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Volumn 27, Issue 6, 2014, Pages 493-500

Optimizing azole antifungal therapy in the prophylaxis and treatment of fungal infections

Author keywords

Azole antifungal agents; Dose individualization; Exposure response; Therapeutic drug monitoring

Indexed keywords

ISAVUCONAZOLE; ITRACONAZOLE; POSACONAZOLE; PYRROLE DERIVATIVE; VORICONAZOLE; ANTIFUNGAL AGENT; TRIAZOLE DERIVATIVE;

EID: 84927796421     PISSN: 09517375     EISSN: 14736527     Source Type: Journal    
DOI: 10.1097/QCO.0000000000000103     Document Type: Review
Times cited : (24)

References (116)
  • 1
    • 1642335814 scopus 로고    scopus 로고
    • History of the development of azole derivatives
    • Maertens JA. History of the development of azole derivatives. Clin Microbiol Infect 2004; 10 (Suppl 1):1-10.
    • (2004) Clin Microbiol Infect , vol.10 , pp. 1-10
    • Maertens, J.A.1
  • 2
    • 0033796814 scopus 로고    scopus 로고
    • Introduction to antifungal drugs
    • Dismukes WE. Introduction to antifungal drugs. Clin Infect Dis 2000; 30:653-657.
    • (2000) Clin Infect Dis , vol.30 , pp. 653-657
    • Dismukes, W.E.1
  • 3
    • 84868033749 scopus 로고    scopus 로고
    • Multicenter study of posaconazole therapeutic drug monitoring: Exposure-response relationship and factors affecting concentration
    • Dolton MJ, Ray JE, Chen SC, et al. Multicenter study of posaconazole therapeutic drug monitoring: exposure-response relationship and factors affecting concentration. Antimicrob Agents Chemother 2012; 56:5503-5510.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 5503-5510
    • Dolton, M.J.1    Ray, J.E.2    Chen, S.C.3
  • 4
    • 84865423887 scopus 로고    scopus 로고
    • Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring
    • Dolton MJ, Ray JE, Chen SC, et al. Multicenter study of voriconazole pharmacokinetics and therapeutic drug monitoring. Antimicrob Agents Chemother 2012; 56:4793-4799.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4793-4799
    • Dolton, M.J.1    Ray, J.E.2    Chen, S.C.3
  • 5
    • 84879237440 scopus 로고    scopus 로고
    • Itraconazole: An update on pharmacology and clinical use for treatment of invasive and allergic fungal infections
    • Lestner J, Hope WW. Itraconazole: an update on pharmacology and clinical use for treatment of invasive and allergic fungal infections. Expert Opin Drug Metab Toxicol 2013; 9:911-926.
    • (2013) Expert Opin Drug Metab Toxicol , vol.9 , pp. 911-926
    • Lestner, J.1    Hope, W.W.2
  • 6
    • 24144435977 scopus 로고    scopus 로고
    • Making sense of itraconazole pharmacokinetics
    • Prentice AG, Glasmacher A. Making sense of itraconazole pharmacokinetics. J Antimicrob Chemother 2005; 56 (Suppl 1):i17-i22.
    • (2005) J Antimicrob Chemother , vol.56 , pp. i17-i22
    • Prentice, A.G.1    Glasmacher, A.2
  • 7
    • 62949244126 scopus 로고    scopus 로고
    • Pharmacokinetics and absorption of posaconazole oral suspension under various gastric conditions in healthy volunteers
    • Krishna G, Moton A, Ma L, et al. Pharmacokinetics and absorption of posaconazole oral suspension under various gastric conditions in healthy volunteers. Antimicrob Agents Chemother 2009; 53:958-966.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 958-966
    • Krishna, G.1    Moton, A.2    Ma, L.3
  • 8
    • 84903899191 scopus 로고    scopus 로고
    • Understanding variability with voriconazole using a population pharmacokinetic approach: Implications for optimal dosing
    • Dolton MJ, Mikus G, Weiss J, et al. Understanding variability with voriconazole using a population pharmacokinetic approach: implications for optimal dosing. J Antimicrob Chemother 2014; 69:1633-1641.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1633-1641
    • Dolton, M.J.1    Mikus, G.2    Weiss, J.3
  • 9
    • 84920396162 scopus 로고    scopus 로고
    • Azoles
    • Kauffman CA Pappas PG Sobel JD Dismukes WE editors. New York: Springer
    • Andes D, Dismukes W. Azoles. In: Kauffman CA, Pappas PG, Sobel JD, Dismukes WE, editors. Essentials of clinical mycology. New York: Springer; 2011. pp. 61-93.
    • (2011) Essentials of Clinical Mycology , pp. 61-93
    • Andes, D.1    Dismukes, W.2
  • 10
    • 84863184361 scopus 로고    scopus 로고
    • Risk factors for voriconazole hepatotoxicity at 12 weeks in lung transplant recipients
    • Luong M-L, Hosseini-Moghaddam SM, Singer LG, et al. Risk factors for voriconazole hepatotoxicity at 12 weeks in lung transplant recipients. Am J Transplant 2012; 12:1929-1935.
    • (2012) Am J Transplant , vol.12 , pp. 1929-1935
    • Luong, M.-L.1    Hosseini-Moghaddam, S.M.2    Singer, L.G.3
  • 11
    • 65549159077 scopus 로고    scopus 로고
    • Clinical relevance of the pharmacokinetic interactions of azole antifungal drugs with other coadministered agents
    • Brüggemann RJM, Alffenaar J-WC, Blijlevens NMA, et al. Clinical relevance of the pharmacokinetic interactions of azole antifungal drugs with other coadministered agents. Clin Infect Dis 2009; 48:1441-1458.
    • (2009) Clin Infect Dis , vol.48 , pp. 1441-1458
    • Brüggemann, R.J.M.1    Alffenaar, J.-W.C.2    Blijlevens, N.M.A.3
  • 12
    • 0025257110 scopus 로고
    • Pharmacokinetics and tissue penetration of fluconazole in humans
    • Brammer KW, Farrow PR, Faulkner JK. Pharmacokinetics and tissue penetration of fluconazole in humans. Rev Infect Dis 1990; 12 (Suppl 3):S318-S326.
    • (1990) Rev Infect Dis , vol.12 , pp. S318-S326
    • Brammer, K.W.1    Farrow, P.R.2    Faulkner, J.K.3
  • 13
    • 0035667773 scopus 로고    scopus 로고
    • Population pharmacokinetics of fluconazole given for secondary prevention of oropharyngeal candidiasis in HIV-positive patients
    • Csajka C, Décosterd L, Buclin T, et al. Population pharmacokinetics of fluconazole given for secondary prevention of oropharyngeal candidiasis in HIV-positive patients. Eur J Clin Pharmacol 2001; 57:723-727.
