-
1
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA (2000) The hallmarks of cancer. Cell 100(1):57-70.
-
(2000)
Cell
, vol.100
, Issue.1
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
2
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: The next generation. Cell 144(5):646-674.
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
3
-
-
0030576517
-
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis
-
Hanahan D, Folkman J (1996) Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis. Cell 86(3):353-364.
-
(1996)
Cell
, vol.86
, Issue.3
, pp. 353-364
-
-
Hanahan, D.1
Folkman, J.2
-
4
-
-
77955928161
-
Tumors as organs: Complex tissues that interface with the entire organism
-
Egeblad M, Nakasone ES, Werb Z (2010) Tumors as organs: Complex tissues that interface with the entire organism. Dev Cell 18(6):884-901.
-
(2010)
Dev Cell
, vol.18
, Issue.6
, pp. 884-901
-
-
Egeblad, M.1
Nakasone, E.S.2
Werb, Z.3
-
5
-
-
77955893559
-
Unraveling the obesity and breast cancer links: A role for cancer-associated adipocytes?
-
Dirat B, Bochet L, Escourrou G, Valet P, Muller C (2010) Unraveling the obesity and breast cancer links: A role for cancer-associated adipocytes? Endocr Dev 19:45-52.
-
(2010)
Endocr Dev
, vol.19
, pp. 45-52
-
-
Dirat, B.1
Bochet, L.2
Escourrou, G.3
Valet, P.4
Muller, C.5
-
6
-
-
33646384428
-
Fibroblasts in cancer
-
Kalluri R, Zeisberg M (2006) Fibroblasts in cancer. Nat Rev Cancer 6(5):392-401.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.5
, pp. 392-401
-
-
Kalluri, R.1
Zeisberg, M.2
-
7
-
-
77950931419
-
Matrix metalloproteinases: Regulators of the tumor microenvironment
-
Kessenbrock K, Plaks V, Werb Z (2010) Matrix metalloproteinases: Regulators of the tumor microenvironment. Cell 141(1):52-67.
-
(2010)
Cell
, vol.141
, Issue.1
, pp. 52-67
-
-
Kessenbrock, K.1
Plaks, V.2
Werb, Z.3
-
8
-
-
77954563614
-
Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity
-
DeNardo DG, Andreu P, Coussens LM (2010) Interactions between lymphocytes and myeloid cells regulate pro- versus anti-tumor immunity. Cancer Metastasis Rev 29(2):309-316.
-
(2010)
Cancer Metastasis Rev
, vol.29
, Issue.2
, pp. 309-316
-
-
DeNardo, D.G.1
Andreu, P.2
Coussens, L.M.3
-
9
-
-
77950346282
-
Immunity, inflammation, and cancer
-
Grivennikov SI, Greten FR, Karin M (2010) Immunity, inflammation, and cancer. Cell 140(6):883-899.
-
(2010)
Cell
, vol.140
, Issue.6
, pp. 883-899
-
-
Grivennikov, S.I.1
Greten, F.R.2
Karin, M.3
-
10
-
-
77950950894
-
Macrophage diversity enhances tumor progression and metastasis
-
Qian BZ, Pollard JW (2010) Macrophage diversity enhances tumor progression and metastasis. Cell 141(1):39-51.
-
(2010)
Cell
, vol.141
, Issue.1
, pp. 39-51
-
-
Qian, B.Z.1
Pollard, J.W.2
-
11
-
-
30144443269
-
Paradoxical roles of the immune system during cancer development
-
de Visser KE, Eichten A, Coussens LM (2006) Paradoxical roles of the immune system during cancer development. Nat Rev Cancer 6(1):24-37.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.1
, pp. 24-37
-
-
De Visser, K.E.1
Eichten, A.2
Coussens, L.M.3
-
12
-
-
47949090079
-
The role of myeloid cells in the promotion of tumour angiogenesis
-
Murdoch C, Muthana M, Coffelt SB, Lewis CE (2008) The role of myeloid cells in the promotion of tumour angiogenesis. Nat Rev Cancer 8(8):618-631.
