Astrocyte-targeted production of IL-10 induces changes in microglial reactivity and reduces motor neuron death after facial nerve axotomy

GLIA

Volumn 63, Issue 7, 2015, Pages 1166-1184

  Villacampa, Nàdia ^a   Almolda, Beatriz ^a   Vilella, Antonietta ^b   Campbell, Iain L ^c   González, Berta ^a   Castellano, Bernardo ^a  

^a INSTITUT DE NEUROCIÈNCIES   (Spain)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Arginase 1; CD150; CD16 32; CD18; CD39; Cytokines; IL 10R; Lymphocytes; MHC II; Microglia; Nerve injury; Neurodegeneration; Neuronal survival; Transgenic animal; Ym 1

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; GLIAL FIBRILLARY ASTROCYTIC PROTEIN, MOUSE; IL10 PROTEIN, MOUSE; INTERLEUKIN 10; MESSENGER RNA; NERVE PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL ACTIVATION; CELL DENSITY; CELL SURVIVAL; CONTROLLED STUDY; CORRELATIONAL STUDY; CYTOKINE PRODUCTION; FACIAL NERVE INJURY; FEMALE; GENE; GENE EXPRESSION; INTERLEUKIN 10 GENE; LEUKOCYTE; LYMPHOCYTE; LYMPHOCYTIC INFILTRATION; MALE; MICROGLIA; MOTONEURON; MOUSE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NERVE FIBER TRANSECTION; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROMOTER REGION; TRANSCRIPTION REGULATION; TRANSGENIC MOUSE; ANIMAL; CELL DEATH; DISEASE MODEL; FACIAL NERVE; GENETICS; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; ASTROCYTES; AXOTOMY; CELL DEATH; DISEASE MODELS, ANIMAL; FACIAL NERVE; FACIAL NERVE INJURIES; FEMALE; INTERLEUKIN-10; LYMPHOCYTES; MALE; MICE, TRANSGENIC; MICROGLIA; MOTOR NEURONS; NERVE TISSUE PROTEINS; RNA, MESSENGER;

EID: 84928206833     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.22807     Document Type: Article

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