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Volumn 24, Issue 5, 1999, Pages 339-346

Gender-related differences in pharmacokinetics and their clinical significance

Author keywords

[No Author keywords available]

Indexed keywords

AMINOPHYLLINE; AMITRIPTYLINE; CARBAMAZEPINE; CHLORZOXAZONE; CITALOPRAM; CLOMIPRAMINE; CYCLOSPORIN; CYTOCHROME P450 ISOENZYME; DAPSONE; DIAZEPAM; DIGOXIN; ERYTHROMYCIN; IMIPRAMINE; ISONIAZID; LIDOCAINE; MEPHENYTOIN; METHYLPHENOBARBITAL; MIDAZOLAM; NAPROXEN; PARACETAMOL; PHENYTOIN; PROPRANOLOL; STEROID HORMONE; THEOPHYLLINE; TIOTIXENE; TOLBUTAMIDE; TRIAZOLAM; WARFARIN;

EID: 0032731634     PISSN: 02694727     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2710.1999.00246.x     Document Type: Review
Times cited : (242)

References (91)
  • 2
    • 0021322739 scopus 로고
    • Sex-related differences in drug disposition in man
    • 2. Wilson K. (1984) Sex-related differences in drug disposition in man. Clinical Pharmacokinetics, 9, 189-202.
    • (1984) Clinical Pharmacokinetics , vol.9 , pp. 189-202
    • Wilson, K.1
  • 3
    • 0026091233 scopus 로고
    • Gender-related differences in xenobiotic metabolism
    • 3. Bonate PL. (1991) Gender-related differences in xenobiotic metabolism. Journal of Clinical Pharmacology, 31, 684-690.
    • (1991) Journal of Clinical Pharmacology , vol.31 , pp. 684-690
    • Bonate, P.L.1
  • 4
    • 0029128720 scopus 로고
    • Gender effects in pharmacokinetics and pharmacodynamics
    • 4. Harris RZ, Benet LZ, Schwartz JB. (1995) Gender effects in pharmacokinetics and pharmacodynamics. Drugs, 50, 222-239.
    • (1995) Drugs , vol.50 , pp. 222-239
    • Harris, R.Z.1    Benet, L.Z.2    Schwartz, J.B.3
  • 6
    • 0031891641 scopus 로고    scopus 로고
    • Physiological changes during the menstrual cycle and their effects on the pharmacokinetics and pharmacodynamics of drugs
    • 6. Kashuba AD, Nafziger AN. (1998) Physiological changes during the menstrual cycle and their effects on the pharmacokinetics and pharmacodynamics of drugs. Clinical Pharmacokinetics, 34, 203-218.
    • (1998) Clinical Pharmacokinetics , vol.34 , pp. 203-218
    • Kashuba, A.D.1    Nafziger, A.N.2
  • 7
    • 0025368334 scopus 로고
    • Pharmacokinetic drug interactions with oral contraceptives
    • 7. Back DJ, Orme ML. (1990) Pharmacokinetic drug interactions with oral contraceptives. Clinical Pharmacokinetics, 18, 472-484.
    • (1990) Clinical Pharmacokinetics , vol.18 , pp. 472-484
    • Back, D.J.1    Orme, M.L.2
  • 8
    • 0025647583 scopus 로고
    • Differences in drug metabolism polymorphism between Orientals and Caucasians
    • 8. Lou YC. (1990) Differences in drug metabolism polymorphism between Orientals and Caucasians. Drug Metabolism Reviews, 22, 451-475.
    • (1990) Drug Metabolism Reviews , vol.22 , pp. 451-475
    • Lou, Y.C.1
  • 10
    • 0025265648 scopus 로고
    • Molecular genetics and the future of pharmacogenetics
    • 10. Meyer UA. (1990) Molecular genetics and the future of pharmacogenetics. Pharmacology and Therapeutics, 46, 349-355.
