Direct observation of structure-function relationship in a nucleic acid -processing enzyme

Science

Volumn 348, Issue 6232, 2015, Pages 352-354

  Comstock, Matthew J ^a,e   Whitley, Kevin D ^a   Jia, Haifeng ^b   Sokoloski, Joshua ^b   Lohman, Timothy M ^b   Ha, Taekjip ^a,c,d   Chemla, Yann R ^a  

^a University of Illinois at Urbana Champaign   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^e MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; HELICASE; MONOMER; NUCLEIC ACID; DNA HELICASE; ESCHERICHIA COLI PROTEIN; UVRD PROTEIN, E COLI;

ASSAY; ENZYME ACTIVITY; MEASUREMENT METHOD; NUCLEIC ACID; PROTEIN; THREE-DIMENSIONAL MODELING;

ARTICLE; BIOLOGY; BLEACHING; DNA DENATURATION; DNA HAIRPIN; ENZYME CONFORMATION; EXCISION REPAIR; FLUORESCENCE MICROSCOPY; FLUORESCENCE RESONANCE ENERGY TRANSFER; MEASUREMENT; MISMATCH REPAIR; OPTICAL TWEEZERS; PRIORITY JOURNAL; STOICHIOMETRY; STRUCTURE ACTIVITY RELATION; CHEMISTRY; DNA REPAIR; DNA REPLICATION; PHYSIOLOGY; PROCEDURES; PROTEIN CONFORMATION;

DNA HELICASES; DNA REPAIR; DNA REPLICATION; ESCHERICHIA COLI PROTEINS; MICROSCOPY, FLUORESCENCE; OPTICAL TWEEZERS; PROTEIN CONFORMATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84927716904     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aaa0130     Document Type: Article

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