메뉴 건너뛰기




Volumn 226, Issue , 2015, Pages 237-255

NK-1 antagonists and itch

Author keywords

Antagonist; Antinociception; G protein coupled receptor; Keratinocyte; Mast cell; Neurokinin 1 receptor; Neuropeptides; Prurigo; Pruritus; Sensory C fiber; Skin; Substance P; Tachykinins

Indexed keywords

APREPITANT; NEUROKININ 1 RECEPTOR; NEUROKININ 1 RECEPTOR ANTAGONIST; SUBSTANCE P; SUBSTANCE P ANTAGONIST; TACHYKININ; MORPHOLINE DERIVATIVE;

EID: 84928015854     PISSN: 01712004     EISSN: 18650325     Source Type: Book Series    
DOI: 10.1007/978-3-662-44605-8_14     Document Type: Article
Times cited : (49)

References (99)
  • 1
    • 0026649026 scopus 로고
    • Increased sensory neuropeptides in nodular prurigo: A quantitative immunohistochemical analysis
    • Abadía Molina F, Burrows NP, Jones RR, Terenghi G, Polak JM (1992) Increased sensory neuropeptides in nodular prurigo: a quantitative immunohistochemical analysis. Br J Dermatol 127: 344-351.
    • (1992) Br J Dermatol , vol.127 , pp. 344-351
    • Abadía Molina, F.1    Burrows, N.P.2    Jones, R.R.3    Terenghi, G.4    Polak, J.M.5
  • 5
    • 73249125645 scopus 로고    scopus 로고
    • Responses to intradermal injections of substance P in psoriasis patients with pruritus
    • Amatya B, Nordlind K, Wahlgren CF (2010) Responses to intradermal injections of substance P in psoriasis patients with pruritus. Skin Pharmacol Physiol 23: 133-138.
    • (2010) Skin Pharmacol Physiol , vol.23 , pp. 133-138
    • Amatya, B.1    Nordlind, K.2    Wahlgren, C.F.3
  • 6
    • 0037006368 scopus 로고    scopus 로고
    • Inhibitory effects of azelastine on substance P-induced itchassociated response in mice
    • Andoh T, Kuraishi Y (2002) Inhibitory effects of azelastine on substance P-induced itchassociated response in mice. Eur J Pharmacol 436: 235-239.
    • (2002) Eur J Pharmacol , vol.436 , pp. 235-239
    • Andoh, T.1    Kuraishi, Y.2
  • 7
    • 0032161858 scopus 로고    scopus 로고
    • Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice
    • Andoh T, Nagasawa T, Satoh M, Kuraishi Y (1998) Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J Pharmacol Exp Ther 286: 1140-1145.
    • (1998) J Pharmacol Exp Ther , vol.286 , pp. 1140-1145
    • Andoh, T.1    Nagasawa, T.2    Satoh, M.3    Kuraishi, Y.4
  • 8
    • 0035678082 scopus 로고    scopus 로고
    • Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice
    • Andoh T, Katsube N, Maruyama M, Kuraishi Y (2001) Involvement of leukotriene B(4) in substance P-induced itch-associated response in mice. J Invest Dermatol 117: 1621-1626.
    • (2001) J Invest Dermatol , vol.117 , pp. 1621-1626
    • Andoh, T.1    Katsube, N.2    Maruyama, M.3    Kuraishi, Y.4
  • 12
    • 0031018323 scopus 로고    scopus 로고
    • Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor
    • Böhm SK, Khitin LM, Smeekens SP, Grady EF, Payan DG, Bunnett NW (1997) Identification of potential tyrosine-containing endocytic motifs in the carboxyl-tail and seventh transmembrane domain of the neurokinin 1 receptor. J Biol Chem 272: 2363-2372.
    • (1997) J Biol Chem , vol.272 , pp. 2363-2372
    • Böhm, S.K.1    Khitin, L.M.2    Smeekens, S.P.3    Grady, E.F.4    Payan, D.G.5    Bunnett, N.W.6
  • 13
    • 79952407608 scopus 로고    scopus 로고
    • Oral aprepitant in the therapy of refractory pruritus in erythrodermic cutaneous T-cell lymphoma
    • Booken N, Heck M, Nicolay JP, Klemke CD, Goerdt S, Utikal J (2011) Oral aprepitant in the therapy of refractory pruritus in erythrodermic cutaneous T-cell lymphoma. Br J Dermatol 164: 665-667.
