Mode of action of claudin peptidomimetics in the transient opening of cellular tight junction barriers

Biomaterials

Volumn 54, Issue , 2015, Pages 9-20

  Staat, Christian ^a   Coisne, Caroline ^b   Dabrowski, Sebastian ^a   Stamatovic, Svetlana M ^c   Andjelkovic, Anuska V ^c   Wolburg, Hartwig ^d   Engelhardt, Britta ^b   Blasig, Ingolf E ^a  

^a LEIBNIZ INSTITUT FÜR MOLEKULARE PHARMAKOLOGIE   (Germany)

^b UNIVERSITY OF BERN   (Switzerland)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^d UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Brain endothelial cells; Controlled drug release; Endocytosis; Freeze fracture electron microscopy; Peptidomimetics; Tight junction proteins

Indexed keywords

ELECTRON MICROSCOPES; ELECTRON MICROSCOPY; ENDOTHELIAL CELLS; MOLECULAR BIOLOGY; TARGETED DRUG DELIVERY;

CONTROLLED DRUG RELEASE; ENDOCYTOSIS; FREEZE FRACTURE ELECTRON MICROSCOPY; PEPTIDOMIMETICS; TIGHT JUNCTIONS;

CONTROLLED DRUG DELIVERY;

CLATHRIN; CLAUDIN 1; CLAUDIN 2; CLAUDIN 3; CLAUDIN 4; CLAUDIN 5; OCCLUDIN; PEPTIDE C1C2; PEPTIDE C2C2; PEPTIDOMIMETIC AGENT; UNCLASSIFIED DRUG; TIGHT JUNCTION PROTEIN;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; CELL MEMBRANE; CELL MEMBRANE PERMEABILITY; CONTROLLED STUDY; CYTOSOL; ELECTRON MICROSCOPY; ENDOCYTOSIS; ENDOTHELIUM CELL; EPITHELIUM CELL; FREEZE FRACTURE; HUMAN; HUMAN CELL; INTERNALIZATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; TIGHT JUNCTION; CACO 2 CELL LINE; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY;

CACO-2 CELLS; CELL MEMBRANE PERMEABILITY; ENDOTHELIAL CELLS; EPITHELIAL CELLS; HEK293 CELLS; HUMANS; PEPTIDOMIMETICS; TIGHT JUNCTION PROTEINS; TIGHT JUNCTIONS;

EID: 84928038875     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.03.007     Document Type: Article

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