    • (2001) Eur J Clin Pharmacol , vol.57 , pp. 723-727
    • Csajka, C.1    Décosterd, L.2    Buclin, T.3
  • 14
    • 0029077096 scopus 로고
    • Pharmacokinetics and bioavailability of fluconazole in two groups of males with human immunodeficiency virus (HIV) infection compared with those in a group of males without HIV infection
    • Tett S, Moore S, Ray J. Pharmacokinetics and bioavailability of fluconazole in two groups of males with human immunodeficiency virus (HIV) infection compared with those in a group of males without HIV infection. Antimicrob Agents Chemother 1995; 39:1835-1841.
    • (1995) Antimicrob Agents Chemother , vol.39 , pp. 1835-1841
    • Tett, S.1    Moore, S.2    Ray, J.3
  • 15
    • 84898452706 scopus 로고    scopus 로고
    • Therapeutic drug monitoring (TDM) of antifungal agents: Guidelines from the British Society for Medical Mycology
    • Ashbee HR, Barnes RA, Johnson EM, et al. Therapeutic drug monitoring (TDM) of antifungal agents: guidelines from the British Society for Medical Mycology. J Antimicrob Chemother 2014; 69:1162-1176.
    • (2014) J Antimicrob Chemother , vol.69 , pp. 1162-1176
    • Ashbee, H.R.1    Barnes, R.A.2    Johnson, E.M.3
  • 18
    • 34848865974 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America
    • Wheat LJ, Freifeld AG, Kleiman MB, et al. Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America. Clin Infect Dis 2007; 45:807-825.
    • (2007) Clin Infect Dis , vol.45 , pp. 807-825
    • Wheat, L.J.1    Freifeld, A.G.2    Kleiman, M.B.3
  • 19
    • 46249094201 scopus 로고    scopus 로고
    • Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America
    • Chapman SW, Dismukes WE, Proia LA, et al. Clinical practice guidelines for the management of blastomycosis: 2008 update by the Infectious Diseases Society of America. Clin Infect Dis 2008; 46:1801-1812.
    • (2008) Clin Infect Dis , vol.46 , pp. 1801-1812
    • Chapman, S.W.1    Dismukes, W.E.2    Proia, L.A.3
  • 20
    • 39449095735 scopus 로고    scopus 로고
    • Treatment of aspergillosis: Clinical practice guidelines of the Infectious Diseases Society of America
    • Walsh TJ, Anaissie EJ, Denning DW, et al. Treatment of aspergillosis: clinical practice guidelines of the Infectious Diseases Society of America. Clin Infect Dis 2008; 46:327-360.
    • (2008) Clin Infect Dis , vol.46 , pp. 327-360
    • Walsh, T.J.1    Anaissie, E.J.2    Denning, D.W.3
  • 22
    • 0010589469 scopus 로고    scopus 로고
    • Intravenous itraconazole followed by oral itraconazole in the treatment of invasive pulmonary aspergillosis in patients with hematologic malignancies, chronic granulomatous disease, or AIDS
    • Caillot D, Bassaris H, McGeer A, et al. Intravenous itraconazole followed by oral itraconazole in the treatment of invasive pulmonary aspergillosis in patients with hematologic malignancies, chronic granulomatous disease, or AIDS. Clin Infect Dis 2001; 33:e83-e90.
    • (2001) Clin Infect Dis , vol.33 , pp. e83-e90
    • Caillot, D.1    Bassaris, H.2    McGeer, A.3
  • 23
    • 0023734842 scopus 로고
    • Pharmacokinetics of itraconazole following oral administration to normal volunteers
    • Hardin TC, Graybill JR, Fetchick R, et al. Pharmacokinetics of itraconazole following oral administration to normal volunteers. Antimicrob Agents Chemother 1988; 32:1310-1313.
    • (1988) Antimicrob Agents Chemother , vol.32 , pp. 1310-1313
    • Hardin, T.C.1    Graybill, J.R.2    Fetchick, R.3
  • 24
    • 0031922837 scopus 로고    scopus 로고
    • Effect of omeprazole on the pharmacokinetics of itraconazole
    • Jaruratanasirikul S, Sriwiriyajan S. Effect of omeprazole on the pharmacokinetics of itraconazole. Eur J Clin Pharmacol 1998; 54:159-161.
    • (1998) Eur J Clin Pharmacol , vol.54 , pp. 159-161
    • Jaruratanasirikul, S.1    Sriwiriyajan, S.2
  • 25
    • 0031808362 scopus 로고    scopus 로고
    • Enhanced bioavailability of itraconazole in hydroxypropyl-beta-cyclodextrin solution versus capsules in healthy volunteers
    • Barone JA, Moskovitz BL, Guarnieri J, et al. Enhanced bioavailability of itraconazole in hydroxypropyl-beta-cyclodextrin solution versus capsules in healthy volunteers. Antimicrob Agents Chemother 1998; 42:1862-1865.
    • (1998) Antimicrob Agents Chemother , vol.42 , pp. 1862-1865
    • Barone, J.A.1    Moskovitz, B.L.2    Guarnieri, J.3
  • 26
    • 0027532084 scopus 로고
    • Food interaction and steady-state pharmacokinetics of itraconazole capsules in healthy male volunteers
    • Barone JA, Koh JG, Bierman RH, et al. Food interaction and steady-state pharmacokinetics of itraconazole capsules in healthy male volunteers. Antimicrob Agents Chemother 1993; 37:778-784.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 778-784
    • Barone, J.A.1    Koh, J.G.2    Bierman, R.H.3
  • 27
    • 0031919504 scopus 로고    scopus 로고
    • Food interaction and steady-state pharmacokinetics of itraconazole oral solution in healthy volunteers
    • Barone JA, Moskovitz BL, Guarnieri J, et al. Food interaction and steady-state pharmacokinetics of itraconazole oral solution in healthy volunteers. Pharmacotherapy 1998; 18:295-301.
    • (1998) Pharmacotherapy , vol.18 , pp. 295-301
    • Barone, J.A.1    Moskovitz, B.L.2    Guarnieri, J.3
  • 28
    • 4644274436 scopus 로고    scopus 로고
    • Intrapulmonary pharmacokinetics and pharmacodynamics of itraconazole and 14-hydroxyitraconazole at steady state
    • Conte JE, Golden JA, Kipps J, et al. Intrapulmonary pharmacokinetics and pharmacodynamics of itraconazole and 14-hydroxyitraconazole at steady state. Antimicrob Agents Chemother 2004; 48:3823-3827.
    • (2004) Antimicrob Agents Chemother , vol.48 , pp. 3823-3827
    • Conte, J.E.1    Golden, J.A.2    Kipps, J.3
  • 29
    • 0029595358 scopus 로고
    • Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin
    • Ducharme MP, Slaughter RL, Warbasse LH, et al. Itraconazole and hydroxyitraconazole serum concentrations are reduced more than tenfold by phenytoin. Clin Pharmacol Ther 1995; 58:617-624.
