Triclosan resistance in a bacterial fish pathogen, Aeromonas salmonicida subsp. salmonicida, is mediated by an enoyl reductase, FabV

Journal of Microbiology and Biotechnology

Volumn 25, Issue 4, 2015, Pages 511-520

  Khan, Raees ^a   Lee, Myung Hwan ^a   Joo, Haejin ^a   Jung, Yong Hoon ^a   Ahmad, Shabir ^a   Choi, Jinhee ^a   Lee, Seon Woo ^a  

^a Dong A University   (South Korea)

Author keywords

Aeromonas salmonicida; Enoyl reductase; FabV; Triclosan resistance

Indexed keywords

BACTERIAL DNA; OXIDOREDUCTASE; PROTEIN FABI; PROTEIN FABV; TRICLOSAN; UNCLASSIFIED DRUG; ENOYL ACYL CARRIER PROTEIN REDUCTASE (NADPH); TOPICAL ANTIINFECTIVE AGENT;

AEROMONAS SALMONICIDA; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL GENOME; BACTERIAL STRAIN; CONTROLLED STUDY; DNA SEQUENCE; ENZYME ACTIVE SITE; ESCHERICHIA COLI; FABV GENE; FABVAS GENE; FOSMID; GENE EXPRESSION; GENE IDENTIFICATION; HETEROLOGOUS EXPRESSION; IN VIVO STUDY; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; ORTHOLOGY; PARALOGY; SEQUENCE HOMOLOGY; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; FISH; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; PLASMID; PROTEIN DOMAIN; SEQUENCE ALIGNMENT;

AEROMONAS SALMONICIDA; AEROMONAS SALMONICIDA SUBSP. SALMONICIDA; BACTERIA (MICROORGANISMS); NEGIBACTERIA;

AEROMONAS SALMONICIDA; AMINO ACID SEQUENCE; ANIMALS; ANTI-INFECTIVE AGENTS, LOCAL; CLONING, MOLECULAR; DRUG RESISTANCE, BACTERIAL; ENOYL-(ACYL-CARRIER PROTEIN) REDUCTASE (NADPH, B-SPECIFIC); FISHES; GENE EXPRESSION REGULATION, BACTERIAL; MICROBIAL SENSITIVITY TESTS; MOLECULAR SEQUENCE DATA; PLASMIDS; PROTEIN INTERACTION DOMAINS AND MOTIFS; SEQUENCE ALIGNMENT; TRANSCRIPTION, GENETIC; TRICLOSAN;

EID: 84928158808     PISSN: 10177825     EISSN: 17388872     Source Type: Journal    
DOI: 10.4014/jmb.1407.07021     Document Type: Article

References (49)

