Levels of serum cytokines and acute phase proteins in patients with essential and cancer-related thrombocytosis

American Journal of Clinical Oncology: Cancer Clinical Trials

Volumn 26, Issue 2, 2003, Pages 135-140

  Alexandrakis, Michael G ^a   Passam, Freda H ^a   Moschandrea, Ioanna A ^b   Christophoridou, Anna V ^a   Pappa, Constantina A ^a   Coulocheri, Stavroula A ^c   Kyriakou, Despina S ^d  

^a UNIVERSITY HOSPITAL OF HERAKLION   (Greece)

^b UNIVERSITY OF CRETE   (Greece)

^c UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^d UNIVERSITY HOSPITAL OF LARISSA   (Greece)

Author keywords

Acute phase proteins; Cytokines; Myeloproliferative disorders; Thrombocytosis

Indexed keywords

C REACTIVE PROTEIN; CYTOKINE; FERRITIN; HEMOGLOBIN; INTERLEUKIN 1ALPHA; INTERLEUKIN 2; INTERLEUKIN 6; LACTATE DEHYDROGENASE; PROTEIN; TUMOR NECROSIS FACTOR ALPHA;

ADOLESCENT; ADULT; AGED; ARTICLE; BLOOD LEVEL; CANCER; CHRONIC INFLAMMATION; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; ERYTHROCYTE SEDIMENTATION RATE; FEMALE; HEMATOCRIT; HUMAN; LABORATORY TEST; MALE; MYELOPROLIFERATIVE DISORDER; THROMBOCYTE; THROMBOCYTOSIS;

ACUTE-PHASE PROTEINS; ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BLOOD SEDIMENTATION; CYTOKINES; FEMALE; FERRITINS; HUMANS; L-LACTATE DEHYDROGENASE; MALE; MIDDLE AGED; NEOPLASMS; THROMBOCYTOSIS;

EID: 0037394748     PISSN: 02773732     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000421-200304000-00007     Document Type: Article

References (22)

1. Burkhardt R, Bartl R, Jager K, et al. Working classification of chronic myeloproliferative disorders based on histological, hematological and clinical findings. J Clin Pathol 1986;39:237-52.
2. Mitus AJ, Schafer AI. Thrombocytosis and thrombocythemia. Hematol Oncol Clin North Am 1990;4:157-78.
3. Hoffman R. Regulation of megakaryocytopoiesis. Blood 1986;71:1196-2212.
4. Hsu HC, Tsai WH, Jiang ML, et al. Circulating levels of thrombopoietic and inflammatory cytokines in patients with clonal and reactive thrombocytosis. J Lab Clin Med 1999;134:392-7.
5. Dan K, Gomi S, Inokuchi K, et al. Effects of interleukin-1 and tumor necrosis factor on megakaryocytopoiesis; mechanism of reactive thrombocytosis. Acta Haematol 1995;93:67-72.
6. Alexandrakis MG, Coulocheri SA, Bouros D, et al. Evaluation of inflammatory cytokines in malignant and benign pleural effusions. Oncol Rep 2000;7:1327-32.
7. Moshage H. Cytokines and the hepatic acute phase response. J Pathol 1997;181:257-66.
8. Fibbe WE, Willemze R. The role of interleukin-1 in hematopoiesis. Acta Haematol 1991;86:148-54.
9. Hamagushi H, Takano N, Saito K, et al. Interaction of monocytes and T cells in the regulation of normal human megakaryocytopoiesis in vitro: role of IL-1 and IL-2. Br J Haematol 1990;76:12-20.
10. Colombi M, Radaelli F, Zocchi L, et al. Thrombotic and hemorrhagic complications in essential thrombocythemia: a retrospective study of 103 patients. Cancer 1991;67:2926-30.
11. Tefferi A, Ho TC, Ahmann GJ, et al. Plasma interleukin-6 and C-reactive protein levels in reactive versus clonal thrombocytosis. Am J Med 1994;97:374-8.
12. Haznedaroglu IC, Ertenli I, Ozcebe O, et al. Megakaryocyte-related interleukins in reactive thrombocytosis versus autonomous thrombocythemia. Acta Haematol 1996;95:107-11.
13. Katti J, Wadenvik H. Diagnostic and differential criteria of essential thrombocythemia and reactive thrombocytosis. Leuk Lymphoma 1996;29:41-5.
14. Sayinalp N, Haznedaroglu IC, Ozcebe OI, et al. Interleukin 1-β and interleukin-6 in clonal versus reactive thrombocytosis. Eur J Haematol 1995;55:339-40.
15. Le J, Vilceks J. Tumor necrosis factor and interleukin-1: cytokines with multiple overlapping biological activities. Lab Invest 1987;56:234-48.
16. Suzuki A, Takahashi T, Nakamura K, et al. Thrombocytosis in patients with tumors producing colony-stimulating factor. Blood 1992;80:2052-9.
17. Peschel C, Paul WE, Ohara J, et al. Effects of B cell stimulatory factor-1/interleukin-4 on hematopoietic progenitor cells. Blood 1987;70:254-63.
18. Hirano T. Interleukin-6 and its relation to inflammation and disease. Clin Immunol Immunopathol 1992;62:60-5.
19. Blay J-Y, Fayrot M, Rossi J-F, et al. Role of interleukin-6 in paraneoplastic thrombocytosis. Blood 1993;82:2261-2.
20. Estrov Z, Talpaz M, Mavligit G, et al. Elevated plasma thrombopoietic activity in patients with metastatic cancer-related thrombocytosis. Am J Med 1995;98:551-8.
21. Alexandrakis MG, Coulocheri SA, Bouros D, et al. Evaluation of ferritin, interleukin-6, interleukin-8 and tumor necrosis factor alpha in the differentiation of exudates and transudates in pleural effusions. Anticancer Res 1999;19:3607-12.
22. Engan T, Hannisdal E. Blood analyses as prognostic factors in primary lung cancer. Acta Oncol 1990;29:151-4.