Validation of a sensitive and specific real-time PCR for detection and quantitation of hepatitis B virus covalently closed circular DNA in plasma of chronic hepatitis B patients

Journal of Medical Virology

Volumn 81, Issue 6, 2009, Pages 988-995

  Takkenberg, R B ^a,c   Zaaijer, H L ^a   Molenkamp, R ^a   Menting, S ^a   Terpstra, V ^a   Weegink, C J ^a   Dijkgraaf, M G W ^a   Jansen, P L M ^a   Reesink, H W ^a   Beld, M G H M ^b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ROYAL TROPICAL INSTITUTE   (Netherlands)

^c NONE   (Netherlands)

Author keywords

cccDNA; HBV; Plasma; Quantitation; Real time PCR

Indexed keywords

ALANINE AMINOTRANSFERASE; CIRCULAR DNA; HEPATITIS B(E) ANTIGEN; VIRUS DNA; HEPATITIS B SURFACE ANTIGEN;

ADULT; ARTICLE; BLOOD SAMPLING; CELL DEGENERATION; COMPARATIVE STUDY; CONTROLLED STUDY; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HISTOLOGY; HUMAN; HUMAN CELL; LIVER CELL; MAJOR CLINICAL STUDY; PLASMA; REAL TIME POLYMERASE CHAIN REACTION; SCORING SYSTEM; VALIDATION STUDY; BLOOD; EVALUATION; GENETICS; METHODOLOGY; MIDDLE AGED; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; VIROLOGY; VIRUS LOAD;

HEPATITIS B VIRUS;

ADULT; DNA, CIRCULAR; DNA, VIRAL; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; MIDDLE AGED; PLASMA; POLYMERASE CHAIN REACTION; SENSITIVITY AND SPECIFICITY; VIRAL LOAD;

EID: 66449095769     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.21477     Document Type: Article

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