    • (1990) Pharmacology and Therapeutics , vol.46 , pp. 349-355
    • Meyer, U.A.1
  • 11
    • 0025036495 scopus 로고
    • Prediction of xenobiotic metabolism by non-invasive methods
    • 11. Loft S, Poulsen HE. (1990) Prediction of xenobiotic metabolism by non-invasive methods. Pharmacology and Toxicology, 67, 101-108.
    • (1990) Pharmacology and Toxicology , vol.67 , pp. 101-108
    • Loft, S.1    Poulsen, H.E.2
  • 12
    • 0025688972 scopus 로고
    • Role of cytochrome P450 in drug metabolism and hepatotoxicity
    • 12. Watkins PB. (1990) Role of cytochrome P450 in drug metabolism and hepatotoxicity. Seminars in Liver Disease, 10, 235-250.
    • (1990) Seminars in Liver Disease , vol.10 , pp. 235-250
    • Watkins, P.B.1
  • 13
    • 0025758615 scopus 로고
    • Ethnic differences in drug disposition and responsiveness
    • 13. Wood AJJ, Zhou HH. (1991) Ethnic differences in drug disposition and responsiveness. Clinical Pharmacokinetics, 20, 350-373.
    • (1991) Clinical Pharmacokinetics , vol.20 , pp. 350-373
    • Wood, A.J.J.1    Zhou, H.H.2
  • 14
    • 0026496950 scopus 로고
    • The role of individual human cytochrome P450 in drug metabolism and clinical response
    • 14. Cholerton S, Daly AK, Idle JR. (1992) The role of individual human cytochrome P450 in drug metabolism and clinical response. Trends in Pharmacological Sciences, 13, 434-439.
    • (1992) Trends in Pharmacological Sciences , vol.13 , pp. 434-439
    • Cholerton, S.1    Daly, A.K.2    Idle, J.R.3
  • 15
    • 0026569805 scopus 로고
    • Cytochrome P-450 in rat: Structures, functions, properties and relevant human forms
    • 15. Soucek P, Gut I. (1992) Cytochrome P-450 in rat: structures, functions, properties and relevant human forms. Xenobiotica, 22, 83-103.
    • (1992) Xenobiotica , vol.22 , pp. 83-103
    • Soucek, P.1    Gut, I.2
  • 16
    • 0026750647 scopus 로고
    • The human hepatic cytochromes P450 involved in drug metabolism
    • 16. Wrighton SA, Stevens JC. (1992) The human hepatic cytochromes P450 involved in drug metabolism. Critical Reviews in Toxicology, 22, 1-21.
    • (1992) Critical Reviews in Toxicology , vol.22 , pp. 1-21
    • Wrighton, S.A.1    Stevens, J.C.2
  • 17
  • 18
    • 0028071759 scopus 로고
    • Noninvasive tests of CYP3A enzymes
    • 18. Watokins PB. (1994) Noninvasive tests of CYP3A enzymes. Pharmacogenetics, 4, 171-184.
    • (1994) Pharmacogenetics , vol.4 , pp. 171-184
    • Watokins, P.B.1
  • 19
    • 0029028932 scopus 로고
    • Geographical/interracial differences in polymorphic drug oxidation
    • 19. Bertolsson L. (1995) Geographical/interracial differences in polymorphic drug oxidation. Clinical Pharmacokinetics, 29, 192-209.
    • (1995) Clinical Pharmacokinetics , vol.29 , pp. 192-209
    • Bertolsson, L.1
  • 23
    • 0030428256 scopus 로고    scopus 로고
    • Cytochrome P4503a (CYP3A) metabolism: Prediction of in vivo activity in humans
    • 23. Wilkinson GR. (1996) Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans. Journal of Pharmacokinetics and Biopharmaceutics, 24, 475-490.
    • (1996) Journal of Pharmacokinetics and Biopharmaceutics , vol.24 , pp. 475-490
    • Wilkinson, G.R.1
  • 26
    • 0031023815 scopus 로고    scopus 로고
    • Pharmacogenetics: A laboratory tool for optimizing therapeutic efficiency
    • 26. Linder MW, Prough RA, Valdes R. (1997) Pharmacogenetics: a laboratory tool for optimizing therapeutic efficiency. Clinical Chemistry, 43, 254-266.
