Gene expression profiles of entorhinal cortex in Alzheimer's disease

American Journal of Alzheimer's Disease and other Dementias

Volumn 29, Issue 6, 2014, Pages 526-532

  Ding, Bingqian ^a   Xi, Yan ^a   Gao, Ming ^a   Li, Zhenjiang ^a   Xu, Chenyang ^a   Fan, Shaokang ^a   He, Weiya ^a  

^a HENAN UNIVERSITY   (China)

Author keywords

Alzheimer's disease; Differentially expressed genes; Entorhinal cortex; Glycometabolism pathway

Indexed keywords

6 PHOSPHOFRUCTOKINASE; ALDOLASE A; ALDOLASE C; ATP5B PROTEIN; ATP5CI PROTEIN; ATP5D PROTEIN; ATP5GI PROTEIN; FRUCTOSE; FRUCTOSE BISPHOSPHATE ALDOLASE; MANNOSE; PHOSPHOGLUCOMUTASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CLINICAL ARTICLE; COMPARATIVE STUDY; CONTROLLED STUDY; DIFFERENTIALLY EXPRESSED GENE; DOWN REGULATION; ENTORHINAL CORTEX; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE ONTOLOGY; GLUCONEOGENESIS; GLYCOLYSIS; HUMAN; NUCLEOTIDE METABOLISM; OXIDATIVE PHOSPHORYLATION; PENTOSE PHOSPHATE CYCLE; UPREGULATION; GENE REGULATORY NETWORK; GENETIC PREDISPOSITION; GENETIC SCREENING; GENETICS; METABOLISM;

ALZHEIMER DISEASE; ENTORHINAL CORTEX; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE REGULATORY NETWORKS; GENETIC PREDISPOSITION TO DISEASE; GENETIC TESTING; HUMANS;

EID: 84927741137     PISSN: 15333175     EISSN: 19382731     Source Type: Journal    
DOI: 10.1177/1533317514523487     Document Type: Article

References (36)

