Responses to intradermal injections of substance P in psoriasis patients with pruritus

Skin Pharmacology and Physiology

Volumn 23, Issue 3, 2010, Pages 133-138

  Amatya, B ^a   Nordlind, K ^a   Wahlgren, C F ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Histamine; Intradermal injection; Itch; Pruritogenic mediators; Psoriasis; Substance P

Indexed keywords

HISTAMINE; SODIUM CHLORIDE; SUBSTANCE P;

ADULT; AREA UNDER THE CURVE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLARE; HUMAN; INTRADERMAL DRUG ADMINISTRATION; LATENT PERIOD; MALE; PATHOGENESIS; PERCEPTION; PRIORITY JOURNAL; PRURITUS; PSORIASIS; SKIN DEFECT; SKIN MANIFESTATION; TIME PERCEPTION; URTICARIA;

ADULT; AREA UNDER CURVE; CASE-CONTROL STUDIES; DOUBLE-BLIND METHOD; FEMALE; HISTAMINE; HUMANS; INJECTIONS, INTRADERMAL; MALE; MIDDLE AGED; PRURITUS; PSORIASIS; SEVERITY OF ILLNESS INDEX; SUBSTANCE P; TIME FACTORS;

EID: 73249125645     PISSN: 16605527     EISSN: None     Source Type: Journal    
DOI: 10.1159/000270385     Document Type: Article

References (29)

1. Reich A, Orda A, Wisnicka B, Szepietowski JC: Plasma neuropeptides and perception of pruritus in psoriasis. Acta Derm Venereol 2007; 87: 299-304.
2. Nakamura M, Toyoda M, Morohashi M: Pruritogenic mediators in psoriasis vulgaris: comparative evaluation of itch-associated cutaneous factors. Br J Dermatol 2003; 149: 718-730.
3. Hundley JL, Yosipovitch G: Mirtazapine for reducing nocturnal itch in patients with chronic pruritus: a pilot study. J Am Acad Dermatol 2004; 50: 889-891.
4. Reich A, Szepietowski JC: Mediators of pruritus in psoriasis. Mediators Inflamm 2007; 2007: 64727.
5. Hägermark O, Hökfelt T, Pernow B: Flare and itch induced by substance P in human skin. J Invest Dermatol 1978; 71: 233-235.
6. Marsella R, Nicklin CF: Intradermal skin test reactivity to histamine and substance P is blunted in dogs with atopic dermatitis. Vet Dermatol 2001; 12: 149-154.
7. Andoh T, Katsube N, Maruyama M, Kuraishi Y: Involvement of leukotriene B 4 in substance P-induced itch-associated response in mice. J Invest Dermatol 2001; 117: 1621-1626.
8. Coulson IH, Holden CA: Cutaneous reactions to substance P and histamine in atopic dermatitis. Br J Dermatol 1990; 122: 343-349.
9. Heyer G, Hornstein OP, Handwerker HO: Reactions to intradermally injected substance P and topically applied mustard oil in atopic dermatitis patients. Acta Derm Venereol 1991; 71: 291-295.
10. Fredriksson T, Pettersson U: Severe psoriasis: oral therapy with a new retinoid. Dermatologica 1978; 157: 238-244.
11. Wahlgren CF: Measurement of itch. Semin Dermatol 1995; 14: 277-284.
12. Wahlgren CF, Ekblom A, Hagermark O: Some aspects of the experimental induction and measurement of itch. Acta Derm Venereol 1989; 69: 185-189.
13. Wahlgren CF, Ekblom A: Perception of histamine- induced itch elicited in three different skin regions. Acta Derm Venereol 1991; 71: 205-208.
14. Wahlgren CF, Tengvall Linder M, Hägermark Ö, Scheynius A: Itch and inflammation induced by intradermally injected interleukin-2 in atopic dermatitis patients and healthy subjects. Arch Dermatol Res 1995; 287: 572-580.
15. Dreborg S: Skin tests used in type I allergy testing: position paper. 2. Methods for skin testing. Allergy 1989; 44: 22-30.
16. Giannetti A, Girolomoni G: Skin reactivity to neuropeptides in atopic dermatitis. Br J Dermatol 1989; 121: 681-688.
17. Thomsen JS, Sonne M, Benfeldt E, Jensen SB, Serup J, Menne T: Experimental itch in sodium lauryl sulphate-inflamed and normal skin in humans: a randomized, doubleblind, placebo-controlled study of histamine and other inducers of itch. Br J Dermatol 2002; 146: 792-800.
18. Heyer G: Abnormal cutaneous neurosensitivity in atopic skin. Acta Derm Venereol Suppl (Stockh) 1992; 176: 93-94.
19. Salomon J, Baran E: The role of selected neuropeptides in pathogenesis of atopic dermatitis. J Eur Acad Dermatol Venereol 2008; 22: 223-228.
20. Reich A, Orda A, Wisnicka B, Szepietowski JC: Plasma concentration of selected neuropeptides in patients suffering from psoriasis. Exp Dermatol 2007; 16: 421-428.
21. Saraceno R, Kleyn CE, Terenghi G, Griffiths CE: The role of neuropeptides in psoriasis. Br J Dermatol 2006; 155: 876-882.
22. Remröd C, Lonne-Rahm S, Nordlind K: Study of substance P and its receptor neurokinin-1 in psoriasis and their relation to chronic stress and pruritus. Arch Dermatol Res 2007; 299: 85-91.
23. Heyer G, Hornstein OP, Handwerker HO: Skin reactions and itch sensation induced by epicutaneous histamine application in atopic dermatitis and controls. J Invest Dermatol 1989; 93: 492-496.
24. Uehara M: Reduced histamine reaction in atopic dermatitis. Arch Dermatol 1982; 118: 244-245.
25. Krogstad AL, Lönnroth P, Larson G, Wallin BG: Increased interstitial histamine concentration in the psoriatic plaque. J Invest Dermatol 1997; 109: 632-635.
26. Yosipovitch G, Goon A, Wee J, Chan YH, Goh CL: The prevalence and clinical characteristics of pruritus among patients with extensive psoriasis. Br J Dermatol 2000; 143: 969-973.
27. Szepietowski JC, Reich A, Wisnicka B: Itching in patients suffering from psoriasis. Acta Dermatovenerol Croat 2002; 10: 221-226.
28. Amatya B, Wennersten G, Nordlind K: Patients' perspective of pruritus in chronic plaque psoriasis: a questionnaire-based study. J Eur Acad Dermatol Venereol 2008; 22: 822-826.
29. Sampogna F, Gisondi P, Melchi CF, Amerio P, Girolomoni G, Abeni D: Prevalence of symptoms experienced by patients with different clinical types of psoriasis. Br J Dermatol 2004; 151: 594-599.