메뉴 건너뛰기




Volumn 15, Issue 1, 2015, Pages

Cancerous inhibitor of protein phosphatase 2A (CIP2A) is an independent prognostic marker in wild-type KRAS metastatic colorectal cancer after colorectal liver metastasectomy

Author keywords

CIP2A; Colorectal neoplasm; KRAS; Liver; Metastasectomy

Indexed keywords

AUTOANTIGEN; KIAA1524 PROTEIN, HUMAN; KRAS PROTEIN, HUMAN; MEMBRANE PROTEIN; ONCOPROTEIN; PROTEIN P21; RAS PROTEIN; TUMOR MARKER;

EID: 84928037856     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1300-3     Document Type: Article
Times cited : (17)

References (39)
  • 1
    • 33644685360 scopus 로고    scopus 로고
    • Extending the frontiers of surgical therapy for hepatic colorectal metastases: is there a limit?
    • Khatri VP, Petrelli NJ, Belghiti J. Extending the frontiers of surgical therapy for hepatic colorectal metastases: is there a limit? J Clin Oncol. 2005;23:8490-9.
    • (2005) J Clin Oncol , vol.23 , pp. 8490-8499
    • Khatri, V.P.1    Petrelli, N.J.2    Belghiti, J.3
  • 2
    • 77951693545 scopus 로고    scopus 로고
    • Surgery for colorectal liver metastases
    • Primrose JN. Surgery for colorectal liver metastases. Br J Cancer. 2010;102:1313-8.
    • (2010) Br J Cancer , vol.102 , pp. 1313-1318
    • Primrose, J.N.1
  • 3
    • 27244450852 scopus 로고    scopus 로고
    • OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer
    • Poston GJ, Adam R, Alberts S, Curley S, Figueras J, Haller D, et al. OncoSurge: a strategy for improving resectability with curative intent in metastatic colorectal cancer. J Clin Oncol. 2005;23:7125-34.
    • (2005) J Clin Oncol , vol.23 , pp. 7125-7134
    • Poston, G.J.1    Adam, R.2    Alberts, S.3    Curley, S.4    Figueras, J.5    Haller, D.6
  • 4
    • 33846939792 scopus 로고    scopus 로고
    • Survival after hepatic resection in metastatic colorectal cancer: a population-based study
    • Cummings LC, Payes JD, Cooper GS. Survival after hepatic resection in metastatic colorectal cancer: a population-based study. Cancer. 2007;109:718-26.
    • (2007) Cancer , vol.109 , pp. 718-726
    • Cummings, L.C.1    Payes, J.D.2    Cooper, G.S.3
  • 5
    • 84863722109 scopus 로고    scopus 로고
    • BRAF mutation is a prognostic biomarker for colorectal liver metastasectomy
    • Teng HW, Huang YC, Lin JK, Chen WS, Lin TC, Jiang JK, et al. BRAF mutation is a prognostic biomarker for colorectal liver metastasectomy. J Surg Oncol. 2012;106:123-9.
    • (2012) J Surg Oncol , vol.106 , pp. 123-129
    • Teng, H.W.1    Huang, Y.C.2    Lin, J.K.3    Chen, W.S.4    Lin, T.C.5    Jiang, J.K.6
  • 11
    • 84871567858 scopus 로고    scopus 로고
    • CIP2A is a predictor of survival and a novel therapeutic target in bladder urothelial cell carcinoma
    • Xue Y, Wu G, Wang X, Zou X, Zhang G, Xiao R, et al. CIP2A is a predictor of survival and a novel therapeutic target in bladder urothelial cell carcinoma. Med Oncol. 2013;30:406.
    • (2013) Med Oncol , vol.30 , pp. 406
    • Xue, Y.1    Wu, G.2    Wang, X.3    Zou, X.4    Zhang, G.5    Xiao, R.6
  • 14
    • 84865727989 scopus 로고    scopus 로고
    • CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis
