Impact of absolute stereochemistry on the antiangiogenic and antifungal activities of itraconazole

ACS Medicinal Chemistry Letters

Volumn 1, Issue 4, 2010, Pages 155-159

  Shi, Wei ^a   Nacev, Benjamin A ^a   Bhat, Shridhar ^a   Liu, Jun O ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

angiogenesis; antifungal activity; diastereomers; Itraconazole; stereochemistry

Indexed keywords

ANGIOGENESIS INHIBITOR; ANTIFUNGAL AGENT; ITRACONAZOLE; ITRACONAZOLE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIANGIOGENIC ACTIVITY; ANTIFUNGAL ACTIVITY; ARTICLE; CANDIDA ALBICANS; CANDIDA GLABRATA; CARBON NUCLEAR MAGNETIC RESONANCE; CELL PROLIFERATION; CRYPTOCOCCUS NEOFORMANS; DIASTEREOISOMER; DRUG POTENCY; DRUG SYNTHESIS; ENDOTHELIUM CELL; FUNGAL STRAIN; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; OPTICAL ROTATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SACCHAROMYCES CEREVISIAE; STEREOCHEMISTRY; STEREOISOMERISM;

EID: 77955905585     PISSN: None     EISSN: 19485875     Source Type: Journal    
DOI: 10.1021/ml1000068     Document Type: Article

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