Is vitamin D status a determining factor for metabolic syndrome? A case-control study

Diabetes, Metabolic Syndrome and Obesity

Volumn 4, Issue , 2011, Pages 205-212

  Salekzamani, Shabnam ^a   Neyestani, Tirang R ^a   Alavi Majd, Hamid ^a   Houshiarrad, Anahita ^a   Kalayi, Ali ^a   Shariatzadeh, Nastaran ^a   Gharavi, A’Azam ^a  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Inflammation; Metabolic syndrome; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; C REACTIVE PROTEIN; GLUCOSE; OSTEOCALCIN; PARATHYROID HORMONE;

ADULT; ANTHROPOMETRY; ARTICLE; BODY FAT; BODY MASS; CALCIUM BLOOD LEVEL; CASE CONTROL STUDY; CONTROLLED STUDY; DEMOGRAPHY; FAT MASS; FEMALE; GLUCOSE BLOOD LEVEL; GROUPS BY AGE; HEALTH PROGRAM; HOMEOSTASIS MODEL ASSESSMENT; HUMAN; INFLAMMATION; LABORATORY TEST; MAJOR CLINICAL STUDY; METABOLIC SYNDROME X; PARATHYROID HORMONE BLOOD LEVEL; PREDICTOR VARIABLE; PREMENOPAUSE; PROTEIN BLOOD LEVEL; VITAMIN BLOOD LEVEL; VITAMIN D METABOLISM; WAIST CIRCUMFERENCE; WAIST HIP RATIO;

EID: 84928129857     PISSN: None     EISSN: 11787007     Source Type: Journal    
DOI: 10.2147/DMSO.S21061     Document Type: Article

References (64)

1. Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel III) final report. Circulation. 2002;106(25):3143–3421.
2. Despres JP, Lemieux I, Bergeron J, et al. Abdominal obesity and the metabolic syndrome: contribution to global cardiometabolic risk. Arterioscler Thromb Vasc Biol. 2008;28(6):1039–1049.
3. Elks CM, Francis J. Central adiposity, systemic inflammation, and the metabolic syndrome. Curr Hypertens Rep. 2010;12(2):99–104.
4. Kressel G, Trunz B, Bub A, et al. Systemic and vascular markers of inflammation in relation to metabolic syndrome and insulin resistance in adults with elevated atherosclerosis risk. Atherosclerosis. 2009; 202(1):263–271.
5. Neyestani TR, Salekzamani S, Kalayi A, et al. Predictors of serum levels of high sensitivity C-reactive protein and systolic blood pressure in overweight and obese nondiabetic women in Tehran: a cross-sectional study. Metab Syndr Relat Disord. 2011;9(1):41–47.
6. Manolopoulos KN, Karpe F, Frayn KN. Gluteofemoral body fat as a determinant of metabolic health. Int J Obes (Lond). 2010;34(6): 949–959.
7. Wortsman J, Matsuoka LY, Chen TC, Lu Z, Holick MF. Decreased bioavail-ability of vitamin D in obesity. Am J Clin Nutr. 2000;72(3): 690–693.
8. Boucher BJ. Inadequate vitamin D status: does it contribute to the disorders comprising syndrome “X”? Br J Nutr. 1998;79(4):315–327.
9. Chiu KC, Chu A, Go VL, Saad MF. Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am J Clin Nutr. 2004; 79(5):820–825.
10. Liu S, Song Y, Ford ES, Manson JE, Buring JE, Ridker PM. Dietary calcium, vitamin D, and the prevalence of metabolic syndrome in middle-aged and older US women. Diabetes Care. 2005;28(12):2926–2932.
11. Florentin M, Elisaf MS, Mikhailidis DP, Liberopoulos EN. Vitamin D and metabolic syndrome: is there a link? Curr Pharm Des. 2010; 16(30):3417–3434.
12. Kayaniyil S, Vieth R, Harris SB, et al. Association of 25(OH)D and PTH with metabolic syndrome and its traditional and nontraditional components. J Clin Endocrinol Metab. 2011;96(1):168–175.
13. Skjodt H, Gallagher JA, Beresford JN, Couch M, Poser JW, Russell RG. Vitamin D metabolites regulate osteocalcin synthesis and proliferation of human bone cells in vitro. J Endocrinol. 1985;105(3):391–396.
14. Bae SJ, Choe JW, Chung YE, et al. The association between serum osteocalcin levels and metabolic syndrome in Koreans. Osteoporos Int. December 9, 2010. [Epub ahead of print].
15. Saleem U, Mosley TH Jr, Kullo IJ. Serum osteocalcin is associated with measures of insulin resistance, adipokine levels, and the presence of metabolic syndrome. Arterioscler Thromb Vasc Biol. 2010;30(7): 1474–1478.
16. Guillot X, Semerano L, Saidenberg-Kermanac’h N, Falgarone G, Boissier MC. Vitamin D and inflammation. Joint Bone Spine. 2010; 77(6):552–557.
17. Cancello R, Clement K. Is obesity an inflammatory illness? Role of low-grade inflammation and macrophage infiltration in human white adipose tissue. BJOG. 2006;113(10):1141–1147.
18. Amiri F. Metabolic syndrome, insulin resistance and oxidative stress: adding insights to improve cardiovascular prevention. J Hypertens. 2009;27(7):1352–1354.
19. Pischon T, Hu FB, Rexrode KM, Girman JC, Manson AE, Rimm EB. Inflammation, the metabolic syndrome, and risk of coronary heart disease in women and men. Atherosclerosis. 2008;197(1):392–399.
20. Barbarroja N, Lopez-Pedrera R, Mayas MD, et al. The obese healthy paradox: is inflammation the answer? Biochem J. 2010;430(1):141–149.
21. Jablonski KL, Chonchol M, Pierce GL, Walker AE, Seals DR. 25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension. 2011;57(1):63–69.
22. Yiu YF, Chan YH, Yiu KH, et al. Vitamin D deficiency is associated with depletion of circulating endothelial progenitor cells and endothelial dysfunction in patients with type 2 diabetes. J Clin Endocrinol Metab. 2011;96(5):E830–E835.
23. Peng X, Vaishnav A, Murillo G, Alimirah F, Torres KE, Mehta RG. Protection against cellular stress by 25-hydroxy vitamin D3 in breast epithelial cells. J Cell Biochem. 2010;110(6):1324–1333.
24. Sun X, MB. Z. 1alpha,25-dihydroxyvitamin D3 modulation of adipocyte reactive oxygen species production. Obesity. 2007;15(8):1944–1953.
25. Kelishadi R, Gharipour M, Sadri GH, Tavasoli AA, Amani A. Cardiovascular disease risk factors, metabolic syndrome and obesity in an Iranian population. East Mediterr Health J. 2008;14(5):1070–1079.
26. Brustad MAE, Engelsen O, Aksnes L, Lund E. Vitamin D status of middle-aged women at 65–71 degrees N in relation to dietary intake and exposure to ultraviolet radiation. Public Health Nutr. 2003;7(2): 327–334.
27. Matthews DR, JP. H. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentration in man. Diabetologia. 1985;28(7):412–419.
28. Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin Chim Acta. 1978;90(1):37–43.
29. Neyestani TR, Shariatzadeh A, Gharavi A, Kalayi A, Khalaj N. Physiological dose of lycopene suppressed oxidative stress and enhanced serum levels of immunoglobolin M in patients with type 2 diabetes mellitus: a possible role in the prevention of long-term complications. J Endocrinol Invest. 2007;30(10):833–938.
30. Neyestani TR, Fereydouni Z, Hejazi S, et al. Vitamin C status in Iranian children with acute lymphoblastic leukemia: evidence for increased utilization. J Pediatr Gastroenterol Nutr. 2007;45(1):141–144.
31. Neyestani TR, Gharavi A, Kalayi A. Determination of serum 25-hydroxy cholecalciferol using high-performance liquid chromatography: a reliable tool for assessment of vitamin D status. Int J Vitam Nutr Res. 2007;77(5):341–346.
32. Saintonge S, Bang H, Gerber LM. Implications of a new definition of vitamin D deficiency in a multiracial US adolescent population: the National Health and Nutrition Examination Survey (III). Pediatrics. 2009;123(3):797–803.