-
(2008)
Nat Rev Cancer
, vol.8
, Issue.8
, pp. 618-631
-
-
Murdoch, C.1
Muthana, M.2
Coffelt, S.B.3
Lewis, C.E.4
-
13
-
-
0036839143
-
Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes
-
Mantovani A, Sozzani S, Locati M, Allavena P, Sica A (2002) Macrophage polarization: Tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes. Trends Immunol 23(11):549-555.
-
(2002)
Trends Immunol
, vol.23
, Issue.11
, pp. 549-555
-
-
Mantovani, A.1
Sozzani, S.2
Locati, M.3
Allavena, P.4
Sica, A.5
-
14
-
-
33645991795
-
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy
-
Sica A, Schioppa T, Mantovani A, Allavena P (2006) Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: Potential targets of anti-cancer therapy. Eur J Cancer 42(6):717-727.
-
(2006)
Eur J Cancer
, vol.42
, Issue.6
, pp. 717-727
-
-
Sica, A.1
Schioppa, T.2
Mantovani, A.3
Allavena, P.4
-
15
-
-
47949096781
-
Cancer-related inflammation
-
Mantovani A, Allavena P, Sica A, Balkwill F (2008) Cancer-related inflammation. Nature 454(7203):436-444.
-
(2008)
Nature
, vol.454
, Issue.7203
, pp. 436-444
-
-
Mantovani, A.1
Allavena, P.2
Sica, A.3
Balkwill, F.4
-
16
-
-
41149136843
-
Polarized immune responses differentially regulate cancer development
-
Johansson M, Denardo DG, Coussens LM (2008) Polarized immune responses differentially regulate cancer development. Immunol Rev 222:145-154.
-
(2008)
Immunol Rev
, vol.222
, pp. 145-154
-
-
Johansson, M.1
Denardo, D.G.2
Coussens, L.M.3
-
17
-
-
77956976681
-
Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm
-
Biswas SK, Mantovani A (2010) Macrophage plasticity and interaction with lymphocyte subsets: Cancer as a paradigm. Nat Immunol 11(10):889-896.
-
(2010)
Nat Immunol
, vol.11
, Issue.10
, pp. 889-896
-
-
Biswas, S.K.1
Mantovani, A.2
-
18
-
-
84860484044
-
Tumor-associated neutrophils: Friend or foe?
-
Fridlender ZG, Albelda SM (2012) Tumor-associated neutrophils: Friend or foe? Carcinogenesis 33(5):949-955.
-
(2012)
Carcinogenesis
, vol.33
, Issue.5
, pp. 949-955
-
-
Fridlender, Z.G.1
Albelda, S.M.2
-
19
-
-
84855817522
-
Immunology in the clinic review series; Focus on cancer: Tumour-associated macrophages: Undisputed stars of the inflammatory tumour microenvironment
-
Allavena P, Mantovani A (2012) Immunology in the clinic review series; Focus on cancer: Tumour-associated macrophages: Undisputed stars of the inflammatory tumour microenvironment. Clin Exp Immunol 167(2):195-205.
-
(2012)
Clin Exp Immunol
, vol.167
, Issue.2
, pp. 195-205
-
-
Allavena, P.1
Mantovani, A.2
-
20
-
-
58149267580
-
Corrupt policemen: Inflammatory cells promote tumor angiogenesis
-
Zumsteg A, Christofori G (2009) Corrupt policemen: Inflammatory cells promote tumor angiogenesis. Curr Opin Oncol 21(1):60-70.
-
(2009)
Curr Opin Oncol
, vol.21
, Issue.1
, pp. 60-70
-
-
Zumsteg, A.1
Christofori, G.2
-
21
-
-
39049126521
-
Tie2-expressing monocytes: Regulation of tumor angiogenesis and therapeutic implications
-
De Palma M, Murdoch C, Venneri MA, Naldini L, Lewis CE (2007) Tie2-expressing monocytes: Regulation of tumor angiogenesis and therapeutic implications. Trends Immunol 28(12):519-524.
