Reduced glutamate neurotransmission in patients with Alzheimer's disease - An in vivo 13C magnetic resonance spectroscopy study

Magnetic Resonance Materials in Physics, Biology and Medicine

Volumn 16, Issue 1, 2003, Pages 29-42

  Lin, Alexander P ^a   Shic, Frederick ^b   Enriquez, Cathleen ^b   Ross, Brian D ^a  

^a HUNTINGTON MEDICAL RESEARCH INSTITUTES   (United States)

^b Rudi Schulte Research Institute   (United States)

Author keywords

13C Glucose infusion; 13C Magnetic resonance spectroscopy; Alzheimer's disease; Glutamate neurotransmission; Glutamate glutamine cycle; Mini mental state exam; N acetyl aspartate

Indexed keywords

ADENOSINE TRIPHOSPHATE; BICARBONATE; CREATINE; GLUTAMIC ACID; INOSITOL; N ACETYLASPARTIC ACID; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; CARBON; GLUCOSE; PROTON;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; BRAIN METABOLISM; BRAIN NERVE CELL; CARBON NUCLEAR MAGNETIC RESONANCE; CASE REPORT; CINGULATE GYRUS; CITRIC ACID CYCLE; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; GLUCOSE OXIDATION; GRAY MATTER; HUMAN; HYPOTHESIS; IN VIVO STUDY; MENTAL HEALTH; NEUROIMAGING; NEUROPATHOLOGY; NEUROTRANSMISSION; PATHOPHYSIOLOGY; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; QUANTITATIVE ANALYSIS; WHITE MATTER; BRAIN; BRAIN LEVEL; CHEMISTRY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; METABOLISM; METHODOLOGY; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PILOT STUDY; SYNAPTIC TRANSMISSION;

ADULT; AGED; ALZHEIMER DISEASE; BRAIN; BRAIN CHEMISTRY; CARBON ISOTOPES; GLUCOSE; GLUTAMIC ACID; HUMANS; MAGNETIC RESONANCE SPECTROSCOPY; MIDDLE AGED; NEUROTRANSMITTER AGENTS; PILOT PROJECTS; PROTONS; SYNAPTIC TRANSMISSION;

EID: 1542284679     PISSN: 09685243     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10334-003-0004-x     Document Type: Article

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