Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Angiology

Volumn 66, Issue 5, 2015, Pages 441-447

  Çiçek, Gökhan ^a   Açikgoz, Sadik Kadri ^b   Bozbay, Mehmet ^c   Altay, Servet ^d   Uʇur, Murat ^e   Uluganyan, Mahmut ^f   Uyarel, Huseyin ^g  

^a ANKARA TRAINING AND RESEARCH HOSPITAL   (Turkey)

^b TURKIYE YUKSEK IHTISAS HOSPITAL   (Turkey)

^c MARMARA UNIVERSITY   (Turkey)

^d Edirne State Hospital   (Turkey)

^e DR SIYAMI ERSEK THORACIC AND CARDIOVASCULAR SURGERY TRAINING AND RESEARCH HOSPITAL   (Turkey)

^f Kadirli State Hospital   (Turkey)

^g BEZMIALEM VAKIF UNIVERSITY   (Turkey)

Author keywords

acute ST segment elevation myocardial infarction; neutrophil lymphocyte ratio; platelet lymphocyte ratio; primary angioplasty

Indexed keywords

ACETYLSALICYLIC ACID; CHOLESTEROL; CLOPIDOGREL; FIBRINOGEN RECEPTOR; GLUCOSE; HEMOGLOBIN A1C; HEPARIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; CARDIOVASCULAR RISK; CLINICAL ASSESSMENT; CONTROLLED STUDY; FEMALE; FOLLOW UP; HIGH RISK PATIENT; HIGH RISK POPULATION; HOSPITAL ADMISSION; HUMAN; INTERMEDIATE RISK PATIENT; INTERMEDIATE RISK POPULATION; LOADING DRUG DOSE; LONG TERM CARE; MAJOR CLINICAL STUDY; MALE; MORTALITY; NEUTROPHIL LYMPHOCYTE RATIO; PATIENT IDENTIFICATION; PERCUTANEOUS CORONARY INTERVENTION; PLATELET LYMPHOCYTE RATIO; PROGNOSIS; RECEIVER OPERATING CHARACTERISTIC; SAMPLE; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; SURVIVAL PREDICTION; THROMBOCYTE VOLUME; VENOUS BLOOD; ADVERSE EFFECTS; AREA UNDER THE CURVE; BLOOD; KAPLAN MEIER METHOD; LYMPHOCYTE; LYMPHOCYTE COUNT; MIDDLE AGED; MYOCARDIAL INFARCTION; NEUTROPHIL; PREDICTIVE VALUE; PROPORTIONAL HAZARDS MODEL; RETROSPECTIVE STUDY; RISK FACTOR; THROMBOCYTE; THROMBOCYTE COUNT; TIME; TREATMENT OUTCOME; TURKEY;

ADULT; AGED; AREA UNDER CURVE; BLOOD PLATELETS; FEMALE; HOSPITAL MORTALITY; HUMANS; KAPLAN-MEIER ESTIMATE; LYMPHOCYTE COUNT; LYMPHOCYTES; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; NEUTROPHILS; PERCUTANEOUS CORONARY INTERVENTION; PLATELET COUNT; PREDICTIVE VALUE OF TESTS; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK FACTORS; ROC CURVE; TIME FACTORS; TREATMENT OUTCOME; TURKEY;

EID: 84928042688     PISSN: 00033197     EISSN: 19401574     Source Type: Journal    
DOI: 10.1177/0003319714535970     Document Type: Article

References (48)