    • (2011) Br J Dermatol , vol.164 , pp. 665-667
    • Booken, N.1    Heck, M.2    Nicolay, J.P.3    Klemke, C.D.4    Goerdt, S.5    Utikal, J.6
  • 16
    • 76849108406 scopus 로고    scopus 로고
    • Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats
    • Carstens EE, Carstens MI, Simons CT, Jinks SL (2010) Dorsal horn neurons expressing NK-1 receptors mediate scratching in rats. Neuroreport 21: 303-308.
    • (2010) Neuroreport , vol.21 , pp. 303-308
    • Carstens, E.E.1    Carstens, M.I.2    Simons, C.T.3    Jinks, S.L.4
  • 17
    • 34447092362 scopus 로고    scopus 로고
    • Neuropeptides and their receptors in psoriatic skin in relation to pruritus
    • Chang SE, Han SS, Jung HJ, Choi JH (2007) Neuropeptides and their receptors in psoriatic skin in relation to pruritus. Br J Dermatol 156: 1272-1277.
    • (2007) Br J Dermatol , vol.156 , pp. 1272-1277
    • Chang, S.E.1    Han, S.S.2    Jung, H.J.3    Choi, J.H.4
  • 18
    • 1842790093 scopus 로고    scopus 로고
    • Aprepitant: A review of its use in the prevention of chemotherapyinduced nausea and vomiting
    • Dando TM, Perry C (2004) Aprepitant: a review of its use in the prevention of chemotherapyinduced nausea and vomiting. Drugs 64: 777-794.
    • (2004) Drugs , vol.64 , pp. 777-794
    • Dando, T.M.1    Perry, C.2
  • 20
    • 0034869022 scopus 로고    scopus 로고
    • Substance P: A new era, a new role
    • De Vane CL (2001) Substance P: a new era, a new role. Pharmacotherapy 21: 1061-1069.
    • (2001) Pharmacotherapy , vol.21 , pp. 1061-1069
    • De Vane, C.L.1
  • 21
    • 70349626195 scopus 로고    scopus 로고
    • Aprepitant as an antipruritic agent?
    • Duval A, Dubertret L (2009) Aprepitant as an antipruritic agent? N Engl J Med 361: 1415-1416.
    • (2009) N Engl J Med , vol.361 , pp. 1415-1416
    • Duval, A.1    Dubertret, L.2
  • 22
    • 79551570675 scopus 로고    scopus 로고
    • More on aprepitant for erlotinib-induced pruritus
    • Gerber PA, Buhren BA, Homey B (2011) More on aprepitant for erlotinib-induced pruritus. N Engl J Med 364: 486-487.
    • (2011) N Engl J Med , vol.364 , pp. 486-487
    • Gerber, P.A.1    Buhren, B.A.2    Homey, B.3
  • 23
    • 33750520115 scopus 로고    scopus 로고
    • Efficacy and safety of a neurokinin-1 receptor antagonist in postmenopausal women with overactive bladder with urge urinary incontinence
    • Green SA, Alon A, Ianus J, McNaughton KS, Tozzi CA, Reiss TF (2006) Efficacy and safety of a neurokinin-1 receptor antagonist in postmenopausal women with overactive bladder with urge urinary incontinence. J Urol 176: 2535-2540.
    • (2006) J Urol , vol.176 , pp. 2535-2540
    • Green, S.A.1    Alon, A.2    Ianus, J.3    McNaughton, K.S.4    Tozzi, C.A.5    Reiss, T.F.6
  • 24
    • 77953133224 scopus 로고    scopus 로고
    • Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis
    • Haas S, Capellino S, Phan NQ, Böhm M, Luger TA, Straub RH, Ständer S (2010) Low density of sympathetic nerve fibers relative to substance P-positive nerve fibers in lesional skin of chronic pruritus and prurigo nodularis. J Dermatol Sci 58: 193-197.
    • (2010) J Dermatol Sci , vol.58 , pp. 193-197
    • Haas, S.1    Capellino, S.2    Phan, N.Q.3    Böhm, M.4    Luger, T.A.5    Straub, R.H.6    Ständer, S.7
  • 25
    • 0018253625 scopus 로고
    • Flare and itch induced by substance P in human skin
    • Hägermark O, Hökfelt T, Pernow B (1978) Flare and itch induced by substance P in human skin. J Invest Dermatol 71: 233-235.