    • (1995) Clin Pharmacol Ther , vol.58 , pp. 617-624
    • Ducharme, M.P.1    Slaughter, R.L.2    Warbasse, L.H.3
  • 30
    • 0028275659 scopus 로고
    • Bioassay for serum itraconazole concentrations using hydroxyitraconazole standards
    • Law D, Moore CB, Denning DW. Bioassay for serum itraconazole concentrations using hydroxyitraconazole standards. Antimicrob Agents Chemother 1994; 38:1561-1566.
    • (1994) Antimicrob Agents Chemother , vol.38 , pp. 1561-1566
    • Law, D.1    Moore, C.B.2    Denning, D.W.3
  • 31
    • 84891511941 scopus 로고    scopus 로고
    • A reference laboratory experience of clinically achievable voriconazole, posaconazole, and itraconazole concentrations within the bloodstream and cerebral spinal fluid
    • Wiederhold NP, Pennick GJ, Dorsey SA, et al. A reference laboratory experience of clinically achievable voriconazole, posaconazole, and itraconazole concentrations within the bloodstream and cerebral spinal fluid. Antimicrob Agents Chemother 2014; 58:424-431.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 424-431
    • Wiederhold, N.P.1    Pennick, G.J.2    Dorsey, S.A.3
  • 32
    • 0024847184 scopus 로고
    • The clinical pharmacokinetics of itraconazole: An overview
    • Heykants J, van Peer A, Van de Velde V, et al. The clinical pharmacokinetics of itraconazole: an overview. Mycoses 1989; 32 (Suppl 1):67-87.
    • (1989) Mycoses , vol.32 , pp. 67-87
    • Heykants, J.1    Van Peer, A.2    Van De Velde, V.3
  • 33
    • 0027998573 scopus 로고
    • Comparison of in vitro antifungal activity of itraconazole and hydroxy-itraconazole by colorimetric MTT assay
    • Mikami Y, Sakamoto T, Yazawa K, et al. Comparison of in vitro antifungal activity of itraconazole and hydroxy-itraconazole by colorimetric MTT assay. Mycoses 1994; 37:27-33.
    • (1994) Mycoses , vol.37 , pp. 27-33
    • Mikami, Y.1    Sakamoto, T.2    Yazawa, K.3
  • 34
    • 0034094331 scopus 로고    scopus 로고
    • Antifungal activity of itraconazole compared with hydroxy-itraconazole in vitro
    • Odds FC, Bossche HV. Antifungal activity of itraconazole compared with hydroxy-itraconazole in vitro. J Antimicrob Chemother 2000; 45:371-373.
    • (2000) J Antimicrob Chemother , vol.45 , pp. 371-373
    • Odds, F.C.1    Bossche, H.V.2
  • 35
    • 0032949890 scopus 로고    scopus 로고
    • Bioassays for itraconazole blood levels: An interlaboratory collaborative study
    • Odds FC, Dupont B, Rinaldi MG, et al. Bioassays for itraconazole blood levels: an interlaboratory collaborative study. J Antimicrob Chemother 1999; 43:723-727.
    • (1999) J Antimicrob Chemother , vol.43 , pp. 723-727
    • Odds, F.C.1    Dupont, B.2    Rinaldi, M.G.3
  • 36
    • 0027500871 scopus 로고
    • Discrepancies in bioassay and chromatography determinations explained by metabolism of itraconazole to hydroxyitraconazole: Studies of interpatient variations in concentrations
    • Hostetler JS, Heykants J, Clemons KV, et al. Discrepancies in bioassay and chromatography determinations explained by metabolism of itraconazole to hydroxyitraconazole: studies of interpatient variations in concentrations. Antimicrob Agents Chemother 1993; 37:2224-2227.
    • (1993) Antimicrob Agents Chemother , vol.37 , pp. 2224-2227
    • Hostetler, J.S.1    Heykants, J.2    Clemons, K.V.3
  • 37
    • 33645103422 scopus 로고    scopus 로고
    • Stereochemical aspects of itraconazole metabolism in vitro and in vivo
    • Kunze KL, Nelson WL, Kharasch ED, et al. Stereochemical aspects of itraconazole metabolism in vitro and in vivo. Drug Metab Dispos 2006; 34:583-590.
    • (2006) Drug Metab Dispos , vol.34 , pp. 583-590
    • Kunze, K.L.1    Nelson, W.L.2    Kharasch, E.D.3
  • 38
    • 77955905585 scopus 로고    scopus 로고
    • Impact of absolute stereochemistry on the antiangiogenic and antifungal activities of itraconazole
    • Shi W, Nacev BA, Bhat S, Liu JO. Impact of absolute stereochemistry on the antiangiogenic and antifungal activities of itraconazole. ACS Med Chem Lett 2010; 1:155-159.
    • (2010) ACS Med Chem Lett , vol.1 , pp. 155-159
    • Shi, W.1    Nacev, B.A.2    Bhat, S.3    Liu, J.O.4
  • 39
    • 79959936146 scopus 로고    scopus 로고
    • Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection
    • Pyrgaki C, Bannister SJ, Gera L, et al. Stereoselective determination of the epimer mixtures of itraconazole in human blood plasma using HPLC and fluorescence detection. Chirality 2011; 23:495-503.
    • (2011) Chirality , vol.23 , pp. 495-503
    • Pyrgaki, C.1    Bannister, S.J.2    Gera, L.3
  • 40
    • 0024916061 scopus 로고
    • Antifungal prophylaxis with itraconazole in prolonged neutropenia: Correlation with plasma levels
    • Boogaerts MA, Verhoef GE, Zachee P, et al. Antifungal prophylaxis with itraconazole in prolonged neutropenia: correlation with plasma levels. Mycoses 1989; 32 (Suppl 1):103-108.
    • (1989) Mycoses , vol.32 , pp. 103-108
    • Boogaerts, M.A.1    Verhoef, G.E.2    Zachee, P.3
  • 41
    • 0032886182 scopus 로고    scopus 로고
    • Breakthrough invasive fungal infections in neutropenic patients after prophylaxis with itraconazole
    • Glasmacher A, Hahn C, Leutner C, et al. Breakthrough invasive fungal infections in neutropenic patients after prophylaxis with itraconazole. Mycoses 1999; 42:443-451.
    • (1999) Mycoses , vol.42 , pp. 443-451
    • Glasmacher, A.1    Hahn, C.2    Leutner, C.3
  • 42
    • 1542438612 scopus 로고    scopus 로고
    • Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies: Evidence from a meta-analysis of 3597 patients
    • Glasmacher A, Prentice A, Gorschlü ter M, et al. Itraconazole prevents invasive fungal infections in neutropenic patients treated for hematologic malignancies: evidence from a meta-analysis of 3,597 patients. J Clin Oncol 2003; 21:4615-4626.
    • (2003) J Clin Oncol , vol.21 , pp. 4615-4626
    • Glasmacher, A.1    Prentice, A.2    Gorschlü Ter, M.3
  • 43
    • 0028029402 scopus 로고
    • NIAID Mycoses Study Group multicenter trial of oral itraconazole therapy for invasive aspergillosis
    • Denning DW, Lee JY, Hostetler JS, et al. NIAID Mycoses Study Group multicenter trial of oral itraconazole therapy for invasive aspergillosis. Am J Med 1994; 97:135-144.