    • (1997) Clinical Chemistry , vol.43 , pp. 254-266
    • Linder, M.W.1    Prough, R.A.2    Valdes, R.3
  • 27
    • 0022178173 scopus 로고
    • Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian population
    • 27. Nakamura K, Goto F, Ray WA, et al. (1985) Interethnic differences in genetic polymorphism of debrisoquin and mephenytoin hydroxylation between Japanese and Caucasian population. Clinical Pharmacology and Therapeutics, 38, 402-408.
    • (1985) Clinical Pharmacology and Therapeutics , vol.38 , pp. 402-408
    • Nakamura, K.1    Goto, F.2    Ray, W.A.3
  • 29
    • 0026506140 scopus 로고
    • Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin
    • 29. Bertilsson L, Lou YQ, Du YL, et al. (1992) Pronounced differences between native Chinese and Swedish populations in the polymorphic hydroxylations of debrisoquin and S-mephenytoin. Clinical Pharmacology and Therapeutics, 51, 388-397.
    • (1992) Clinical Pharmacology and Therapeutics , vol.51 , pp. 388-397
    • Bertilsson, L.1    Lou, Y.Q.2    Du, Y.L.3
  • 30
    • 0027445449 scopus 로고
    • Isolation and characterization of human liver cytochrome P4502C19: Correlation between 2C19 and S-mephenytoin hydroxylation
    • 30. Wrighton SA, Stevens JC, Becker GW, Vanden-Branden M. (1993) Isolation and characterization of human liver cytochrome P4502C19: correlation between 2C19 and S-mephenytoin hydroxylation. Archives of Biochemistry and Biophysics, 306, 240-245.
    • (1993) Archives of Biochemistry and Biophysics , vol.306 , pp. 240-245
    • Wrighton, S.A.1    Stevens, J.C.2    Becker, G.W.3    Vanden-Branden, M.4
  • 33
    • 0024359574 scopus 로고
    • Clinical significance of the sparteine/debrisoquine oxidation polymorphism
    • 33. Brøsen K, Gram LF. (1989) Clinical significance of the sparteine/debrisoquine oxidation polymorphism. European Journal of Clinical Pharmacology, 36, 537-547.
    • (1989) European Journal of Clinical Pharmacology , vol.36 , pp. 537-547
    • Brøsen, K.1    Gram, L.F.2
  • 34
    • 0025259226 scopus 로고
    • The genetic polymorphism of debrisoquine/sparteine metabolism: Molecular mechanisms
    • 34. Meyer UA, Skoda RC, Zanger UM. (1990) The genetic polymorphism of debrisoquine/sparteine metabolism: molecular mechanisms. Pharmacology and Therapeutics, 46, 297-308.
    • (1990) Pharmacology and Therapeutics , vol.46 , pp. 297-308
    • Meyer, U.A.1    Skoda, R.C.2    Zanger, U.M.3
  • 35
    • 0025305464 scopus 로고
    • The genetic polymorphism of debrisoquine/sparteine metabolism: Clinical aspects
    • 35. Eichelbaum M, Gross AS. (1990) The genetic polymorphism of debrisoquine/sparteine metabolism: clinical aspects. Pharmacology and Therapeutics, 46, 377-394.
    • (1990) Pharmacology and Therapeutics , vol.46 , pp. 377-394
    • Eichelbaum, M.1    Gross, A.S.2
  • 36
    • 0025168860 scopus 로고
    • Genetic polymorphism of sparteine/debrisoquine oxidation: A reappraisal
    • 36. Lennard MS. (1990) Genetic polymorphism of sparteine/debrisoquine oxidation: a reappraisal. Pharmacology and Toxicology, 67, 273-283.