    • (1978) J Invest Dermatol , vol.71 , pp. 233-235
    • Hägermark, O.1    Hökfelt, T.2    Pernow, B.3
  • 27
    • 0347816226 scopus 로고    scopus 로고
    • The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapyinduced nausea and vomiting: A multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin-the Aprepitant Protocol 052 Study Group
    • Hesketh PJ, Grunberg SM, Gralla RJ, Warr DG, Roila F, de Wit R, Chawla SP, Carides AD, Ianus J, Elmer ME, Evans JK, Beck K, Reines S, Horgan KJ, Aprepitant Protocol 052 Study Group (2003) The oral neurokinin-1 antagonist aprepitant for the prevention of chemotherapyinduced nausea and vomiting: a multinational, randomized, double-blind, placebo-controlled trial in patients receiving high-dose cisplatin-the Aprepitant Protocol 052 Study Group. J Clin Oncol 21: 4077-4080.
    • (2003) J Clin Oncol , vol.21 , pp. 4077-4080
    • Hesketh, P.J.1    Grunberg, S.M.2    Gralla, R.J.3    Warr, D.G.4    Roila, F.5    de Wit, R.6    Chawla, S.P.7    Carides, A.D.8    Ianus, J.9    Elmer, M.E.10    Evans, J.K.11    Beck, K.12    Reines, S.13    Horgan, K.J.14
  • 28
    • 35348850974 scopus 로고    scopus 로고
    • Pathophysiology of nocturnal scratching in childhood atopic dermatitis: The role of brain-derived neurotrophic factor and substance P
    • Hon KL, Lam MC, Wong KY, Leung TF, Ng PC (2007) Pathophysiology of nocturnal scratching in childhood atopic dermatitis: the role of brain-derived neurotrophic factor and substance P. Br J Dermatol 157: 922-925.
    • (2007) Br J Dermatol , vol.157 , pp. 922-925
    • Hon, K.L.1    Lam, M.C.2    Wong, K.Y.3    Leung, T.F.4    Ng, P.C.5
  • 29
    • 63849235677 scopus 로고    scopus 로고
    • Severity scores, itch scores and plasma substance P levels in atopic dermatitis treated with standard topical therapy with oral olopatadine hydrochloride
    • Hosokawa C, Takeuchi S, Furue M (2009) Severity scores, itch scores and plasma substance P levels in atopic dermatitis treated with standard topical therapy with oral olopatadine hydrochloride. J Dermatol 36: 185-190.
    • (2009) J Dermatol , vol.36 , pp. 185-190
    • Hosokawa, C.1    Takeuchi, S.2    Furue, M.3
  • 33
    • 63849298539 scopus 로고    scopus 로고
    • Proinflammatory tachykinins that signal through the neurokinin 1 receptor promote survival of dendritic cells and potent cellular immunity
    • Janelsins BM, Mathers AR, Tkacheva OA, Erdos G, Shufesky WJ, Morelli AE, Larregina AT (2009) Proinflammatory tachykinins that signal through the neurokinin 1 receptor promote survival of dendritic cells and potent cellular immunity. Blood 113: 3017-3026.
    • (2009) Blood , vol.113 , pp. 3017-3026
    • Janelsins, B.M.1    Mathers, A.R.2    Tkacheva, O.A.3    Erdos, G.4    Shufesky, W.J.5    Morelli, A.E.6    Larregina, A.T.7
  • 35
    • 0037508908 scopus 로고    scopus 로고
    • Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema
    • Järvikallio A, Harvima IT, Naukkarinen A (2003) Mast cells, nerves and neuropeptides in atopic dermatitis and nummular eczema. Arch Dermatol Res 295: 2-7.
    • (2003) Arch Dermatol Res , vol.295 , pp. 2-7
    • Järvikallio, A.1    Harvima, I.T.2    Naukkarinen, A.3
  • 37
    • 0027360943 scopus 로고
    • Stimulation of the chemotactic migration of human fibroblasts by substance P
    • Kähler CM, Sitte BA, Reinisch N, Wiedermann CJ (1993) Stimulation of the chemotactic migration of human fibroblasts by substance P. Eur J Pharmacol 249: 281-286.
    • (1993) Eur J Pharmacol , vol.249 , pp. 281-286
    • Kähler, C.M.1    Sitte, B.A.2    Reinisch, N.3    Wiedermann, C.J.4
  • 38
    • 33644906608 scopus 로고    scopus 로고
    • Role of substance P in stress-derived degranulation of dermal mast cells in mice
    • Kawana S, Liang Z, Nagano M, Suzuki H (2006) Role of substance P in stress-derived degranulation of dermal mast cells in mice. J Dermatol Sci 42: 47-54.
    • (2006) J Dermatol Sci , vol.42 , pp. 47-54
    • Kawana, S.1    Liang, Z.2    Nagano, M.3    Suzuki, H.4
  • 42
    • 77950267997 scopus 로고    scopus 로고
    • Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: A Phase III, randomized, double-blind, placebo-controlled study
    • Kumagai H, Ebata T, Takamori K, Muramatsu T, Nakamoto H, Suzuki H (2010) Effect of a novel kappa-receptor agonist, nalfurafine hydrochloride, on severe itch in 337 haemodialysis patients: a Phase III, randomized, double-blind, placebo-controlled study. Nephrol Dial Transplant 25: 1251-1257.