    • (1994) Am J Med , vol.97 , pp. 135-144
    • Denning, D.W.1    Lee, J.Y.2    Hostetler, J.S.3
  • 44
    • 70049102699 scopus 로고    scopus 로고
    • Toxicodynamics of itraconazole: Implications for therapeutic drug monitoring
    • Lestner JM, Roberts SA, Moore CB, et al. Toxicodynamics of itraconazole: implications for therapeutic drug monitoring. Clin Infect Dis 2009; 49:928-930.
    • (2009) Clin Infect Dis , vol.49 , pp. 928-930
    • Lestner, J.M.1    Roberts, S.A.2    Moore, C.B.3
  • 45
    • 77649159189 scopus 로고    scopus 로고
    • Tremor: A newly described adverse event with long-term itraconazole therapy
    • Lestner JM, Denning DW. Tremor: a newly described adverse event with long-term itraconazole therapy. J Neurol Neurosurg Psychiatry 2010; 81:327-329.
    • (2010) J Neurol Neurosurg Psychiatry , vol.81 , pp. 327-329
    • Lestner, J.M.1    Denning, D.W.2
  • 46
    • 0037043655 scopus 로고    scopus 로고
    • Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis
    • Herbrecht R, Denning DW, Patterson TF, et al. Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis. N Engl J Med 2002; 347:408-415.
    • (2002) N Engl J Med , vol.347 , pp. 408-415
    • Herbrecht, R.1    Denning, D.W.2    Patterson, T.F.3
  • 47
    • 0038556830 scopus 로고    scopus 로고
    • Voriconazole treatment for less-common emerging or refractory fungal infections
    • Perfect JR, Marr KA, Walsh TJ, et al. Voriconazole treatment for less-common, emerging, or refractory fungal infections. Clin Infect Dis2003;36:1122-1131.
    • (2003) Clin Infect Dis , vol.36 , pp. 1122-1131
    • Perfect, J.R.1    Marr, K.A.2    Walsh, T.J.3
  • 48
    • 33751173454 scopus 로고    scopus 로고
    • Voriconazole prophylaxis in lung transplant recipients
    • Husain S, Paterson DL, Studer S, et al. Voriconazole prophylaxis in lung transplant recipients. Am J Transplant 2006; 6:3008-3016.
    • (2006) Am J Transplant , vol.6 , pp. 3008-3016
    • Husain, S.1    Paterson, D.L.2    Studer, S.3
  • 49
    • 34548062677 scopus 로고    scopus 로고
    • Breakthrough fungal infections after allogeneic hematopoietic stem cell transplantation in patients on prophylactic voriconazole
    • Trifilio S, Singhal S, Williams S, et al. Breakthrough fungal infections after allogeneic hematopoietic stem cell transplantation in patients on prophylactic voriconazole. Bone Marrow Transplant 2007; 40:451-456.
    • (2007) Bone Marrow Transplant , vol.40 , pp. 451-456
    • Trifilio, S.1    Singhal, S.2    Williams, S.3
  • 50
    • 38049153781 scopus 로고    scopus 로고
    • Update on the treatment of disseminated fusariosis: Focus on voriconazole
    • Stanzani M, Tumietto F, Vianelli N, Baccarani M. Update on the treatment of disseminated fusariosis: focus on voriconazole. Ther Clin Risk Manag 2007; 3:1165-1173.
    • (2007) Ther Clin Risk Manag , vol.3 , pp. 1165-1173
    • Stanzani, M.1    Tumietto, F.2    Vianelli, N.3    Baccarani, M.4
  • 51
    • 0037371527 scopus 로고    scopus 로고
    • Voriconazole: A new triazole antifungal agent
    • Johnson LB, Kauffman CA. Voriconazole: a new triazole antifungal agent. Clin Infect Dis 2003; 36:630-637.
    • (2003) Clin Infect Dis , vol.36 , pp. 630-637
    • Johnson, L.B.1    Kauffman, C.A.2
  • 52
    • 84874213705 scopus 로고    scopus 로고
    • Voriconazole therapeutic drug monitoring: Retrospective cohort study of the relationship to clinical outcomes and adverse events
    • Chu HY, Jain R, Xie H, et al. Voriconazole therapeutic drug monitoring: retrospective cohort study of the relationship to clinical outcomes and adverse events. BMC Infect Dis 2013; 13:105.
    • (2013) BMC Infect Dis , vol.13 , pp. 105
    • Chu, H.Y.1    Jain, R.2    Xie, H.3
  • 53
    • 77954630521 scopus 로고    scopus 로고
    • Voriconazole concentrations and outcome of invasive fungal infections
    • Miyakis S, van Hal SJ, Ray J, Marriott D. Voriconazole concentrations and outcome of invasive fungal infections. Clin Microbiol Infect 2010; 16:927-933.
    • (2010) Clin Microbiol Infect , vol.16 , pp. 927-933
    • Miyakis, S.1    Van Hal, S.J.2    Ray, J.3    Marriott, D.4
  • 54
    • 84867568482 scopus 로고    scopus 로고
    • Monitoring trough voriconazole plasma concentrations in haematological patients: Real life multicentre experience
    • Racil Z, Winterova J, Kouba M, et al. Monitoring trough voriconazole plasma concentrations in haematological patients: real life multicentre experience. Mycoses 2012; 55:483-492.
    • (2012) Mycoses , vol.55 , pp. 483-492
    • Racil, Z.1    Winterova, J.2    Kouba, M.3
  • 55
    • 84886294113 scopus 로고    scopus 로고
    • Steady-state pharmacokinetics and metabolism of voriconazole in patients
    • Geist MJP, Egerer G, Burhenne J, et al. Steady-state pharmacokinetics and metabolism of voriconazole in patients. J Antimicrob Chemother 2013; 68:2592-2599.
    • (2013) J Antimicrob Chemother , vol.68 , pp. 2592-2599
    • Geist, M.J.P.1    Egerer, G.2    Burhenne, J.3
  • 56
    • 0036498964 scopus 로고    scopus 로고
    • Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis
    • Denning DW, Ribaud P, Milpied N, et al. Efficacy and safety of voriconazole in the treatment of acute invasive aspergillosis. Clin Infect Dis 2002; 34:563-571.
    • (2002) Clin Infect Dis , vol.34 , pp. 563-571
    • Denning, D.W.1    Ribaud, P.2    Milpied, N.3
  • 57
    • 39449117139 scopus 로고    scopus 로고
    • Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes
    • Pascual A, Calandra T, Bolay S, et al. Voriconazole therapeutic drug monitoring in patients with invasive mycoses improves efficacy and safety outcomes. Clin Infect Dis 2008; 46:201-211.