1. Ross R. Atherosclerosis - an inflammatory disease. N Engl J Med. 1999 ; 340 (2). 115-126
2. Libby P. What have we learned about the biology of atherosclerosis? The role of inflammation. Am J Cardiol. 2001 ; 88 (7B). 3J - 6J
3. Guasti L, Dentali F, Castiglioni L, et al. Neutrophils and clinical outcomes in patients with acute coronary syndromes and/or cardiac revascularisation. A systematic review on more than 34 000 subjects. Thromb Haemost. 2011 ; 106 (4). 591-599
4. Uthamalingam S, Patvardhan EA, Subramanian S, et al. Utility of the neutrophil to lymphocyte ratio in predicting long-term outcomes in acute decompensated heart failure. Am J Cardiol. 2011 ; 107 (3). 433-438
5. Sen N, Afsar B, Ozcan F, et al. The neutrophil to lymphocyte ratio was associated with impaired myocardial perfusion and long term adverse outcome in patients with ST-elevated myocardial infarction undergoing primary coronary intervention. Atherosclerosis. 2013 ; 228 (1). 203-210
6. Ergelen M, Uyarel H, Altay S, et al. Predictive Value of Elevated Neutrophil to Lymphocyte Ratio in Patients Undergoing Primary Angioplasty for ST-Segment Elevation Myocardial Infarction. Clin Appl Thromb Hemost. 2014 ; 20 (4). 427-432
7. Yildiz A, Yuksel M, Oylumlu M, et al. The utility of the platelet-lymphocyte ratio for predicting no reflow in patients with st-segment elevation myocardial infarction. Clin Appl Thromb Hemost. 2015 ; 21 (3). 223-228
8. Azab B, Shah N, Akerman M, McGinn JT Jr. Value of platelet/lymphocyte ratio as a predictor of all-cause mortality after non- ST-elevation myocardial infarction. J Thromb Thrombolysis. 2012 ; 34 (3). 326-334
9. Cheitlin MD, Armstrong WF, Aurigemma GP, et al. ACC/AHA/ASE 2003 guideline update for the clinical application of echocardiography-summary article: a report of the American college of cardiology/American heart association task force on practice guidelines (ACC/AHA/ASE committee to update the 1997 guidelines for the clinical application of echocardiography). J Am Coll Cardiol. 2003 ; 42 (5). 954-970
10. Thygesen K, Alpert JS, Jaffe AS, et al. Third universal definition of myocardial infarction. Circulation. 2012 ; 126 (16). 2020-2035
11. Gibson CM, Cannon CP, Murphy SA, et al. Relationship of TIMI myocardial perfusion grade to mortality after administration of thrombolytic drugs. Circulation. 2000 ; 101 (2). 125-130
12. Takahashi T, Hiasa Y, Ohara Y, et al. Relation between neutrophil counts on admission, microvascular injury, and left ventricular functional recovery in patients with an anterior wall first acute myocardial infarction treated with primary coronary angioplasty. Am J Cardiol. 2007 ; 100 (1). 35-40
13. Snoep JD, Roest M, Barendrecht AD, De Groot PG, Rosendaal FR, Van Der Bom JG. High platelet reactivity is associated with myocardial infarction in premenopausal women: a population-based case-control study. J Thromb Haemost. 2010 ; 8 (5). 906-913
14. Gul M, Uyarel H, Ergelen M, et al. The relationship between red blood cell distribution width and the clinical outcomes in non-ST elevation myocardial infarction and unstable angina pectoris: a 3-year follow-up. Coron Artery Dis. 2012 ; 23 (5). 330-336
15. Gul M, Uyarel H, Ergelen M, et al. Predictive value of neutrophil to lymphocyte ratio in clinical outcomes of non-st elevation myocardial infarction and unstable angina pectoris: a 3-year follow-up. Clin Appl Thromb Hemost. 2014 ; 20 (4). 378-384
16. Gasparyan AY, Ayvazyan L, Mikhailidis DP, Kitas GD. Mean platelet volume: a link between thrombosis and inflammation?. Curr Pharm Des. 2011 ; 17 (1). 47-58
17. Thomson SP, McMahon LJ, Nugent CA. Endogenous cortisol: a regulator of the number of lymphocytes in peripheral blood. Clin Immunol Immunopathol. 1980 ; 17 (4). 506-514
18. Mehta J, Dinerman J, Mehta P, et al. Neutrophil function in ischemic heart disease. Circulation. 1989 ; 79 (3). 549-556
19. Hansen PR. Role of neutrophils in myocardial ischemia and reperfusion. Circulation. 1995 ; 91 (6). 1872-1885
20. Mehta JL, Nichols WW, Mehta P. Neutrophils as potential participants in acute myocardial ischemia: relevance to reperfusion. J Am Coll Cardiol. 1988 ; 11 (6). 1309-1316
21. Avanzas P, Quiles J, López de Sá E, et al. Neutrophil count and infarct size in patients with acute myocardial infarction. Int J Cardiol. 2004 ; 97 (1). 155-156
22. Kirtane AJ, Bui A, Murphy SA, Barron HV, Gibson CM. Association of peripheral neutrophilia with adverse angiographic outcomes in ST-elevation myocardial infarction. Am J Cardiol. 2004 ; 93 (5). 532-536
23. Thomson SP, Gibbons RJ, Smars PA, et al. Incremental value of the leukocyte differential and the rapid creatine kinase-MB isoenzyme for the early diagnosis of myocardial infarction. Ann Intern Med. 1995 ; 122 (5). 335-341
24. Duffy BK, Gurm HS, Rajagopal V, Gupta R, Ellis SG, Bhatt DL. Usefulness of an elevated neutrophil to lymphocyte ratio in predicting long-term mortality after percutaneous coronary intervention. Am J Cardiol. 2006 ; 97 (7). 993-996