    • (2010) Nephrol Dial Transplant , vol.25 , pp. 1251-1257
    • Kumagai, H.1    Ebata, T.2    Takamori, K.3    Muramatsu, T.4    Nakamoto, H.5    Suzuki, H.6
  • 43
    • 33646717773 scopus 로고    scopus 로고
    • Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation
    • Lai JP, Ho WZ, Kilpatrick LE, Wang X, Tuluc F, Korchak HM, Douglas SD (2006) Full-length and truncated neurokinin-1 receptor expression and function during monocyte/macrophage differentiation. Proc Natl Acad Sci USA 103: 7771-7776.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7771-7776
    • Lai, J.P.1    Ho, W.Z.2    Kilpatrick, L.E.3    Wang, X.4    Tuluc, F.5    Korchak, H.M.6    Douglas, S.D.7
  • 44
    • 64749113141 scopus 로고    scopus 로고
    • Pruritic and nociceptive sensations and dysesthesias from a spicule of cowhage
    • La Motte RH, Shimada SG, Green BG, Zelterman D (2009) Pruritic and nociceptive sensations and dysesthesias from a spicule of cowhage. J Neurophysiol 101: 1430-1443.
    • (2009) J Neurophysiol , vol.101 , pp. 1430-1443
    • La Motte, R.H.1    Shimada, S.G.2    Green, B.G.3    Zelterman, D.4
  • 45
    • 78651393548 scopus 로고    scopus 로고
    • Korean red ginseng extract ameliorates skin lesions in NC/Nga mice: An atopic dermatitis model
    • Lee JH, Cho SH (2011) Korean red ginseng extract ameliorates skin lesions in NC/Nga mice: an atopic dermatitis model. J Ethnopharmacol 133: 810-817.
    • (2011) J Ethnopharmacol , vol.133 , pp. 810-817
    • Lee, J.H.1    Cho, S.H.2
  • 46
    • 77958612727 scopus 로고    scopus 로고
    • Aprepitant for erlotinib-induced pruritus
    • Levêque D (2010) Aprepitant for erlotinib-induced pruritus. N Engl J Med 363: 1680-1681.
    • (2010) N Engl J Med , vol.363 , pp. 1680-1681
    • Levêque, D.1
  • 47
    • 84862777073 scopus 로고    scopus 로고
    • Substance P signaling controls mast cell activation, degranulation, and nociceptive sensitization in a rat fracture model of complex regional pain syndrome
    • Li WW, Guo TZ, Liang DY, Sun Y, Kingery WS, Clark JD (2012) Substance P signaling controls mast cell activation, degranulation, and nociceptive sensitization in a rat fracture model of complex regional pain syndrome. Anesthesiology 116: 882-95.
    • (2012) Anesthesiology , vol.116 , pp. 882-895
    • Li, W.W.1    Guo, T.Z.2    Liang, D.Y.3    Sun, Y.4    Kingery, W.S.5    Clark, J.D.6
  • 48
    • 84890441654 scopus 로고    scopus 로고
    • New insights into the mechanisms of itch: Are pain and itch controlled by distinct mechanisms?
    • Liu T, Ji RR (2013) New insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms? Pflugers Arch 465: 1671-1685.
    • (2013) Pflugers Arch , vol.465 , pp. 1671-1685
    • Liu, T.1    Ji, R.R.2
  • 49
    • 44649086391 scopus 로고    scopus 로고
    • Effect of cetirizine hydrochloride on the expression of substance P receptor and cytokines production in human epidermal keratinocytes and dermal fibroblasts
    • Liu JY, Zhao YZ, Peng C, Li FQ, Zhu QG, Hu JH (2008) Effect of cetirizine hydrochloride on the expression of substance P receptor and cytokines production in human epidermal keratinocytes and dermal fibroblasts. Yao Xue Xue Bao 43: 383-387.
    • (2008) Yao Xue Xue Bao , vol.43 , pp. 383-387
    • Liu, J.Y.1    Zhao, Y.Z.2    Peng, C.3    Li, F.Q.4    Zhu, Q.G.5    Hu, J.H.6
  • 52
    • 84866947538 scopus 로고    scopus 로고
    • Aprepitant for pruritus: Drug-drug interactions matter
    • Mir O, Coriat R (2012) Aprepitant for pruritus: drug-drug interactions matter. Lancet Oncol 13: 964-965.