    • (2008) Clin Infect Dis , vol.46 , pp. 201-211
    • Pascual, A.1    Calandra, T.2    Bolay, S.3
  • 58
    • 67749101112 scopus 로고    scopus 로고
    • Monitoring trough concentration of voriconazole is important to ensure successful antifungal therapy and to avoid hepatic damage in patients with hematological disorders
    • Ueda K, Nannya Y, Kumano K, et al. Monitoring trough concentration of voriconazole is important to ensure successful antifungal therapy and to avoid hepatic damage in patients with hematological disorders. Int J Hematol 2009; 89:592-599.
    • (2009) Int J Hematol , vol.89 , pp. 592-599
    • Ueda, K.1    Nannya, Y.2    Kumano, K.3
  • 59
    • 0035991878 scopus 로고    scopus 로고
    • Pharmacokinetics and safety of voriconazole following intravenous-to oral-dose escalation regimens
    • Purkins L, Wood N, Ghahramani P, et al. Pharmacokinetics and safety of voriconazole following intravenous-to oral-dose escalation regimens. Antimicrob Agents Chemother 2002; 46:2546-2553.
    • (2002) Antimicrob Agents Chemother , vol.46 , pp. 2546-2553
    • Purkins, L.1    Wood, N.2    Ghahramani, P.3
  • 60
    • 0037403687 scopus 로고    scopus 로고
    • Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole
    • Hyland R, Jones BC, Smith DA. Identification of the cytochrome P450 enzymes involved in the N-oxidation of voriconazole. Drug Metab Dispos 2003; 31:540-547.
    • (2003) Drug Metab Dispos , vol.31 , pp. 540-547
    • Hyland, R.1    Jones, B.C.2    Smith, D.A.3
  • 61
    • 30344457586 scopus 로고    scopus 로고
    • A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants
    • Sim SC, Risinger C, Dahl M-L, et al. A common novel CYP2C19 gene variant causes ultrarapid drug metabolism relevant for the drug response to proton pump inhibitors and antidepressants. Clin Pharmacol Ther 2006; 79:103-113.
    • (2006) Clin Pharmacol Ther , vol.79 , pp. 103-113
    • Sim, S.C.1    Risinger, C.2    Dahl, M.-L.3
  • 62
    • 84868025932 scopus 로고    scopus 로고
    • Transcriptional regulation of CYP2C19 and its role in altered enzyme activity
    • Uppugunduri CRS, Daali Y, Desmeules J, et al. Transcriptional regulation of CYP2C19 and its role in altered enzyme activity. Curr Drug Metab 2012; 13:1196-1204.
    • (2012) Curr Drug Metab , vol.13 , pp. 1196-1204
    • Uppugunduri, C.R.S.1    Daali, Y.2    Desmeules, J.3
  • 63
    • 84863011832 scopus 로고    scopus 로고
    • Effect of CYP2C19 polymorphism on the pharmacokinetics of voriconazole after single and multiple doses in healthy volunteers
    • Lee S, Kim B-H, Nam W-S, et al. Effect of CYP2C19 polymorphism on the pharmacokinetics of voriconazole after single and multiple doses in healthy volunteers. J Clin Pharmacol 2013; 52:195-203.
    • (2013) J Clin Pharmacol , vol.52 , pp. 195-203
    • Lee, S.1    Kim, B.-H.2    Nam, W.-S.3
  • 64
    • 70849109113 scopus 로고    scopus 로고
    • Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype
    • Scholz I, Oberwittler H, Riedel K-D, et al. Pharmacokinetics, metabolism and bioavailability of the triazole antifungal agent voriconazole in relation to CYP2C19 genotype. Br J Clin Pharmacol 2009; 68:906-915.
    • (2009) Br J Clin Pharmacol , vol.68 , pp. 906-915
    • Scholz, I.1    Oberwittler, H.2    Riedel, K.-D.3
  • 65
    • 79951828765 scopus 로고    scopus 로고
    • Fluoride excess and periostitis in transplant patients receiving long-termvoriconazole therapy
    • Wermers RA, Cooper K, Razonable RR, et al. Fluoride excess and periostitis in transplant patients receiving long-termvoriconazole therapy. Clin Infect Dis 2011; 52:604-611.
    • (2011) Clin Infect Dis , vol.52 , pp. 604-611
    • Wermers, R.A.1    Cooper, K.2    Razonable, R.R.3
  • 66
    • 84455192484 scopus 로고    scopus 로고
    • Fluoride excess in coccidioidomycosis patients receiving long-term antifungal therapy: An assessment of currently available triazoles
    • Thompson GR, Bays D, Cohen SH, Pappagianis D. Fluoride excess in coccidioidomycosis patients receiving long-term antifungal therapy: an assessment of currently available triazoles. Antimicrob Agents Chemother 2012; 56:563-564.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 563-564
    • Thompson, G.R.1    Bays, D.2    Cohen, S.H.3    Pappagianis, D.4
  • 67
    • 84866595590 scopus 로고    scopus 로고
    • Reversible skeletal disease and high fluoride serum levels in hematologic patients receiving voriconazole
    • Gerber B, Guggenberger R, Fasler D, et al. Reversible skeletal disease and high fluoride serum levels in hematologic patients receiving voriconazole. Blood 2012; 120:2390-2394.
    • (2012) Blood , vol.120 , pp. 2390-2394
    • Gerber, B.1    Guggenberger, R.2    Fasler, D.3
  • 68
    • 84908671512 scopus 로고    scopus 로고
    • Voriconazole-associated cutaneous malignancy: A literature review on photocarcinogenesis in organ transplant recipients
    • Williams K, Mansh M, Chin-Hong P, et al. Voriconazole-associated cutaneous malignancy: a literature review on photocarcinogenesis in organ transplant recipients. Clin Infect Dis 2014; 58:997-1002.
    • (2014) Clin Infect Dis , vol.58 , pp. 997-1002
    • Williams, K.1    Mansh, M.2    Chin-Hong, P.3
  • 70
    • 84904977861 scopus 로고    scopus 로고
    • Alopecia and nail changes associated with voriconazole therapy
    • Malani AN, Kerr L, Obear J, et al. Alopecia and nail changes associated with voriconazole therapy. Clin Infect Dis 2014; 59:e61-e65.
    • (2014) Clin Infect Dis , vol.59 , pp. e61-e65
    • Malani, A.N.1    Kerr, L.2    Obear, J.3
  • 71
    • 31344478761 scopus 로고    scopus 로고
    • Investigation of the potential relationships between plasma voriconazole concentrations and visual adverse events or liver function test abnormalities
    • Tan K, Brayshaw N, Tomaszewski K, et al. Investigation of the potential relationships between plasma voriconazole concentrations and visual adverse events or liver function test abnormalities. J Clin Pharmacol 2006; 46:235-243.
    • (2006) J Clin Pharmacol , vol.46 , pp. 235-243
    • Tan, K.1    Brayshaw, N.2    Tomaszewski, K.3
  • 72
    • 80052859006 scopus 로고    scopus 로고
    • Observational study of the clinical efficacy of voriconazole and its relationship to plasma concentrations in patients
    • Troke PF, Hockey HP, Hope WW. Observational study of the clinical efficacy of voriconazole and its relationship to plasma concentrations in patients. Antimicrob Agents Chemother 2011; 55:4782-4788.