-
(2007)
Trends Immunol
, vol.28
, Issue.12
, pp. 519-524
-
-
De Palma, M.1
Murdoch, C.2
Venneri, M.A.3
Naldini, L.4
Lewis, C.E.5
-
22
-
-
77953268611
-
Alternative activation of macrophages: Mechanism and functions
-
Gordon S, Martinez FO (2010) Alternative activation of macrophages: Mechanism and functions. Immunity 32(5):593-604.
-
(2010)
Immunity
, vol.32
, Issue.5
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
23
-
-
84857141296
-
Cancer-related inflammation: Common themes and therapeutic opportunities
-
Balkwill FR, Mantovani A (2012) Cancer-related inflammation: Common themes and therapeutic opportunities. Semin Cancer Biol 22(1):33-40.
-
(2012)
Semin Cancer Biol
, vol.22
, Issue.1
, pp. 33-40
-
-
Balkwill, F.R.1
Mantovani, A.2
-
24
-
-
33748301967
-
Bioimmunotherapy for melanoma using fully human antibodies targeting MCAM/MUC18 and IL-8
-
Melnikova VO, Bar-Eli M (2006) Bioimmunotherapy for melanoma using fully human antibodies targeting MCAM/MUC18 and IL-8. Pigment Cell Res 19(5):395-405.
-
(2006)
Pigment Cell Res
, vol.19
, Issue.5
, pp. 395-405
-
-
Melnikova, V.O.1
Bar-Eli, M.2
-
25
-
-
43749084585
-
Recent advances in cancer stem cells
-
Cho RW, Clarke MF (2008) Recent advances in cancer stem cells. Curr Opin Genet Dev 18(1):48-53.
-
(2008)
Curr Opin Genet Dev
, vol.18
, Issue.1
, pp. 48-53
-
-
Cho, R.W.1
Clarke, M.F.2
-
26
-
-
75149178349
-
Tumor metabolism of lactate: The influence and therapeutic potential for MCT and CD147 regulation
-
Kennedy KM, Dewhirst MW (2010) Tumor metabolism of lactate: The influence and therapeutic potential for MCT and CD147 regulation. Future Oncol 6(1):127-148.
-
(2010)
Future Oncol
, vol.6
, Issue.1
, pp. 127-148
-
-
Kennedy, K.M.1
Dewhirst, M.W.2
-
27
-
-
79952528125
-
CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth
-
Ishimoto T, et al. (2011) CD44 variant regulates redox status in cancer cells by stabilizing the xCT subunit of system xc(-) and thereby promotes tumor growth. Cancer Cell 19(3):387-400.
-
(2011)
Cancer Cell
, vol.19
, Issue.3
, pp. 387-400
-
-
Ishimoto, T.1
-
28
-
-
69549114870
-
Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells
-
Chan KS, et al. (2009) Identification, molecular characterization, clinical prognosis, and therapeutic targeting of human bladder tumor-initiating cells. Proc Natl Acad Sci USA 106(33):14016-14021.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.33
, pp. 14016-14021
-
-
Chan, K.S.1
-
30
-
-
80053200887
-
Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer
-
Eruslanov E, et al. (2012) Circulating and tumor-infiltrating myeloid cell subsets in patients with bladder cancer. Int J Cancer 130(5):1109-1119.
-
(2012)
Int J Cancer
, vol.130
, Issue.5
, pp. 1109-1119
-
-
Eruslanov, E.1
-
31
-
-
34247638102
-
Chronic inflammation and bladder cancer
-
Michaud DS (2007) Chronic inflammation and bladder cancer. Urol Oncol 25(3):260-268.