    • (2012) Lancet Oncol , vol.13 , pp. 964-965
    • Mir, O.1    Coriat, R.2
  • 53
    • 79551506206 scopus 로고    scopus 로고
    • More on aprepitant for erlotinib-induced pruritus
    • Mir O, Blanchet B, Goldwasser F (2011) More on aprepitant for erlotinib-induced pruritus. N Engl J Med 364: 487.
    • (2011) N Engl J Med , vol.364
    • Mir, O.1    Blanchet, B.2    Goldwasser, F.3
  • 54
    • 77955151651 scopus 로고    scopus 로고
    • The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines
    • Muñoz M, Rosso M, Robles-Frias MJ, Salinas-Martín MV, Rosso R, González-Ortega A, Coveñas R (2010) The NK-1 receptor is expressed in human melanoma and is involved in the antitumor action of the NK-1 receptor antagonist aprepitant on melanoma cell lines. Lab Invest 90: 1259-1269.
    • (2010) Lab Invest , vol.90 , pp. 1259-1269
    • Muñoz, M.1    Rosso, M.2    Robles-Frias, M.J.3    Salinas-Martín, M.V.4    Rosso, R.5    González-Ortega, A.6    Coveñas, R.7
  • 55
    • 0242550855 scopus 로고    scopus 로고
    • Pruritogenic mediators in psoriasis vulgaris: Comparative evaluation of itch-associated cutaneous factors
    • Nakamura M, Toyoda M, Morohashi M (2003) Pruritogenic mediators in psoriasis vulgaris: comparative evaluation of itch-associated cutaneous factors. Br J Dermatol 149: 718-730.
    • (2003) Br J Dermatol , vol.149 , pp. 718-730
    • Nakamura, M.1    Toyoda, M.2    Morohashi, M.3
  • 56
  • 57
    • 2342634417 scopus 로고    scopus 로고
    • Involvement of substance P in scratching behaviour in an atopic dermatitis model
    • Ohmura T, Hayashi T, Satoh Y, Konomi A, Jung B, Satoh H (2004) Involvement of substance P in scratching behaviour in an atopic dermatitis model. Eur J Pharmacol 491: 191-194.
    • (2004) Eur J Pharmacol , vol.491 , pp. 191-194
    • Ohmura, T.1    Hayashi, T.2    Satoh, Y.3    Konomi, A.4    Jung, B.5    Satoh, H.6
  • 58
    • 84862535745 scopus 로고    scopus 로고
    • Structural features of the C-terminus from the human neurokinin-1 receptor
    • Orel M, Padros E, Manyosa J (2012) Structural features of the C-terminus from the human neurokinin-1 receptor. FEBS J 279(13): 2357-2367.
    • (2012) FEBS J , vol.279 , Issue.13 , pp. 2357-2367
    • Orel, M.1    Padros, E.2    Manyosa, J.3
  • 59
    • 0347915575 scopus 로고    scopus 로고
    • Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature
    • Patacchini R, Lecci A, Holzer P, Maggi CA (2004) Newly discovered tachykinins raise new questions about their peripheral roles and the tachykinin nomenclature. Trends Pharmacol Sci 25: 1-3.
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 1-3
    • Patacchini, R.1    Lecci, A.2    Holzer, P.3    Maggi, C.A.4
  • 60
    • 38149013922 scopus 로고    scopus 로고
    • Further exploring the brain-skin connection: Stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice
    • Pavlovic S, Daniltchenko M, Tobin DJ, Hagen E, Hunt SP, Klapp BF, Arck PC, Peters EM (2008) Further exploring the brain-skin connection: stress worsens dermatitis via substance P-dependent neurogenic inflammation in mice. J Invest Dermatol 128: 434-446.
    • (2008) J Invest Dermatol , vol.128 , pp. 434-446
    • Pavlovic, S.1    Daniltchenko, M.2    Tobin, D.J.3    Hagen, E.4    Hunt, S.P.5    Klapp, B.F.6    Arck, P.C.7    Peters, E.M.8
  • 61
    • 38349078214 scopus 로고    scopus 로고
    • Probing the effects of stress mediators on the human hair follicle: Substance P holds central position
    • Peters EM, Liotiri S, Bodo E, Hagen E, Bíro T, Arck PC, Paus R (2007) Probing the effects of stress mediators on the human hair follicle: substance P holds central position. Am J Pathol 171: 1872-1886.