    • (2011) Antimicrob Agents Chemother , vol.55 , pp. 4782-4788
    • Troke, P.F.1    Hockey, H.P.2    Hope, W.W.3
  • 73
    • 84865137573 scopus 로고    scopus 로고
    • Investigation and threshold of optimum blood concentration of voriconazole: A descriptive statistical metaanalysis
    • Hamada Y, Seto Y, Yago K, Kuroyama M. Investigation and threshold of optimum blood concentration of voriconazole: a descriptive statistical metaanalysis. J Infect Chemother 2012; 18:501-507.
    • (2012) J Infect Chemother , vol.18 , pp. 501-507
    • Hamada, Y.1    Seto, Y.2    Yago, K.3    Kuroyama, M.4
  • 74
    • 84863925051 scopus 로고    scopus 로고
    • Challenging recommended oral and intravenous voriconazole doses for improved efficacy and safety: Population pharmacokinetics-based analysis of adult patients with invasive fungal infections
    • Pascual A, Csajka C, Buclin T, et al. Challenging recommended oral and intravenous voriconazole doses for improved efficacy and safety: population pharmacokinetics-based analysis of adult patients with invasive fungal infections. Clin Infect Dis 2012; 55:381-390.
    • (2012) Clin Infect Dis , vol.55 , pp. 381-390
    • Pascual, A.1    Csajka, C.2    Buclin, T.3
  • 75
    • 85027943028 scopus 로고    scopus 로고
    • Voriconazole pharmacokinetics and exposure-response relationships: Assessing the links between exposure, efficacy and toxicity
    • Dolton MJ, McLachlan AJ. Voriconazole pharmacokinetics and exposure-response relationships: Assessing the links between exposure, efficacy and toxicity. Int J Antimicrob Agents 2014; 44:183-193.
    • (2014) Int J Antimicrob Agents , vol.44 , pp. 183-193
    • Dolton, M.J.1    McLachlan, A.J.2
  • 76
    • 84901806364 scopus 로고    scopus 로고
    • Voriconazole metabolism, toxicity, and the effect of cytochrome P450 2C19 genotype
    • Zonios D, Yamazaki H, Murayama N, et al. Voriconazole metabolism, toxicity, and the effect of cytochrome P450 2C19 genotype. J Infect Dis 2014; 209:1941-1948.
    • (2014) J Infect Dis , vol.209 , pp. 1941-1948
    • Zonios, D.1    Yamazaki, H.2    Murayama, N.3
  • 77
    • 84861142646 scopus 로고    scopus 로고
    • Integrated population pharmacokinetic analysis of voriconazole in children, adolescents, and adults
    • Friberg LE, Ravva P, Karlsson MO, Liu P. Integrated population pharmacokinetic analysis of voriconazole in children, adolescents, and adults. Antimicrob Agents Chemother 2012; 56:3032-3042.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 3032-3042
    • Friberg, L.E.1    Ravva, P.2    Karlsson, M.O.3    Liu, P.4
  • 78
    • 84455161599 scopus 로고    scopus 로고
    • Population pharmacokinetics of voriconazole in adults
    • Hope WW. Population pharmacokinetics of voriconazole in adults. Antimicrob Agents Chemother 2012; 56:526-531.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 526-531
    • Hope, W.W.1
  • 79
    • 79751482504 scopus 로고    scopus 로고
    • Population pharmacokinetic evaluation with external validation and bayesian estimator of voriconazole in liver transplant recipients
    • Han K, Bies R, Johnson H, et al. Population pharmacokinetic evaluation with external validation and bayesian estimator of voriconazole in liver transplant recipients. Clin Pharmacokinet 2011; 50:201-214.
    • (2011) Clin Pharmacokinet , vol.50 , pp. 201-214
    • Han, K.1    Bies, R.2    Johnson, H.3
  • 80
    • 84875135343 scopus 로고    scopus 로고
    • Software for dosage individualization of voriconazole for immunocompromised patients
    • Hope WW, VanGuilder M, Donnelly JP, et al. Software for dosage individualization of voriconazole for immunocompromised patients. Antimicrob Agents Chemother 2013; 57:1888-1894.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 1888-1894
    • Hope, W.W.1    Vanguilder, M.2    Donnelly, J.P.3
  • 81
    • 0026596701 scopus 로고
    • Bayesian parameter estimation and population pharmacokinetics
    • Thomson AH, Whiting B. Bayesian parameter estimation and population pharmacokinetics. Clin Pharmacokinet 1992; 22:447-467.
    • (1992) Clin Pharmacokinet , vol.22 , pp. 447-467
    • Thomson, A.H.1    Whiting, B.2
  • 82
    • 84877886428 scopus 로고    scopus 로고
    • Comparing dose prediction software used to manage gentamicin dosing
    • Wong C, Kumar SS, Graham GG, et al. Comparing dose prediction software used to manage gentamicin dosing. Intern Med J 2013; 43:519-525.
    • (2013) Intern Med J , vol.43 , pp. 519-525
    • Wong, C.1    Kumar, S.S.2    Graham, G.G.3
  • 83
    • 84873039250 scopus 로고    scopus 로고
    • A Bayesian dose-individualization method for warfarin
    • Wright DB, Duffull S. A Bayesian dose-individualization method for warfarin. Clin Pharmacokinet 2013; 52:59-68.
    • (2013) Clin Pharmacokinet , vol.52 , pp. 59-68
    • Wright, D.B.1    Duffull, S.2
  • 84
    • 70449368823 scopus 로고    scopus 로고
    • Tacrolimus population pharmacokinetic-pharmacogenetic analysis and Bayesian estimation in renal transplant recipients
    • Benkali K, Prémaud A, Picard N, et al. Tacrolimus population pharmacokinetic-pharmacogenetic analysis and Bayesian estimation in renal transplant recipients. Clin Pharmacokinet 2009; 48:805-816.
    • (2009) Clin Pharmacokinet , vol.48 , pp. 805-816
    • Benkali, K.1    Prémaud, A.2    Picard, N.3
  • 85
    • 33846462456 scopus 로고    scopus 로고
    • Posaconazole vs. Fluconazole or itraconazole prophylaxis in patients with neutropenia
    • Cornely OA, Maertens J, Winston DJ, et al. Posaconazole vs. fluconazole or itraconazole prophylaxis in patients with neutropenia. N Engl J Med 2007; 356:348-359.
    • (2007) N Engl J Med , vol.356 , pp. 348-359
    • Cornely, O.A.1    Maertens, J.2    Winston, D.J.3
  • 86
    • 33846410666 scopus 로고    scopus 로고
    • Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease
    • Ullmann AJ, Lipton JH, Vesole DH, et al. Posaconazole or fluconazole for prophylaxis in severe graft-versus-host disease. N Engl J Med 2007; 356:335-347.