-
(2007)
Urol Oncol
, vol.25
, Issue.3
, pp. 260-268
-
-
Michaud, D.S.1
-
32
-
-
84857134689
-
Three differentiation states risk-stratify bladder cancer into distinct subtypes
-
Volkmer JP, et al. (2012) Three differentiation states risk-stratify bladder cancer into distinct subtypes. Proc Natl Acad Sci USA 109(6):2078-2083.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.6
, pp. 2078-2083
-
-
Volkmer, J.P.1
-
33
-
-
0017276076
-
In vitro cultivation of epithelial cells derived from tumors of the human urinary tract
-
Elliott AY, Bronson DL, Stein N, Fraley EE (1976) In vitro cultivation of epithelial cells derived from tumors of the human urinary tract. Cancer Res 36(2 Pt 1):365-369.
-
(1976)
Cancer Res
, vol.36
, Issue.2
, pp. 365-369
-
-
Elliott, A.Y.1
Bronson, D.L.2
Stein, N.3
Fraley, E.E.4
-
34
-
-
84877004454
-
Cytokine patterns in patients with cancer: A systematic review
-
Lippitz BE (2013) Cytokine patterns in patients with cancer: A systematic review. Lancet Oncol 14(6):e218-e228.
-
(2013)
Lancet Oncol
, vol.14
, Issue.6
, pp. e218-e228
-
-
Lippitz, B.E.1
-
35
-
-
79954430750
-
Serum biomarkers for improved diagnostic of pancreatic cancer: A current overview
-
Bünger S, Laubert T, Roblick UJ, Habermann JK (2011) Serum biomarkers for improved diagnostic of pancreatic cancer: A current overview. J Cancer Res Clin Oncol 137(3):375-389.
-
(2011)
J Cancer Res Clin Oncol
, vol.137
, Issue.3
, pp. 375-389
-
-
Bünger, S.1
Laubert, T.2
Roblick, U.J.3
Habermann, J.K.4
-
36
-
-
72149092392
-
MB49 murine urothelial carcinoma: Molecular and phenotypic comparison to human cell lines as a model of the direct tumor response to bacillus Calmette-Guerin
-
Chen F, Zhang G, Cao Y, Hessner MJ, See WA (2009) MB49 murine urothelial carcinoma: Molecular and phenotypic comparison to human cell lines as a model of the direct tumor response to bacillus Calmette-Guerin. J Urol 182(6):2932-2937.
-
(2009)
J Urol
, vol.182
, Issue.6
, pp. 2932-2937
-
-
Chen, F.1
Zhang, G.2
Cao, Y.3
Hessner, M.J.4
See, W.A.5
-
37
-
-
2442667692
-
Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor microenvironment
-
Loskog A, et al. (2004) Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor microenvironment. J Immunol 172(11):7200-7205.
-
(2004)
J Immunol
, vol.172
, Issue.11
, pp. 7200-7205
-
-
Loskog, A.1
-
38
-
-
1542267863
-
Interleukin-12 immunotherapy of murine transitional cell carcinoma of the bladder: Dose dependent tumor eradication and generation of protective immunity
-
O'Donnell MA, et al. (2004) Interleukin-12 immunotherapy of murine transitional cell carcinoma of the bladder: Dose dependent tumor eradication and generation of protective immunity. J Urol 171(3):1330-1335.
-
(2004)
J Urol
, vol.171
, Issue.3
, pp. 1330-1335
-
-
O'Donnell, M.A.1
-
40
-
-
78649434143
-
CD14 is a coreceptor of Toll-like receptors 7 and 9
-
Baumann CL, et al. (2010) CD14 is a coreceptor of Toll-like receptors 7 and 9. J Exp Med 207(12):2689-2701.
-
(2010)
J Exp Med
, vol.207
, Issue.12
, pp. 2689-2701
-
-
Baumann, C.L.1
-
41
-
-
84880920680
-
Tumor microenvironment and myeloid-derived suppressor cells
-
Umansky V, Sevko A (2013) Tumor microenvironment and myeloid-derived suppressor cells. Cancer Microenviron 6(2):169-177.