    • (2007) Am J Pathol , vol.171 , pp. 1872-1886
    • Peters, E.M.1    Liotiri, S.2    Bodo, E.3    Hagen, E.4    Bíro, T.5    Arck, P.C.6    Paus, R.7
  • 62
    • 84867746154 scopus 로고    scopus 로고
    • Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells
    • Ping F, Shang J, Zhou J, Song J, Zhang L (2012) Activation of neurokinin-1 receptor by substance P inhibits melanogenesis in B16-F10 melanoma cells. Int J Biochem Cell Biol 44: 2342-2348.
    • (2012) Int J Biochem Cell Biol , vol.44 , pp. 2342-2348
    • Ping, F.1    Shang, J.2    Zhou, J.3    Song, J.4    Zhang, L.5
  • 65
    • 34247639048 scopus 로고    scopus 로고
    • Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus
    • Remröd C, Lonne-Rahm S, Nordlind K (2007) Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus. Arch Dermatol Res 299: 85-91.
    • (2007) Arch Dermatol Res , vol.299 , pp. 85-91
    • Remröd, C.1    Lonne-Rahm, S.2    Nordlind, K.3
  • 66
    • 79955423394 scopus 로고    scopus 로고
    • Safety evaluation of aprepitant for the prevention of chemotherapy-induced nausea and vomiting
    • Ruhlmann CH, Herrstedt J (2011) Safety evaluation of aprepitant for the prevention of chemotherapy-induced nausea and vomiting. Expert Opin Drug Saf 10: 449-462.
    • (2011) Expert Opin Drug Saf , vol.10 , pp. 449-462
    • Ruhlmann, C.H.1    Herrstedt, J.2
  • 67
    • 84875865528 scopus 로고    scopus 로고
    • De novo expression of neurokinin-1 receptors by spinoparabrachial lamina I pyramidal neurons following a peripheral nerve lesion
    • Saeed AW, Ribeiro-da-Silva A (2013) De novo expression of neurokinin-1 receptors by spinoparabrachial lamina I pyramidal neurons following a peripheral nerve lesion. J Comp Neurol 521: 1915-1928.
    • (2013) J Comp Neurol , vol.521 , pp. 1915-1928
    • Saeed, A.W.1    Ribeiro-da-Silva, A.2
  • 68
    • 69649089496 scopus 로고    scopus 로고
    • Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision
    • Sahbaie P, Shi X, Guo TZ, Qiao Y, Yeomans DC, Kingery WS, Clark JD (2009) Role of substance P signaling in enhanced nociceptive sensitization and local cytokine production after incision. Pain 145: 341-349.
    • (2009) Pain , vol.145 , pp. 341-349
    • Sahbaie, P.1    Shi, X.2    Guo, T.Z.3    Qiao, Y.4    Yeomans, D.C.5    Kingery, W.S.6    Clark, J.D.7
  • 69
    • 38349009084 scopus 로고    scopus 로고
    • The role of selected neuropeptides in pathogenesis of atopic dermatitis
    • Salomon J, Baran E (2008) The role of selected neuropeptides in pathogenesis of atopic dermatitis. J Eur Acad Dermatol Veneoreol 22: 223-228.
    • (2008) J Eur Acad Dermatol Veneoreol , vol.22 , pp. 223-228
    • Salomon, J.1    Baran, E.2
  • 72
    • 0346665747 scopus 로고    scopus 로고
    • Modulation of cutaneous inflammation by angiotensin-converting enzyme
    • Scholzen TE, Ständer S, Riemann H, Brzoska T, Luger TA (2003) Modulation of cutaneous inflammation by angiotensin-converting enzyme. J Immunol 170: 3866-3873.
    • (2003) J Immunol , vol.170 , pp. 3866-3873
    • Scholzen, T.E.1    Ständer, S.2    Riemann, H.3    Brzoska, T.4    Luger, T.A.5
  • 73
    • 6944223139 scopus 로고    scopus 로고
    • Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage
    • Scholzen TE, Steinhoff M, Sindrilaru A, Schwarz A, Bunnett NW, Luger TA, Armstrong CA, Ansel JC (2004) Cutaneous allergic contact dermatitis responses are diminished in mice deficient in neurokinin 1 receptors and augmented by neurokinin 2 receptor blockage. FASEB J 18: 1007-1009.
    • (2004) FASEB J , vol.18 , pp. 1007-1009
    • Scholzen, T.E.1    Steinhoff, M.2    Sindrilaru, A.3    Schwarz, A.4    Bunnett, N.W.5    Luger, T.A.6    Armstrong, C.A.7    Ansel, J.C.8
  • 74
    • 2442598980 scopus 로고    scopus 로고
    • Two types of C nociceptors in human skin and their behavior in areas of capsaicin-induced secondary hyperalgesia
    • Serra J, Campero M, Bostock H, Ochoa J (2004) Two types of C nociceptors in human skin and their behavior in areas of capsaicin-induced secondary hyperalgesia. J Neurophysiol 91: 2770-2781.