1. Alzheimer's Association, Thies W, Bleiler L. 2011 Alzheimer's disease facts and figures. Alzheimers Dement. 2011;7(2):208-244.
2. Birks J. Cholinesterase inhibitors for Alzheimer's disease Cochrane Database Syst Rev. 2006;1:CD005593.
3. Wimo A, Jonsson L, Winblad B. An estimate of the worldwide prevalence and direct costs of dementia in 2003. Dement Geriatr Cogn Disord. 2006;21(3):175-181.
4. Bateman RJ, Xiong C, Benzinger TL, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. N Engl J Med. 2012;367(9):795-804.
5. Brooks WM, Lynch PJ, Ingle CC, et al. Gene expression profiles of metabolic enzyme transcripts in Alzheimer's disease. Brain Res. 2007;1127(1):127-135.
6. He X, Huang Y, Li B, Gong C-X, Schuchman EH. Deregulation of sphingolipid metabolism in Alzheimer's disease. Neurobiol Aging. 2010;31(3):398-408.
7. Mazzola JL, Sirover MA. Reduction of glyceraldehyde-3-phosphate dehydrogenase activity in Alzheimer's disease and in Huntington's disease fibroblasts. J Neurochem. 2001;76(2):442-449.
8. Augustin R, Lichtenthaler SF, Greeff M, Hansen J, Wurst W, Trümbach D. Bioinformatics identification of modules of transcription factor binding sites in Alzheimer's disease-related genes by in silico promoter analysis and microarrays. Int J Alzheimers Dis. 2011;2011:154325.
9. Suzuki WA, Amaral DG. Topographic organization of the reciprocal connections between the monkey entorhinal cortex and the perirhinal and parahippocampal cortices. J Neurosci. 1994;14(3 pt 2):1856-1877.
10. Cunningham MO, Hunt J, Middleton S, et al. Region-specific reduction in entorhinal gamma oscillations and parvalbuminimmunoreactive neurons in animal models of psychiatric illness. J Neurosci. 2006;26(10):2767-2776.
11. De Toledo-Morrell L, Goncharova I, Dickerson B, Wilson RS, Bennett DA. From healthy aging to early Alzheimer's disease: in vivo detection of entorhinal cortex atrophy. Ann N Y Acad Sci. 2000;911:240-253.
12. Du A, Schuff N, Amend D, et al. Magnetic resonance imaging of the entorhinal cortex and hippocampus in mild cognitive impairment and Alzheimer's disease. J Neurol Neurosurg Psychiatry. 2001;71(4):441-447.
13. Ribé EM, Pérez M, Puig B, et al. Accelerated amyloid deposition, neurofibrillary degeneration and neuronal loss in double mutant APP/tau transgenic mice. Neurobiol Dis. 2005;20(3):814-822.
14. Liang WS, Dunckley T, Beach TG, et al. Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain. Physiol Genomics. 2007;28(3):311-322.
15. Liang WS, Reiman EM, Valla J, et al. Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons. Proc Natl Acad Sci U S A. 2008; 105(11):4441-4446.
16. Irizarry RA, Hobbs B, Collin F, et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics. 2003;4(2):249-264.
17. Benjamini Y, Hochberg Y. Controlling the false discovery rate: a practical and powerful approach to multiple testing. J Royal Stat Soc Series B (Methodological). 1995;57(1):289-300.
18. Mutch DM, Berger A, Mansourian R, Rytz A, Roberts MA. The limit fold change model: a practical approach for selecting differentially expressed genes from microarray data. BMC Bioinformatics. 2002;3:17.
19. Ashburner M, Ball CA, Blake JA, et al. Gene ontology: tool for the unification of biology. Nat Genet. 2000;25(1):25-29.
20. Mutowo-Meullenet P, Huntley RP, Dimmer EC, et al. Use of gene ontology annotation to understand the peroxisome proteome in humans. Database(Oxford). 2013;2013:bas062.
21. QuentienMH, Delemer B, Papadimitriou DT, et al. Deficit in anterior pituitary function and variable immune deficiency (DAVID) in children presenting with adrenocorticotropin deficiency and severe infections. J Clin Endocrinol Metab. 2012;97(1):E121-E128.
22. Hosack DA, Dennis Jr G, Sherman BT, Lane HC, Lempicki RA. Identifying biological themes within lists of genes with EASE. Genome Biol. 2003;4(10):R70
23. Altermann E, Klaenhammer TR. PathwayVoyager: pathway mapping using the Kyoto Encyclopedia of Genes and Genomes (KEGG) database. BMC Genomics. 2005;6:60.
24. Shannon P, Markiel A, Ozier O, et al. Cytoscape: a software environment for integrated models of biomolecular interaction networks. Genome Res. 2003;13(11):2498-2504.
25. Heiss W, Szelies B, Kessler J, Herholz K. Abnormalities of energy metabolism in Alzheimer's disease studied with PET. Ann N Y Acad Sci. 1990;640:65-71.
26. Hoyer S, Nitsch R, Oesterreich K. Predominant abnormality in cerebral glucose utilization in late-onset dementia of the Alzheimer type: a cross-sectional comparison against advanced lateonset and incipient early-onset cases. J Neural Transm Park Dis Dement Sect. 1991;3(1):1-14.
27. Xiao S, Cao Q, Xue H, et al. Measurement of regional cerebral metabolism rate of glucose in patients with Alzheimer's disease in different levels of severity]. Zhonghua Yi Xue Za Zhi. 2005; 85(42):2975-2979.
28. Mielke R, Herholz K, Grond M, Kessler J, Heiss W. Clinical deterioration in probable Alzheimer's disease correlates with progressive metabolic impairment of association areas. Dement Geriatr Cogn Disord. 1994;5(1):36-41.
29. Kounelakis M, Zervakis M, Giakos G, Postma G, Buydens L, Kotsiakis X. On the relevance of glycolysis process on brain gliomas. IEEE J Biomed Health Inform. 2013;17(1):128-135.
30. Mutuku JM, Nose A. Changes in the contents of metabolites and enzyme activities in rice plants responding to Rhizoctonia solani Kuhn infection: activation of glycolysis and connection to phenylpropanoid pathway. Plant Cell Physiol. 2012;53(6):1017-1032.
31. Sultana R,ButterfieldDA.Role of oxidative stress in the progression of Alzheimer's disease. J AlzheimersDis. 2010;19(1):341-353.
32. Hashimoto M, Bogdanovic N, Nakagawa H, Volkmann I, Aoki M, Winblad B, et al. Analysis of microdissected neurons by 18O mass spectrometry reveals altered protein expression in Alzheimer's disease. J Cell Mol Med. 2012;16(8):1686-1700.
33. Castegna A, Aksenov M, Aksenova M, et al. Proteomic identification of oxidatively modified proteins in Alzheimer's disease brain. Part I: creatine kinase BB, glutamine synthase, and ubiquitin carboxy-terminal hydrolase L-1. Free Rad Biol Med. 2002; 33(4):562-571.
34. Aksenova M, Butterfield DA, Zhang S-X, Underwood M, Geddes JW. Increased protein oxidation and decreased creatine kinase BB expression and activity after spinal cord contusion injury. J Neurotrauma. 2002;19(4):491-502.
35. Sultana R, Perluigi M, Butterfield DA. Redox proteomics identification of oxidatively modified proteins in Alzheimer's disease brain and in vivo and in vitro models of AD centered around Ab (1-42). J Chromatogr B Analyt Technol Biomed Life Sci. 2006;833(1):3-11.
36. Lin AP, Shic F, Enriquez C, Ross BD. Reduced glutamate neurotransmission in patients with Alzheimer's disease-an in vivo 13C magnetic resonance spectroscopy study. MAGMA. 2003;16(1): 29-42.