1. Amos GC, Zhang L, Hawkey PM, Gaze WH, Wellington EM. 2014. Functional metagenomic analysis reveals rivers are a reservoir for diverse antibiotic resistance genes. Vet. Microbiol. http://dx. doi. org/10. 1016/j. vetmic. 2014. 02. 017.
2. Bailey AM, Paulsen IT, Piddock LJ. 2008. RamA confers multidrug resistance in Salmonella enterica via increased expression of acrB, which is inhibited by chlorpromazine. Antimicrob. Agents Chemother. 52: 3604-3611.
3. Bergler H, Hogenauer G, Turnowsky F. 1992. Sequences of the envM gene and of two mutated alleles in Escherichia coli. J. Gen. Microbiol. 138: 2093-2100.
4. Bergler H, Wallner P, Ebeling A, Leitinger B, Fuchsbichler S, Aschauer H, et al. 1994. Protein EnvM is the NADHdependent enoyl-ACP reductase (FabI) of Escherichia coli. J. Biol. Chem. 269: 5493-5496.
5. Byrne-Bailey KG, G aze W H, Z hang L, Kay P, B oxall A, Hawkey PM, Wellington EM. 2011. Integron prevalence and diversity in manured soil. Appl. Environ. Microbiol. 77: 684-687.
6. Chen Y, Pi B, Zhou H, Yu Y, Li L. 2009. Triclosan resistance in clinical isolates of Acinetobacter baumannii. J. Med. Microbiol. 58: 1086-1091.
7. Chuanchuen R, Beinlich K, Hoang TT, Becher A, Karkhoff-Schweizer RR, Schweizer HP. 2001. Cross resistance between triclosan and antibiotics in Pseudomonas aeruginosa is mediated by multidrug efflux pumps: exposure of a susceptible mutant strain to triclosan selects nfxB mutants overexpressing MexCD-OprJ. Antimicrob. Agents Chemother. 45: 428-432.
8. Daly JG, Kew AK, Moore AR, Olivier G. 1996. The cell surface of Aeromonas salmonicida determines in vitro survival in cultured brook trout (Salvelinus fontinalis) peritoneal macrophages. Microb. Pathog. 21: 447-461.
9. Dias C, Mota V, Martinez-Murcia A, Saavedra MJ. 2012. Antimicrobial resistance patterns of Aeromonas spp. isolated from ornamental fish. J. Aquacult. Res. Dev. 3: 131.
10. Fair PA, Lee HB, Adams J, Darling C, Pacepavicius G, Alaee M, et al. 2009. Occurrence of triclosan in plasma of wild atlantic bottlenose dolphins (Tursiops truncates) and in their environment. Environ. Pollut. 157: 2248-2254.
11. Figueras MJ. 2005. Clinical relevance of Aeromonas sM503. Rev. Med. Microbiol. 16: 145-153.
12. Fraise AP. 2002. Biocide abuse and antimicrobial resistance - a cause for concern. J. Antimicrob. Chemother. 49: 11-12.
13. Haldar S, Chatterjee S, Sugimoto N, Das S, Chowdhury N, Hinenoya A, et al. 2011. Identification of Vibrio campbellii isolated from diseased farm-shrimps from south India and establishment of its pathogenic potential in an Artemia model. Microbiology 157: 179-188.
14. Heath RJ, Rubins JR, Holland DR, Zhang E, Snow ME, Rock CO. 1999. Mechanism of triclosan inhibition of bacterial fatty acid synthesis. J. Biol. Chem. 274: 11110-11114.
15. HeathRJ, Rock CO. 2000. A triclosan-resistant bacterial enzyme. Nature 406: 145-146.
16. Heath RJ, Su N, Murphy CK, Rock CO. 2000. The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis. J. Biol. Chem. 275: 40128-40133.
17. Hirschbeck MW, Kuper J, Lu H, Liu N, Neckles C, Shah S, et al. 2012. Structure of the Yersinia pestis FabV enoyl-ACP reductase and its interaction with two novel 2-pyridone inhibitors. Structure 20: 89-100.
18. Jackowski S, Murphy CM, Cronan JE, Rock CO. 1987. Acetoacetyl-acyl carrier protein synthase: a target for the antibiotic thiolactomycin. J. Biol. Chem. 264: 7624-7629.
19. Keen NT, Tamaki S, Kobayashi D, Trollinger D. 1988. Improved broad-host-range plasmids for DNA cloning in gram-negative bacteria. Gene 70: 191-197.
20. Lei Z, Hongkai B, Jincheng M, Zhe H, Wenbin Z, John EC, Haihong W. 2013. The two functional enoyl-acyl carrier protein reductases of Enterococcus faecalis do not mediate triclosan resistance. mBio 4: doi: 10. 1128/mBio. 00613-13.
21. Lu H, Tonge PJ. 2010. Mechanism and inhibition of the FabV enoyl ACP reductase from Burkholderia mallei. Biochemistry 49: 1281-1289.
22. Marrakchi H, Dewolf WE, Quinn C, West J, Polizzi BJ, So CY, et al. 2003. Characterization of Streptococcus pneumonia enoyl-(acyl-carrier protein) reductase (FabK). Biochem. J. 370: 1055-1062.
23. Marti E, Variatza E, Balcazar JL. 2014. The role of aquatic ecosystems as reservoirs of antibiotic resistance. Trends Microbiol. 22: 36-41.
24. Massengo-Tiasse RP, Cronan JE. 2009. Diversity in enoyl-acyl carrier protein reductases. Cell. Mol. Life Sci. 66: 1507-1517.