    • (1990) Pharmacology and Toxicology , vol.67 , pp. 273-283
    • Lennard, M.S.1
  • 38
    • 0021179863 scopus 로고
    • Dextromethorphan as a safe probe for debrisoquine hydroxylation polymorphism
    • 38. Kupfer A, Schmidt B, Preisig R, Pfaff G. (1984) Dextromethorphan as a safe probe for debrisoquine hydroxylation polymorphism. Lancet, 2, 517-518.
    • (1984) Lancet , vol.2 , pp. 517-518
    • Kupfer, A.1    Schmidt, B.2    Preisig, R.3    Pfaff, G.4
  • 39
    • 0027265750 scopus 로고
    • CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans
    • 39. Jacqz-Aigrain E, Funck-Brentano C, Cresteil T. (1993) CYP2D6- and CYP3A-dependent metabolism of dextromethorphan in humans. Pharmacogenetics, 3, 197-204.
    • (1993) Pharmacogenetics , vol.3 , pp. 197-204
    • Jacqz-Aigrain, E.1    Funck-Brentano, C.2    Cresteil, T.3
  • 40
    • 0028934224 scopus 로고
    • Dextromethorphan polymorphic hepatic oxidation (CYP2D6) in healthy black American adult subjects
    • 40. Marinac JS, Foxworth JW, Willsie SK. (1995) Dextromethorphan polymorphic hepatic oxidation (CYP2D6) in healthy black American adult subjects. Therapeutic Drug Monitoring, 17, 120-124.
    • (1995) Therapeutic Drug Monitoring , vol.17 , pp. 120-124
    • Marinac, J.S.1    Foxworth, J.W.2    Willsie, S.K.3
  • 41
    • 0024593072 scopus 로고
    • Characterization of human microsomal cytochrome P-450 enzymes
    • 41. Guengerich FP. (1989) Characterization of human microsomal cytochrome P-450 enzymes. Annual Review of Pharmacology and Toxicology, 29, 241-264.
    • (1989) Annual Review of Pharmacology and Toxicology , vol.29 , pp. 241-264
    • Guengerich, F.P.1
  • 42
    • 0026290294 scopus 로고
    • Human cytochromes P450: Evolution, catalytic activities and interindividual variations in expression
    • 42. Gonzalez FJ, Gelboin HV. (1991) Human cytochromes P450: evolution, catalytic activities and interindividual variations in expression. Progress in Clinical and Biological Research, 372, 11-20.
    • (1991) Progress in Clinical and Biological Research , vol.372 , pp. 11-20
    • Gonzalez, F.J.1    Gelboin, H.V.2
  • 43
    • 0026621673 scopus 로고
    • Racial and gender differences in N-acetyltransferase, xanthine oxidase, and CYP1A2 activities
    • 43. Relling MV, Lin JS, Ayers GD, Evans WE. (1992) Racial and gender differences in N-acetyltransferase, xanthine oxidase, and CYP1A2 activities. Clinical Pharmacology and Therapeutics, 52, 643-658.
    • (1992) Clinical Pharmacology and Therapeutics , vol.52 , pp. 643-658
    • Relling, M.V.1    Lin, J.S.2    Ayers, G.D.3    Evans, W.E.4
  • 44
    • 0025833549 scopus 로고
    • Thiothixene pharmacokinetic interactions: A study of hepatic enzyme inducers, clearance inhibitors, and demographic variables
    • 44. Ereshefsky L, Saklad SR, Watanabe MD, Davis CM, Jann MW. (1991) Thiothixene pharmacokinetic interactions: a study of hepatic enzyme inducers, clearance inhibitors, and demographic variables. Journal of Clinical Psychopharmacology, 11, 296-301.