    • He H, Wu G, Li W, Cao Y, Liu Y. CIP2A is highly expressed in hepatocellular carcinoma and predicts poor prognosis. Diagn Mol Pathol. 2012;21:143-9.
    • (2012) Diagn Mol Pathol , vol.21 , pp. 143-149
    • He, H.1    Wu, G.2    Li, W.3    Cao, Y.4    Liu, Y.5
  • 15
    • 79952925941 scopus 로고    scopus 로고
    • CIP2A is over-expressed in acute myeloid leukaemia and associated with HL60 cells proliferation and differentiation
    • Wang J, Li W, Li L, Yu X, Jia J, Chen C. CIP2A is over-expressed in acute myeloid leukaemia and associated with HL60 cells proliferation and differentiation. Int J Lab Hematol. 2011;33:290-8.
    • (2011) Int J Lab Hematol , vol.33 , pp. 290-298
    • Wang, J.1    Li, W.2    Li, L.3    Yu, X.4    Jia, J.5    Chen, C.6
  • 16
    • 84864061682 scopus 로고    scopus 로고
    • CIP2A is overexpressed in esophageal squamous cell carcinoma
    • Qu W, Li W, Wei L, Xing L, Wang X, Yu J. CIP2A is overexpressed in esophageal squamous cell carcinoma. Med Oncol. 2012;29:113-8.
    • (2012) Med Oncol , vol.29 , pp. 113-118
    • Qu, W.1    Li, W.2    Wei, L.3    Xing, L.4    Wang, X.5    Yu, J.6
  • 17
    • 52449121851 scopus 로고    scopus 로고
    • CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells
    • Li W, Ge Z, Liu C, Liu Z, Bjorkholm M, Jia J, et al. CIP2A is overexpressed in gastric cancer and its depletion leads to impaired clonogenicity, senescence, or differentiation of tumor cells. Clin Cancer Res. 2008;14:3722-8.
    • (2008) Clin Cancer Res , vol.14 , pp. 3722-3728
    • Li, W.1    Ge, Z.2    Liu, C.3    Liu, Z.4    Bjorkholm, M.5    Jia, J.6
  • 18
    • 85027932037 scopus 로고    scopus 로고
    • CIP2A is overexpressed in human ovarian cancer and regulates cell proliferation and apoptosis
    • Fang Y, Li Z, Wang X, Zhang S. CIP2A is overexpressed in human ovarian cancer and regulates cell proliferation and apoptosis. Tumour Biol. 2012;33:2299-306.
    • (2012) Tumour Biol , vol.33 , pp. 2299-2306
    • Fang, Y.1    Li, Z.2    Wang, X.3    Zhang, S.4
  • 19
    • 79955739210 scopus 로고    scopus 로고
    • CIP2A is Overexpressed in Non-Small Cell Lung Cancer and Correlates with Poor Prognosis
    • Dong QZ, Wang Y, Dong XJ, Li ZX, Tang ZP, Cui QZ, et al. CIP2A is Overexpressed in Non-Small Cell Lung Cancer and Correlates with Poor Prognosis. Ann Surg Oncol. 2010;18:857-65.
    • (2010) Ann Surg Oncol , vol.18 , pp. 857-865
    • Dong, Q.Z.1    Wang, Y.2    Dong, X.J.3    Li, Z.X.4    Tang, Z.P.5    Cui, Q.Z.6
  • 20
    • 84862790962 scopus 로고    scopus 로고
    • CIP2A-mediated Akt activation plays a role in bortezomib-induced apoptosis in head and neck squamous cell carcinoma cells
    • Lin YC, Chen KC, Chen CC, Cheng AL, Chen KF. CIP2A-mediated Akt activation plays a role in bortezomib-induced apoptosis in head and neck squamous cell carcinoma cells. Oral Oncol. 2012;48:585-93.
    • (2012) Oral Oncol , vol.48 , pp. 585-593
    • Lin, Y.C.1    Chen, K.C.2    Chen, C.C.3    Cheng, A.L.4    Chen, K.F.5
  • 21
    • 84874643751 scopus 로고    scopus 로고
    • Clinical implications of CIP2A protein expression in breast cancer
    • Yu G, Liu G, Dong J, Jin Y. Clinical implications of CIP2A protein expression in breast cancer. Med Oncol. 2013;30:524.
    • (2013) Med Oncol , vol.30 , pp. 524