    • (2007) N Engl J Med , vol.356 , pp. 335-347
    • Ullmann, A.J.1    Lipton, J.H.2    Vesole, D.H.3
  • 87
    • 33646445731 scopus 로고    scopus 로고
    • Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions
    • Raad II, Hachem RY, Herbrecht R, et al. Posaconazole as salvage treatment for invasive fusariosis in patients with underlying hematologic malignancy and other conditions. Clin Infect Dis 2006; 42:1398-1403.
    • (2006) Clin Infect Dis , vol.42 , pp. 1398-1403
    • Raad, I.I.1    Hachem, R.Y.2    Herbrecht, R.3
  • 88
    • 33845710284 scopus 로고    scopus 로고
    • Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: An externally controlled trial
    • Walsh TJ, Raad I, Patterson TF, et al. Treatment of invasive aspergillosis with posaconazole in patients who are refractory to or intolerant of conventional therapy: an externally controlled trial. Clin Infect Dis 2007; 44:2-12.
    • (2007) Clin Infect Dis , vol.44 , pp. 2-12
    • Walsh, T.J.1    Raad, I.2    Patterson, T.F.3
  • 89
    • 28044445699 scopus 로고    scopus 로고
    • Posaconazole: A broad-spectrum triazole antifungal
    • Torres HA, Hachem RY, Chemaly RF, et al. Posaconazole: a broad-spectrum triazole antifungal. Lancet Infect Dis 2005; 5:775-785.
    • (2005) Lancet Infect Dis , vol.5 , pp. 775-785
    • Torres, H.A.1    Hachem, R.Y.2    Chemaly, R.F.3
  • 90
    • 84897065789 scopus 로고    scopus 로고
    • Comparison of itraconazole, voriconazole, and posaconazole as oral antifungal prophylaxis in pediatric patients following allogeneic hematopoietic stem cell transplantation
    • Döring M, Blume O, Haufe S, et al. Comparison of itraconazole, voriconazole, and posaconazole as oral antifungal prophylaxis in pediatric patients following allogeneic hematopoietic stem cell transplantation. Eur J Clin Microbiol Infect Dis 2014; 33:629-638.
    • (2014) Eur J Clin Microbiol Infect Dis , vol.33 , pp. 629-638
    • Döring, M.1    Blume, O.2    Haufe, S.3
  • 91
    • 84861116449 scopus 로고    scopus 로고
    • Posaconazole exposure-response relationship: Evaluating the utility of therapeutic drug monitoring
    • Dolton MJ, Ray JE, Marriott D, McLachlan AJ. Posaconazole exposure-response relationship: evaluating the utility of therapeutic drug monitoring. Antimicrob Agents Chemother 2012; 56:2806-2813.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 2806-2813
    • Dolton, M.J.1    Ray, J.E.2    Marriott, D.3    McLachlan, A.J.4
  • 92
    • 13244268757 scopus 로고    scopus 로고
    • Oral bioavailability of posaconazole in fasted healthy subjects: Comparison between three regimens and basis for clinical dosage recommendations
    • Ezzet F, Wexler D, Courtney R, et al. Oral bioavailability of posaconazole in fasted healthy subjects: comparison between three regimens and basis for clinical dosage recommendations. Clin Pharmacokinet 2005; 44:211-220.
    • (2005) Clin Pharmacokinet , vol.44 , pp. 211-220
    • Ezzet, F.1    Wexler, D.2    Courtney, R.3
  • 93
    • 77953809369 scopus 로고    scopus 로고
    • Exposure-response of posaconazole used for prophylaxis against invasive fungal infections: Evaluating the need to adjust doses based on drug concentrations in plasma
    • Jang SH, Colangelo PM, Gobburu JVS. Exposure-response of posaconazole used for prophylaxis against invasive fungal infections: evaluating the need to adjust doses based on drug concentrations in plasma. Clin Pharmacol Ther 2010; 88:115-119.
    • (2010) Clin Pharmacol Ther , vol.88 , pp. 115-119
    • Jang, S.H.1    Colangelo, P.M.2    Gobburu, J.V.S.3
  • 94
    • 66149083562 scopus 로고    scopus 로고
    • Posaconazole therapeutic drug monitoring: A reference laboratory experience
    • Thompson GR, Rinaldi MG, Pennick G, et al. Posaconazole therapeutic drug monitoring: a reference laboratory experience. Antimicrob Agents Chemother 2009; 53:2223-2224.
    • (2009) Antimicrob Agents Chemother , vol.53 , pp. 2223-2224
    • Thompson, G.R.1    Rinaldi, M.G.2    Pennick, G.3
  • 95
    • 79951949693 scopus 로고    scopus 로고
    • A postmarketing evaluation of posaconazole plasma concentrations in neutropenic patients with haematological malignancy receiving posaconazole prophylaxis
    • Bryant AM, Slain D, Cumpston A, Craig M. A postmarketing evaluation of posaconazole plasma concentrations in neutropenic patients with haematological malignancy receiving posaconazole prophylaxis. Int J Antimicrob Agents 2011; 37:266-269.
    • (2011) Int J Antimicrob Agents , vol.37 , pp. 266-269
    • Bryant, A.M.1    Slain, D.2    Cumpston, A.3    Craig, M.4
  • 96
    • 80051792869 scopus 로고    scopus 로고
    • Posaconazole plasma concentrations in critically ill patients
    • Ray J, Campbell L, Rudham S, et al. Posaconazole plasma concentrations in critically ill patients. Ther Drug Monit 2011; 33:387-392.
    • (2011) Ther Drug Monit , vol.33 , pp. 387-392
    • Ray, J.1    Campbell, L.2    Rudham, S.3
  • 97
    • 84857058536 scopus 로고    scopus 로고
    • Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: Influence of food intake
    • Eiden C, Meniane JC, Peyriè re H, et al. Therapeutic drug monitoring of posaconazole in hematology adults under posaconazole prophylaxis: influence of food intake. Eur J Clin Microbiol Infect Dis 2012; 31:161-167.
    • (2012) Eur J Clin Microbiol Infect Dis , vol.31 , pp. 161-167
    • Eiden, C.1    Meniane, J.C.2    Peyriè Re, H.3
  • 98
    • 84860477358 scopus 로고    scopus 로고
    • Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies
    • Hoenigl M, Raggam RB, Salzer HJF, et al. Posaconazole plasma concentrations and invasive mould infections in patients with haematological malignancies. Int J Antimicrob Agents 2012; 39:510-513.
    • (2012) Int J Antimicrob Agents , vol.39 , pp. 510-513
    • Hoenigl, M.1    Raggam, R.B.2    Salzer, H.J.F.3
  • 101
    • 84903125981 scopus 로고    scopus 로고
    • Posaconazole tablet pharmacokinetics: Lack of effect of concomitant medications altering gastric pH and gastric motility in healthy subjects
    • Kraft WK, Chang PS, van Iersel MLPS, et al. Posaconazole tablet pharmacokinetics: lack of effect of concomitant medications altering gastric pH and gastric motility in healthy subjects. Antimicrob Agents Chemother 2014; 58:4020-4025.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 4020-4025
    • Kraft, W.K.1    Chang, P.S.2    Van Iersel, M.L.P.S.3
  • 102
    • 84864381308 scopus 로고    scopus 로고
    • Single-dose phase i study to evaluate the pharmacokinetics of posaconazole in new tablet and capsule formulations relative to oral suspension
    • Krishna G, Ma L, Martinho M, et al. Single-dose phase I study to evaluate the pharmacokinetics of posaconazole in new tablet and capsule formulations relative to oral suspension. Antimicrob Agents Chemother 2012; 56:4196-4201.