    • (1991) Journal of Clinical Psychopharmacology , vol.11 , pp. 296-301
    • Ereshefsky, L.1    Saklad, S.R.2    Watanabe, M.D.3    Davis, C.M.4    Jann, M.W.5
  • 46
    • 0025132004 scopus 로고
    • The effect of sex and cardiac failure on the pharmacokinetics of a slow-release theophylline formulation in the elderly
    • 46. Cuzzolin L, Schinella M, Tellini U, Pezzoli L, Lippi U, Benoni G. (1990) The effect of sex and cardiac failure on the pharmacokinetics of a slow-release theophylline formulation in the elderly. Pharmacological Research, 22(Suppl. 1), 137-138.
    • (1990) Pharmacological Research , vol.22 , Issue.SUPPL. 1 , pp. 137-138
    • Cuzzolin, L.1    Schinella, M.2    Tellini, U.3    Pezzoli, L.4    Lippi, U.5    Benoni, G.6
  • 48
    • 0022966361 scopus 로고
    • Piroxicam and naproxen plasma concentrations in patients with osteoarthritis: Relation to age, sex, efficacy and adverse events
    • 48. Rugstad HE, Hundal O, Holme I, Herland OB, Husby G, Giercksky KE. (1986) Piroxicam and naproxen plasma concentrations in patients with osteoarthritis: relation to age, sex, efficacy and adverse events. Clinical Rheumatology, 5, 389-398.
    • (1986) Clinical Rheumatology , vol.5 , pp. 389-398
    • Rugstad, H.E.1    Hundal, O.2    Holme, I.3    Herland, O.B.4    Husby, G.5    Giercksky, K.E.6
  • 49
    • 0016341330 scopus 로고
    • Effects of age, sex, obesity, and pregnancy on plasma diphenylhydantoin levels
    • 49. Sherwin AL, Loynd JS, Bock GW, Sokolowski CD. (1974) Effects of age, sex, obesity, and pregnancy on plasma diphenylhydantoin levels. Epilepsia, 15, 507-521.
    • (1974) Epilepsia , vol.15 , pp. 507-521
    • Sherwin, A.L.1    Loynd, J.S.2    Bock, G.W.3    Sokolowski, C.D.4
  • 50
    • 0015373343 scopus 로고
    • Variation in response to anticonvulsants in a group of epileptic patients
    • 50. Travers RD, Reynolds EH, Gallagher BB. (1972) Variation in response to anticonvulsants in a group of epileptic patients. Archives of Neurology, 27, 29-33.
    • (1972) Archives of Neurology , vol.27 , pp. 29-33
    • Travers, R.D.1    Reynolds, E.H.2    Gallagher, B.B.3
  • 51
    • 0016721610 scopus 로고
    • Effect of age, height, weight and sex on serum phenytoin concentration in epileptic patients
    • 51. Houghton GW, Richens A, Leighton M. (1975) Effect of age, height, weight and sex on serum phenytoin concentration in epileptic patients. British Journal of Clinical Pharmacology, 2, 251-256.
    • (1975) British Journal of Clinical Pharmacology , vol.2 , pp. 251-256
    • Houghton, G.W.1    Richens, A.2    Leighton, M.3
  • 52
    • 0032905234 scopus 로고    scopus 로고
    • Clinically significant pharmacokinetic drug interactions with psychoactive drugs: Antidepressants and antipsychotics and the cytochrome P450 system
    • 52. Tanaka E. (1999) Clinically significant pharmacokinetic drug interactions with psychoactive drugs: antidepressants and antipsychotics and the cytochrome P450 system. Journal of Clinical Pharmacy and Therapeutics, 24, 7-16.
    • (1999) Journal of Clinical Pharmacy and Therapeutics , vol.24 , pp. 7-16
    • Tanaka, E.1
  • 53
    • 0032735971 scopus 로고    scopus 로고
    • Clinically significant pharmacokinetic drug interactions with benzodiazepines
    • 53. Tanaka E. (1999) Clinically significant pharmacokinetic drug interactions with benzodiazepines. Journal of Clinical Pharmacy and Therapeutics, 24, 347-355.