33. Hsu CS, Liu CJ, Liu CH, et al. High hepatitis C viral load is associated with insulin resistance in patients with chronic hepatitis C. Liver Int. 2008;28(2):271–277.
34. Chandalia M, Abate N. Metabolic complications of obesity: inflated or inflamed? J Diabetes Complications. 2007;21(2):128–136.
35. Chandalia M, Lin P, Seenivasan T, et al. Insulin resistance and body fat distribution in South Asian men compared to Caucasian men. PLoS One. 2007;2(8):e812.
36. Aasheim ET, Hofso D, Hjelmeseth J, Birkeland KI, Bohmer T. Vitamin status in morbidly obese patients: a cross-sectional study. Am J Clin Nutr. 2008;87(2):362–369.
37. Boucher B. Inadequate vitamin D status: does it contribute to the disorders comprising syndrome ‘‘X’’. Br J Nutr. 1998;79(4):315–327.
38. Patel P, Poretsky L, Liao E. Lack of effect of subtherapeutic vitamin D treatment on glycemic and lipid parameters in type 2 diabetes: a pilot prospective randomized trial. Journal of Diabetes. 2010;2(1):36–40.
39. Pittas AG HSS, Stark PC, Dawson-Hughes B. The effects of calcium and vitamin D supplementation on blood glucose and markers of inflammation in nondiabetic adults. Diabetes Care. 2007;30(4): 980–986.
40. Nikooyeh B, Neyestani TR, Farvid M, et al. Daily consumption of vitamin D− or vitamin D+ calcium-fortified yogurt drink improved glycemic control in patients with type 2 diabetes: a randomized clinical trial. Am J Clin Nutr. 2011;93(4):764–771.
41. Bourlon P, Billaudel B, Faure-Dussert A. Influence of vitamin D3 deficiency and 1,25 dihydroxyvitamin D3 on de novo insulin biosyn-thesis in the islets of the rat endocrine pancreas. J Endocrinol. 1999; 160(1):87–95.
42. Maestro B CJ, Davila N, Calle C. Stimulation by 1,25-dihydroxyvitamin D3 of insulin receptor expression and insulin responsiveness for glucose transport in U-937 human promonocytic cells. Endocr J. 2000;47(4): 383–391.
43. McGill AT, Stewart JM, Lithander FE, Strik CM, Poppitt SD. Relationships of low serum vitamin D3 with anthropometry and markers of the metabolic syndrome and diabetes in overweight and obesity. Nutr J. 2008;7:4.
44. Ford ES, Ajani UA, McGuire LC, Liu S. Concentrations of serum vitamin D and the metabolic syndrome among US adults. Diabetes Care. 2005;28(5):1228–1230.
45. Hjelmesæth J, Hofsø D, Aasheim ET, et al. Parathyroid hormone, but not vitamin D, is associated with the metabolic syndrome in morbidly obese women and men: a cross-sectional study. Cardiovasc Diabetol. 2009;8:7.
46. Reis JP, von Muhlen D, Miller ER 3rd. Relation of 25-hydroxyvitamin D and parathyroid hormone levels with metabolic syndrome among US adults. Eur J Endocrinol. 2008;159(1):41–48.
47. Rueda S, Fernández-Fernández C, Romero F, Osaba MJ, Vidal J. Vitamin D, PTH, and the metabolic syndrome in severely obese subjects. Obes Surg. 2008;18(2):151–154.
48. Reis JP, von Muhlen D, Kritz-Silverstein D, Wingard DL, Barrett-Connor E. Vitamin D, parathyroid hormone levels, and the prevalence of metabolic syndrome in community-dwelling older adults. Diabetes Care. 2007;30(6):1549–1555.
49. Majumdar V, Nagaraja D, Christopher R. Vitamin D status and metabolic syndrome in Asian Indians. Int J Obes (Lond). November 9, 2010. [Epub ahead of print].
50. Pinelli NR, Jaber LA, Brown MB, Herman WH. Serum 25-hydroxy vitamin D and insulin resistance, metabolic syndrome, and glucose intolerance among Arab Americans. Diabetes Care. 2010;33(6): 1373–1375.
51. Yeap BB, Chubb SA, Flicker L, et al. Reduced serum total osteocalcin is associated with metabolic syndrome in older men via waist circumference, hyperglycemia, and triglyceride levels. Eur J Endocrinol. 2010; 163(2):265–272.
52. Tan A, Gao Y, Yang X, et al. Low serum osteocalcin level is a potential marker for metabolic syndrome: results from a Chinese male population survey. Metabolism. February 23, 2010. doi: 10.1016/j.metabol.2011.01.002.
53. Blaha MJ, Gebretsadik T, Shintani A, Elasy TA. Waist circumference, not the metabolic syndrome, predicts glucose deterioration in type 2 diabetes. Obesity (Silver Spring). 2008;16(4):869–874.
54. Berg AH, Scherer PE. Adipose tissue, inflammation, and cardiovascular disease. Circ Res. 2005;96(9):939–949.
55. Fontana L, Eagon JC, Trujillo ME, Scherer PE, Klein S. Visceral fat adipokine secretion is associated with systemic inflammation in obese humans. Diabetes. 2007;56(4):1010–1013.
56. Karelis AD, Faraj M, Bastard JP, et al. The metabolically healthy but obese individual presents a favorable inflammation profile. J Clin Endocrinol Metab. 2005;90(7):4145–4150.
57. Esposito K, Giugliano D. The metabolic syndrome and inflammation: association or causation? Nutr Metab Cardiovasc Dis. 2004;14(5): 228–232.
58. Kloting N, Fasshauer M, Dietrich A, et al. Insulin-sensitive obesity. Am J Physiol Endocrinol Metab. 2010;299(3):E506–E515.
59. Esmaillzadeh A, Kimiagar M, Mehrabi Y, Azadbakht L, Hu FB, Willett WC. Fruit and vegetable intakes, C-reactive protein, and the metabolic syndrome. Am J Clin Nutr. 2006;84(6):1489–1497.
60. Azadbakht L, Esmaillzadeh A. Red meat intake is associated with metabolic syndrome and the plasma C-reactive protein concentration in women. J Nutr. 2009;139(2):335–339.
61. Esmaillzadeh A, Azadbakht L. Dairy consumption and circulating levels of inflammatory markers among Iranian women. Public Health Nutr. 2010;13(9):1395–1402.
62. Esmaillzadeh A, Azadbakht L. Consumption of hydrogenated versus nonhydrogenated vegetable oils and risk of insulin resistance and the metabolic syndrome among Iranian adult women. Diabetes Care. 2008;31(2):223–226.
63. Krishnan AV, Feldman D. Mechanisms of the anti-cancer and anti-inflammatory actions of vitamin D. Annu Rev Pharmacol Toxicol. 2011;51:311–336.
64. Hoeck AD, Pall ML. Will vitamin D supplementation ameliorate diseases characterized by chronic inflammation and fatigue? Med Hypotheses. 2011;76(2):208–213.