Engineering of a superhelicase through conformational control

Science

Volumn 348, Issue 6232, 2015, Pages 344-347

  Arslan, Sinan ^a   Khafizov, Rustem ^a   Thomas, Christopher D ^b   Chemla, Yann R ^a   Ha, Taekjip ^a,c  

^a University of Illinois at Urbana Champaign   (United States)

^b UNIVERSITY OF LEEDS   (United Kingdom)

^c UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HELICASE; NUCLEIC ACID; SUPERHELICASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; CROSS LINKING REAGENT; DEOXYRIBONUCLEASE; DNA HELICASE; ESCHERICHIA COLI PROTEIN; PCRA PROTEIN, BACTERIA; REP PROTEIN, E COLI; SINGLE STRANDED DNA;

BIOTECHNOLOGY; ENZYME ACTIVITY; MOLECULAR ANALYSIS;

ARTICLE; CROSS LINKING; DNA DENATURATION; ENZYME ACTIVITY; ENZYME CONFORMATION; ENZYME ENGINEERING; ENZYME PURIFICATION; FLUORESCENCE RESONANCE ENERGY TRANSFER; GENE AMPLIFICATION; NONHUMAN; PRIORITY JOURNAL; VALIDATION STUDY; CHEMISTRY; DNA REPLICATION; ENZYME STABILITY; GENETICS; PROTEIN CONFORMATION; PROTEIN ENGINEERING; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; CROSS-LINKING REAGENTS; CRYSTALLOGRAPHY, X-RAY; DEOXYRIBONUCLEASES; DNA HELICASES; DNA REPLICATION; DNA, SINGLE-STRANDED; ENZYME STABILITY; ESCHERICHIA COLI PROTEINS; PROTEIN CONFORMATION; PROTEIN ENGINEERING;

EID: 84927740259     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa0445     Document Type: Article

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