    • (2004) J Neurophysiol , vol.91 , pp. 2770-2781
    • Serra, J.1    Campero, M.2    Bostock, H.3    Ochoa, J.4
  • 76
    • 84858442431 scopus 로고    scopus 로고
    • Evaluation of the German guideline for chronic pruritus: Results of a retrospective study on 385 patients
    • Siepmann D, Weishaupt C, Luger TA, Ständer S (2011) Evaluation of the German guideline for chronic pruritus: results of a retrospective study on 385 patients. Dermatology 223: 374-380.
    • (2011) Dermatology , vol.223 , pp. 374-380
    • Siepmann, D.1    Weishaupt, C.2    Luger, T.A.3    Ständer, S.4
  • 77
    • 0032856498 scopus 로고    scopus 로고
    • Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P: A link to neurogenic skin disorders
    • Singh LK, Pang X, Alexacos N, Letourneau R, Theoharides TC (1999) Acute immobilization stress triggers skin mast cell degranulation via corticotropin releasing hormone, neurotensin, and substance P: a link to neurogenic skin disorders. Brain Behav Immun 13: 225-239.
    • (1999) Brain Behav Immun , vol.13 , pp. 225-239
    • Singh, L.K.1    Pang, X.2    Alexacos, N.3    Letourneau, R.4    Theoharides, T.C.5
  • 78
    • 17444438461 scopus 로고    scopus 로고
    • Quantitation of neurokinin 1 receptor internalization and recycling in guinea-pig myenteric neurons
    • Southwell BR, Seybold VS, Woodman HL, Jenkinson KM, Furness JB (1998) Quantitation of neurokinin 1 receptor internalization and recycling in guinea-pig myenteric neurons. Neuroscience 87: 925-931.
    • (1998) Neuroscience , vol.87 , pp. 925-931
    • Southwell, B.R.1    Seybold, V.S.2    Woodman, H.L.3    Jenkinson, K.M.4    Furness, J.B.5
  • 81
    • 77953136244 scopus 로고    scopus 로고
    • Targeting the neurokinin receptor 1 as a new antipruritic strategy: Results of a case series with aprepitant
    • Ständer S, Siepmann D, Luger TA (2009) Targeting the neurokinin receptor 1 as a new antipruritic strategy: results of a case series with aprepitant. Acta Derm Venereol 89: 717.
    • (2009) Acta Derm Venereol , vol.89
    • Ständer, S.1    Siepmann, D.2    Luger, T.A.3
  • 82
  • 85
    • 84863458288 scopus 로고    scopus 로고
    • Suppression of neurokinin-1 receptor in trigeminal ganglia attenuates central sensitization following inflammation
    • Takeda M, Takahashi M, Matsumoto S (2012) Suppression of neurokinin-1 receptor in trigeminal ganglia attenuates central sensitization following inflammation. J Peripher Nerv Syst 17: 169-181.
    • (2012) J Peripher Nerv Syst , vol.17 , pp. 169-181
    • Takeda, M.1    Takahashi, M.2    Matsumoto, S.3
  • 86
    • 0023866539 scopus 로고
    • Effects of substance P and substance K on the growth of cultured keratinocytes
    • Tanaka T, Danno K, Ikai K, Imamura S (1988) Effects of substance P and substance K on the growth of cultured keratinocytes. J Invest Dermatol 90: 399-401.
    • (1988) J Invest Dermatol , vol.90 , pp. 399-401
    • Tanaka, T.1    Danno, K.2    Ikai, K.3    Imamura, S.4
  • 87
    • 80052541730 scopus 로고    scopus 로고
    • A randomized, placebo controlled, double masked phase IB study evaluating the safety and antiviral activity of aprepitant, a neurokinin-1 receptor antagonist in HIV-1 infected adults
    • Tebas P, Tuluc F, Barrett JS, Wagner W, Kim D, Zhao H, Gonin R, Korelitz J, Douglas SD (2011) A randomized, placebo controlled, double masked phase IB study evaluating the safety and antiviral activity of aprepitant, a neurokinin-1 receptor antagonist in HIV-1 infected adults. PLoS One 6: e24180.