    • (1999) Journal of Clinical Pharmacy and Therapeutics , vol.24 , pp. 347-355
    • Tanaka, E.1
  • 54
    • 0025614555 scopus 로고
    • The influence of age and gender on the stereoselective metabolism and pharmacokinetics of mephobarbital in humans
    • 54. Hooper WD, Qing MS. (1990) The influence of age and gender on the stereoselective metabolism and pharmacokinetics of mephobarbital in humans. Clinical Pharmacology and Therapeutics, 48, 633-640.
    • (1990) Clinical Pharmacology and Therapeutics , vol.48 , pp. 633-640
    • Hooper, W.D.1    Qing, M.S.2
  • 55
    • 0027739383 scopus 로고
    • A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal anti-inflammatory drugs
    • 55. Leemann TD, Transon C, Bonnabry P, Dayer P. (1993) A major role for cytochrome P450TB (CYP2C subfamily) in the actions of non-steroidal anti-inflammatory drugs. Drugs Under Experimental and Clinical Research, 19, 189-195.
    • (1993) Drugs Under Experimental and Clinical Research , vol.19 , pp. 189-195
    • Leemann, T.D.1    Transon, C.2    Bonnabry, P.3    Dayer, P.4
  • 57
    • 0028237981 scopus 로고
    • Frequency distribution of dapsone n-hydroxylase, a putative probe for P4503a4 activity, in a white population
    • 57. May DG, Porter J, Wilkinson GR, Branch RA. (1994) Frequency distribution of dapsone N-hydroxylase, a putative probe for P4503A4 activity, in a white population. Clinical Pharmacology and Therapeutics, 55, 492-500.
    • (1994) Clinical Pharmacology and Therapeutics , vol.55 , pp. 492-500
    • May, D.G.1    Porter, J.2    Wilkinson, G.R.3    Branch, R.A.4
  • 59
    • 0025090955 scopus 로고
    • Clomipramine metabolism. Model-based analysis of variability factors from drug monitoring data
    • 59. Gex-Fabry M, Balant-Gorgia AE, Balant LP, Garrone G. (1990) Clomipramine metabolism. Model-based analysis of variability factors from drug monitoring data. Clinical Pharmacokinetics, 19, 241-255.
    • (1990) Clinical Pharmacokinetics , vol.19 , pp. 241-255
    • Gex-Fabry, M.1    Balant-Gorgia, A.E.2    Balant, L.P.3    Garrone, G.4
  • 61
    • 0024325077 scopus 로고
    • Pathway-selective sex differences in the metabolic clearance of propranolol in human subjects
    • 61. Walle T, Walle UK, Cowart TD, Conradi EC. (1989) Pathway-selective sex differences in the metabolic clearance of propranolol in human subjects. Clinical Pharmacology and Therapeutics, 46, 257-263.
    • (1989) Clinical Pharmacology and Therapeutics , vol.46 , pp. 257-263
    • Walle, T.1    Walle, U.K.2    Cowart, T.D.3    Conradi, E.C.4
  • 64
    • 0026567713 scopus 로고
    • Oxidative and reductive metabolism by cytochrome P450 2E1
    • 64. Koop DR. (1992) Oxidative and reductive metabolism by cytochrome P450 2E1. FASEB Journal, 6, 724-730.
    • (1992) FASEB Journal , vol.6 , pp. 724-730
    • Koop, D.R.1
  • 65
    • 0016776404 scopus 로고
    • Kinetic studies on sex difference in susceptibility to chronic benzene intoxication - With special reference to body fat content
    • 65. Sato A, Nakajima T, Fujiwara Y, Murayama N. (1975) Kinetic studies on sex difference in susceptibility to chronic benzene intoxication - with special reference to body fat content. British Journal of Industrial Medicine, 32, 321-328.
    • (1975) British Journal of Industrial Medicine , vol.32 , pp. 321-328
    • Sato, A.1    Nakajima, T.2    Fujiwara, Y.3    Murayama, N.4
  • 66
    • 0029035739 scopus 로고    scopus 로고
    • Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms
    • 66. Kim RB, O'Shea D, Wilkinson GR. (1996) Interindividual variability of chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphisms. Clinical Pharmacology and Therapeutics, 57, 645-655.