25. Park BJ, Shim JY, Lee HR, et al. Relationship of neutrophil lymphocyte ratio with arterial stiffness and coronary calcium score. Clin Chim Acta. 2011 ; 412 (11-12). 925-929
26. Seo SK, Cho S, Kim HY, et al. Bone mineral density, arterial stiffness, and coronary atherosclerosis in healthy postmenopausal women. Menopause. 2009 ; 16 (5). 937-943
27. Akpek M, Kaya MG, Lam YY, et al. Relation of neutrophil/lymphocyte ratio to coronary flow to in-hospital major adverse cardiac events in patients with ST-elevated myocardial infarction undergoing primary coronary intervention. Am J Cardiol. 2012 ; 110 (5). 621-627
28. Furman MI, Benoit SE, Barnard MR, et al. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol. 1998 ; 31 (2). 352-358
29. Ault KA, Cannon CP, Mitchell J, et al. Platelet activation in patients after an acute coronary syndrome: results from the TIMI-12 trial: thrombolysis in myocardial infarction. J Am Coll Cardiol. 1999 ; 33 (3). 634-639
30. Klinger MH, Jelkmann W. Role of blood platelets in infection and inflammation. J Interferon Cytokine Res. 2002 ; 22 (9). 913-922
31. Alexandrakis MG, Passam FH, Moschandrea IA, et al. Levels of serum cytokines and acute phase proteins in patients with essential and cancer-related thrombocytosis. Am J Clin Oncol. 2003 ; 26 (2). 135-140
32. Gary T, Pichler M, Belaj K, et al. Platelet-to-lymphocyte ratio: a novel marker for critical limb ischemia in peripheral arterial occlusive disease patients. PLoS One. 2013 ; 8 (7). e67688
33. Tsiara S, Elisaf M, Jagroop IA, Mikhailidis DP. Platelets as predictor of vascular risk: is there a practical index of platelet activity?. Clin Appl Thromb Hemost. 2003 ; 9 (3). 177-190
34. Wurtz M, Hvas AM, Kristensen SD, Grove EL. Platelet aggregation is dependent on platelet count in patients with coronary artery disease. Thromb Res. 2012 ; 129 (1). 56-61
35. Lopez-Cuenca AA, Tello-Montoliu A, Roldan V, Perez-Berbel P, Valdes M, Marin F. Prognostic value of mean platelet volume in patients with non-ST-elevation acute coronary syndrome. Angiology. 2012 ; 63 (4). 241-244
36. Elbasan Z, Gür M, Sahin DY, Kuloglu O, Icen YK, Turkoglu C. Association of mean platelet volume and pre-and postinterventional flow with infarct-related artery in ST-segment elevation myocardial infarction. Angiology. 2013 ; 64 (6). 440-446
37. Ozkan B, Uysal OK, Duran M, et al. Relationship between mean platelet volume and atherosclerosis in young patients with ST elevation myocardial infarction. Angiology. 2013 ; 64 (5). 371-374
38. Furman MI, Benoit SE, Barnard MR, et al. Increased platelet reactivity and circulating monocyte-platelet aggregates in patients with stable coronary artery disease. J Am Coll Cardiol. 1998 ; 31 (2). 352-358
39. Zhang SZ, Jin YP, Qin GM, Wang JH. Association of platelet-monocyte aggregates with platelet activation, systemic inflammation, and myocardial injury in patients with non-st elevation acute coronary syndromes. Clin Cardiol. 2007 ; 30 (1). 26-31
40. Zouridakis EG, Garcia-Moll X, Kaski JC. Usefulness of the blood lymphocyte count in predicting recurrent instability and death in patients with unstable angina pectoris. Am J Cardiol. 2000 ; 86 (4). 449-451
41. Ommen SR, Hodge DO, Rodeheffer RJ, McGregor CG, Thomson SP, Gibbons RJ. Predictive power of the relative lymphocyte concentration in patients with advanced heart failure. Circulation. 1998 ; 97 (1). 19-22
42. Nikolsky E, Grines CL, Cox DA, et al. Impact of baseline platelet count in patients undergoing primary percutaneous coronary intervention in acute myocardial infarction (from the CADILLAC trial). Am J Cardiol. 2007 ; 99 (8). 1055-1061
43. Sunbul M, Gerin F, Durmus E, et al. Neutrophil to lymphocyte and platelet to lymphocyte ratio in patients with dipper versus non-dipper hypertension. Clin Exp Hypertens. 2014 ; 36 (4). 217-221
44. Acar G, Kalkan ME, Avci A, et al. The relation of platelet-lymphocyte ratio and coronary collateral circulation in patients with stable angina pectoris and chronic total occlusion [published online October 18, 2013]. Clin Appl Thromb Hemost. 2013.
45. Smith RA, Ghaneh P, Sutton R, Raraty M, Campbell F, Neoptolemos JP. Prognosis of resected ampullary adenocarcinoma by preoperative serum CA19-9 levels and platelet-lymphocyte ratio. J Gastrointest Surg. 2008 ; 12 (8). 1422-1428
46. Raungkaewmanee S, Tangjitgamol S, Manusirivithaya S, Srijaipracharoen S, Thavaramara T. Platelet to lymphocyte ratio as a prognostic factor for epithelial ovarian cancer. J Gynecol Oncol. 2012 ; 23 (4). 265-273
47. Kwon HC, Kim SH, Oh SY, et al. Clinical significance of preoperative neutrophil-lymphocyte versus platelet-lymphocyte ratio in patients with operable colorectal cancer. Biomarkers. 2012 ; 17 (3). 216-222
48. Bhatti I, Peacock O, Lloyd G, Larvin M, Hall RI. Preoperative hematologic markers as independent predictors of prognosis in resected pancreatic ductal adenocarcinoma: neutrophil-lymphocyte versus platelet-lymphocyte ratio. Am J Surg. 2010 ; 200 (2). 197-203