-
(2013)
Cancer Microenviron
, vol.6
, Issue.2
, pp. 169-177
-
-
Umansky, V.1
Sevko, A.2
-
42
-
-
84872559040
-
The immunosuppressive tumour network: Myeloid-derived suppressor cells, regulatory T cells and natural killer T cells
-
Lindau D, Gielen P, Kroesen M, Wesseling P, Adema GJ (2013) The immunosuppressive tumour network: Myeloid-derived suppressor cells, regulatory T cells and natural killer T cells. Immunology 138(2):105-115.
-
(2013)
Immunology
, vol.138
, Issue.2
, pp. 105-115
-
-
Lindau, D.1
Gielen, P.2
Kroesen, M.3
Wesseling, P.4
Adema, G.J.5
-
43
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak HF (1986) Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 315(26):1650-1659.
-
(1986)
N Engl J Med
, vol.315
, Issue.26
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
44
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z (2002) Inflammation and cancer. Nature 420(6917):860-867.
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
45
-
-
40649109728
-
The wolf in sheep's clothing: The role of interleukin-6 in immunity, inflammation and cancer
-
Naugler WE, Karin M (2008) The wolf in sheep's clothing: The role of interleukin-6 in immunity, inflammation and cancer. Trends Mol Med 14(3):109-119.
-
(2008)
Trends Mol Med
, vol.14
, Issue.3
, pp. 109-119
-
-
Naugler, W.E.1
Karin, M.2
-
46
-
-
58649101347
-
gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis
-
Bollrath J, et al. (2009) gp130-mediated Stat3 activation in enterocytes regulates cell survival and cell-cycle progression during colitis-associated tumorigenesis. Cancer Cell 15(2):91-102.
-
(2009)
Cancer Cell
, vol.15
, Issue.2
, pp. 91-102
-
-
Bollrath, J.1
-
48
-
-
84862304990
-
Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells
-
Wang Y, et al. (2012) Interleukin-6 signaling regulates anchorage-independent growth, proliferation, adhesion and invasion in human ovarian cancer cells. Cytokine 59(2):228-236.
-
(2012)
Cytokine
, vol.59
, Issue.2
, pp. 228-236
-
-
Wang, Y.1
-
49
-
-
84861709168
-
Interleukin-8 secretion by ovarian cancer cells increases anchorage-independent growth, proliferation, angiogenic potential, adhesion and invasion
-
Wang Y, et al. (2012) Interleukin-8 secretion by ovarian cancer cells increases anchorage-independent growth, proliferation, angiogenic potential, adhesion and invasion. Cytokine 59(1):145-155.
-
(2012)
Cytokine
, vol.59
, Issue.1
, pp. 145-155
-
-
Wang, Y.1
-
50
-
-
84867605321
-
STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation
-
Tye H, et al. (2012) STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation. Cancer Cell 22(4):466-478.
-
(2012)
Cancer Cell
, vol.22
, Issue.4
, pp. 466-478
-
-
Tye, H.1
-
51
-
-
68349130145
-
Blocking TLR2 activity attenuates pulmonary metastases of tumor
-
Yang HZ, et al. (2009) Blocking TLR2 activity attenuates pulmonary metastases of tumor. PLoS ONE 4(8):e6520.
-
(2009)
PLoS ONE
, vol.4
, Issue.8
, pp. e6520
-
-
Yang, H.Z.1
-
52
-
-
20444432334
-
Toll-like receptors on tumor cells facilitate evasion of immune surveillance
-
Huang B, et al. (2005) Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res 65(12):5009-5014.
-
(2005)
Cancer Res
, vol.65
, Issue.12
, pp. 5009-5014
-
-
Huang, B.1
-
53
-
-
79953746223
-
Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder
-
Shin K, et al. (2011) Hedgehog/Wnt feedback supports regenerative proliferation of epithelial stem cells in bladder. Nature 472(7341):110-114.
-
(2011)
Nature
, vol.472
, Issue.7341
, pp. 110-114
-
-
Shin, K.1
|