    • (1996) Clinical Pharmacology and Therapeutics , vol.57 , pp. 645-655
    • Kim, R.B.1    O'Shea, D.2    Wilkinson, G.R.3
  • 69
    • 0030428256 scopus 로고    scopus 로고
    • Cytochrome P4503A (CYP3A) metabolism: Prediction of in vivo activity in humans
    • 69. Wilkinson GR. (1996) Cytochrome P4503A (CYP3A) metabolism: prediction of in vivo activity in humans. Journal of Pharmacokinetics and Biopharmaceutics, 24, 475-490.
    • (1996) Journal of Pharmacokinetics and Biopharmaceutics , vol.24 , pp. 475-490
    • Wilkinson, G.R.1
  • 71
    • 0030759151 scopus 로고
    • Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe
    • 71. Kharasch ED, Russell M, Garton K, Lentz G, Bowdle TA, Cox K. (1977) Assessment of cytochrome P450 3A4 activity during the menstrual cycle using alfentanil as a noninvasive probe. Anaesthesiology, 87, 26-35.
    • (1977) Anaesthesiology , vol.87 , pp. 26-35
    • Kharasch, E.D.1    Russell, M.2    Garton, K.3    Lentz, G.4    Bowdle, T.A.5    Cox, K.6
  • 72
    • 0031706585 scopus 로고    scopus 로고
    • Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam
    • 72. Kashuba AD, Bertino JS Jr, Rocci ML Jr, Kulawy RW, Beck DJ, Nafziger AN. (1998) Quantification of 3-month intraindividual variability and the influence of sex and menstrual cycle phase on CYP3A activity as measured by phenotyping with intravenous midazolam. Clinical Pharmacology and Therapeutics, 64, 269-277.
    • (1998) Clinical Pharmacology and Therapeutics , vol.64 , pp. 269-277
    • Kashuba, A.D.1    Bertino J.S., Jr.2    Rocci M.L., Jr.3    Kulawy, R.W.4    Beck, D.J.5    Nafziger, A.N.6
  • 74
    • 0024247094 scopus 로고
    • Effects of age, gender and oral contraceptives on intramuscular midazolam pharmacokinetics
    • 74. Holazo AA, Winkler MB, Patel IH. (1988) Effects of age, gender and oral contraceptives on intramuscular midazolam pharmacokinetics. Journal of Clinical Pharmacology, 28, 1040-1045.
    • (1988) Journal of Clinical Pharmacology , vol.28 , pp. 1040-1045
    • Holazo, A.A.1    Winkler, M.B.2    Patel, I.H.3
  • 76
    • 0026732029 scopus 로고
    • Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity
    • 76. Watkins PB, Turgeon DK, Saenger P, et al. (1992) Comparison of urinary 6-beta-cortisol and the erythromycin breath test as measures of hepatic P450IIIA (CYP3A) activity. Clinical Pharmacology and Therapeutics, 52, 265-273.
    • (1992) Clinical Pharmacology and Therapeutics , vol.52 , pp. 265-273
    • Watkins, P.B.1    Turgeon, D.K.2    Saenger, P.3
  • 78
    • 0021222832 scopus 로고
    • Alterations in prednisolone disposition as a result of time of administration, gender and dose
    • 78. Meffin PJ, Brooks PM, Sallustio BC. (1984) Alterations in prednisolone disposition as a result of time of administration, gender and dose. British Journal of Clinical Pharmacology, 17, 395-404.
    • (1984) British Journal of Clinical Pharmacology , vol.17 , pp. 395-404
    • Meffin, P.J.1    Brooks, P.M.2    Sallustio, B.C.3
  • 79
    • 0027365895 scopus 로고
    • Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics
    • 79. Lew KH, Ludwig EA, Milad MA, et al. (1993) Gender-based effects on methylprednisolone pharmacokinetics and pharmacodynamics. Clinical Pharmacology and Therapeutics, 54, 402-414.
