A single dose biodegradable vaccine depot that induces persistently high levels of antibody over a year

Biomaterials

Volumn 53, Issue , 2015, Pages 50-57

  Chua, Brendon Y ^a   Sekiya, Toshiki ^a   Al Kobaisi, Mohammad ^b   Short, Kirsty R ^a   Mainwaring, David E ^b   Jackson, David C ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b SWINBURNE UNIVERSITY OF TECHNOLOGY   (Australia)

Author keywords

Antibody; Chitosan; Depot; Hydroxyapatite; Single dose; Vaccine

Indexed keywords

ALUMINUM HYDROXIDE; ANTIBODIES; ANTIGENS; CHITOSAN; CROSSLINKING; EMULSIFICATION; HYDROXYAPATITE; MAMMALS; SULFUR COMPOUNDS;

ALUMINIUM HYDROXIDE; ANTIBODY RESPONSE; CHONDROITIN SULPHATE; CROSS LINKING AGENTS; DEPOT; PLATFORM TECHNOLOGY; SINGLE-DOSE; WHOLE-BODY IMAGING;

VACCINES;

ALUMINUM HYDROXIDE; ANTIBODY; CHITOSAN; CHONDROITIN SULFATE; FREUND ADJUVANT; HYDROXYAPATITE; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2A ANTIBODY; IMMUNOGLOBULIN G2B ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; OVALBUMIN; QUIL A; TRIPOLYPHOSPHATE; UNCLASSIFIED DRUG; VACCINE; BIOMATERIAL; DELAYED RELEASE FORMULATION;

ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIBODY TITER; ARTICLE; ELECTRON MICROSCOPY; EMULSION; ENZYME LINKED IMMUNOSORBENT ASSAY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SINGLE DRUG DOSE; VACCINATION; WHOLE BODY IMAGING; ANIMAL; ANTIBODY PRODUCTION; BAGG ALBINO MOUSE; DELAYED RELEASE FORMULATION; IMMUNOLOGY;

ANIMALIA; MUS;

ANIMALS; ANTIBODY FORMATION; BIOCOMPATIBLE MATERIALS; DELAYED-ACTION PREPARATIONS; MALE; MICE; MICE, INBRED BALB C; VACCINES;

EID: 84927945389     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2015.02.066     Document Type: Article

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