    • (2011) PLoS One , vol.6
    • Tebas, P.1    Tuluc, F.2    Barrett, J.S.3    Wagner, W.4    Kim, D.5    Zhao, H.6    Gonin, R.7    Korelitz, J.8    Douglas, S.D.9
  • 88
    • 84878380808 scopus 로고    scopus 로고
    • Peripheral substance P and neurokinin-1 receptors have a role in inflammatory and neuropathic orofacial pain models
    • Teodoro FC, Tronco Júnior MF, Zampronio AR, Martini AC, Rae GA, Chichorro JG (2013) Peripheral substance P and neurokinin-1 receptors have a role in inflammatory and neuropathic orofacial pain models. Neuropeptides 47: 199-206.
    • (2013) Neuropeptides , vol.47 , pp. 199-206
    • Teodoro, F.C.1    Tronco, M.F.2    Zampronio, A.R.3    Martini, A.C.4    Rae, G.A.5    Chichorro, J.G.6
  • 89
    • 0036108887 scopus 로고    scopus 로고
    • Experimental itch in sodium lauryl sulphate-inflamed and normal skin in humans: A randomized, double-blind, placebo-controlled study of histamine and other inducers of itch
    • Thomsen JS, Sonne M, Benfeldt E, Jensen SB, Serup J, Menné T (2002) Experimental itch in sodium lauryl sulphate-inflamed and normal skin in humans: a randomized, double-blind, placebo-controlled study of histamine and other inducers of itch. Br J Dermatol 146: 792-800.
    • (2002) Br J Dermatol , vol.146 , pp. 792-800
    • Thomsen, J.S.1    Sonne, M.2    Benfeldt, E.3    Jensen, S.B.4    Serup, J.5    Menné, T.6
  • 90
    • 83655192773 scopus 로고    scopus 로고
    • Aprepitant: Evidence of its effectiveness in patients with refractory pruritus continues
    • Torres T, Fernandes I, Selores M, Alves R, Lima M (2012) Aprepitant: evidence of its effectiveness in patients with refractory pruritus continues. J Am Acad Dermatol 66: e14-e15.
    • (2012) J Am Acad Dermatol , vol.66 , pp. e14-e15
    • Torres, T.1    Fernandes, I.2    Selores, M.3    Alves, R.4    Lima, M.5
  • 91
    • 0036063881 scopus 로고    scopus 로고
    • Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis
    • Toyoda M, Nakamura M, Makino T, Hino T, Kagoura M, Morohashi M (2002) Nerve growth factor and substance P are useful plasma markers of disease activity in atopic dermatitis. Br J Dermatol 147: 71-79.
    • (2002) Br J Dermatol , vol.147 , pp. 71-79
    • Toyoda, M.1    Nakamura, M.2    Makino, T.3    Hino, T.4    Kagoura, M.5    Morohashi, M.6
  • 92
    • 77956624273 scopus 로고    scopus 로고
    • Serum concentrations of substance P in cholestasis
    • Trivedi M, Bergasa NV (2010) Serum concentrations of substance P in cholestasis. Ann Hepatol 9: 177-180.
    • (2010) Ann Hepatol , vol.9 , pp. 177-180
    • Trivedi, M.1    Bergasa, N.V.2
  • 94
    • 77954832203 scopus 로고    scopus 로고
    • Aprepitant for erlotinib-induced pruritus
    • Vincenzi B, Tonini G, Santini D (2010b) Aprepitant for erlotinib-induced pruritus. N Engl J Med 363: 397-398.
    • (2010) N Engl J Med , vol.363 , pp. 397-398
    • Vincenzi, B.1    Tonini, G.2    Santini, D.3
  • 96
    • 69249090603 scopus 로고    scopus 로고
    • Epidemiology of itch: Adding to the burden of skin morbidity
    • Weisshaar E, Dalgard F (2009) Epidemiology of itch: adding to the burden of skin morbidity. Acta Derm Venereol 89: 339-350.
    • (2009) Acta Derm Venereol , vol.89 , pp. 339-350
    • Weisshaar, E.1    Dalgard, F.2
  • 98
    • 79956049040 scopus 로고    scopus 로고
    • Altered thermal hyperaemia in human skin by prior desensitization of neurokinin-1 receptors
    • Wong BJ, Minson CT (2011) Altered thermal hyperaemia in human skin by prior desensitization of neurokinin-1 receptors. Exp Physiol 96: 599-609.
    • (2011) Exp Physiol , vol.96 , pp. 599-609
    • Wong, B.J.1    Minson, C.T.2
  • 99
    • 34548511354 scopus 로고    scopus 로고
    • Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice
    • Yamaoka J, Kawana S (2007) Rapid changes in substance P signaling and neutral endopeptidase induced by skin-scratching stimulation in mice. J Dermatol Sci 48: 123-32.
    • (2007) J Dermatol Sci , vol.48 , pp. 123-132
    • Yamaoka, J.1    Kawana, S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.