    • Yu, G.1    Liu, G.2    Dong, J.3    Jin, Y.4
  • 24
    • 84866922110 scopus 로고    scopus 로고
    • Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity
    • Chen KF, Pao KC, Su JC, Chou YC, Liu CY, Chen HJ, et al. Development of erlotinib derivatives as CIP2A-ablating agents independent of EGFR activity. Bioorg Med Chem. 2012;20:6144-53.
    • (2012) Bioorg Med Chem , vol.20 , pp. 6144-6153
    • Chen, K.F.1    Pao, K.C.2    Su, J.C.3    Chou, Y.C.4    Liu, C.Y.5    Chen, H.J.6
  • 25
    • 80054760645 scopus 로고    scopus 로고
    • Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer
    • Park JH, Han SW, Oh DY, Im SA, Jeong SY, Park KJ, et al. Analysis of KRAS, BRAF, PTEN, IGF1R, EGFR intron 1 CA status in both primary tumors and paired metastases in determining benefit from cetuximab therapy in colon cancer. Cancer Chemother Pharmacol. 2011;68:1045-55.
    • (2011) Cancer Chemother Pharmacol , vol.68 , pp. 1045-1055
    • Park, J.H.1    Han, S.W.2    Oh, D.Y.3    Im, S.A.4    Jeong, S.Y.5    Park, K.J.6
  • 26
  • 27
    • 79956310674 scopus 로고    scopus 로고
    • Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study
    • Bokemeyer C, Bondarenko I, Hartmann JT, de Braud F, Schuch G, Zubel A, et al. Efficacy according to biomarker status of cetuximab plus FOLFOX-4 as first-line treatment for metastatic colorectal cancer: the OPUS study. Ann Oncol. 2011;22:1535-46.
    • (2011) Ann Oncol , vol.22 , pp. 1535-1546
    • Bokemeyer, C.1    Bondarenko, I.2    Hartmann, J.T.3    Braud, F.4    Schuch, G.5    Zubel, A.6
  • 29
    • 50349091081 scopus 로고    scopus 로고
    • Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer
    • French AJ, Sargent DJ, Burgart LJ, Foster NR, Kabat BF, Goldberg R, et al. Prognostic significance of defective mismatch repair and BRAF V600E in patients with colon cancer. Clin Cancer Res. 2008;14:3408-15.
    • (2008) Clin Cancer Res , vol.14 , pp. 3408-3415
    • French, A.J.1    Sargent, D.J.2    Burgart, L.J.3    Foster, N.R.4    Kabat, B.F.5    Goldberg, R.6
  • 30
    • 45549090492 scopus 로고    scopus 로고
    • Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability
    • Kakar S, Deng G, Sahai V, Matsuzaki K, Tanaka H, Miura S, et al. Clinicopathologic characteristics, CpG island methylator phenotype, and BRAF mutations in microsatellite-stable colorectal cancers without chromosomal instability. Arch Pathol Lab Med. 2008;132:958-64.
    • (2008) Arch Pathol Lab Med , vol.132 , pp. 958-964
    • Kakar, S.1    Deng, G.2    Sahai, V.3    Matsuzaki, K.4    Tanaka, H.5    Miura, S.6
  • 31
    • 58249089525 scopus 로고    scopus 로고
    • CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer
    • Ogino S, Nosho K, Kirkner GJ, Kawasaki T, Meyerhardt JA, Loda M, et al. CpG island methylator phenotype, microsatellite instability, BRAF mutation and clinical outcome in colon cancer. Gut. 2009;58:90-6.
    • (2009) Gut , vol.58 , pp. 90-96
    • Ogino, S.1    Nosho, K.2    Kirkner, G.J.3    Kawasaki, T.4    Meyerhardt, J.A.5    Loda, M.6
  • 32
    • 75749102647 scopus 로고    scopus 로고
    • Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial
