Role of positively charged residues of the second transmembrane domain in the ion transport activity and conformation of human uncoupling protein-2

Biochemistry

Volumn 54, Issue 14, 2015, Pages 2303-2313

  Hoang, Tuan ^a,b   Matovic, Tijana ^a   Parker, James ^a   Smith, Matthew D ^a,b   Jelokhani Niaraki, Masoud ^a,b  

^a WILFRID LAURIER UNIVERSITY   (Canada)

^b UNIVERSITY OF GUELPH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; AMINO ACIDS; BIOSYNTHESIS; CELL MEMBRANES; CHLORINE COMPOUNDS; FATTY ACIDS; LIPOSOMES; MITOCHONDRIA; NEGATIVE IONS; NUCLEOTIDES; PROTEINS; PROTONS;

ANION TRANSPORT FUNCTION; INNER MITOCHONDRIAL MEMBRANES; ION TRANSPORT MECHANISMS; ION TRANSPORT PATHWAYS; LONG CHAIN FATTY ACID; MITOCHONDRIAL MATRIX; SECOND TRANSMEMBRANE DOMAIN; TRANSMEMBRANE HELICES;

IONS;

CHLORIDE CHANNEL; LIPOSOME; LONG CHAIN FATTY ACID; MEMBRANE PROTEIN; UNCOUPLING PROTEIN 2; CHLORIDE; ION CHANNEL; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL UNCOUPLING PROTEIN 2; PROTON; RECOMBINANT PROTEIN;

ANION TRANSPORT; ARTICLE; CHLORIDE TRANSPORT; CONFORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME MECHANISM; ION TRANSPORT; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; PROTON TRANSPORT; STRUCTURE ACTIVITY RELATION; WILD TYPE; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; HUMAN; MUTATION; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SITE DIRECTED MUTAGENESIS;

CHLORIDES; HUMANS; ION CHANNELS; ION TRANSPORT; LIPOSOMES; MITOCHONDRIAL PROTEINS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; PROTONS; RECOMBINANT PROTEINS;

EID: 84927740393     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/acs.biochem.5b00177     Document Type: Article

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