    • (2012) Antimicrob Agents Chemother , vol.56 , pp. 4196-4201
    • Krishna, G.1    Ma, L.2    Martinho, M.3
  • 104
    • 84867584428 scopus 로고    scopus 로고
    • A new solid oral tablet formulation of posaconazole: A randomized clinical trial to investigate rising single-and multiple-dose pharmacokinetics and safety in healthy volunteers
    • Krishna G, Ma L, Martinho M, et al. A new solid oral tablet formulation of posaconazole: a randomized clinical trial to investigate rising single-and multiple-dose pharmacokinetics and safety in healthy volunteers. J Antimicrob Chemother 2012; 67:2725-2730.
    • (2012) J Antimicrob Chemother , vol.67 , pp. 2725-2730
    • Krishna, G.1    Ma, L.2    Martinho, M.3
  • 105
    • 0041422239 scopus 로고    scopus 로고
    • Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults
    • Courtney R, Pai S, Laughlin M, et al. Pharmacokinetics, safety, and tolerability of oral posaconazole administered in single and multiple doses in healthy adults. Antimicrob Agents Chemother 2003; 47:2788-2795.
    • (2003) Antimicrob Agents Chemother , vol.47 , pp. 2788-2795
    • Courtney, R.1    Pai, S.2    Laughlin, M.3
  • 106
    • 84887448895 scopus 로고    scopus 로고
    • Antifungal prophylaxis with posaconazole in patients with acute myeloid leukemia: Dose intensification coupled with avoidance of proton pump inhibitors is beneficial in shortening time to effective concentrations
    • Cojutti P, Candoni A, Simeone E, et al. Antifungal prophylaxis with posaconazole in patients with acute myeloid leukemia: dose intensification coupled with avoidance of proton pump inhibitors is beneficial in shortening time to effective concentrations. Antimicrob Agents Chemother 2013; 57:6081-6084.
    • (2013) Antimicrob Agents Chemother , vol.57 , pp. 6081-6084
    • Cojutti, P.1    Candoni, A.2    Simeone, E.3
  • 107
    • 84903180158 scopus 로고    scopus 로고
    • Phase 1B study of the pharmacokinetics and safety of posaconazole intravenous solution in patients at risk for invasive fungal disease
    • Maertens J, Cornely OA, Ullmann AJ, et al. Phase 1B study of the pharmacokinetics and safety of posaconazole intravenous solution in patients at risk for invasive fungal disease. Antimicrob Agents Chemother 2014; 58:3610-3617.
    • (2014) Antimicrob Agents Chemother , vol.58 , pp. 3610-3617
    • Maertens, J.1    Cornely, O.A.2    Ullmann, A.J.3
  • 108
    • 54749151049 scopus 로고    scopus 로고
    • Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome
    • Krishna G, AbuTarif M, Xuan F, et al. Pharmacokinetics of oral posaconazole in neutropenic patients receiving chemotherapy for acute myelogenous leukemia or myelodysplastic syndrome. Pharmacotherapy 2008; 28:1223-1232.
    • (2008) Pharmacotherapy , vol.28 , pp. 1223-1232
    • Krishna, G.1    Abutarif, M.2    Xuan, F.3
  • 109
    • 36849064207 scopus 로고    scopus 로고
    • Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease
    • Krishna G, Martinho M, Chandrasekar P, et al. Pharmacokinetics of oral posaconazole in allogeneic hematopoietic stem cell transplant recipients with graft-versus-host disease. Pharmacotherapy 2007; 27:1627-1636.
    • (2007) Pharmacotherapy , vol.27 , pp. 1627-1636
    • Krishna, G.1    Martinho, M.2    Chandrasekar, P.3
  • 110
    • 84864286296 scopus 로고    scopus 로고
    • Factors influencing the pharmacokinetics of prophylactic posaconazole oral suspension in patients with acute myeloid leukemia or myelodysplastic syndrome
    • Vehreschild JJ, Mü ller C, Farowski F, et al. Factors influencing the pharmacokinetics of prophylactic posaconazole oral suspension in patients with acute myeloid leukemia or myelodysplastic syndrome. Eur J Clin Pharmacol 2012; 68:987-995.
    • (2012) Eur J Clin Pharmacol , vol.68 , pp. 987-995
    • Vehreschild, J.J.1    Mü Ller, C.2    Farowski, F.3
  • 111
    • 77956343542 scopus 로고    scopus 로고
    • An insight into the antifungal pipeline: Selected new molecules and beyond
    • Ostrosky-Zeichner L, Casadevall A, Galgiani J, et al. An insight into the antifungal pipeline: selected new molecules and beyond. Nat Rev Drug Discov 2010; 9:719-727.
    • (2010) Nat Rev Drug Discov , vol.9 , pp. 719-727
    • Ostrosky-Zeichner, L.1    Casadevall, A.2    Galgiani, J.3
  • 114
    • 78049352249 scopus 로고    scopus 로고
    • Isavuconazole: A comprehensive review of spectrum of activity of a new triazole
    • Thompson GR, Wiederhold NP. Isavuconazole: a comprehensive review of spectrum of activity of a new triazole. Mycopathologia 2010; 170:291-313.
    • (2010) Mycopathologia , vol.170 , pp. 291-313
    • Thompson, G.R.1    Wiederhold, N.P.2
  • 115
    • 84862062156 scopus 로고    scopus 로고
    • Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections
    • Livermore J, Hope W. Evaluation of the pharmacokinetics and clinical utility of isavuconazole for treatment of invasive fungal infections. Expert Opin Drug Metab Toxicol 2012; 8:759-765.
    • (2012) Expert Opin Drug Metab Toxicol , vol.8 , pp. 759-765
    • Livermore, J.1    Hope, W.2
  • 116
    • 84866450510 scopus 로고    scopus 로고
    • Effect of rifampicin on the pharmacokinetics of BAL4815 at steady state after multiple oral daily doses of BAL8557 (WSA) and rifampicin
    • Paris, France
    • Schmitt-Hoffman, Roos B, Sauer J. Effect of rifampicin on the pharmacokinetics of BAL4815 at steady state after multiple oral daily doses of BAL8557 (WSA) and rifampicin. In: 16th Congress of the International Society of Human and Animal Mycology; 2006; Paris, France.
    • (2006) 16th Congress of the International Society of Human and Animal Mycology
    • Schmitt-Hoffman1    Roos, B.2    Sauer, J.3


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