25. Massengo-Tiasse RP, Cronan JE. 2008. Vibrio cholera FabV defines a new class of enoyl-acyl carrier protein reductase. J. Biol. Chem. 283: 1308-1316.
26. McMurry LM, McDermott PF, Levy SB. 1999. Genetic evidence that InhA of Mycobacterium smegmatisis is a t arg et for triclosan. Antimicrob. Agents Chemother. 43: 711-713.
27. McMurry LM, Oething er M, Levy SB. 1998. Overexpression of marA, soxS, or acrAB produces resistance to triclosan in laboratory and clinical strains of Escherichia coli. FEMS Microbiol. Lett. 166: 305-309.
28. McMurry LM, Oethinger M, Levy SB. 1998. Triclosan targets lipid synthesis. Nature 394: 531-532.
29. Ochman H, Lawrence JG, Groisman EA. 2000. Lateral gene transfer and the nature of bacterial innovation. Nature 405: 299-304.
30. Okumura T, Nishikawa Y. 1996. Gas chromatography-mass spectrometry determination of triclosans in water, sediment and fish samples via methylation with diazomethane. Anal. Chim. Acta 325: 175-184.
31. Persson B, Hedlund J, Jornvall H. 2008. Medium and shortchain dehydrogenase/reductase gene and protein families. Cell. Mol. Life Sci. 65: 3895-3906.
32. Reith ME, Singh RK, Curtis B, Boyd JM, Bouevitch A, Kimball J, et al. 2008. The genome of Aeromonas salmonicida subsp. salmonicida A449: insights into the evolution of a fish pathogen. BMC Genomics 9: 427.
33. Rhodes G, Huys G, Swings J, Mcgann P, Hiney M, Smith P, Pickup RW. 2000. Distribution of oxytetracycline resistance plasmids between aeromonads in hospital and aquaculture environments: implication of Tn1721 in dissemination of the tetracycline resistance determinant tetA. Appl. Environ. Microbiol. 66: 3883-3890.
34. Rizzo L, Manaia C, Merlin C, Schwartz T, Dagot C, Ploy MC, et al. 2013. Urban wastewater treatment plants as hotspots for antibiotic resistant bacteria and genes spread into the environment: a review. Sci. Tot. Environ. 447: 345-360.
35. Russell AD. 2004. Whither triclosan? J. Antimicrob. Chemother. 53: 693-695.
36. Saleh S, Haddadin RN, Baillie S, Collier PJ. 2010. Triclosan-an update. Lett. Appl. Microbiol. 52: 87-95.
37. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular Cloning: A Laboratory Manual, 3rd Ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
38. Sorum H, Abee-Lund TM, Solberg A, Wold A. 2003. Integron-containing IncU R plasmids pRAS1 and pAr-32 from the fish pathogen Aeromonas salmonicida. Antimicrob. Agents Chemother. 47: 1285-1290.
39. Sudheesh PS, Al-Ghabshi A, Al-Mazrooei N, Al-Habsi S. 2012. Comparative pathogenomics of bacteria causing infectious diseases in fish. Int. J. Evol. Biol. 2012. doi: 10. 1155/2012/457264.
40. Tkachenko O, Shepard J, Aris VM, Joy A, Bello A, Londono I, et al. 2007. A triclosan-ciprofloxacin cross-resistant mutant strain of Staphylococcus aureus displays an alteration in the expression of several cell membrane structural and functional genes. Res. Microbiol. 158: 651-658.
41. Walsh F. 2013. Investigating antibiotic resistance in nonclinical environments. Front. Microbiol. 4: 1-5.
42. Wellington EM, Boxall AB, Cross P, Feil EJ, Gaze WH, Hawkey PM, et al. 2013. The role of the natural environment in the emergence of antibiotic resistance in gram-negative bacteria. Lancet Infect. Dis. 13: 155-165.
43. Wiklund T, Dalsgaard I. 1998. Occurrence and significance of atypical Aeromonas salmonicida in non-salmonid and salmonid fish species: a review. Dis. Aquat. Org. 32: 49-69.
44. Xie Z, Ebinghaus R, Floser G, Caba A, Ruck W. 2008. Occurrence and distribution of triclosan in the German Bight (North Sea). Environ. Pollut. 156: 1190-1195.
45. Yanisch-Perron C, Vieira J, Messing J. 1985. Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectors. Gene 33: 103-119.
46. Yazdankhah SP, Scheie AA, Hoiby EA, Lunestad BT, Heir E, Fotland TO, et al. 2006. Triclosan and antimicrobial resistance in bacteria: an overview. Microb. Drug Resist. 12: 83-90.
47. Yu BJ, Kim JA, Pan JG. 2010. Signature gene expression profile of triclosan-resistant Escherichia coli. J. Antimicrob. Chemother. 65: 1171-1177.
48. Zhu L, Lin J, Ma J, Cronan JE, Wang H. 2010. Triclosan resistance of Pseudomonas aeruginosa PAO1 is due to FabV, a triclosan-resistant enoyl-acyl carrier protein reductase. Antimicrob. Agents Chemother. 54: 689-698.
49. Zhu YG, Johnson TA, Su JQ, Qiao M, Guo GX, Stedtfeld RD, et al. 2013. Diverse and abundant antibiotic resistance genes in Chinese swine farms. Proc. Natl. Acad. Sci. USA 110: 3435-3440.