로고    scopus 로고
    • Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration
    • Goessling W., et al. Genetic interaction of PGE2 and Wnt signaling regulates developmental specification of stem cells and regeneration. Cell 2009, 136(6):1136-1147.
    • (2009) Cell , vol.136 , Issue.6 , pp. 1136-1147
    • Goessling, W.1
  • 60
    • 84873546335 scopus 로고    scopus 로고
    • Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition
    • Rafii S., et al. Human ESC-derived hemogenic endothelial cells undergo distinct waves of endothelial to hematopoietic transition. Blood 2013, 121(5):770-780.
    • (2013) Blood , vol.121 , Issue.5 , pp. 770-780
    • Rafii, S.1
  • 61
    • 84899527626 scopus 로고    scopus 로고
    • Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors
    • Riddell J., et al. Reprogramming committed murine blood cells to induced hematopoietic stem cells with defined factors. Cell 2014, 157(3):549-564.
    • (2014) Cell , vol.157 , Issue.3 , pp. 549-564
    • Riddell, J.1
  • 62
    • 78649471039 scopus 로고    scopus 로고
    • Direct conversion of human fibroblasts to multilineage blood progenitors
    • Szabo E., et al. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature 2010, 468(7323):521-526.
    • (2010) Nature , vol.468 , Issue.7323 , pp. 521-526
    • Szabo, E.1
  • 63
    • 84881149632 scopus 로고    scopus 로고
    • Induction of a hemogenic program in mouse fibroblasts
    • Pereira C.F., et al. Induction of a hemogenic program in mouse fibroblasts. Cell Stem Cell 2013, 13(2):205-218.
    • (2013) Cell Stem Cell , vol.13 , Issue.2 , pp. 205-218
    • Pereira, C.F.1
  • 64
    • 84904439259 scopus 로고    scopus 로고
    • Reprogramming human endothelial cells to haematopoietic cells requires vascular induction
    • Sandler V.M., et al. Reprogramming human endothelial cells to haematopoietic cells requires vascular induction. Nature 2014, 511(7509):312-318.
    • (2014) Nature , vol.511 , Issue.7509 , pp. 312-318
    • Sandler, V.M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.