Low blood folates in NTD pregnancies are only partly explained by thermolabile 5,10-methylenetetrahydrofolate reductase: Low folate status alone may be the critical factor

American Journal of Medical Genetics

Volumn 78, Issue 2, 1998, Pages 155-159

  Molloy, Anne M ^a   Mills, James L ^b   Kirke, Peadar N ^c   Ramsbottom, Dorothy ^a   McPartlin, Joseph M ^a   Burke, Helen ^c   Conley, Mary ^b   Whitehead, Alexander S ^a   Weir, Donald G ^a   Scott, John M ^a  

^a TRINITY COLLEGE DUBLIN   (Ireland)

^b EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH AND HUMAN DEVELOPMENT   (United States)

^c HEALTH RESEARCH BOARD   (Ireland)

Author keywords

5,10 methylenetetrahydrofolate reductase; Homocysteine; Neural tube defects; Plasma folate; Red cell folates; Vitamin B12

Indexed keywords

FOLIC ACID; METHYLENETETRAHYDROFOLIC ACID;

ARTICLE; CONTROLLED STUDY; FOLIC ACID BLOOD LEVEL; FOOD INTAKE; GENETIC SCREENING; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NEURAL TUBE DEFECT; PRIORITY JOURNAL; RISK ASSESSMENT;

5,10-METHYLENETETRAHYDROFOLATE REDUCTASE (FADH2); CASE-CONTROL STUDIES; CYSTEINE; FEMALE; FOLIC ACID; GENOTYPE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); NEURAL TUBE DEFECTS; OXIDOREDUCTASES; PREGNANCY; PREGNANCY COMPLICATIONS; THREONINE;

EID: 0032581051     PISSN: 01487299     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1096-8628(19980630)78:2<155::AID-AJMG11>3.0.CO;2-M     Document Type: Article

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