Human macrophage activation triggered by chitotriosidase-mediated chitin and chitosan degradation

Biomaterials

Volumn 31, Issue 33, 2010, Pages 8556-8563

  Gorzelanny, Christian ^a,b   Pöppelmann, Birgit ^b   Pappelbaum, Karin ^b   Moerschbacher, Bruno M ^b   Schneider, Stefan W ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Biocompatibility; Chitin Chitosan; Inflammation; Innate immunity; Mammalian chitinase

Indexed keywords

CELL WALLS; CHITIN/CHITOSAN; CHITINASES; CHITOSAN OLIGOMER; COOPERATIVITY; CRYPTOCOCCUS NEOFORMANS; DEACETYLATION; GLUCOSAMINES; HUMAN MACROPHAGE ACTIVATION; HUMAN MACROPHAGES; HUMAN PATHOGENS; IMMUNOLOGICAL PROPERTIES; INFLAMMATION; INFLAMMATORY CYTOKINES; INFLAMMATORY PROPERTIES; INFLAMMATORY RESPONSE; INNATE IMMUNITY; MEDICAL DEVICES; METABOLIC FATE; PATHOGENIC FUNGI; PROCESSIVITY; STRUCTURAL COMPONENT; WOUND DRESSINGS;

ACETYLATION; BIOCOMPATIBILITY; BIOMEDICAL ENGINEERING; CHEMICAL ACTIVATION; CHITOSAN; DEGRADATION; FUNGI; MACROPHAGES; MAMMALS; OLIGOMERS; PATHOLOGY;

CHITIN;

CHITIN; CHITINASE; CHITOSAN; CHITOTRIOSIDASE; CYTOKINE; INTERLEUKIN 6; INTERLEUKIN 8; OLIGOMER; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; BIOCOMPATIBILITY; COMPUTER PROGRAM; CONTROLLED STUDY; CRYPTOCOCCUS NEOFORMANS; ENZYME ACTIVITY; FUNGUS; HUMAN; HUMAN CELL; INFLAMMATION; INNATE IMMUNITY; MACROPHAGE ACTIVATION; MASS SPECTROMETRY; MONOCYTE; NEMATODE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; POLYMERIZATION; PRIORITY JOURNAL; PROTEIN DEGRADATION;

CELL LINE; CHITIN; CHITOSAN; COMPUTATIONAL BIOLOGY; HEXOSAMINIDASES; HUMANS; INFLAMMATION; MACROPHAGE ACTIVATION; MACROPHAGES; MODELS, BIOLOGICAL;

FILOBASIDIELLA NEOFORMANS; FUNGI; MAMMALIA; NEMATODA;

EID: 77957310151     PISSN: 01429612     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2010.07.100     Document Type: Article

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