    • Roth AD, Tejpar S, Delorenzi M, Yan P, Fiocca R, Klingbiel D, et al. Prognostic role of KRAS and BRAF in stage II and III resected colon cancer: results of the translational study on the PETACC-3, EORTC 40993, SAKK 60-00 trial. J Clin Oncol. 2010;28:466-74.
    • (2010) J Clin Oncol , vol.28 , pp. 466-474
    • Roth, A.D.1    Tejpar, S.2    Delorenzi, M.3    Yan, P.4    Fiocca, R.5    Klingbiel, D.6
  • 33
    • 79952282994 scopus 로고    scopus 로고
    • BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer
    • Yokota T, Ura T, Shibata N, Takahari D, Shitara K, Nomura M, et al. BRAF mutation is a powerful prognostic factor in advanced and recurrent colorectal cancer. Br J Cancer. 2011;104:856-62.
    • (2011) Br J Cancer , vol.104 , pp. 856-862
    • Yokota, T.1    Ura, T.2    Shibata, N.3    Takahari, D.4    Shitara, K.5    Nomura, M.6
  • 35
    • 67649652208 scopus 로고    scopus 로고
    • BRAF mutation in metastatic colorectal cancer
    • Tol J, Nagtegaal ID, Punt CJ. BRAF mutation in metastatic colorectal cancer. N Engl J Med. 2009;361:98-9.
    • (2009) N Engl J Med , vol.361 , pp. 98-99
    • Tol, J.1    Nagtegaal, I.D.2    Punt, C.J.3
  • 36
    • 84904958838 scopus 로고    scopus 로고
    • Zeng QL: [Expression of cancerous inhibitor of protein phosphatase 2A in tissue microarray of colorectal cancer and its clinical significance]
    • Peng XY, Chen W, Zhou K, Fu JP, Fu P. Zeng QL: [Expression of cancerous inhibitor of protein phosphatase 2A in tissue microarray of colorectal cancer and its clinical significance]. Zhonghua Wei Chang Wai Ke Za Zhi. 2013;16:1102-6.
    • (2013) Zhonghua Wei Chang Wai Ke Za Zhi , vol.16 , pp. 1102-1106
    • Peng, X.Y.1    Chen, W.2    Zhou, K.3    Fu, J.P.4    Fu, P.5
  • 37
    • 76649101395 scopus 로고    scopus 로고
    • Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERK pathways
    • Zhao D, Liu Z, Ding J, Li W, Sun Y, Yu H, et al. Helicobacter pylori CagA upregulation of CIP2A is dependent on the Src and MEK/ERK pathways. J Med Microbiol. 2010;59:259-65.
    • (2010) J Med Microbiol , vol.59 , pp. 259-265
    • Zhao, D.1    Liu, Z.2    Ding, J.3    Li, W.4    Sun, Y.5    Yu, H.6
  • 38
    • 79952916409 scopus 로고    scopus 로고
    • ETS1 mediates MEK1/2-dependent overexpression of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human cancer cells
    • Khanna A, Okkeri J, Bilgen T, Tiirikka T, Vihinen M, Visakorpi T, et al. ETS1 mediates MEK1/2-dependent overexpression of cancerous inhibitor of protein phosphatase 2A (CIP2A) in human cancer cells. PLoS One. 2011;6:e17979.
    • (2011) PLoS One , vol.6 , pp. e17979
    • Khanna, A.1    Okkeri, J.2    Bilgen, T.3    Tiirikka, T.4    Vihinen, M.5    Visakorpi, T.6
  • 39
    • 57449095367 scopus 로고    scopus 로고
    • Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer
    • Di Nicolantonio F, Martini M, Molinari F, Sartore-Bianchi A, Arena S, Saletti P, et al. Wild-type BRAF is required for response to panitumumab or cetuximab in metastatic colorectal cancer. J Clin Oncol. 2008;26:5705-12.
    • (2008) J Clin Oncol , vol.26 , pp. 5705-5712
    • Nicolantonio, F.1    Martini, M.2    Molinari, F.3    Sartore-Bianchi, A.4    Arena, S.5    Saletti, P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.