    • (1993) Clinical Pharmacology and Therapeutics , vol.54 , pp. 402-414
    • Lew, K.H.1    Ludwig, E.A.2    Milad, M.A.3
  • 83
    • 0026705762 scopus 로고
    • Digoxin population pharmacokinetics from routine clinical data: Role of patient characteristics for estimating dosing regimens
    • 83. Yukawa E, Mine H, Higuchi S, Aoyama T. (1992) Digoxin population pharmacokinetics from routine clinical data: role of patient characteristics for estimating dosing regimens. Journal of Pharmacy and Pharmacology, 44, 761-765.
    • (1992) Journal of Pharmacy and Pharmacology , vol.44 , pp. 761-765
    • Yukawa, E.1    Mine, H.2    Higuchi, S.3    Aoyama, T.4
  • 84
    • 0021224495 scopus 로고
    • Gender and oral contraceptive steroids as determinants of drug glucuronidation: Effects on clofibric acid elimination
    • 84. Miners JO, Robson RA, Birkett DJ. (1984) Gender and oral contraceptive steroids as determinants of drug glucuronidation: effects on clofibric acid elimination. British Journal of Clinical Pharmacology, 18, 240-243.
    • (1984) British Journal of Clinical Pharmacology , vol.18 , pp. 240-243
    • Miners, J.O.1    Robson, R.A.2    Birkett, D.J.3
  • 86
    • 0031810509 scopus 로고    scopus 로고
    • Developmental expression of cytochrome P450 enzymes in human liver
    • 86. Hakkola A, Tanaka E, Pelkonen O. (1998) Developmental expression of cytochrome P450 enzymes in human liver. Pharmacology and Toxicology, 82, 209-217.
    • (1998) Pharmacology and Toxicology , vol.82 , pp. 209-217
    • Hakkola, A.1    Tanaka, E.2    Pelkonen, O.3
  • 87
    • 0031783832 scopus 로고    scopus 로고
    • In vivo age-related changes in hepatic drug-oxidizing capacity in humans
    • 87. Tanaka E. (1998) In vivo age-related changes in hepatic drug-oxidizing capacity in humans. Journal of Clinical Pharmacy and Therapeutics, 23, 247-256.
    • (1998) Journal of Clinical Pharmacy and Therapeutics , vol.23 , pp. 247-256
    • Tanaka, E.1
  • 88
    • 0029128788 scopus 로고
    • Age but not gender selectively affects expression of individual cytochrome p450 proteins in human liver
    • 88. George J, Byth K, Farrell GC. (1995) Age but not gender selectively affects expression of individual cytochrome P450 proteins in human liver. Biochemical Pharmacology, 50, 727-730.
    • (1995) Biochemical Pharmacology , vol.50 , pp. 727-730
    • George, J.1    Byth, K.2    Farrell, G.C.3
  • 89
    • 0026708362 scopus 로고
    • Effect of age and gender on the activity of human hepatic CYP3A
    • 89. Hunt CM, Westerkam WR, Stave GM. (1992) Effect of age and gender on the activity of human hepatic CYP3A. Biochemical Pharmacology, 44, 275-283.
    • (1992) Biochemical Pharmacology , vol.44 , pp. 275-283
    • Hunt, C.M.1    Westerkam, W.R.2    Stave, G.M.3
  • 91
    • 0028237729 scopus 로고
    • Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: Studies with liver microsomes of 30 japanese and 30 caucasians
    • 91. Shimada T, Yamazaki H, Mimura M, Inui Y, Guengerich FP. (1994) Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians. Journal of Pharmacology and Experimental Therapeutics, 270, 414-243.
    • (1994) Journal of Pharmacology and Experimental Therapeutics , vol.270 , pp. 414-1243
    • Shimada, T.1    Yamazaki, H.2    Mimura, M.3    Inui, Y.4    Guengerich, F.P.5


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